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Sequences

Sequence NM_017490

TCCTGGAATTGCACGCGCTTCCTGACCACCAGGCTCTGGCCCTTGAGAAGCCAGCGGGGCTTTGTCCCTGTTGCTCTCCTTGCCAAACCCAGTCTCTCTG CTAGTGGTGGTTTCGGTTGCGACACCGTCCAGGTTCCCAGGCAGGAACCGCTCGGCCTGGCTGCTTAGCTACTTTTCACTGAGGAGGTGGTGGAAGGTGT CGCCTGCTCTGGCTGAGTAAGGGTGGCTGGCTGAGCCGGCAGCCCCCGCCCTAGGCCTGGCTCTTCCCGGCCTCTGTACTTTGCCCTCGCTGCCTGACAG GTTCTGCTGTGGGCTCTGCTGAATGGAAGTCGCTGGTAGTCCTTTTCCCTTTCTCCAGTCGGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAA GTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTT GCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTAT TCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTA CGCTAGTGGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAG TACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCA ATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGT GGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGG GGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAA TCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCT GATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAG AGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCA GCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGC AGAAAATAAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAG ACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCA TCCAGAATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTTCTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCACCAGAA ATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTAACTGTGAGGTGCCGCGGCCCAGCACAGCCCCCCAGCGTGTC CCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATG CTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGG GAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGC AGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCA ACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGG CCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCC TTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCC GCTGCGCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCCCACAT TCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCCTCGGTACTGCGGTT GCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAGAAAAAA

refseq_MARK2.F2 (forward primer)
refseq_MARK2.R2 (reverse primer)
Single exon skipping

Frame 0

SWNCTRFLTTRLWPLRSQRGFVPVALLAKPSLS ASGGFGCDTVQVPRQEPLGLAA*LLFTEEVVEGV ACSG*VRVAG*AGSPRPRPGSSRPLYFALAA*Q VLLWALLNGSRW*SFSLSPVGPPWDTLTPSPAV SPT*FGAATQPPLLMSSPTLETTGSSRPLARVIL PR*SWPDTS*LGKR*L*RSLTRLN*TPPASRNY SAK*E**RF*IIPT*LNYLK*LRLRKRSTLSWS TLVAERYLIT*WLMAG*KKKRLEPNSAR*CLLCS TVTRSLLSIET*RQKTCSWMLI*TSRLQTLASA MNSPLGTSWTPSVAVPLMLPQNSSRAKNMMDPR WMCGA*ELSSIHWSADPCLLMDRTSRSCGNGY*G ENTVFHSTCPRTVKTCLRNFSFLIPAREAL*SK S*KIDG*MWVTKMMN*SLTWSHSLTTRTPGGQS *WCPWVIHGKRSRTRWWARDTTR*WPPICSWATR APSWKATPSP*NPGLQLI*PIAAPHPHPTRYSA ACRPIPSSGASATRLVLPFPPLILTLRRLRVTT QKISGLRRTGSQGGKPAAQPRCLPAPCPVWRGRR PPQPPPRTASSPPAQIEAGIPHFWSGPASARPP SRMAKTA*PCQGPGPPRLLLLPQSLRPGPASTR NPCRPPCTPTRPLGCPPRRVTVRCRGPAQPPSVS LLPPHPPTTSAAVVEPQTELTSPGVCPAEAPSM LGSSDRCGTSRICPTV*PQPLPLATARAGGGPL GASSASSPPSLYAGT*MNLKAKTEWRRSDLTWWA VAATTKKRKNFGRPSPAPSASRGV*RPRAPWSP TR*CGRSARCWTRTAARASCMRSTCCCACTARR ATRTSCSGRWRCANCRGSLSTGFDLSGYRAPPWP SKTLPPK*PTS*SFNRLPGAGAAGAGQLDGLPA AAPPHLGETAAMDWCVSPAGTSPLPGPSQFSPT FTPAQRFPLLLSPTGGKGRGGWMGGQGSPSVLRL HRVFRLNQEIFYYQKEK

Frame 1

PGIARAS*PPGSGP*EASGALSLLLSLPNPVSL LVVVSVATPSRFPGRNRSAWLLSYFSLRRWWKV SPALAE*GWLAEPAAPALGLALPGLCTLPSLPDR FCCGLC*MEVAGSPFPFLQSAHLGTP*LQAQQ* VQHDSGPQLSHLC**AAPHWKLPAPQDHWQG*F CQGEVGPTHPDWERGSCEDH*QDSTELLQPPETI PRSKNNEGFESSQHS*II*SD*D*ENALPCHGV R*WRRGI*LPSGSWQDERKRGSSQIPPDSVCCA VLSPEVYCP*RLKGRKPALGC*YEHQDCRLWLQQ *IHLWEQAGHLLWQSPLCCPRTLPGQKI*WTRG GCVEPRSYPLYTGQRIPAF*WTEPQGAAGTGTE GKIPYSILHVHGL*KPA*EISHS*SQQERHFRAN HERSMDECGSRR**TKALRGATP*LQGPPADRA DGVHGLYTGRDPGLAGGPEIQRGDGHLSAPGLQ ELRAGRRHHHPETPAFS*SDQ*QRPIPIPQGTAQ RVGQSQAAALQRPGWSCHSHL*FLL*EDSE*QR RK*AA*GGPGVRAESQQHSQGACQPPARSGEEE DHPNPLHEQRPLHQHKSKQEFPTFGAGQPRPGLH PEWQRQPNHARVPGLHGFCFCRSLCGPAPPAPE IHVGLRAPQQGLWAAPHGE*L*GAAAQHSPPAC PCCLPIRPQHQQQWWSPRPN*LPPGCVQPKHLPC WAAPTGAGPAEFALRCDPSLSLWPQPGPAGGLW EHLQQVHLQVCTQEPE*T*KQRPSGDAQTSRGG QWRQRQRKGRISGGQAPLPPLHVEYEDHELHGAQ RDDAGDPQGAGREQLPERAA*EVHAAVHARHAG PRGLRAVGDGGVQTAAALSQRGSI*ADIGHLHG LQKHCLQNSQRAEALTGCQERGRRGRASWTGCRP LRRPTWARLQRWIGVSPLLALLPSLALLSFLPH SPLPRDSPFSSPLLEAKEGEGGWGGRAPPRYCG CTEYFA*TKKFFITKKKK

Frame 2

LELHALPDHQALALEKPAGLCPCCSPCQTQSLC *WWFRLRHRPGSQAGTARPGCLATFH*GGGGRC RLLWLSKGGWLSRQPPP*AWLFPASVLCPRCLT GSAVGSAEWKSLVVLFPFSSRPTLGHLDSKPSSK SNMIRGRNSATSADEQPHIGNYRLLKTIGKGNF AKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEY ASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ YCHQKFIVHRDLKAENLLLDADMNIKIADFGFS NEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV DVWSLGVILYTLVSGSLPFDGQNLKELRERVLR GKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTEL MVSMGYTREEIQDSLVGQRYNEVMATYLLLGYK SSELEGDTITLKPRPSADLTNSSAPSPSHKVQR SVSANPKQRRFSDQAGPAIPTSNSYSKKTQSNNA ENKRPEEDRESGRKASSTAKVPASPLPGLERKK TTPTPSTNSVLSTSTNRSRNSPLLERASLGQAS IQNGKDSLTMPGSRASTASASAAVSAARPRQHQK SMSASVHPNKASGLPPTESNCEVPRPSTAPQRV PVASPSAHNISSSGGAPDRTNFPRGVSSRSTFH AGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASG SIFSKFTSKFVRRNLNEPESKDRVETLRPHVVG SGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEP NEMMREIRKVLDANSCQSELHEKYMLLCMHGTPG HEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMA FKNIASKIANELKL*QAARSGGGGGGPAGRAAG RCAAPPGRDCSDGLVCLPCWHFSPPWPFSVFSHI HPCPEIPPSPLPYWRQRKGRVDGGAGLPLGTAV AQSISPKPRNFLLPKRK

Sequence NM_004954

TCCTGGAATTGCACGCGCTTCCTGACCACCAGGCTCTGGCCCTTGAGAAGCCAGCGGGGCTTTGTCCCTGTTGCTCTCCTTGCCAAACCCAGTCTCTCTG CTAGTGGTGGTTTCGGTTGCGACACCGTCCAGGTTCCCAGGCAGGAACCGCTCGGCCTGGCTGCTTAGCTACTTTTCACTGAGGAGGTGGTGGAAGGTGT CGCCTGCTCTGGCTGAGTAAGGGTGGCTGGCTGAGCCGGCAGCCCCCGCCCTAGGCCTGGCTCTTCCCGGCCTCTGTACTTTGCCCTCGCTGCCTGACAG GTTCTGCTGTGGGCTCTGCTGAATGGAAGTCGCTGGTAGTCCTTTTCCCTTTCTCCAGTCGGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAA GTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTT GCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTAT TCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTA CGCTAGTGGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAG TACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCA ATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGT GGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGG GGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAA TCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCT GATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAG AGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCA GCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGC AGAAAATAAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAG ACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCA TCCAGAATGGCAAAGACAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAA CTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCT CCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGGAACCTGAATGAACCTGAAAGCA AAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTT CACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCAT GAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACG GGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGG GGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTCCCCTGCTGGCAC TTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGG TGGATGGGGGGGCAGGGCTCCCCCTCGGTACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAGAAAAAA

refseq_MARK2.F2 (forward primer)
refseq_MARK2.R2 (reverse primer)
Single exon skipping

Frame 0

SWNCTRFLTTRLWPLRSQRGFVPVALLAKPSLS ASGGFGCDTVQVPRQEPLGLAA*LLFTEEVVEGV ACSG*VRVAG*AGSPRPRPGSSRPLYFALAA*Q VLLWALLNGSRW*SFSLSPVGPPWDTLTPSPAV SPT*FGAATQPPLLMSSPTLETTGSSRPLARVIL PR*SWPDTS*LGKR*L*RSLTRLN*TPPASRNY SAK*E**RF*IIPT*LNYLK*LRLRKRSTLSWS TLVAERYLIT*WLMAG*KKKRLEPNSAR*CLLCS TVTRSLLSIET*RQKTCSWMLI*TSRLQTLASA MNSPLGTSWTPSVAVPLMLPQNSSRAKNMMDPR WMCGA*ELSSIHWSADPCLLMDRTSRSCGNGY*G ENTVFHSTCPRTVKTCLRNFSFLIPAREAL*SK S*KIDG*MWVTKMMN*SLTWSHSLTTRTPGGQS *WCPWVIHGKRSRTRWWARDTTR*WPPICSWATR APSWKATPSP*NPGLQLI*PIAAPHPHPTRYSA ACRPIPSSGASATRLVLPFPPLILTLRRLRVTT QKISGLRRTGSQGGKPAAQPRCLPAPCPVWRGRR PPQPPPRTASSPPAQIEAGIPHFWSGPASARPP SRMAKTAQPPSVSLLPPHPPTTSAAVVEPQTEL TSPGVCPAEAPSMLGSSDRCGTSRICPTV*PQPL PLATARAGGGPLGASSASSPPSLYAGT*MNLKA KTEWRRSDLTWWAVAATTKKRKNFGRPSPAPSA SRGV*RPRAPWSPTR*CGRSARCWTRTAARASCM RSTCCCACTARRATRTSCSGRWRCANCRGSLST GFDLSGYRAPPWPSKTLPPK*PTS*SFNRLPGA GAAGAGQLDGLPAAAPPHLGETAAMDWCVSPAGT SPLPGPSQFSPTFTPAQRFPLLLSPTGGKGRGG WMGGQGSPSVLRLHRVFRLNQEIFYYQKEK

Frame 1

PGIARAS*PPGSGP*EASGALSLLLSLPNPVSL LVVVSVATPSRFPGRNRSAWLLSYFSLRRWWKV SPALAE*GWLAEPAAPALGLALPGLCTLPSLPDR FCCGLC*MEVAGSPFPFLQSAHLGTP*LQAQQ* VQHDSGPQLSHLC**AAPHWKLPAPQDHWQG*F CQGEVGPTHPDWERGSCEDH*QDSTELLQPPETI PRSKNNEGFESSQHS*II*SD*D*ENALPCHGV R*WRRGI*LPSGSWQDERKRGSSQIPPDSVCCA VLSPEVYCP*RLKGRKPALGC*YEHQDCRLWLQQ *IHLWEQAGHLLWQSPLCCPRTLPGQKI*WTRG GCVEPRSYPLYTGQRIPAF*WTEPQGAAGTGTE GKIPYSILHVHGL*KPA*EISHS*SQQERHFRAN HERSMDECGSRR**TKALRGATP*LQGPPADRA DGVHGLYTGRDPGLAGGPEIQRGDGHLSAPGLQ ELRAGRRHHHPETPAFS*SDQ*QRPIPIPQGTAQ RVGQSQAAALQRPGWSCHSHL*FLL*EDSE*QR RK*AA*GGPGVRAESQQHSQGACQPPARSGEEE DHPNPLHEQRPLHQHKSKQEFPTFGAGQPRPGLH PEWQRQHSPPACPCCLPIRPQHQQQWWSPRPN* LPPGCVQPKHLPCWAAPTGAGPAEFALRCDPSL SLWPQPGPAGGLWEHLQQVHLQVCTQEPE*T*KQ RPSGDAQTSRGGQWRQRQRKGRISGGQAPLPPL HVEYEDHELHGAQRDDAGDPQGAGREQLPERAA *EVHAAVHARHAGPRGLRAVGDGGVQTAAALSQR GSI*ADIGHLHGLQKHCLQNSQRAEALTGCQER GRRGRASWTGCRPLRRPTWARLQRWIGVSPLLA LLPSLALLSFLPHSPLPRDSPFSSPLLEAKEGEG GWGGRAPPRYCGCTEYFA*TKKFFITKKKK

Frame 2

LELHALPDHQALALEKPAGLCPCCSPCQTQSLC *WWFRLRHRPGSQAGTARPGCLATFH*GGGGRC RLLWLSKGGWLSRQPPP*AWLFPASVLCPRCLT GSAVGSAEWKSLVVLFPFSSRPTLGHLDSKPSSK SNMIRGRNSATSADEQPHIGNYRLLKTIGKGNF AKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEY ASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ YCHQKFIVHRDLKAENLLLDADMNIKIADFGFS NEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV DVWSLGVILYTLVSGSLPFDGQNLKELRERVLR GKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTEL MVSMGYTREEIQDSLVGQRYNEVMATYLLLGYK SSELEGDTITLKPRPSADLTNSSAPSPSHKVQR SVSANPKQRRFSDQAGPAIPTSNSYSKKTQSNNA ENKRPEEDRESGRKASSTAKVPASPLPGLERKK TTPTPSTNSVLSTSTNRSRNSPLLERASLGQAS IQNGKDSTAPQRVPVASPSAHNISSSGGAPDRTN FPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPAS PSGHSQGRRGASGSIFSKFTSKFVRRNLNEPES KDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRF TWSMKTTSSMEPNEMMREIRKVLDANSCQSELH EKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLN GVRFKRISGTSMAFKNIASKIANELKL*QAARSG GGGGGPAGRAAGRCAAPPGRDCSDGLVCLPCWH FSPPWPFSVFSHIHPCPEIPPSPLPYWRQRKGR VDGGAGLPLGTAVAQSISPKPRNFLLPKRK

Sequence NM_001039468

AAGCCCCGCCCGGCCGGGCTCCGCGCCTTCCCTTCCCTCCCTTCCTCCAAGCTTCTCGGTTCCCTCCCCCGAGATACCGGCGCCATGTCCAGCGCTCGGA CCCCCCTACCCACGCTGAACGAGAGGGACACGGAGCAGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAA CTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACAC ATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGG TTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGA TTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTTATTGTC CATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTCACCTTTGGGAACAAGC TGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTAT CCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTAC ATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATG TGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACG GGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACC ATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGC GGCGCTTCAGCGACCAGGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGA CCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCCTCCACGAAC AGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAGAATGGCAAAGACAGCACAG CCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGTGTGTCCAGCCG AAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGG CGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGAC CTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAG CTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATG CACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGG GCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGG ACGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCA GTTTTCTCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCC TCGGTACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAGAAAAAA

refseq_MARK2.F2 (forward primer)
refseq_MARK2.R2 (reverse primer)
Single exon skipping

Frame 0

KPRPAGLRAFPSLPSSKLLGSLPRDTGAMSSAR TPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRN SATSADEQPHIGNYRLLKTIGKGNFAKVKLARH ILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMK VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFD YLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIV HRDLKAENLLLDADMNIKIADFGFSNEFTFGNK LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY MSTDCENLLKKFLILNPSKRGTLEQIMKDRWMN VGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTR EEIQDSLVGQRYNEVMATYLLLGYKSSELEGDT ITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQ RRFSDQAGPAIPTSNSYSKKTQSNNAENKRPEED RESGRKASSTAKVPASPLPGLERKKTTPTPSTN SVLSTSTNRSRNSPLLERASLGQASIQNGKDST APQRVPVASPSAHNISSSGGAPDRTNFPRGVSSR STFHAGQLRQVRDQQNLPYGVTPASPSGHSQGR RGASGSIFSKFTSKFVRRNLNEPESKDRVETLR PHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTS SMEPNEMMREIRKVLDANSCQSELHEKYMLLCM HGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRIS GTSMAFKNIASKIANELKL*QAARSGGGGGGPAG RAAGRCAAPPGRDCSDGLVCLPCWHFSPPWPFS VFSHIHPCPEIPPSPLPYWRQRKGRVDGGAGLP LGTAVAQSISPKPRNFLLPKRK

Frame 1

SPARPGSAPSLPSLPPSFSVPSPEIPAPCPALG PPYPR*TRGTRSSPPWDTLTPSPAVSPT*FGAA TQPPLLMSSPTLETTGSSRPLARVILPR*SWPDT S*LGKR*L*RSLTRLN*TPPASRNYSAK*E**R F*IIPT*LNYLK*LRLRKRSTLSWSTLVAERYL IT*WLMAG*KKKRLEPNSAR*CLLCSTVTRSLLS IET*RQKTCSWMLI*TSRLQTLASAMNSPLGTS WTPSVAVPLMLPQNSSRAKNMMDPRWMCGA*EL SSIHWSADPCLLMDRTSRSCGNGY*GENTVFHST CPRTVKTCLRNFSFLIPAREAL*SKS*KIDG*M WVTKMMN*SLTWSHSLTTRTPGGQS*WCPWVIH GKRSRTRWWARDTTR*WPPICSWATRAPSWKATP SP*NPGLQLI*PIAAPHPHPTRYSAACRPIPSS GASATRLVLPFPPLILTLRRLRVTTQKISGLRR TGSQGGKPAAQPRCLPAPCPVWRGRRPPQPPPRT ASSPPAQIEAGIPHFWSGPASARPPSRMAKTAQ PPSVSLLPPHPPTTSAAVVEPQTELTSPGVCPA EAPSMLGSSDRCGTSRICPTV*PQPLPLATARAG GGPLGASSASSPPSLYAGT*MNLKAKTEWRRSD LTWWAVAATTKKRKNFGRPSPAPSASRGV*RPR APWSPTR*CGRSARCWTRTAARASCMRSTCCCAC TARRATRTSCSGRWRCANCRGSLSTGFDLSGYR APPWPSKTLPPK*PTS*SFNRLPGAGAAGAGQL DGLPAAAPPHLGETAAMDWCVSPAGTSPLPGPSQ FSPTFTPAQRFPLLLSPTGGKGRGGWMGGQGSP SVLRLHRVFRLNQEIFYYQKEK

Frame 2

APPGRAPRLPFPPFLQASRFPPPRYRRHVQRSD PPTHAEREGHGAAHLGTP*LQAQQ*VQHDSGPQ LSHLC**AAPHWKLPAPQDHWQG*FCQGEVGPT HPDWERGSCEDH*QDSTELLQPPETIPRSKNNEG FESSQHS*II*SD*D*ENALPCHGVR*WRRGI* LPSGSWQDERKRGSSQIPPDSVCCAVLSPEVYC P*RLKGRKPALGC*YEHQDCRLWLQQ*IHLWEQA GHLLWQSPLCCPRTLPGQKI*WTRGGCVEPRSY PLYTGQRIPAF*WTEPQGAAGTGTEGKIPYSIL HVHGL*KPA*EISHS*SQQERHFRANHERSMDEC GSRR**TKALRGATP*LQGPPADRADGVHGLYT GRDPGLAGGPEIQRGDGHLSAPGLQELRAGRRH HHPETPAFS*SDQ*QRPIPIPQGTAQRVGQSQAA ALQRPGWSCHSHL*FLL*EDSE*QRRK*AA*GG PGVRAESQQHSQGACQPPARSGEEEDHPNPLHE QRPLHQHKSKQEFPTFGAGQPRPGLHPEWQRQHS PPACPCCLPIRPQHQQQWWSPRPN*LPPGCVQP KHLPCWAAPTGAGPAEFALRCDPSLSLWPQPGP AGGLWEHLQQVHLQVCTQEPE*T*KQRPSGDAQT SRGGQWRQRQRKGRISGGQAPLPPLHVEYEDHE LHGAQRDDAGDPQGAGREQLPERAA*EVHAAVH ARHAGPRGLRAVGDGGVQTAAALSQRGSI*ADIG HLHGLQKHCLQNSQRAEALTGCQERGRRGRASW TGCRPLRRPTWARLQRWIGVSPLLALLPSLALL SFLPHSPLPRDSPFSSPLLEAKEGEGGWGGRAPP RYCGCTEYFA*TKKFFITKKKK

Sequence NM_001039469

CCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAA ACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGA CAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTG ATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGG CTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGC TGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCA GAACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATG GACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCT CATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAG CCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACA ACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAA TAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCAGCTGGTCCTGCCATTCCC ACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCA AGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAA TTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAGAATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCT TCTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCACCAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTA ACTGTGAGGTGCCGCGGCCCAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAAC TAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCC TCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGGTTTG CCAGAAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATT TCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTG GACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGG TGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGA GCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGC GATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCTTACATGTTTGTGGGGGGTGGGAGATTGTTCTCCAGCA CCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCCTCGGTA CTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAA

refseq_MARK2.F2 (forward primer)
refseq_MARK2.R2 (reverse primer)
Single exon skipping

Frame 0

PTLGHLDSKPSSKSNMIRGRNSATSADEQPHIG NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIID KTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEV IETEKTLYLVMEYASGGEVFDYLVAHGRMKEKE ARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDA DMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAP ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD GQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL ILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVE PLPDYKDPRRTELMVSMGYTREEIQDSLVGQRY NEVMATYLLLGYKSSELEGDTITLKPRPSADLTN SSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIP TSNSYSKKTQSNNAENKRPEEDRESGRKASSTA KVPASPLPGLERKKTTPTPSTNSVLSTSTNRSRN SPLLERASLGQASIQNGKDSLTMPGSRASTASA SAAVSAARPRQHQKSMSASVHPNKASGLPPTES NCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRT NFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPA SPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRF ARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEF REAKPRSLRFTWSMKTTSSMEPNEMMREIRKVL DANSCQSELHEKYMLLCMHGTPGHEDFVQWEME VCKLPRLSLNGVRFKRISGTSMAFKNIASKIANE LKL*QAARSGGGGGGPAGRAAGRCAAPPGRDCS DGLVCLPCWHFSPPWPFSVFSYMFVGGGRLFSS TPHSPLPRDSPFSSPLLEAKEGEGGWGGRAPPRY CGCTEYFA*TKKFFITK

Frame 1

PPWDTLTPSPAVSPT*FGAATQPPLLMSSPTLE TTGSSRPLARVILPR*SWPDTS*LGKR*L*RSL TRLN*TPPASRNYSAK*E**RF*IIPT*LNYLK* LRLRKRSTLSWSTLVAERYLIT*WLMAG*KKKR LEPNSAR*CLLCSTVTRSLLSIET*RQKTCSWM LI*TSRLQTLASAMNSPLGTSWTPSVAVPLMLPQ NSSRAKNMMDPRWMCGA*ELSSIHWSADPCLLM DRTSRSCGNGY*GENTVFHSTCPRTVKTCLRNF SFLIPAREAL*SKS*KIDG*MWVTKMMN*SLTWS HSLTTRTPGGQS*WCPWVIHGKRSRTRWWARDT TR*WPPICSWATRAPSWKATPSP*NPGLQLI*P IAAPHPHPTRYSAACRPIPSSGASATRQLVLPFP PLILTLRRLRVTTQKISGLRRTGSQGGKPAAQP RCLPAPCPVWRGRRPPQPPPRTASSPPAQIEAG IPHFWSGPASARPPSRMAKTA*PCQGPGPPRLLL LPQSLRPGPASTRNPCRPPCTPTRPLGCPPRRV TVRCRGPAQPPSVSLLPPHPPTTSAAVVEPQTE LTSPGVCPAEAPSMLGSSDRCGTSRICPTV*PQP LPLATARAGGGPLGASSASSPPSLYAEICLSGL PEGT*MNLKAKTEWRRSDLTWWAVAATTKKRKN FGRPSPAPSASRGV*RPRAPWSPTR*CGRSARCW TRTAARASCMRSTCCCACTARRATRTSCSGRWR CANCRGSLSTGFDLSGYRAPPWPSKTLPPK*PT S*SFNRLPGAGAAGAGQLDGLPAAAPPHLGETAA MDWCVSPAGTSPLPGPSQFSLTCLWGVGDCSPA PHIHPCPEIPPSPLPYWRQRKGRVDGGAGLPLG TAVAQSISPKPRNFLLPK

Frame 2

HLGTP*LQAQQ*VQHDSGPQLSHLC**AAPHWK LPAPQDHWQG*FCQGEVGPTHPDWERGSCEDH* QDSTELLQPPETIPRSKNNEGFESSQHS*II*S D*D*ENALPCHGVR*WRRGI*LPSGSWQDERKRG SSQIPPDSVCCAVLSPEVYCP*RLKGRKPALGC *YEHQDCRLWLQQ*IHLWEQAGHLLWQSPLCCP RTLPGQKI*WTRGGCVEPRSYPLYTGQRIPAF*W TEPQGAAGTGTEGKIPYSILHVHGL*KPA*EIS HS*SQQERHFRANHERSMDECGSRR**TKALRG ATP*LQGPPADRADGVHGLYTGRDPGLAGGPEIQ RGDGHLSAPGLQELRAGRRHHHPETPAFS*SDQ *QRPIPIPQGTAQRVGQSQAAALQRPGSWSCHS HL*FLL*EDSE*QRRK*AA*GGPGVRAESQQHSQ GACQPPARSGEEEDHPNPLHEQRPLHQHKSKQE FPTFGAGQPRPGLHPEWQRQPNHARVPGLHGFC FCRSLCGPAPPAPEIHVGLRAPQQGLWAAPHGE* L*GAAAQHSPPACPCCLPIRPQHQQQWWSPRPN *LPPGCVQPKHLPCWAAPTGAGPAEFALRCDPS LSLWPQPGPAGGLWEHLQQVHLQVCTQKSVFQVC QKEPE*T*KQRPSGDAQTSRGGQWRQRQRKGRI SGGQAPLPPLHVEYEDHELHGAQRDDAGDPQGA GREQLPERAA*EVHAAVHARHAGPRGLRAVGDGG VQTAAALSQRGSI*ADIGHLHGLQKHCLQNSQR AEALTGCQERGRRGRASWTGCRPLRRPTWARLQ RWIGVSPLLALLPSLALLSFLLHVCGGWEIVLQH PTFTPAQRFPLLLSPTGGKGRGGWMGGQGSPSV LRLHRVFRLNQEIFYYQK