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Sequences

Sequence NM_000218

GCGGCGGGGCTGGCAGCAGTGGCTGCCCGCACTGCGCCCGGGCGCTCGCCTTCGCTGCAGCTCCCGGTGCCGCCGCTCGGGCCGGCCCCCCGGCAGGCCC TCCTCGTTATGGCCGCGGCCTCCTCCCCGCCCAGGGCCGAGAGGAAGCGCTGGGGTTGGGGCCGCCTGCCAGGCGCCCGGCGGGGCAGCGCGGGCCTGGC CAAGAAGTGCCCCTTCTCGCTGGAGCTGGCGGAGGGCGGCCCGGCGGGCGGCGCGCTCTACGCGCCCATCGCGCCCGGCGCCCCAGGTCCCGCGCCCCCT GCGTCCCCGGCCGCGCCCGCCGCGCCCCCAGTTGCCTCCGACCTTGGCCCGCGGCCGCCGGTGAGCCTAGACCCGCGCGTCTCCATCTACAGCACGCGCC GCCCGGTGTTGGCGCGCACCCACGTCCAGGGCCGCGTCTACAACTTCCTCGAGCGTCCCACCGGCTGGAAATGCTTCGTTTACCACTTCGCCGTCTTCCT CATCGTCCTGGTCTGCCTCATCTTCAGCGTGCTGTCCACCATCGAGCAGTATGCCGCCCTGGCCACGGGGACTCTCTTCTGGATGGAGATCGTGCTGGTG GTGTTCTTCGGGACGGAGTACGTGGTCCGCCTCTGGTCCGCCGGCTGCCGCAGCAAGTACGTGGGCCTCTGGGGGCGGCTGCGCTTTGCCCGGAAGCCCA TTTCCATCATCGACCTCATCGTGGTCGTGGCCTCCATGGTGGTCCTCTGCGTGGGCTCCAAGGGGCAGGTGTTTGCCACGTCGGCCATCAGGGGCATCCG CTTCCTGCAGATCCTGAGGATGCTACACGTCGACCGCCAGGGAGGCACCTGGAGGCTCCTGGGCTCCGTGGTCTTCATCCACCGCCAGGAGCTGATAACC ACCCTGTACATCGGCTTCCTGGGCCTCATCTTCTCCTCGTACTTTGTGTACCTGGCTGAGAAGGACGCGGTGAACGAGTCAGGCCGCGTGGAGTTCGGCA GCTACGCAGATGCGCTGTGGTGGGGGGTGGTCACAGTCACCACCATCGGCTATGGGGACAAGGTGCCCCAGACGTGGGTCGGGAAGACCATCGCCTCCTG CTTCTCTGTCTTTGCCATCTCCTTCTTTGCGCTCCCAGCGGGGATTCTTGGCTCGGGGTTTGCCCTGAAGGTGCAGCAGAAGCAGAGGCAGAAGCACTTC AACCGGCAGATCCCGGCGGCAGCCTCACTCATTCAGACCGCATGGAGGTGCTATGCTGCCGAGAACCCCGACTCCTCCACCTGGAAGATCTACATCCGGA AGGCCCCCCGGAGCCACACTCTGCTGTCACCCAGCCCCAAACCCAAGAAGTCTGTGGTGGTAAAGAAAAAAAAGTTCAAGCTGGACAAAGACAATGGGGT GACTCCTGGAGAGAAGATGCTCACAGTCCCCCATATCACGTGCGACCCCCCAGAAGAGCGGCGGCTGGACCACTTCTCTGTCGACGGCTATGACAGTTCT GTAAGGAAGAGCCCAACACTGCTGGAAGTGAGCATGCCCCATTTCATGAGAACCAACAGCTTCGCCGAGGACCTGGACCTGGAAGGGGAGACTCTGCTGA CACCCATCACCCACATCTCACAGCTGCGGGAACACCATCGGGCCACCATTAAGGTCATTCGACGCATGCAGTACTTTGTGGCCAAGAAGAAATTCCAGCA AGCGCGGAAGCCTTACGATGTGCGGGACGTCATTGAGCAGTACTCGCAGGGCCACCTCAACCTCATGGTGCGCATCAAGGAGCTGCAGAGGAGGCTGGAC CAGTCCATTGGGAAGCCCTCACTGTTCATCTCCGTCTCAGAAAAGAGCAAGGATCGCGGCAGCAACACGATCGGCGCCCGCCTGAACCGAGTAGAAGACA AGGTGACGCAGCTGGACCAGAGGCTGGCACTCATCACCGACATGCTTCACCAGCTGCTCTCCTTGCACGGTGGCAGCACCCCCGGCAGCGGCGGCCCCCC CAGAGAGGGCGGGGCCCACATCACCCAGCCCTGCGGCAGTGGCGGCTCCGTCGACCCTGAGCTCTTCCTGCCCAGCAACACCCTGCCCACCTACGAGCAG CTGACCGTGCCCAGGAGGGGCCCCGATGAGGGGTCCTGAGGAGGGGATGGGGCTGGGGGATGGGCCTGAGTGAGAGGGGAGGCCAAGAGTGGCCCCACCT GGCCCTCTCTGAAGGAGGCCACCTCCTAAAAGGCCCAGAGAGAAGAGCCCCACTCTCAGAGGCCCCAATACCCCATGGACCATGCTGTCTGGCACAGCCT GCACTTGGGGGCTCAGCAAGGCCACCTCTTCCTGGCCGGTGTGGGGGCCCCGTCTCAGGTCTGAGTTGTTACCCCAAGCGCCCTGGCCCCCACATGGTGA TGTTGACATCACTGGCATGGTGGTTGGGACCCAGTGGCAGGGCACAGGGCCTGGCCCATGTATGGCCAGGAAGTAGCACAGGCTGAGTGCAGGCCCACCC TGCTTGGCCCAGGGGGCTTCCTGAGGGGAGACAGAGCAACCCCTGGACCCCAGCCTCAAATCCAGGACCCTGCCAGGCACAGGCAGGGCAGGACCAGCCC ACGCTGACTACAGGGCCGCCGGCAATAAAAGCCCAGGAGCCCATTTGGAGGGCCTGGGCCTGGCTCCCTCACTCTCAGGAAATGCTGACCCATGGGCAGG AGACTGTGGAGACTGCTCCTGAGCCCCCAGCTTCCAGCAGGAGGGACAGTCTCACCATTTCCCCAGGGCACGTGGTTGAGTGGGGGGAACGCCCACTTCC CTGGGTTAGACTGCCAGCTCTTCCTAGCTGGAGAGGAGCCCTGCCTCTCCGCCCCTGAGCCCACTGTGCGTGGGGCTCCCGCCTCCAACCCCTCGCCCAG TCCCAGCAGCCAGCCAAACACACAGAAGGGGACTGCCACCTCCCCTTGCCAGCTGCTGAGCCGCAGAGAAGTGACGGTTCCTACACAGGACAGGGGTTCC TTCTGGGCATTACATCGCATAGAAATCAATAATTTGTGGTGATTTGGATCTGTGTTTTAATGAGTTTCACAGTGTGATTTTGATTATTAATTGTGCAAGC TTTTCCTAATAAACGTGGAGAATCACAGGCTGGGCTGGGCACTGCTCTCACCTTGGTTCCTGGGGCATCCATGGGGTCTCTCACAGACAGGACCCCTGCA GTTCCCCTGGAAGCAGTGCCCAGGTGGCTGTGGAATAGGAACGCTA

refseq_KCNQ1.F1 (forward primer)
refseq_KCNQ1.R1 (reverse primer)
Single exon skipping

Frame 0

AAGLAAVAARTAPGRSPSLQLPVPPLGPAPRQA LLVMAAASSPPRAERKRWGWGRLPGARRGSAGLA KKCPFSLELAEGGPAGGALYAPIAPGAPGPAPP ASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTR RPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFL IVLVCLIFSVLSTIEQYAALATGTLFWMEIVLV VFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKP ISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIR FLQILRMLHVDRQGGTWRLLGSVVFIHRQELIT TLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFG SYADALWWGVVTVTTIGYGDKVPQTWVGKTIASC FSVFAISFFALPAGILGSGFALKVQQKQRQKHF NRQIPAAASLIQTAWRCYAAENPDSSTWKIYIR KAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGV TPGEKMLTVPHITCDPPEERRLDHFSVDGYDSS VRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLL TPITHISQLREHHRATIKVIRRMQYFVAKKKFQQ ARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLD QSIGKPSLFISVSEKSKDRGSNTIGARLNRVED KVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPP REGGAHITQPCGSGGSVDPELFLPSNTLPTYEQ LTVPRRGPDEGS*GGDGAGGWA*VRGEAKSGPT WPSLKEATS*KAQREEPHSQRPQYPMDHAVWHSL HLGAQQGHLFLAGVGAPSQV*VVTPSALAPTW* C*HHWHGGWDPVAGHRAWPMYGQEVAQAECRPT LLGPGGFLRGDRATPGPQPQIQDPARHRQGRTSP R*LQGRRQ*KPRSPFGGPGPGSLTLRKC*PMGR RLWRLLLSPQLPAGGTVSPFPQGTWLSGGNAHF PGLDCQLFLAGEEPCLSAPEPTVRGAPASNPSPS PSSQPNTQKGTATSPCQLLSRREVTVPTQDRGS FWALHRIEINNLW*FGSVF**VSQCDFDY*LCK LFLINVENHRLGWALLSPWFLGHPWGLSQTGPLQ FPWKQCPGGCGIGTL

Frame 1

RRGWQQWLPALRPGARLRCSSRCRRSGRPPGRP SSLWPRPPPRPGPRGSAGVGAACQAPGGAARAW PRSAPSRWSWRRAARRAARSTRPSRPAPQVPRPL RPRPRPPRPQLPPTLARGRR*A*TRASPSTARA ARCWRAPTSRAASTTSSSVPPAGNASFTTSPSS SSSWSASSSACCPPSSSMPPWPRGLSSGWRSCWW CSSGRSTWSASGPPAAAASTWASGGGCALPGSP FPSSTSSWSWPPWWSSAWAPRGRCLPRRPSGAS ASCRS*GCYTSTAREAPGGSWAPWSSSTARS**P PCTSASWASSSPRTLCTWLRRTR*TSQAAWSSA ATQMRCGGGWSQSPPSAMGTRCPRRGSGRPSPP ASLSLPSPSLRSQRGFLARGLP*RCSRSRGRSTS TGRSRRQPHSFRPHGGAMLPRTPTPPPGRSTSG RPPGATLCCHPAPNPRSLWW*RKKSSSWTKTMG *LLERRCSQSPISRATPQKSGGWTTSLSTAMTVL *GRAQHCWK*ACPIS*EPTASPRTWTWKGRLC* HPSPTSHSCGNTIGPPLRSFDACSTLWPRRNSS KRGSLTMCGTSLSSTRRATSTSWCASRSCRGGWT SPLGSPHCSSPSQKRARIAAATRSAPA*TE*KT R*RSWTRGWHSSPTCFTSCSPCTVAAPPAAAAP PERAGPTSPSPAAVAAPSTLSSSCPATPCPPTSS *PCPGGAPMRGPEEGMGLGDGPE*EGRPRVAPP GPL*RRPPPKRPREKSPTLRGPNTPWTMLSGTA CTWGLSKATSSWPVWGPRLRSELLPQAPWPPHGD VDITGMVVGTQWQGTGPGPCMARK*HRLSAGPP CLAQGAS*GETEQPLDPSLKSRTLPGTGRAGPA HADYRAAGNKSPGAHLEGLGLAPSLSGNADPWAG DCGDCS*APSFQQEGQSHHFPRARG*VGGTPTS LG*TASSS*LERSPASPPLSPLCVGLPPPTPRP VPAASQTHRRGLPPPLASC*AAEK*RFLHRTGVP SGHYIA*KSIICGDLDLCFNEFHSVILIINCAS FS**TWRITGWAGHCSHLGSWGIHGVSHRQDPC SSPGSSAQVAVE*ER

Frame 2

GGAGSSGCPHCARALAFAAAPGAAARAGPPAGP PRYGRGLLPAQGREEALGLGPPARRPAGQRGPG QEVPLLAGAGGGRPGGRRALRAHRARRPRSRAP CVPGRARRAPSCLRPWPAAAGEPRPARLHLQHAP PGVGAHPRPGPRLQLPRASHRLEMLRLPLRRLP HRPGLPHLQRAVHHRAVCRPGHGDSLLDGDRAG GVLRDGVRGPPLVRRLPQQVRGPLGAAALCPEAH FHHRPHRGRGLHGGPLRGLQGAGVCHVGHQGHP LPADPEDATRRPPGRHLEAPGLRGLHPPPGADN HPVHRLPGPHLLLVLCVPG*EGRGERVRPRGVRQ LRRCAVVGGGHSHHHRLWGQGAPDVGREDHRLL LLCLCHLLLCAPSGDSWLGVCPEGAAEAEAEAL QPADPGGSLTHSDRMEVLCCREPRLLHLEDLHPE GPPEPHSAVTQPQTQEVCGGKEKKVQAGQRQWG DSWREDAHSPPYHVRPPRRAAAGPLLCRRL*QF CKEEPNTAGSEHAPFHENQQLRRGPGPGRGDSAD THHPHLTAAGTPSGHH*GHSTHAVLCGQEEIPA SAEALRCAGRH*AVLAGPPQPHGAHQGAAEEAG PVHWEALTVHLRLRKEQGSRQQHDRRPPEPSRRQ GDAAGPEAGTHHRHASPAALLARWQHPRQRRPP QRGRGPHHPALRQWRLRRP*ALPAQQHPAHLRA ADRAQEGPR*GVLRRGWGWGMGLSERGGQEWPHL ALSEGGHLLKGPERRAPLSEAPIPHGPCCLAQP ALGGSARPPLPGRCGGPVSGLSCYPKRPGPHMV MLTSLAWWLGPSGRAQGLAHVWPGSSTG*VQAHP AWPRGLPEGRQSNPWTPASNPGPCQAQAGQDQP TLTTGPPAIKAQEPIWRAWAWLPHSQEMLTHGQ ETVETAPEPPASSRRDSLTISPGHVVEWGERPLP WVRLPALPSWRGALPLRP*AHCAWGSRLQPLAQ SQQPAKHTEGDCHLPLPAAEPQRSDGSYTGQGF LLGITSHRNQ*FVVIWICVLMSFTV*F*LLIVQA FPNKRGESQAGLGTALTLVPGASMGSLTDRTPA VPLEAVPRWLWNRNA

Sequence NM_181797

GCGGCGGGGCTGGCAGCAGTGGCTGCCCGCACTGCGCCCGGGCGCTCGCCTTCGCTGCAGCTCCCGGTGCCGCCGCTCGGGCCGGCCCCCCGGCAGGCCC TCCTCGTTATGGCCGCGGCCTCCTCCCCGCCCAGGGCCGAGAGGAAGCGCTGGGGTTGGGGCCGCCTGCCAGGCGCCCGGCGGGGCAGCGCGGGCCTGGC CAAGAAGTGCCCCTTCTCGCTGGAGCTGGCGGAGGGCGGCCCGGCGGGCGGCGCGCTCTACGCGCCCATCGCGCCCGGCGCCCCAGGTCCCGCGCCCCCT GCGTCCCCGGCCGCGCCCGCCGCGCCCCCAGTTGCCTCCGACCTTGGCCCGCGGCCGCCGGTGAGCCTAGACCCGCGCGTCTCCATCTACAGCACGCGCC GCCCGGTGTTGGCGCGCACCCACGTCCAGGGCCGCGTCTACAACTTCCTCGAGCGTCCCACCGGCTGGAAATGCTTCGTTTACCACTTCGCCGTATTCAA GAAATTAAGCATACGGTCACGAGAGTGCAAAGTTCTGTGAAACGCTCCAGTGGTTACACGCCCCGGGGTTTCAGCTTCGACCCTGGCTTCCTCATCGTCC TGGTCTGCCTCATCTTCAGCGTGCTGTCCACCATCGAGCAGTATGCCGCCCTGGCCACGGGGACTCTCTTCTGGATGGAGATCGTGCTGGTGGTGTTCTT CGGGACGGAGTACGTGGTCCGCCTCTGGTCCGCCGGCTGCCGCAGCAAGTACGTGGGCCTCTGGGGGCGGCTGCGCTTTGCCCGGAAGCCCATTTCCATC ATCGACCTCATCGTGGTCGTGGCCTCCATGGTGGTCCTCTGCGTGGGCTCCAAGGGGCAGGTGTTTGCCACGTCGGCCATCAGGGGCATCCGCTTCCTGC AGATCCTGAGGATGCTACACGTCGACCGCCAGGGAGGCACCTGGAGGCTCCTGGGCTCCGTGGTCTTCATCCACCGCCAGGAGCTGATAACCACCCTGTA CATCGGCTTCCTGGGCCTCATCTTCTCCTCGTACTTTGTGTACCTGGCTGAGAAGGACGCGGTGAACGAGTCAGGCCGCGTGGAGTTCGGCAGCTACGCA GATGCGCTGTGGTGGGGGGTGGTCACAGTCACCACCATCGGCTATGGGGACAAGGTGCCCCAGACGTGGGTCGGGAAGACCATCGCCTCCTGCTTCTCTG TCTTTGCCATCTCCTTCTTTGCGCTCCCAGCGGGGATTCTTGGCTCGGGGTTTGCCCTGAAGGTGCAGCAGAAGCAGAGGCAGAAGCACTTCAACCGGCA GATCCCGGCGGCAGCCTCACTCATTCAGACCGCATGGAGGTGCTATGCTGCCGAGAACCCCGACTCCTCCACCTGGAAGATCTACATCCGGAAGGCCCCC CGGAGCCACACTCTGCTGTCACCCAGCCCCAAACCCAAGAAGTCTGTGGTGGTAAAGAAAAAAAAGTTCAAGCTGGACAAAGACAATGGGGTGACTCCTG GAGAGAAGATGCTCACAGTCCCCCATATCACGTGCGACCCCCCAGAAGAGCGGCGGCTGGACCACTTCTCTGTCGACGGCTATGACAGTTCTGTAAGGAA GAGCCCAACACTGCTGGAAGTGAGCATGCCCCATTTCATGAGAACCAACAGCTTCGCCGAGGACCTGGACCTGGAAGGGGAGACTCTGCTGACACCCATC ACCCACATCTCACAGCTGCGGGAACACCATCGGGCCACCATTAAGGTCATTCGACGCATGCAGTACTTTGTGGCCAAGAAGAAATTCCAGCAAGCGCGGA AGCCTTACGATGTGCGGGACGTCATTGAGCAGTACTCGCAGGGCCACCTCAACCTCATGGTGCGCATCAAGGAGCTGCAGAGGAGGCTGGACCAGTCCAT TGGGAAGCCCTCACTGTTCATCTCCGTCTCAGAAAAGAGCAAGGATCGCGGCAGCAACACGATCGGCGCCCGCCTGAACCGAGTAGAAGACAAGGTGACG CAGCTGGACCAGAGGCTGGCACTCATCACCGACATGCTTCACCAGCTGCTCTCCTTGCACGGTGGCAGCACCCCCGGCAGCGGCGGCCCCCCCAGAGAGG GCGGGGCCCACATCACCCAGCCCTGCGGCAGTGGCGGCTCCGTCGACCCTGAGCTCTTCCTGCCCAGCAACACCCTGCCCACCTACGAGCAGCTGACCGT GCCCAGGAGGGGCCCCGATGAGGGGTCCTGAGGAGGGGATGGGGCTGGGGGATGGGCCTGAGTGAGAGGGGAGGCCAAGAGTGGCCCCACCTGGCCCTCT CTGAAGGAGGCCACCTCCTAAAAGGCCCAGAGAGAAGAGCCCCACTCTCAGAGGCCCCAATACCCCATGGACCATGCTGTCTGGCACAGCCTGCACTTGG GGGCTCAGCAAGGCCACCTCTTCCTGGCCGGTGTGGGGGCCCCGTCTCAGGTCTGAGTTGTTACCCCAAGCGCCCTGGCCCCCACATGGTGATGTTGACA TCACTGGCATGGTGGTTGGGACCCAGTGGCAGGGCACAGGGCCTGGCCCATGTATGGCCAGGAAGTAGCACAGGCTGAGTGCAGGCCCACCCTGCTTGGC CCAGGGGGCTTCCTGAGGGGAGACAGAGCAACCCCTGGACCCCAGCCTCAAATCCAGGACCCTGCCAGGCACAGGCAGGGCAGGACCAGCCCACGCTGAC TACAGGGCCGCCGGCAATAAAAGCCCAGGAGCCCATTTGGAGGGCCTGGGCCTGGCTCCCTCACTCTCAGGAAATGCTGACCCATGGGCAGGAGACTGTG GAGACTGCTCCTGAGCCCCCAGCTTCCAGCAGGAGGGACAGTCTCACCATTTCCCCAGGGCACGTGGTTGAGTGGGGGGAACGCCCACTTCCCTGGGTTA GACTGCCAGCTCTTCCTAGCTGGAGAGGAGCCCTGCCTCTCCGCCCCTGAGCCCACTGTGCGTGGGGCTCCCGCCTCCAACCCCTCGCCCAGTCCCAGCA GCCAGCCAAACACACAGAAGGGGACTGCCACCTCCCCTTGCCAGCTGCTGAGCCGCAGAGAAGTGACGGTTCCTACACAGGACAGGGGTTCCTTCTGGGC ATTACATCGCATAGAAATCAATAATTTGTGGTGATTTGGATCTGTGTTTTAATGAGTTTCACAGTGTGATTTTGATTATTAATTGTGCAAGCTTTTCCTA ATAAACGTGGAGAATCACAGGCTGGGCTGGGCACTGCTCTCACCTTGGTTCCTGGGGCATCCATGGGGTCTCTCACAGACAGGACCCCTGCAGTTCCCCT GGAAGCAGTGCCCAGGTGGCTGTGGAATAGGAACGCTA

refseq_KCNQ1.F1 (forward primer)
refseq_KCNQ1.R1 (reverse primer)
Single exon skipping

Frame 0

AAGLAAVAARTAPGRSPSLQLPVPPLGPAPRQA LLVMAAASSPPRAERKRWGWGRLPGARRGSAGLA KKCPFSLELAEGGPAGGALYAPIAPGAPGPAPP ASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTR RPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFK KLSIRSRECKVL*NAPVVTRPGVSASTLASSSS WSASSSACCPPSSSMPPWPRGLSSGWRSCWWCS SGRSTWSASGPPAAAASTWASGGGCALPGSPFPS STSSWSWPPWWSSAWAPRGRCLPRRPSGASASC RS*GCYTSTAREAPGGSWAPWSSSTARS**PPC TSASWASSSPRTLCTWLRRTR*TSQAAWSSAATQ MRCGGGWSQSPPSAMGTRCPRRGSGRPSPPASL SLPSPSLRSQRGFLARGLP*RCSRSRGRSTSTG RSRRQPHSFRPHGGAMLPRTPTPPPGRSTSGRPP GATLCCHPAPNPRSLWW*RKKSSSWTKTMG*LL ERRCSQSPISRATPQKSGGWTTSLSTAMTVL*G RAQHCWK*ACPIS*EPTASPRTWTWKGRLC*HPS PTSHSCGNTIGPPLRSFDACSTLWPRRNSSKRG SLTMCGTSLSSTRRATSTSWCASRSCRGGWTSP LGSPHCSSPSQKRARIAAATRSAPA*TE*KTR*R SWTRGWHSSPTCFTSCSPCTVAAPPAAAAPPER AGPTSPSPAAVAAPSTLSSSCPATPCPPTSS*P CPGGAPMRGPEEGMGLGDGPE*EGRPRVAPPGPL *RRPPPKRPREKSPTLRGPNTPWTMLSGTACTW GLSKATSSWPVWGPRLRSELLPQAPWPPHGDVD ITGMVVGTQWQGTGPGPCMARK*HRLSAGPPCLA QGAS*GETEQPLDPSLKSRTLPGTGRAGPAHAD YRAAGNKSPGAHLEGLGLAPSLSGNADPWAGDC GDCS*APSFQQEGQSHHFPRARG*VGGTPTSLG* TASSS*LERSPASPPLSPLCVGLPPPTPRPVPA ASQTHRRGLPPPLASC*AAEK*RFLHRTGVPSG HYIA*KSIICGDLDLCFNEFHSVILIINCASFS* *TWRITGWAGHCSHLGSWGIHGVSHRQDPCSSP GSSAQVAVE*ER

Frame 1

RRGWQQWLPALRPGARLRCSSRCRRSGRPPGRP SSLWPRPPPRPGPRGSAGVGAACQAPGGAARAW PRSAPSRWSWRRAARRAARSTRPSRPAPQVPRPL RPRPRPPRPQLPPTLARGRR*A*TRASPSTARA ARCWRAPTSRAASTTSSSVPPAGNASFTTSPYS RN*AYGHESAKFCETLQWLHAPGFQLRPWLPHRP GLPHLQRAVHHRAVCRPGHGDSLLDGDRAGGVL RDGVRGPPLVRRLPQQVRGPLGAAALCPEAHFH HRPHRGRGLHGGPLRGLQGAGVCHVGHQGHPLPA DPEDATRRPPGRHLEAPGLRGLHPPPGADNHPV HRLPGPHLLLVLCVPG*EGRGERVRPRGVRQLR RCAVVGGGHSHHHRLWGQGAPDVGREDHRLLLLC LCHLLLCAPSGDSWLGVCPEGAAEAEAEALQPA DPGGSLTHSDRMEVLCCREPRLLHLEDLHPEGP PEPHSAVTQPQTQEVCGGKEKKVQAGQRQWGDSW REDAHSPPYHVRPPRRAAAGPLLCRRL*QFCKE EPNTAGSEHAPFHENQQLRRGPGPGRGDSADTH HPHLTAAGTPSGHH*GHSTHAVLCGQEEIPASAE ALRCAGRH*AVLAGPPQPHGAHQGAAEEAGPVH WEALTVHLRLRKEQGSRQQHDRRPPEPSRRQGD AAGPEAGTHHRHASPAALLARWQHPRQRRPPQRG RGPHHPALRQWRLRRP*ALPAQQHPAHLRAADR AQEGPR*GVLRRGWGWGMGLSERGGQEWPHLAL SEGGHLLKGPERRAPLSEAPIPHGPCCLAQPALG GSARPPLPGRCGGPVSGLSCYPKRPGPHMVMLT SLAWWLGPSGRAQGLAHVWPGSSTG*VQAHPAW PRGLPEGRQSNPWTPASNPGPCQAQAGQDQPTLT TGPPAIKAQEPIWRAWAWLPHSQEMLTHGQETV ETAPEPPASSRRDSLTISPGHVVEWGERPLPWV RLPALPSWRGALPLRP*AHCAWGSRLQPLAQSQQ PAKHTEGDCHLPLPAAEPQRSDGSYTGQGFLLG ITSHRNQ*FVVIWICVLMSFTV*F*LLIVQAFP NKRGESQAGLGTALTLVPGASMGSLTDRTPAVPL EAVPRWLWNRNA

Frame 2

GGAGSSGCPHCARALAFAAAPGAAARAGPPAGP PRYGRGLLPAQGREEALGLGPPARRPAGQRGPG QEVPLLAGAGGGRPGGRRALRAHRARRPRSRAP CVPGRARRAPSCLRPWPAAAGEPRPARLHLQHAP PGVGAHPRPGPRLQLPRASHRLEMLRLPLRRIQ EIKHTVTRVQSSVKRSSGYTPRGFSFDPGFLIV LVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFF GTEYVVRLWSAGCRSKYVGLWGRLRFARKPISI IDLIVVVASMVVLCVGSKGQVFATSAIRGIRFL QILRMLHVDRQGGTWRLLGSVVFIHRQELITTLY IGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYA DALWWGVVTVTTIGYGDKVPQTWVGKTIASCFS VFAISFFALPAGILGSGFALKVQQKQRQKHFNRQ IPAAASLIQTAWRCYAAENPDSSTWKIYIRKAP RSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTP GEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRK SPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPI THISQLREHHRATIKVIRRMQYFVAKKKFQQAR KPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSI GKPSLFISVSEKSKDRGSNTIGARLNRVEDKVT QLDQRLALITDMLHQLLSLHGGSTPGSGGPPRE GGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTV PRRGPDEGS*GGDGAGGWA*VRGEAKSGPTWPS LKEATS*KAQREEPHSQRPQYPMDHAVWHSLHL GAQQGHLFLAGVGAPSQV*VVTPSALAPTW*C*H HWHGGWDPVAGHRAWPMYGQEVAQAECRPTLLG PGGFLRGDRATPGPQPQIQDPARHRQGRTSPR* LQGRRQ*KPRSPFGGPGPGSLTLRKC*PMGRRLW RLLLSPQLPAGGTVSPFPQGTWLSGGNAHFPGL DCQLFLAGEEPCLSAPEPTVRGAPASNPSPSPS SQPNTQKGTATSPCQLLSRREVTVPTQDRGSFWA LHRIEINNLW*FGSVF**VSQCDFDY*LCKLFL INVENHRLGWALLSPWFLGHPWGLSQTGPLQFP WKQCPGGCGIGTL