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Sequences

Sequence NM_201569

GAGGAGCCGGAGGAGAGGAAGATGGCGGCGGCCGCCAGCACCCGCGGTGCCGCGGGGCCGCTCCGAGGAGCCTGAGAGACCCACGGAGGCTTCGCGGGAA GACGCGGCGGCGGCGGCGGAGGATGAGCCTGCAGAGCGCGCAGTACCTCCGATTCTAAGCTGGGTCCAGCTGAAGTCTGGACATCCAGGCAGGCTCTGCA GGACCTGTACCAGAAAATGCTAGTTACCGATTTGGAATACGCTTTAGACAAGAAAGTAGAACAGGATCTCTGGAATCACGCCTTTAAGAATCAGATCACA ACACTGCAAGGCCAGGCAAAGAATCGAGCAAATCCGAATCGGAGTGAAGTTCAGGCAAACCTTTCTCTGTTCCTAGAGGCAGCTAGTGGCTTCTATACTC AGTTATTACAAGAACTGTGTACAGTATTTAATGTAGATTTACCATGCCGTGTGAAGTCTTCCCAATTGGGAATTATCAGCAATAAACAGACGCATACCAG CGCCATAGTGAAGCCACAGTCTAGCTCCTGTTCCTATATCTGCCAGCACTGCCTCGTCCACCTTGGAGACATTGCTCGATACAGAAACCAGACCAGCCAG GCAGAGTCCTACTATAGGCATGCAGCTCAGCTTGTCCCCTCCAATGGTCAGCCTTATAATCAGTTGGCTATCTTAGCTTCTTCCAAAGGAGACCATCTGA CCACAATTTTCTACTACTGCAGAAGCATTGCTGTGAAGTTCCCTTTCCCAGCTGCCTCCACTAATCTGCAAAAAGCACTTTCTAAAGCACTGGAAAGCCG AGATGAGGTGAAAACCAAGTGGGGTGTTTCTGACTTCATCAAGGCCTTTATTAAATTCCACGGTCATGTGTACCTGAGTAAGAGCTTGGAAAAGTTGAGC CCTCTTCGAGAGAAATTGGAAGAACAGTTTAAGAGGCTGCTATTCCAAAAAGCTTTCAACTCTCAGCAGTTAGTTCATGTCACTGTCATTAACCTGTTTC AACTTCATCACCTTCGTGACTTTAGCAATGAAACCGAGCAGCACACTTATAGCCAAGATGAGCAGCTATGTTGGACACAGTTGCTGGCCCTCTTTATGTC TTTTCTTGGCATCCTGTGCAAGTGTCCTCTACAGAATGAGTCTCAGGAGGAGTCCTACAATGCCTATCCTCTTCCAGCAGTCAAGGTCTCCATGGACTGG CTAAGACTCAGACCCAGGGTCTTTCAGGAGGCAGTGGTGGATGAAAGACAGTACATTTGGCCCTGGTTGATTTCTCTTCTGAATAGTTTCCATCCCCATG AAGAGGACCTCTCAAGTATTAGTGCGACACCACTTCCAGAGGAGTTTGAATTACAAGGATTTTTGGCATTGAGACCTTCTTTCAGGAACTTGGATTTTTC CAAAGGTCACCAGGGTATTACAGGGGACAAAGAAGGCCAGCAACGACGAATACGACAGCAACGCTTGATCTCTATAGGCAAATGGATTGCTGATAATCAG CCAAGGCTGATTCAGTGTGAAAATGAGGTAGGGAAATTGTTGTTTATCACAGAAATCCCAGAATTAATACTGGAAGACCCCAGTGAAGCCAAAGAGAACC TCATTCTGCAAGAAACATCTGTGATAGAGTCGCTGGCTGCAGATGGGAGCCCAGGGCTAAAATCAGTGCTATCTACAAGCCGAAATTTAAGCAACAACTG TGACACAGGAGAGAAGCCAGTGGTTACCTTCAAAGAAAACATTAAGACACGAGAAGTGAACAGAGACCAAGGAAGAAGTTTTCCTCCCAAAGAGGTAAAA TCCCAGACAGAACTAAGAAAGACTCCAGTGTCTGAAGCCAGAAAAACACCTGTAACTCAAACCCCAACTCAAGCAAGTAACTCCCAGTTCATCCCCATTC ATCACCCTGGAGCCTTCCCTCCTCTTCCCAGCAGGCCAGGGTTTCCGCCCCCAACATATGTTATCCCCCCGCCTGTGGCATTTTCTATGGGCTCAGGTTA CACCTTCCCAGCTGGTGTTTCTGTCCCAGGAACCTTTCTTCAGCCTACAGCTCACTCTCCAGCAGGAAACCAGGTGCAAGCTGGGAAACAGTCCCACATT CCTTACAGCCAGCAACGGCCCTCTGGACCAGGGCCAATGAACCAGGGACCTCAACAATCACAGCCACCTTCCCAGCAACCCCTTACATCTTTACCAGCTC AGCCAACAGCACAGTCTACAAGCCAGCTGCAGGTTCAAGCTCTAACTCAGCAACAACAATCCCCTACAAAAGCTGTGCCGGCTTTGGGGAAAAGCCCGCC TCACCACTCTGGATTCCAGCAGTATCAACAGGCAGATGCCTCCAAACAGCTGTGGAATCCCCCTCAGGTTCAAGGCCCATTAGGGAAAATTATGCCTGTG AAACAGCCCTACTACCTTCAGACCCAAGACCCCATAAAACTGTTTGAGCCGTCATTGCAACCTCCTGTAATGCAGCAGCAGCCTCTAGAAAAAAAAATGA AGCCTTTTCCCATGGAGCCATATAACCATAATCCCTCAGAAGTCAAGGTCCCAGAATTCTACTGGGATTCTTCCTACAGCATGGCTGATAACAGATCTGT AATGGCACAGCAAGCAAACATAGACCGCAGGGGCAAACGGTCACCAGGAGTCTTCCGTCCAGAGCAGGATCCTGTACCCAGAATGCCGTTTGAGAAATCC TTATTGGAGAAGCCCTCAGAGCTCATGTCACATTCATCCTCTTTCCTGTCCCTCACCGGATTCTCTCTCAATCAGGAAAGATACCCAAATAATAGTATGT TCAATGAGGTATATGGGAAAAACCTGACATCCAGCTCCAAAGCAGAACTCAGTCCCTCAATGGCCCCCCAGGAAACATCTCTGTATTCCCTTTTTGAAGG GACTCCGTGGTCTCCATCACTTCCTGCCAGTTCAGATCATTCAACACCAGCCAGCCAGTCTCCTCATTCCTCTAACCCAAGCAGCCTACCCAGCTCTCCT CCAACACACAACCATAATTCTGTTCCATTCTCCAATTTTGGACCCATTGGGACTCCAGATAACAGGGATAGAAGGACTGCAGATCGGTGGAAAACTGATA AGCCAGCCATGGGTGGGTTTGGCATTGATTATCTCTCAGCAACGTCATCCTCTGAGAGCAGTTGGCATCAGGCCAGCACTCCGAGTGGCACCTGGACAGG CCATGGCCCTTCCATGGAGGATTCCTCTGCTGTCCTCATGGAAAGCCTAAAGTCTATCTGGTCCAGTTCCATGATGCATCCTGGACCTTCTGCTCTGGAG CAGCTGTTAATGCAGCAGAAGCAGAAACAGCAACGGGGACAAGGCACCATGAACCCTCCACACTGAGGCCAAAGTGGCAACCTGGGAATGAAGGCTCCAT AAACCATGGCATGTTGGGTTTGCAGGACTGGCCCACACAGTCCCCTGCAGGTGGCAGCCCTCTTTTCTGTTTCTCGCTGTCAAGAGGGTGTAAGTATTCC ACCAGCCCGCTGAGTGTGCACGAAATGTTCGCAGTGCAACAAAAAGAAAAATCCATCAGGAACTCTCCGTCCCCCCGGGGCCCTCCGGAGGGAGAGAGAG AGGAACTGCTGTTTATCTCACTCAGTTACTTGGTATCACCGCCTCTCACCTTCTCCATCGTGCATGTCCCCAGCCACATGGGAAGTGAAAGCTGAGAAGG GAAGGCAGATGGGAGAAGCCAATGGGAACTTCTCAGTCCTTTTTTCCTCTTTGGGGAATAAAATAGGAATCCATTAATGATTGCTTTGCTGACTGAGAAT GTAGTTGAAATTATTCTTAAACATCTTTTATTATTATTACTCTCAGTAGTAAAATATCACACTGAATTCTTCCATACACAGGTGTGCTTCTAGTCAGTGT GTAGCAAGGAAAGCCCCGTTCACTGCTCCTGTGAGAGGTTGGTGGTGACAGGATGGGGAACCGACCTCTTCAGCCAGTGGAAATGTTCCATAAGGGAGAG TTCAAGGCCTGTCAGAAGGCTCTGGTAGGCCTTCCTCTGGCCAGGAGACTCCAGCAGGGAATGCCCTTCACTCTGTAGGTGCTCGAGCCCCAATCGAGGA TACAGTGTGGGTGGTGGTGCTGGGCTGGACTAGCAGGTAGACTGCTGTAGGATTTCAAATTACGTTTTTGATTCCTGTACATTTTACAGTCGCACAGCAA GCAGTCTCACAGAAGGCAGGCTAGTCCATTCACAGCCTGACACGTTCTAATAGGTAGAAGCTTTCAGTGTGGTTATTTTTTCTTTGGTTGGTTTTTGTGC CCCCATTCTACTTCCCACCCTCCTGCCCCATCTCCATCCCTTCTTTTACCCAATGCTGTATGCTAGTAATTGTTTTTATTCCTAATGTGTGCAACATCAC ATCTCCCCAAGAAGCAACAGCATGGGGTCCAGCAGTTGGGGCCCAAAAGACAGTCTGAAGAGGAAGGAAGCAGCAGTATCTGCGTAGCCCACAGAGGGCC CAGGCCCCTGCCCAGCTGCAGTCTCCCAGCCTCCACTTTCAGAGTGAAATTCAAGGCAGCACGGACATGTGCCCATCAGGCACAGAAGAAAACACGACGT CGTCCATTTTGGAAGAGACGAAAGAAAGGAAAATAAACTCTTTGTATGATATTTATTAGGAGGAAAGAGGACTGAAAATGTTCTTGTGTAGAAACAGAAG GACAGCATTTCTGTTAGTCATTTCCTGGAAAAGTAATATTTTAAGGGGAAATTATGGAAACAATCTAATTGTTCAATTGCTGTGCTAGTGGTAGGGTTTA TTTTCTGGGAGGTCTCTCCTTTGTGTGTCTGTATGTTTGTGTACACACACGTGCCCATCTGCTGTCCCAGAGGGGAGGGGTTGTGTGTGCGAGTGTATGG AGTTAGTGTGGAACTTAAGAGCTGGAAGACAGCTGTAGAGCAAAGCACATCCAGGAGCCCCAGTTGTCACTGCAGTCTGGGCAACCCCAGCAATGAAAAG GGGTGAGATAACGCTCATTGCTCTTCAGAGAGAGTGGTTGGAGCCCCCCCCGCCCCGTATGCTTACATTATTGCTCTTTTAGTTTGACATGGTGTTTGGG TTTTGTTTTTTTGAAAGGTCTGAAAAGGTGAAGCCCCCTACCCAATGGCAATATGAAACCTTTTGTGCTTCTCTTCAGCCCCTTCCCTGTGTCCACCTTT CTCTCCTCTTCCCAAGCCTTTTTCCTACTACCTTTACCCAGTTTGTGTGTTTGAGCTCTGCATTCAGGCAGCTGCAACATTCCAGTGTTTGAACTGTCAC TGATTCTTGCGCCCTAGACAAGCTAACCAGGTTTACCATCTCACTCCCAGTAATACCCAGCTCCTATCTAAAGCCCCATTCTGCATGAGAATTTGGTGTT TGGAATGTTTTCTGACTCTTGGGGCGGGATTCCTCGCCTTATCATCCTCACTGTGGAGTAATGAGGGGGAGGAGAATCTTTATCAGAAACTGGTTTTGTG TAGTAAACTTTCTTTTGTGGTTTTTTGTTTTGTTTTCTGGGTTTTGTTTTTTGTTTTTGTCTGTGCAAGACCTGCAGCTGCTGAAAATCAGCTTTGCCTT TAATTAAACCATGTTCTCTCCAACCA

refseq_SMG7.F3 (forward primer)
refseq_SMG7.R3 (reverse primer)
Single exon skipping

Frame 0

EEPEERKMAAAASTRGAAGPLRGA*ETHGGFAG RRGGGGGG*ACRARSTSDSKLGPAEVWTSRQALQ DLYQKMLVTDLEYALDKKVEQDLWNHAFKNQIT TLQGQAKNRANPNRSEVQANLSLFLEAASGFYT QLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTS AIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQ AESYYRHAAQLVPSNGQPYNQLAILASSKGDHL TTIFYYCRSIAVKFPFPAASTNLQKALSKALESR DEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLS PLREKLEEQFKRLLFQKAFNSQQLVHVTVINLF QLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMS FLGILCKCPLQNESQEESYNAYPLPAVKVSMDW LRLRPRVFQEAVVDERQYIWPWLISLLNSFHPH EEDLSSISATPLPEEFELQGFLALRPSFRNLDFS KGHQGITGDKEGQQRRIRQQRLISIGKWIADNQ PRLIQCENEVGKLLFITEIPELILEDPSEAKEN LILQETSVIESLAADGSPGLKSVLSTSRNLSNNC DTGEKPVVTFKENIKTREVNRDQGRSFPPKEVK SQTELRKTPVSEARKTPVTQTPTQASNSQFIPI HHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGY TFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPA QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPP HHSGFQQYQQADASKQLWNPPQVQGPLGKIMPV KQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKM KPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSV MAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKS LLEKPSELMSHSSSFLSLTGFSLNQERYPNNSM FNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEG TPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTD KPAMGGFGIDYLSATSSSESSWHQASTPSGTWTG HGPSMEDSSAVLMESLKSIWSSSMMHPGPSALE QLLMQQKQKQQRGQGTMNPPH*GQSGNLGMKAP *TMACWVCRTGPHSPLQVAALFSVSRCQEGVSIP PAR*VCTKCSQCNKKKNPSGTLRPPGALRRERE RNCCLSHSVTWYHRLSPSPSCMSPATWEVKAEK GRQMGEANGNFSVLFSSLGNKIGIH**LLC*LRM *LKLFLNIFYYYYSQ**NITLNSSIHRCASSQC VARKAPFTAPVRGWW*QDGEPTSSASGNVP*GR VQGLSEGSGRPSSGQETPAGNALHSVGARAPIED TVWVVVLGWTSR*TAVGFQITFLIPVHFTVAQQ AVSQKAG*SIHSLTRSNR*KLSVWLFFLWLVFV PPFYFPPSCPISIPSFTQCCMLVIVFIPNVCNIT SPQEATAWGPAVGAQKTV*RGRKQQYLRSPQRA QAPAQLQSPSLHFQSEIQGSTDMCPSGTEENTT SSILEETKERKINSLYDIY*EERGLKMFLCRNRR TAFLLVISWKSNILRGNYGNNLIVQLLC*W*GL FSGRSLLCVSVCLCTHTCPSAVPEGRGCVCECM ELVWNLRAGRQL*SKAHPGAPVVTAVWATPAMKR GEITLIALQREWLEPPPPRMLTLLLF*FDMVFG FCFFERSEKVKPPTQWQYETFCASLQPLPCVHL SLLFPSLFPTTFTQFVCLSSAFRQLQHSSV*TVT DSCALDKLTRFTISLPVIPSSYLKPHSA*EFGV WNVF*LLGRDSSPYHPHCGVMRGRRIFIRNWFC VVNFLLWFFVLFSGFCFLFLSVQDLQLLKISFAF N*TMFSPT

Frame 1

RSRRRGRWRRPPAPAVPRGRSEEPERPTEASRE DAAAAAEDEPAERAVPPILSWVQLKSGHPGRLC RTCTRKC*LPIWNTL*TRK*NRISGITPLRIRSQ HCKARQRIEQIRIGVKFRQTFLCS*RQLVASIL SYYKNCVQYLM*IYHAV*SLPNWELSAINRRIP AP**SHSLAPVPISASTASSTLETLLDTETRPAR QSPTIGMQLSLSPPMVSLIISWLS*LLPKETI* PQFSTTAEALL*SSLSQLPPLICKKHFLKHWKA EMR*KPSGVFLTSSRPLLNSTVMCT*VRAWKS*A LFERNWKNSLRGCYSKKLSTLSS*FMSLSLTCF NFITFVTLAMKPSSTLIAKMSSYVGHSCWPSLC LFLASCASVLYRMSLRRSPTMPILFQQSRSPWTG *DSDPGSFRRQWWMKDSTFGPG*FLF*IVSIPM KRTSQVLVRHHFQRSLNYKDFWH*DLLSGTWIF PKVTRVLQGTKKASNDEYDSNA*SL*ANGLLIIS QG*FSVKMR*GNCCLSQKSQN*YWKTPVKPKRT SFCKKHL**SRWLQMGAQG*NQCYLQAEI*ATT VTQERSQWLPSKKTLRHEK*TETKEEVFLPKR*N PRQN*ERLQCLKPEKHL*LKPQLKQVTPSSSPF ITLEPSLLFPAGQGFRPQHMLSPRLWHFLWAQV TPSQLVFLSQEPFFSLQLTLQQETRCKLGNSPTF LTASNGPLDQGQ*TRDLNNHSHLPSNPLHLYQL SQQHSLQASCRFKL*LSNNNPLQKLCRLWGKAR LTTLDSSSINRQMPPNSCGIPLRFKAH*GKLCL* NSPTTFRPKTP*NCLSRHCNLL*CSSSL*KKK* SLFPWSHITIIPQKSRSQNSTGILPTAWLITDL *WHSKQT*TAGANGHQESSVQSRILYPECRLRNP YWRSPQSSCHIHPLSCPSPDSLSIRKDTQIIVC SMRYMGKT*HPAPKQNSVPQWPPRKHLCIPFLK GLRGLHHFLPVQIIQHQPASLLIPLTQAAYPALL QHTTIILFHSPILDPLGLQITGIEGLQIGGKLI SQPWVGLALIISQQRHPLRAVGIRPALRVAPGQ AMALPWRIPLLSSWKA*SLSGPVP*CILDLLLWS SC*CSRSRNSNGDKAP*TLHTEAKVATWE*RLH KPWHVGFAGLAHTVPCRWQPSFLFLAVKRV*VF HQPAECARNVRSATKRKIHQELSVPPGPSGGRER GTAVYLTQLLGITASHLLHRACPQPHGK*KLRR EGRWEKPMGTSQSFFPLWGIK*ESINDCFAD*E CS*NYS*TSFIIITLSSKISH*ILPYTGVLLVSV *QGKPRSLLL*EVGGDRMGNRPLQPVEMFHKGE FKACQKALVGLPLARRLQQGMPFTL*VLEPQSR IQCGWWCWAGLAGRLL*DFKLRF*FLYILQSHSK QSHRRQASPFTA*HVLIGRSFQCGYFFFGWFLC PHSTSHPPAPSPSLLLPNAVC**LFLFLMCATS HLPKKQQHGVQQLGPKRQSEEEGSSSICVAHRGP RPLPSCSLPASTFRVKFKAARTCAHQAQKKTRR RPFWKRRKKGK*TLCMIFIRRKED*KCSCVETE GQHFC*SFPGKVIF*GEIMETI*LFNCCASGRVY FLGGLSFVCLYVCVHTRAHLLSQRGGVVCASVW S*CGT*ELEDSCRAKHIQEPQLSLQSGQPQQ*K GVR*RSLLFRESGWSPPRPVCLHYCSFSLTWCLG FVFLKGLKR*SPLPNGNMKPFVLLFSPFPVSTF LSSSQAFFLLPLPSLCV*ALHSGSCNIPVFELS LILAP*TS*PGLPSHSQ*YPAPI*SPILHENLVF GMFSDSWGGIPRLIILTVE**GGGESLSETGFV **TFFCGFLFCFLGFVFCFCLCKTCSC*KSALP LIKPCSLQP

Frame 2

GAGGEEDGGGRQHPRCRGAAPRSLRDPRRLRGK TRRRRRRMSLQSAQYLRF*AGSS*SLDIQAGSA GPVPENASYRFGIRFRQESRTGSLESRL*ESDH NTARPGKESSKSESE*SSGKPFSVPRGS*WLLYS VITRTVYSI*CRFTMPCEVFPIGNYQQ*TDAYQ RHSEATV*LLFLYLPALPRPPWRHCSIQKPDQP GRVLL*ACSSACPLQWSAL*SVGYLSFFQRRPSD HNFLLLQKHCCEVPFPSCLH*SAKSTF*STGKP R*GENQVGCF*LHQGLY*IPRSCVPE*ELGKVE PSSREIGRTV*EAAIPKSFQLSAVSSCHCH*PVS TSSPS*L*Q*NRAAHL*PR*AAMLDTVAGPLYV FSWHPVQVSSTE*VSGGVLQCLSSSSSQGLHGL AKTQTQGLSGGSGG*KTVHLALVDFSSE*FPSP* RGPLKY*CDTTSRGV*ITRIFGIETFFQELGFF QRSPGYYRGQRRPATTNTTATLDLYRQMDC**S AKADSV*K*GREIVVYHRNPRINTGRPQ*SQREP HSARNICDRVAGCRWEPRAKISAIYKPKFKQQL *HRREASGYLQRKH*DTRSEQRPRKKFSSQRGK IPDRTKKDSSV*SQKNTCNSNPNSSK*LPVHPHS SPWSLPSSSQQARVSAPNICYPPACGIFYGLRL HLPSWCFCPRNLSSAYSSLSSRKPGASWETVPH SLQPATALWTRANEPGTSTITATFPATPYIFTSS ANSTVYKPAAGSSSNSATTIPYKSCAGFGEKPA SPLWIPAVSTGRCLQTAVESPSGSRPIRENYAC ETALLPSDPRPHKTV*AVIATSCNAAAASRKKNE AFSHGAI*P*SLRSQGPRILLGFFLQHG**QIC NGTASKHRPQGQTVTRSLPSRAGSCTQNAV*EI LIGEALRAHVTFILFPVPHRILSQSGKIPK**YV Q*GIWEKPDIQLQSRTQSLNGPPGNISVFPF*R DSVVSITSCQFRSFNTSQPVSSFL*PKQPTQLS SNTQP*FCSILQFWTHWDSR*QG*KDCRSVEN** ASHGWVWH*LSLSNVIL*EQLASGQHSEWHLDR PWPFHGGFLCCPHGKPKVYLVQFHDASWTFCSG AAVNAAEAETATGTRHHEPSTLRPKWQPGNEGSI NHGMLGLQDWPTQSPAGGSPLFCFSLSRGCKYS TSPLSVHEMFAVQQKEKSIRNSPSPRGPPEGER EELLFISLSYLVSPPLTFSIVHVPSHMGSES*EG KADGRSQWELLSPFFLFGE*NRNPLMIALLTEN VVEIILKHLLLLLLSVVKYHTEFFHTQVCF*SV CSKESPVHCSCERLVVTGWGTDLFSQWKCSIRES SRPVRRLW*AFLWPGDSSRECPSLCRCSSPNRG YSVGGGAGLD*QVDCCRISNYVFDSCTFYSRTA SSLTEGRLVHSQPDTF**VEAFSVVIFSLVGFCA PILLPTLLPHLHPFFYPMLYASNCFYS*CVQHH ISPRSNSMGSSSWGPKDSLKRKEAAVSA*PTEG PGPCPAAVSQPPLSE*NSRQHGHVPIRHRRKHDV VHFGRDERKENKLFV*YLLGGKRTENVLV*KQK DSISVSHFLEK*YFKGKLWKQSNCSIAVLVVGF IFWEVSPLCVCMFVYTHVPICCPRGEGLCVRVYG VSVELKSWKTAVEQSTSRSPSCHCSLGNPSNEK G*DNAHCSSERVVGAPPAPYAYIIALLV*HGVW VLFF*KV*KGEAPYPMAI*NLLCFSSAPSLCPPF SPLPKPFSYYLYPVCVFELCIQAAATFQCLNCH *FLRPRQANQVYHLTPSNTQLLSKAPFCMRIWC LECFLTLGAGFLALSSSLWSNEGEENLYQKLVLC SKLSFVVFCFVFWVLFFVFVCARPAAAENQLCL *LNHVLSN

Sequence NM_201568

GAGGAGCCGGAGGAGAGGAAGATGGCGGCGGCCGCCAGCACCCGCGGTGCCGCGGGGCCGCTCCGAGGAGCCTGAGAGACCCACGGAGGCTTCGCGGGAA GACGCGGCGGCGGCGGCGGAGGATGAGCCTGCAGAGCGCGCAGTACCTCCGGCAGGCAGAAGTCCTGAAGGCTGACATGACAGATTCTAAGCTGGGTCCA GCTGAAGTCTGGACATCCAGGCAGGCTCTGCAGGACCTGTACCAGAAAATGCTAGTTACCGATTTGGAATACGCTTTAGACAAGAAAGTAGAACAGGATC TCTGGAATCACGCCTTTAAGAATCAGATCACAACACTGCAAGGCCAGGCAAAGAATCGAGCAAATCCGAATCGGAGTGAAGTTCAGGCAAACCTTTCTCT GTTCCTAGAGGCAGCTAGTGGCTTCTATACTCAGTTATTACAAGAACTGTGTACAGTATTTAATGTAGATTTACCATGCCGTGTGAAGTCTTCCCAATTG GGAATTATCAGCAATAAACAGACGCATACCAGCGCCATAGTGAAGCCACAGTCTAGCTCCTGTTCCTATATCTGCCAGCACTGCCTCGTCCACCTTGGAG ACATTGCTCGATACAGAAACCAGACCAGCCAGGCAGAGTCCTACTATAGGCATGCAGCTCAGCTTGTCCCCTCCAATGGTCAGCCTTATAATCAGTTGGC TATCTTAGCTTCTTCCAAAGGAGACCATCTGACCACAATTTTCTACTACTGCAGAAGCATTGCTGTGAAGTTCCCTTTCCCAGCTGCCTCCACTAATCTG CAAAAAGCACTTTCTAAAGCACTGGAAAGCCGAGATGAGGTGAAAACCAAGTGGGGTGTTTCTGACTTCATCAAGGCCTTTATTAAATTCCACGGTCATG TGTACCTGAGTAAGAGCTTGGAAAAGTTGAGCCCTCTTCGAGAGAAATTGGAAGAACAGTTTAAGAGGCTGCTATTCCAAAAAGCTTTCAACTCTCAGCA GTTAGTTCATGTCACTGTCATTAACCTGTTTCAACTTCATCACCTTCGTGACTTTAGCAATGAAACCGAGCAGCACACTTATAGCCAAGATGAGCAGCTA TGTTGGACACAGTTGCTGGCCCTCTTTATGTCTTTTCTTGGCATCCTGTGCAAGTGTCCTCTACAGAATGAGTCTCAGGAGGAGTCCTACAATGCCTATC CTCTTCCAGCAGTCAAGGTCTCCATGGACTGGCTAAGACTCAGACCCAGGGTCTTTCAGGAGGCAGTGGTGGATGAAAGACAGTACATTTGGCCCTGGTT GATTTCTCTTCTGAATAGTTTCCATCCCCATGAAGAGGACCTCTCAAGTATTAGTGCGACACCACTTCCAGAGGAGTTTGAATTACAAGGATTTTTGGCA TTGAGACCTTCTTTCAGGAACTTGGATTTTTCCAAAGGTCACCAGGGTATTACAGGGGACAAAGAAGGCCAGCAACGACGAATACGACAGCAACGCTTGA TCTCTATAGGCAAATGGATTGCTGATAATCAGCCAAGGCTGATTCAGTGTGAAAATGAGGTAGGGAAATTGTTGTTTATCACAGAAATCCCAGAATTAAT ACTGGAAGACCCCAGTGAAGCCAAAGAGAACCTCATTCTGCAAGAAACATCTGTGATAGAGTCGCTGGCTGCAGATGGGAGCCCAGGGCTAAAATCAGTG CTATCTACAAGCCGAAATTTAAGCAACAACTGTGACACAGGAGAGAAGCCAGTGGTTACCTTCAAAGAAAACATTAAGACACGAGAAGTGAACAGAGACC AAGGAAGAAGTTTTCCTCCCAAAGAGGTAAAATCCCAGACAGAACTAAGAAAGACTCCAGTGTCTGAAGCCAGAAAAACACCTGTAACTCAAACCCCAAC TCAAGCAAGTAACTCCCAGTTCATCCCCATTCATCACCCTGGAGCCTTCCCTCCTCTTCCCAGCAGGCCAGGGTTTCCGCCCCCAACATATGTTATCCCC CCGCCTGTGGCATTTTCTATGGGCTCAGGTTACACCTTCCCAGCTGGTGTTTCTGTCCCAGGAACCTTTCTTCAGCCTACAGCTCACTCTCCAGCAGGAA ACCAGGTGCAAGCTGGGAAACAGTCCCACATTCCTTACAGCCAGCAACGGCCCTCTGGACCAGGGCCAATGAACCAGGGACCTCAACAATCACAGCCACC TTCCCAGCAACCCCTTACATCTTTACCAGCTCAGCCAACAGCACAGTCTACAAGCCAGCTGCAGGTTCAAGCTCTAACTCAGCAACAACAATCCCCTACA AAAGCTGTGCCGGCTTTGGGGAAAAGCCCGCCTCACCACTCTGGATTCCAGCAGTATCAACAGGCAGATGCCTCCAAACAGCTGTGGAATCCCCCTCAGG TTCAAGGCCCATTAGGGAAAATTATGCCTGTGAAACAGCCCTACTACCTTCAGACCCAAGACCCCATAAAACTGTTTGAGCCGTCATTGCAACCTCCTGT AATGCAGCAGCAGCCTCTAGAAAAAAAAATGAAGCCTTTTCCCATGGAGCCATATAACCATAATCCCTCAGAAGTCAAGGTCCCAGAATTCTACTGGGAT TCTTCCTACAGCATGGCTGATAACAGATCTGTAATGGCACAGCAAGCAAACATAGACCGCAGGGGCAAACGGTCACCAGGAGTCTTCCGTCCAGAGCAGG ATCCTGTACCCAGAATGCCGTTTGAGAAATCCTTATTGGAGAAGCCCTCAGAGCTCATGTCACATTCATCCTCTTTCCTGTCCCTCACCGGATTCTCTCT CAATCAGGAAAGATACCCAAATAATAGTATGTTCAATGAGGTATATGGGAAAAACCTGACATCCAGCTCCAAAGCAGAACTCAGTCCCTCAATGGCCCCC CAGGAAACATCTCTGTATTCCCTTTTTGAAGGGACTCCGTGGTCTCCATCACTTCCTGCCAGTTCAGATCATTCAACACCAGCCAGCCAGTCTCCTCATT CCTCTAACCCAAGCAGCCTACCCAGCTCTCCTCCAACACACAACCATAATTCTGTTCCATTCTCCAATTTTGGACCCATTGGGACTCCAGATAACAGGGA TAGAAGGACTGCAGATCGGTGGAAAACTGATAAGCCAGCCATGGGTGGGTTTGGCATTGATTATCTCTCAGCAACGTCATCCTCTGAGAGCAGTTGGCAT CAGGCCAGCACTCCGAGTGGCACCTGGACAGGCCATGGCCCTTCCATGGAGGATTCCTCTGCTGTCCTCATGGAAAGCCTAAAGTCTATCTGGTCCAGTT CCATGATGCATCCTGGACCTTCTGCTCTGGAGCAGCTGTTAATGCAGCAGAAGCAGAAACAGCAACGGGGACAAGGCACCATGAACCCTCCACACTGAGG CCAAAGTGGCAACCTGGGAATGAAGGCTCCATAAACCATGGCATGTTGGGTTTGCAGGACTGGCCCACACAGTCCCCTGCAGGTGGCAGCCCTCTTTTCT GTTTCTCGCTGTCAAGAGGGTGTAAGTATTCCACCAGCCCGCTGAGTGTGCACGAAATGTTCGCAGTGCAACAAAAAGAAAAATCCATCAGGAACTCTCC GTCCCCCCGGGGCCCTCCGGAGGGAGAGAGAGAGGAACTGCTGTTTATCTCACTCAGTTACTTGGTATCACCGCCTCTCACCTTCTCCATCGTGCATGTC CCCAGCCACATGGGAAGTGAAAGCTGAGAAGGGAAGGCAGATGGGAGAAGCCAATGGGAACTTCTCAGTCCTTTTTTCCTCTTTGGGGAATAAAATAGGA ATCCATTAATGATTGCTTTGCTGACTGAGAATGTAGTTGAAATTATTCTTAAACATCTTTTATTATTATTACTCTCAGTAGTAAAATATCACACTGAATT CTTCCATACACAGGTGTGCTTCTAGTCAGTGTGTAGCAAGGAAAGCCCCGTTCACTGCTCCTGTGAGAGGTTGGTGGTGACAGGATGGGGAACCGACCTC TTCAGCCAGTGGAAATGTTCCATAAGGGAGAGTTCAAGGCCTGTCAGAAGGCTCTGGTAGGCCTTCCTCTGGCCAGGAGACTCCAGCAGGGAATGCCCTT CACTCTGTAGGTGCTCGAGCCCCAATCGAGGATACAGTGTGGGTGGTGGTGCTGGGCTGGACTAGCAGGTAGACTGCTGTAGGATTTCAAATTACGTTTT TGATTCCTGTACATTTTACAGTCGCACAGCAAGCAGTCTCACAGAAGGCAGGCTAGTCCATTCACAGCCTGACACGTTCTAATAGGTAGAAGCTTTCAGT GTGGTTATTTTTTCTTTGGTTGGTTTTTGTGCCCCCATTCTACTTCCCACCCTCCTGCCCCATCTCCATCCCTTCTTTTACCCAATGCTGTATGCTAGTA ATTGTTTTTATTCCTAATGTGTGCAACATCACATCTCCCCAAGAAGCAACAGCATGGGGTCCAGCAGTTGGGGCCCAAAAGACAGTCTGAAGAGGAAGGA AGCAGCAGTATCTGCGTAGCCCACAGAGGGCCCAGGCCCCTGCCCAGCTGCAGTCTCCCAGCCTCCACTTTCAGAGTGAAATTCAAGGCAGCACGGACAT GTGCCCATCAGGCACAGAAGAAAACACGACGTCGTCCATTTTGGAAGAGACGAAAGAAAGGAAAATAAACTCTTTGTATGATATTTATTAGGAGGAAAGA GGACTGAAAATGTTCTTGTGTAGAAACAGAAGGACAGCATTTCTGTTAGTCATTTCCTGGAAAAGTAATATTTTAAGGGGAAATTATGGAAACAATCTAA TTGTTCAATTGCTGTGCTAGTGGTAGGGTTTATTTTCTGGGAGGTCTCTCCTTTGTGTGTCTGTATGTTTGTGTACACACACGTGCCCATCTGCTGTCCC AGAGGGGAGGGGTTGTGTGTGCGAGTGTATGGAGTTAGTGTGGAACTTAAGAGCTGGAAGACAGCTGTAGAGCAAAGCACATCCAGGAGCCCCAGTTGTC ACTGCAGTCTGGGCAACCCCAGCAATGAAAAGGGGTGAGATAACGCTCATTGCTCTTCAGAGAGAGTGGTTGGAGCCCCCCCCGCCCCGTATGCTTACAT TATTGCTCTTTTAGTTTGACATGGTGTTTGGGTTTTGTTTTTTTGAAAGGTCTGAAAAGGTGAAGCCCCCTACCCAATGGCAATATGAAACCTTTTGTGC TTCTCTTCAGCCCCTTCCCTGTGTCCACCTTTCTCTCCTCTTCCCAAGCCTTTTTCCTACTACCTTTACCCAGTTTGTGTGTTTGAGCTCTGCATTCAGG CAGCTGCAACATTCCAGTGTTTGAACTGTCACTGATTCTTGCGCCCTAGACAAGCTAACCAGGTTTACCATCTCACTCCCAGTAATACCCAGCTCCTATC TAAAGCCCCATTCTGCATGAGAATTTGGTGTTTGGAATGTTTTCTGACTCTTGGGGCGGGATTCCTCGCCTTATCATCCTCACTGTGGAGTAATGAGGGG GAGGAGAATCTTTATCAGAAACTGGTTTTGTGTAGTAAACTTTCTTTTGTGGTTTTTTGTTTTGTTTTCTGGGTTTTGTTTTTTGTTTTTGTCTGTGCAA GACCTGCAGCTGCTGAAAATCAGCTTTGCCTTTAATTAAACCATGTTCTCTCCAACCA

refseq_SMG7.F3 (forward primer)
refseq_SMG7.R3 (reverse primer)
Single exon skipping

Frame 0

EEPEERKMAAAASTRGAAGPLRGA*ETHGGFAG RRGGGGGG*ACRARSTSGRQKS*RLT*QILSWVQ LKSGHPGRLCRTCTRKC*LPIWNTL*TRK*NRI SGITPLRIRSQHCKARQRIEQIRIGVKFRQTFL CS*RQLVASILSYYKNCVQYLM*IYHAV*SLPNW ELSAINRRIPAP**SHSLAPVPISASTASSTLE TLLDTETRPARQSPTIGMQLSLSPPMVSLIISW LS*LLPKETI*PQFSTTAEALL*SSLSQLPPLIC KKHFLKHWKAEMR*KPSGVFLTSSRPLLNSTVM CT*VRAWKS*ALFERNWKNSLRGCYSKKLSTLS S*FMSLSLTCFNFITFVTLAMKPSSTLIAKMSSY VGHSCWPSLCLFLASCASVLYRMSLRRSPTMPI LFQQSRSPWTG*DSDPGSFRRQWWMKDSTFGPG *FLF*IVSIPMKRTSQVLVRHHFQRSLNYKDFWH *DLLSGTWIFPKVTRVLQGTKKASNDEYDSNA* SL*ANGLLIISQG*FSVKMR*GNCCLSQKSQN* YWKTPVKPKRTSFCKKHL**SRWLQMGAQG*NQC YLQAEI*ATTVTQERSQWLPSKKTLRHEK*TET KEEVFLPKR*NPRQN*ERLQCLKPEKHL*LKPQ LKQVTPSSSPFITLEPSLLFPAGQGFRPQHMLSP RLWHFLWAQVTPSQLVFLSQEPFFSLQLTLQQE TRCKLGNSPTFLTASNGPLDQGQ*TRDLNNHSH LPSNPLHLYQLSQQHSLQASCRFKL*LSNNNPLQ KLCRLWGKARLTTLDSSSINRQMPPNSCGIPLR FKAH*GKLCL*NSPTTFRPKTP*NCLSRHCNLL *CSSSL*KKK*SLFPWSHITIIPQKSRSQNSTGI LPTAWLITDL*WHSKQT*TAGANGHQESSVQSR ILYPECRLRNPYWRSPQSSCHIHPLSCPSPDSL SIRKDTQIIVCSMRYMGKT*HPAPKQNSVPQWPP RKHLCIPFLKGLRGLHHFLPVQIIQHQPASLLI PLTQAAYPALLQHTTIILFHSPILDPLGLQITG IEGLQIGGKLISQPWVGLALIISQQRHPLRAVGI RPALRVAPGQAMALPWRIPLLSSWKA*SLSGPV P*CILDLLLWSSC*CSRSRNSNGDKAP*TLHTE AKVATWE*RLHKPWHVGFAGLAHTVPCRWQPSFL FLAVKRV*VFHQPAECARNVRSATKRKIHQELS VPPGPSGGRERGTAVYLTQLLGITASHLLHRAC PQPHGK*KLRREGRWEKPMGTSQSFFPLWGIK*E SINDCFAD*ECS*NYS*TSFIIITLSSKISH*I LPYTGVLLVSV*QGKPRSLLL*EVGGDRMGNRP LQPVEMFHKGEFKACQKALVGLPLARRLQQGMPF TL*VLEPQSRIQCGWWCWAGLAGRLL*DFKLRF *FLYILQSHSKQSHRRQASPFTA*HVLIGRSFQ CGYFFFGWFLCPHSTSHPPAPSPSLLLPNAVC** LFLFLMCATSHLPKKQQHGVQQLGPKRQSEEEG SSSICVAHRGPRPLPSCSLPASTFRVKFKAART CAHQAQKKTRRRPFWKRRKKGK*TLCMIFIRRKE D*KCSCVETEGQHFC*SFPGKVIF*GEIMETI* LFNCCASGRVYFLGGLSFVCLYVCVHTRAHLLS QRGGVVCASVWS*CGT*ELEDSCRAKHIQEPQLS LQSGQPQQ*KGVR*RSLLFRESGWSPPRPVCLH YCSFSLTWCLGFVFLKGLKR*SPLPNGNMKPFV LLFSPFPVSTFLSSSQAFFLLPLPSLCV*ALHSG SCNIPVFELSLILAP*TS*PGLPSHSQ*YPAPI *SPILHENLVFGMFSDSWGGIPRLIILTVE**G GGESLSETGFV**TFFCGFLFCFLGFVFCFCLCK TCSC*KSALPLIKPCSLQP

Frame 1

RSRRRGRWRRPPAPAVPRGRSEEPERPTEASRE DAAAAAEDEPAERAVPPAGRSPEG*HDRF*AGS S*SLDIQAGSAGPVPENASYRFGIRFRQESRTGS LESRL*ESDHNTARPGKESSKSESE*SSGKPFS VPRGS*WLLYSVITRTVYSI*CRFTMPCEVFPI GNYQQ*TDAYQRHSEATV*LLFLYLPALPRPPWR HCSIQKPDQPGRVLL*ACSSACPLQWSAL*SVG YLSFFQRRPSDHNFLLLQKHCCEVPFPSCLH*S AKSTF*STGKPR*GENQVGCF*LHQGLY*IPRSC VPE*ELGKVEPSSREIGRTV*EAAIPKSFQLSA VSSCHCH*PVSTSSPS*L*Q*NRAAHL*PR*AA MLDTVAGPLYVFSWHPVQVSSTE*VSGGVLQCLS SSSSQGLHGLAKTQTQGLSGGSGG*KTVHLALV DFSSE*FPSP*RGPLKY*CDTTSRGV*ITRIFG IETFFQELGFFQRSPGYYRGQRRPATTNTTATLD LYRQMDC**SAKADSV*K*GREIVVYHRNPRIN TGRPQ*SQREPHSARNICDRVAGCRWEPRAKIS AIYKPKFKQQL*HRREASGYLQRKH*DTRSEQRP RKKFSSQRGKIPDRTKKDSSV*SQKNTCNSNPN SSK*LPVHPHSSPWSLPSSSQQARVSAPNICYP PACGIFYGLRLHLPSWCFCPRNLSSAYSSLSSRK PGASWETVPHSLQPATALWTRANEPGTSTITAT FPATPYIFTSSANSTVYKPAAGSSSNSATTIPY KSCAGFGEKPASPLWIPAVSTGRCLQTAVESPSG SRPIRENYACETALLPSDPRPHKTV*AVIATSC NAAAASRKKNEAFSHGAI*P*SLRSQGPRILLG FFLQHG**QICNGTASKHRPQGQTVTRSLPSRAG SCTQNAV*EILIGEALRAHVTFILFPVPHRILS QSGKIPK**YVQ*GIWEKPDIQLQSRTQSLNGP PGNISVFPF*RDSVVSITSCQFRSFNTSQPVSSF L*PKQPTQLSSNTQP*FCSILQFWTHWDSR*QG *KDCRSVEN**ASHGWVWH*LSLSNVIL*EQLA SGQHSEWHLDRPWPFHGGFLCCPHGKPKVYLVQF HDASWTFCSGAAVNAAEAETATGTRHHEPSTLR PKWQPGNEGSINHGMLGLQDWPTQSPAGGSPLF CFSLSRGCKYSTSPLSVHEMFAVQQKEKSIRNSP SPRGPPEGEREELLFISLSYLVSPPLTFSIVHV PSHMGSES*EGKADGRSQWELLSPFFLFGE*NR NPLMIALLTENVVEIILKHLLLLLLSVVKYHTEF FHTQVCF*SVCSKESPVHCSCERLVVTGWGTDL FSQWKCSIRESSRPVRRLW*AFLWPGDSSRECP SLCRCSSPNRGYSVGGGAGLD*QVDCCRISNYVF DSCTFYSRTASSLTEGRLVHSQPDTF**VEAFS VVIFSLVGFCAPILLPTLLPHLHPFFYPMLYAS NCFYS*CVQHHISPRSNSMGSSSWGPKDSLKRKE AAVSA*PTEGPGPCPAAVSQPPLSE*NSRQHGH VPIRHRRKHDVVHFGRDERKENKLFV*YLLGGK RTENVLV*KQKDSISVSHFLEK*YFKGKLWKQSN CSIAVLVVGFIFWEVSPLCVCMFVYTHVPICCP RGEGLCVRVYGVSVELKSWKTAVEQSTSRSPSC HCSLGNPSNEKG*DNAHCSSERVVGAPPAPYAYI IALLV*HGVWVLFF*KV*KGEAPYPMAI*NLLC FSSAPSLCPPFSPLPKPFSYYLYPVCVFELCIQ AAATFQCLNCH*FLRPRQANQVYHLTPSNTQLLS KAPFCMRIWCLECFLTLGAGFLALSSSLWSNEG EENLYQKLVLCSKLSFVVFCFVFWVLFFVFVCA RPAAAENQLCL*LNHVLSN

Frame 2

GAGGEEDGGGRQHPRCRGAAPRSLRDPRRLRGK TRRRRRRMSLQSAQYLRQAEVLKADMTDSKLGP AEVWTSRQALQDLYQKMLVTDLEYALDKKVEQD LWNHAFKNQITTLQGQAKNRANPNRSEVQANLSL FLEAASGFYTQLLQELCTVFNVDLPCRVKSSQL GIISNKQTHTSAIVKPQSSSCSYICQHCLVHLG DIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLA ILASSKGDHLTTIFYYCRSIAVKFPFPAASTNL QKALSKALESRDEVKTKWGVSDFIKAFIKFHGH VYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQ LVHVTVINLFQLHHLRDFSNETEQHTYSQDEQL CWTQLLALFMSFLGILCKCPLQNESQEESYNAY PLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWL ISLLNSFHPHEEDLSSISATPLPEEFELQGFLA LRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRL ISIGKWIADNQPRLIQCENEVGKLLFITEIPELI LEDPSEAKENLILQETSVIESLAADGSPGLKSV LSTSRNLSNNCDTGEKPVVTFKENIKTREVNRD QGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPT QASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIP PPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAG NQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPP SQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPT KAVPALGKSPPHHSGFQQYQQADASKQLWNPPQ VQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPV MQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWD SSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQ DPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSL NQERYPNNSMFNEVYGKNLTSSSKAELSPSMAP QETSLYSLFEGTPWSPSLPASSDHSTPASQSPH SSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRD RRTADRWKTDKPAMGGFGIDYLSATSSSESSWH QASTPSGTWTGHGPSMEDSSAVLMESLKSIWSS SMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH*G QSGNLGMKAP*TMACWVCRTGPHSPLQVAALFS VSRCQEGVSIPPAR*VCTKCSQCNKKKNPSGTL RPPGALRRERERNCCLSHSVTWYHRLSPSPSCMS PATWEVKAEKGRQMGEANGNFSVLFSSLGNKIG IH**LLC*LRM*LKLFLNIFYYYYSQ**NITLN SSIHRCASSQCVARKAPFTAPVRGWW*QDGEPTS SASGNVP*GRVQGLSEGSGRPSSGQETPAGNAL HSVGARAPIEDTVWVVVLGWTSR*TAVGFQITF LIPVHFTVAQQAVSQKAG*SIHSLTRSNR*KLSV WLFFLWLVFVPPFYFPPSCPISIPSFTQCCMLV IVFIPNVCNITSPQEATAWGPAVGAQKTV*RGR KQQYLRSPQRAQAPAQLQSPSLHFQSEIQGSTDM CPSGTEENTTSSILEETKERKINSLYDIY*EER GLKMFLCRNRRTAFLLVISWKSNILRGNYGNNL IVQLLC*W*GLFSGRSLLCVSVCLCTHTCPSAVP EGRGCVCECMELVWNLRAGRQL*SKAHPGAPVV TAVWATPAMKRGEITLIALQREWLEPPPPRMLT LLLF*FDMVFGFCFFERSEKVKPPTQWQYETFCA SLQPLPCVHLSLLFPSLFPTTFTQFVCLSSAFR QLQHSSV*TVTDSCALDKLTRFTISLPVIPSSY LKPHSA*EFGVWNVF*LLGRDSSPYHPHCGVMRG RRIFIRNWFCVVNFLLWFFVLFSGFCFLFLSVQ DLQLLKISFAFN*TMFSPT

Sequence NM_173156

GAGGAGCCGGAGGAGAGGAAGATGGCGGCGGCCGCCAGCACCCGCGGTGCCGCGGGGCCGCTCCGAGGAGCCTGAGAGACCCACGGAGGCTTCGCGGGAA GACGCGGCGGCGGCGGCGGAGGATGAGCCTGCAGAGCGCGCAGTACCTCCGGCAGGCAGAAGTCCTGAAGGCTGACATGACAGATTCTAAGCTGGGTCCA GCTGAAGTCTGGACATCCAGGCAGGCTCTGCAGGACCTGTACCAGAAAATGCTAGTTACCGATTTGGAATACGCTTTAGACAAGAAAGTAGAACAGGATC TCTGGAATCACGCCTTTAAGAATCAGATCACAACACTGCAAGGCCAGGCAAAGAATCGAGCAAATCCGAATCGGAGTGAAGTTCAGGCAAACCTTTCTCT GTTCCTAGAGGCAGCTAGTGGCTTCTATACTCAGTTATTACAAGAACTGTGTACAGTATTTAATGTAGATTTACCATGCCGTGTGAAGTCTTCCCAATTG GGAATTATCAGCAATAAACAGACGCATACCAGCGCCATAGTGAAGCCACAGTCTAGCTCCTGTTCCTATATCTGCCAGCACTGCCTCGTCCACCTTGGAG ACATTGCTCGATACAGAAACCAGACCAGCCAGGCAGAGTCCTACTATAGGCATGCAGCTCAGCTTGTCCCCTCCAATGGTCAGCCTTATAATCAGTTGGC TATCTTAGCTTCTTCCAAAGGAGACCATCTGACCACAATTTTCTACTACTGCAGAAGCATTGCTGTGAAGTTCCCTTTCCCAGCTGCCTCCACTAATCTG CAAAAAGCACTTTCTAAAGCACTGGAAAGCCGAGATGAGGTGAAAACCAAGTGGGGTGTTTCTGACTTCATCAAGGCCTTTATTAAATTCCACGGTCATG TGTACCTGAGTAAGAGCTTGGAAAAGTTGAGCCCTCTTCGAGAGAAATTGGAAGAACAGTTTAAGAGGCTGCTATTCCAAAAAGCTTTCAACTCTCAGCA GTTAGTTCATGTCACTGTCATTAACCTGTTTCAACTTCATCACCTTCGTGACTTTAGCAATGAAACCGAGCAGCACACTTATAGCCAAGATGAGCAGCTA TGTTGGACACAGTTGCTGGCCCTCTTTATGTCTTTTCTTGGCATCCTGTGCAAGTGTCCTCTACAGAATGAGTCTCAGGAGGAGTCCTACAATGCCTATC CTCTTCCAGCAGTCAAGGTCTCCATGGACTGGCTAAGACTCAGACCCAGGGTCTTTCAGGAGGCAGTGGTGGATGAAAGACAGTACATTTGGCCCTGGTT GATTTCTCTTCTGAATAGTTTCCATCCCCATGAAGAGGACCTCTCAAGTATTAGTGCGACACCACTTCCAGAGGAGTTTGAATTACAAGGATTTTTGGCA TTGAGACCTTCTTTCAGGAACTTGGATTTTTCCAAAGGTCACCAGGGTATTACAGGGGACAAAGAAGGCCAGCAACGACGAATACGACAGCAACGCTTGA TCTCTATAGGCAAATGGATTGCTGATAATCAGCCAAGGCTGATTCAGTGTGAAAATGAGGTAGGGAAATTGTTGTTTATCACAGAAATCCCAGAATTAAT ACTGGAAGACCCCAGTGAAGCCAAAGAGAACCTCATTCTGCAAGAAACATCTGTGATAGAGTCGCTGGCTGCAGATGGGAGCCCAGGGCTAAAATCAGTG CTATCTACAAGCCGAAATTTAAGCAACAACTGTGACACAGGAGAGAAGCCAGTGGTTACCTTCAAAGAAAACATTAAGACACGAGAAGTGAACAGAGACC AAGGAAGAAGTTTTCCTCCCAAAGAGGTGAGAAGGGACTATAGCAAAGGAATAACTGTAACTAAGAATGATGGAAAGAAGGACAACAACAAGAGGAAAAC TGAAACCAAGAAATGCACCTTAGAAAAGTTACAGGAAACAGGAAAGCAGAATGTGGCAGTGCAGGTAAAATCCCAGACAGAACTAAGAAAGACTCCAGTG TCTGAAGCCAGAAAAACACCTGTAACTCAAACCCCAACTCAAGCAAGTAACTCCCAGTTCATCCCCATTCATCACCCTGGAGCCTTCCCTCCTCTTCCCA GCAGGCCAGGGTTTCCGCCCCCAACATATGTTATCCCCCCGCCTGTGGCATTTTCTATGGGCTCAGGTTACACCTTCCCAGCTGGTGTTTCTGTCCCAGG AACCTTTCTTCAGCCTACAGCTCACTCTCCAGCAGGAAACCAGGTGCAAGCTGGGAAACAGTCCCACATTCCTTACAGCCAGCAACGGCCCTCTGGACCA GGGCCAATGAACCAGGGACCTCAACAATCACAGCCACCTTCCCAGCAACCCCTTACATCTTTACCAGCTCAGCCAACAGCACAGTCTACAAGCCAGCTGC AGGTTCAAGCTCTAACTCAGCAACAACAATCCCCTACAAAAGCTGTGCCGGCTTTGGGGAAAAGCCCGCCTCACCACTCTGGATTCCAGCAGTATCAACA GGCAGATGCCTCCAAACAGCTGTGGAATCCCCCTCAGGTTCAAGGCCCATTAGGGAAAATTATGCCTGTGAAACAGCCCTACTACCTTCAGACCCAAGAC CCCATAAAACTGTTTGAGCCGTCATTGCAACCTCCTGTAATGCAGCAGCAGCCTCTAGAAAAAAAAATGAAGCCTTTTCCCATGGAGCCATATAACCATA ATCCCTCAGAAGTCAAGGTCCCAGAATTCTACTGGGATTCTTCCTACAGCATGGCTGATAACAGATCTGTAATGGCACAGCAAGCAAACATAGACCGCAG GGGCAAACGGTCACCAGGAGTCTTCCGTCCAGAGCAGGATCCTGTACCCAGAATGCCGTTTGAGAAATCCTTATTGGAGAAGCCCTCAGAGCTCATGTCA CATTCATCCTCTTTCCTGTCCCTCACCGGATTCTCTCTCAATCAGGAAAGATACCCAAATAATAGTATGTTCAATGAGGTATATGGGAAAAACCTGACAT CCAGCTCCAAAGCAGAACTCAGTCCCTCAATGGCCCCCCAGGAAACATCTCTGTATTCCCTTTTTGAAGGGACTCCGTGGTCTCCATCACTTCCTGCCAG TTCAGATCATTCAACACCAGCCAGCCAGTCTCCTCATTCCTCTAACCCAAGCAGCCTACCCAGCTCTCCTCCAACACACAACCATAATTCTGTTCCATTC TCCAATTTTGGACCCATTGGGACTCCAGATAACAGGGATAGAAGGACTGCAGATCGGTGGAAAACTGATAAGCCAGCCATGGGTGGGTTTGGCATTGATT ATCTCTCAGCAACGTCATCCTCTGAGAGCAGTTGGCATCAGGCCAGCACTCCGAGTGGCACCTGGACAGGCCATGGCCCTTCCATGGAGGATTCCTCTGC TGTCCTCATGGAAAGCCTAAAGTCTATCTGGTCCAGTTCCATGATGCATCCTGGACCTTCTGCTCTGGAGCAGCTGTTAATGCAGCAGAAGCAGAAACAG CAACGGGGACAAGGCACCATGAACCCTCCACACTGAGGCCAAAGTGGCAACCTGGGAATGAAGGCTCCATAAACCATGGCATGTTGGGTTTGCAGGACTG GCCCACACAGTCCCCTGCAGGTGGCAGCCCTCTTTTCTGTTTCTCGCTGTCAAGAGGGTGTAAGTATTCCACCAGCCCGCTGAGTGTGCACGAAATGTTC GCAGTGCAACAAAAAGAAAAATCCATCAGGAACTCTCCGTCCCCCCGGGGCCCTCCGGAGGGAGAGAGAGAGGAACTGCTGTTTATCTCACTCAGTTACT TGGTATCACCGCCTCTCACCTTCTCCATCGTGCATGTCCCCAGCCACATGGGAAGTGAAAGCTGAGAAGGGAAGGCAGATGGGAGAAGCCAATGGGAACT TCTCAGTCCTTTTTTCCTCTTTGGGGAATAAAATAGGAATCCATTAATGATTGCTTTGCTGACTGAGAATGTAGTTGAAATTATTCTTAAACATCTTTTA TTATTATTACTCTCAGTAGTAAAATATCACACTGAATTCTTCCATACACAGGTGTGCTTCTAGTCAGTGTGTAGCAAGGAAAGCCCCGTTCACTGCTCCT GTGAGAGGTTGGTGGTGACAGGATGGGGAACCGACCTCTTCAGCCAGTGGAAATGTTCCATAAGGGAGAGTTCAAGGCCTGTCAGAAGGCTCTGGTAGGC CTTCCTCTGGCCAGGAGACTCCAGCAGGGAATGCCCTTCACTCTGTAGGTGCTCGAGCCCCAATCGAGGATACAGTGTGGGTGGTGGTGCTGGGCTGGAC TAGCAGGTAGACTGCTGTAGGATTTCAAATTACGTTTTTGATTCCTGTACATTTTACAGTCGCACAGCAAGCAGTCTCACAGAAGGCAGGCTAGTCCATT CACAGCCTGACACGTTCTAATAGGTAGAAGCTTTCAGTGTGGTTATTTTTTCTTTGGTTGGTTTTTGTGCCCCCATTCTACTTCCCACCCTCCTGCCCCA TCTCCATCCCTTCTTTTACCCAATGCTGTATGCTAGTAATTGTTTTTATTCCTAATGTGTGCAACATCACATCTCCCCAAGAAGCAACAGCATGGGGTCC AGCAGTTGGGGCCCAAAAGACAGTCTGAAGAGGAAGGAAGCAGCAGTATCTGCGTAGCCCACAGAGGGCCCAGGCCCCTGCCCAGCTGCAGTCTCCCAGC CTCCACTTTCAGAGTGAAATTCAAGGCAGCACGGACATGTGCCCATCAGGCACAGAAGAAAACACGACGTCGTCCATTTTGGAAGAGACGAAAGAAAGGA AAATAAACTCTTTGTATGATATTTATTAGGAGGAAAGAGGACTGAAAATGTTCTTGTGTAGAAACAGAAGGACAGCATTTCTGTTAGTCATTTCCTGGAA AAGTAATATTTTAAGGGGAAATTATGGAAACAATCTAATTGTTCAATTGCTGTGCTAGTGGTAGGGTTTATTTTCTGGGAGGTCTCTCCTTTGTGTGTCT GTATGTTTGTGTACACACACGTGCCCATCTGCTGTCCCAGAGGGGAGGGGTTGTGTGTGCGAGTGTATGGAGTTAGTGTGGAACTTAAGAGCTGGAAGAC AGCTGTAGAGCAAAGCACATCCAGGAGCCCCAGTTGTCACTGCAGTCTGGGCAACCCCAGCAATGAAAAGGGGTGAGATAACGCTCATTGCTCTTCAGAG AGAGTGGTTGGAGCCCCCCCCGCCCCGTATGCTTACATTATTGCTCTTTTAGTTTGACATGGTGTTTGGGTTTTGTTTTTTTGAAAGGTCTGAAAAGGTG AAGCCCCCTACCCAATGGCAATATGAAACCTTTTGTGCTTCTCTTCAGCCCCTTCCCTGTGTCCACCTTTCTCTCCTCTTCCCAAGCCTTTTTCCTACTA CCTTTACCCAGTTTGTGTGTTTGAGCTCTGCATTCAGGCAGCTGCAACATTCCAGTGTTTGAACTGTCACTGATTCTTGCGCCCTAGACAAGCTAACCAG GTTTACCATCTCACTCCCAGTAATACCCAGCTCCTATCTAAAGCCCCATTCTGCATGAGAATTTGGTGTTTGGAATGTTTTCTGACTCTTGGGGCGGGAT TCCTCGCCTTATCATCCTCACTGTGGAGTAATGAGGGGGAGGAGAATCTTTATCAGAAACTGGTTTTGTGTAGTAAACTTTCTTTTGTGGTTTTTTGTTT TGTTTTCTGGGTTTTGTTTTTTGTTTTTGTCTGTGCAAGACCTGCAGCTGCTGAAAATCAGCTTTGCCTTTAATTAAACCATGTTCTCTCCAACCA

refseq_SMG7.F3 (forward primer)
refseq_SMG7.R3 (reverse primer)
Single exon skipping

Frame 0

EEPEERKMAAAASTRGAAGPLRGA*ETHGGFAG RRGGGGGG*ACRARSTSGRQKS*RLT*QILSWVQ LKSGHPGRLCRTCTRKC*LPIWNTL*TRK*NRI SGITPLRIRSQHCKARQRIEQIRIGVKFRQTFL CS*RQLVASILSYYKNCVQYLM*IYHAV*SLPNW ELSAINRRIPAP**SHSLAPVPISASTASSTLE TLLDTETRPARQSPTIGMQLSLSPPMVSLIISW LS*LLPKETI*PQFSTTAEALL*SSLSQLPPLIC KKHFLKHWKAEMR*KPSGVFLTSSRPLLNSTVM CT*VRAWKS*ALFERNWKNSLRGCYSKKLSTLS S*FMSLSLTCFNFITFVTLAMKPSSTLIAKMSSY VGHSCWPSLCLFLASCASVLYRMSLRRSPTMPI LFQQSRSPWTG*DSDPGSFRRQWWMKDSTFGPG *FLF*IVSIPMKRTSQVLVRHHFQRSLNYKDFWH *DLLSGTWIFPKVTRVLQGTKKASNDEYDSNA* SL*ANGLLIISQG*FSVKMR*GNCCLSQKSQN* YWKTPVKPKRTSFCKKHL**SRWLQMGAQG*NQC YLQAEI*ATTVTQERSQWLPSKKTLRHEK*TET KEEVFLPKR*EGTIAKE*L*LRMMERRTTTRGK LKPRNAP*KSYRKQESRMWQCR*NPRQN*ERLQC LKPEKHL*LKPQLKQVTPSSSPFITLEPSLLFP AGQGFRPQHMLSPRLWHFLWAQVTPSQLVFLSQ EPFFSLQLTLQQETRCKLGNSPTFLTASNGPLDQ GQ*TRDLNNHSHLPSNPLHLYQLSQQHSLQASC RFKL*LSNNNPLQKLCRLWGKARLTTLDSSSIN RQMPPNSCGIPLRFKAH*GKLCL*NSPTTFRPKT P*NCLSRHCNLL*CSSSL*KKK*SLFPWSHITI IPQKSRSQNSTGILPTAWLITDL*WHSKQT*TA GANGHQESSVQSRILYPECRLRNPYWRSPQSSCH IHPLSCPSPDSLSIRKDTQIIVCSMRYMGKT*H PAPKQNSVPQWPPRKHLCIPFLKGLRGLHHFLP VQIIQHQPASLLIPLTQAAYPALLQHTTIILFHS PILDPLGLQITGIEGLQIGGKLISQPWVGLALI ISQQRHPLRAVGIRPALRVAPGQAMALPWRIPL LSSWKA*SLSGPVP*CILDLLLWSSC*CSRSRNS NGDKAP*TLHTEAKVATWE*RLHKPWHVGFAGL AHTVPCRWQPSFLFLAVKRV*VFHQPAECARNV RSATKRKIHQELSVPPGPSGGRERGTAVYLTQLL GITASHLLHRACPQPHGK*KLRREGRWEKPMGT SQSFFPLWGIK*ESINDCFAD*ECS*NYS*TSF IIITLSSKISH*ILPYTGVLLVSV*QGKPRSLLL *EVGGDRMGNRPLQPVEMFHKGEFKACQKALVG LPLARRLQQGMPFTL*VLEPQSRIQCGWWCWAG LAGRLL*DFKLRF*FLYILQSHSKQSHRRQASPF TA*HVLIGRSFQCGYFFFGWFLCPHSTSHPPAP SPSLLLPNAVC**LFLFLMCATSHLPKKQQHGV QQLGPKRQSEEEGSSSICVAHRGPRPLPSCSLPA STFRVKFKAARTCAHQAQKKTRRRPFWKRRKKG K*TLCMIFIRRKED*KCSCVETEGQHFC*SFPG KVIF*GEIMETI*LFNCCASGRVYFLGGLSFVCL YVCVHTRAHLLSQRGGVVCASVWS*CGT*ELED SCRAKHIQEPQLSLQSGQPQQ*KGVR*RSLLFR ESGWSPPRPVCLHYCSFSLTWCLGFVFLKGLKR* SPLPNGNMKPFVLLFSPFPVSTFLSSSQAFFLL PLPSLCV*ALHSGSCNIPVFELSLILAP*TS*P GLPSHSQ*YPAPI*SPILHENLVFGMFSDSWGGI PRLIILTVE**GGGESLSETGFV**TFFCGFLF CFLGFVFCFCLCKTCSC*KSALPLIKPCSLQP

Frame 1

RSRRRGRWRRPPAPAVPRGRSEEPERPTEASRE DAAAAAEDEPAERAVPPAGRSPEG*HDRF*AGS S*SLDIQAGSAGPVPENASYRFGIRFRQESRTGS LESRL*ESDHNTARPGKESSKSESE*SSGKPFS VPRGS*WLLYSVITRTVYSI*CRFTMPCEVFPI GNYQQ*TDAYQRHSEATV*LLFLYLPALPRPPWR HCSIQKPDQPGRVLL*ACSSACPLQWSAL*SVG YLSFFQRRPSDHNFLLLQKHCCEVPFPSCLH*S AKSTF*STGKPR*GENQVGCF*LHQGLY*IPRSC VPE*ELGKVEPSSREIGRTV*EAAIPKSFQLSA VSSCHCH*PVSTSSPS*L*Q*NRAAHL*PR*AA MLDTVAGPLYVFSWHPVQVSSTE*VSGGVLQCLS SSSSQGLHGLAKTQTQGLSGGSGG*KTVHLALV DFSSE*FPSP*RGPLKY*CDTTSRGV*ITRIFG IETFFQELGFFQRSPGYYRGQRRPATTNTTATLD LYRQMDC**SAKADSV*K*GREIVVYHRNPRIN TGRPQ*SQREPHSARNICDRVAGCRWEPRAKIS AIYKPKFKQQL*HRREASGYLQRKH*DTRSEQRP RKKFSSQRGEKGL*QRNNCN*E*WKEGQQQEEN *NQEMHLRKVTGNRKAECGSAGKIPDRTKKDSS V*SQKNTCNSNPNSSK*LPVHPHSSPWSLPSSSQ QARVSAPNICYPPACGIFYGLRLHLPSWCFCPR NLSSAYSSLSSRKPGASWETVPHSLQPATALWT RANEPGTSTITATFPATPYIFTSSANSTVYKPAA GSSSNSATTIPYKSCAGFGEKPASPLWIPAVST GRCLQTAVESPSGSRPIRENYACETALLPSDPR PHKTV*AVIATSCNAAAASRKKNEAFSHGAI*P* SLRSQGPRILLGFFLQHG**QICNGTASKHRPQ GQTVTRSLPSRAGSCTQNAV*EILIGEALRAHV TFILFPVPHRILSQSGKIPK**YVQ*GIWEKPDI QLQSRTQSLNGPPGNISVFPF*RDSVVSITSCQ FRSFNTSQPVSSFL*PKQPTQLSSNTQP*FCSI LQFWTHWDSR*QG*KDCRSVEN**ASHGWVWH*L SLSNVIL*EQLASGQHSEWHLDRPWPFHGGFLC CPHGKPKVYLVQFHDASWTFCSGAAVNAAEAET ATGTRHHEPSTLRPKWQPGNEGSINHGMLGLQDW PTQSPAGGSPLFCFSLSRGCKYSTSPLSVHEMF AVQQKEKSIRNSPSPRGPPEGEREELLFISLSY LVSPPLTFSIVHVPSHMGSES*EGKADGRSQWEL LSPFFLFGE*NRNPLMIALLTENVVEIILKHLL LLLLSVVKYHTEFFHTQVCF*SVCSKESPVHCS CERLVVTGWGTDLFSQWKCSIRESSRPVRRLW*A FLWPGDSSRECPSLCRCSSPNRGYSVGGGAGLD *QVDCCRISNYVFDSCTFYSRTASSLTEGRLVH SQPDTF**VEAFSVVIFSLVGFCAPILLPTLLPH LHPFFYPMLYASNCFYS*CVQHHISPRSNSMGS SSWGPKDSLKRKEAAVSA*PTEGPGPCPAAVSQ PPLSE*NSRQHGHVPIRHRRKHDVVHFGRDERKE NKLFV*YLLGGKRTENVLV*KQKDSISVSHFLE K*YFKGKLWKQSNCSIAVLVVGFIFWEVSPLCV CMFVYTHVPICCPRGEGLCVRVYGVSVELKSWKT AVEQSTSRSPSCHCSLGNPSNEKG*DNAHCSSE RVVGAPPAPYAYIIALLV*HGVWVLFF*KV*KG EAPYPMAI*NLLCFSSAPSLCPPFSPLPKPFSYY LYPVCVFELCIQAAATFQCLNCH*FLRPRQANQ VYHLTPSNTQLLSKAPFCMRIWCLECFLTLGAG FLALSSSLWSNEGEENLYQKLVLCSKLSFVVFCF VFWVLFFVFVCARPAAAENQLCL*LNHVLSN

Frame 2

GAGGEEDGGGRQHPRCRGAAPRSLRDPRRLRGK TRRRRRRMSLQSAQYLRQAEVLKADMTDSKLGP AEVWTSRQALQDLYQKMLVTDLEYALDKKVEQD LWNHAFKNQITTLQGQAKNRANPNRSEVQANLSL FLEAASGFYTQLLQELCTVFNVDLPCRVKSSQL GIISNKQTHTSAIVKPQSSSCSYICQHCLVHLG DIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLA ILASSKGDHLTTIFYYCRSIAVKFPFPAASTNL QKALSKALESRDEVKTKWGVSDFIKAFIKFHGH VYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQ LVHVTVINLFQLHHLRDFSNETEQHTYSQDEQL CWTQLLALFMSFLGILCKCPLQNESQEESYNAY PLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWL ISLLNSFHPHEEDLSSISATPLPEEFELQGFLA LRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRL ISIGKWIADNQPRLIQCENEVGKLLFITEIPELI LEDPSEAKENLILQETSVIESLAADGSPGLKSV LSTSRNLSNNCDTGEKPVVTFKENIKTREVNRD QGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKT ETKKCTLEKLQETGKQNVAVQVKSQTELRKTPV SEARKTPVTQTPTQASNSQFIPIHHPGAFPPLP SRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPG TFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGP GPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQL QVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQ ADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNH NPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRR GKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMS HSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLT SSSKAELSPSMAPQETSLYSLFEGTPWSPSLPAS SDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPF SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGID YLSATSSSESSWHQASTPSGTWTGHGPSMEDSSA VLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ QRGQGTMNPPH*GQSGNLGMKAP*TMACWVCRT GPHSPLQVAALFSVSRCQEGVSIPPAR*VCTKCS QCNKKKNPSGTLRPPGALRRERERNCCLSHSVT WYHRLSPSPSCMSPATWEVKAEKGRQMGEANGN FSVLFSSLGNKIGIH**LLC*LRM*LKLFLNIFY YYYSQ**NITLNSSIHRCASSQCVARKAPFTAP VRGWW*QDGEPTSSASGNVP*GRVQGLSEGSGR PSSGQETPAGNALHSVGARAPIEDTVWVVVLGWT SR*TAVGFQITFLIPVHFTVAQQAVSQKAG*SI HSLTRSNR*KLSVWLFFLWLVFVPPFYFPPSCP ISIPSFTQCCMLVIVFIPNVCNITSPQEATAWGP AVGAQKTV*RGRKQQYLRSPQRAQAPAQLQSPS LHFQSEIQGSTDMCPSGTEENTTSSILEETKER KINSLYDIY*EERGLKMFLCRNRRTAFLLVISWK SNILRGNYGNNLIVQLLC*W*GLFSGRSLLCVS VCLCTHTCPSAVPEGRGCVCECMELVWNLRAGR QL*SKAHPGAPVVTAVWATPAMKRGEITLIALQR EWLEPPPPRMLTLLLF*FDMVFGFCFFERSEKV KPPTQWQYETFCASLQPLPCVHLSLLFPSLFPT TFTQFVCLSSAFRQLQHSSV*TVTDSCALDKLTR FTISLPVIPSSYLKPHSA*EFGVWNVF*LLGRD SSPYHPHCGVMRGRRIFIRNWFCVVNFLLWFFV LFSGFCFLFLSVQDLQLLKISFAFN*TMFSPT

Sequence NM_014837

GAGGAGCCGGAGGAGAGGAAGATGGCGGCGGCCGCCAGCACCCGCGGTGCCGCGGGGCCGCTCCGAGGAGCCTGAGAGACCCACGGAGGCTTCGCGGGAA GACGCGGCGGCGGCGGCGGAGGATGAGCCTGCAGAGCGCGCAGTACCTCCGGCAGGCAGAAGTCCTGAAGGCTGACATGACAGATTCTAAGCTGGGTCCA GCTGAAGTCTGGACATCCAGGCAGGCTCTGCAGGACCTGTACCAGAAAATGCTAGTTACCGATTTGGAATACGCTTTAGACAAGAAAGTAGAACAGGATC TCTGGAATCACGCCTTTAAGAATCAGATCACAACACTGCAAGGCCAGGCAAAGAATCGAGCAAATCCGAATCGGAGTGAAGTTCAGGCAAACCTTTCTCT GTTCCTAGAGGCAGCTAGTGGCTTCTATACTCAGTTATTACAAGAACTGTGTACAGTATTTAATGTAGATTTACCATGCCGTGTGAAGTCTTCCCAATTG GGAATTATCAGCAATAAACAGACGCATACCAGCGCCATAGTGAAGCCACAGTCTAGCTCCTGTTCCTATATCTGCCAGCACTGCCTCGTCCACCTTGGAG ACATTGCTCGATACAGAAACCAGACCAGCCAGGCAGAGTCCTACTATAGGCATGCAGCTCAGCTTGTCCCCTCCAATGGTCAGCCTTATAATCAGTTGGC TATCTTAGCTTCTTCCAAAGGAGACCATCTGACCACAATTTTCTACTACTGCAGAAGCATTGCTGTGAAGTTCCCTTTCCCAGCTGCCTCCACTAATCTG CAAAAAGCACTTTCTAAAGCACTGGAAAGCCGAGATGAGGTGAAAACCAAGTGGGGTGTTTCTGACTTCATCAAGGCCTTTATTAAATTCCACGGTCATG TGTACCTGAGTAAGAGCTTGGAAAAGTTGAGCCCTCTTCGAGAGAAATTGGAAGAACAGTTTAAGAGGCTGCTATTCCAAAAAGCTTTCAACTCTCAGCA GTTAGTTCATGTCACTGTCATTAACCTGTTTCAACTTCATCACCTTCGTGACTTTAGCAATGAAACCGAGCAGCACACTTATAGCCAAGATGAGCAGCTA TGTTGGACACAGTTGCTGGCCCTCTTTATGTCTTTTCTTGGCATCCTGTGCAAGTGTCCTCTACAGAATGAGTCTCAGGAGGAGTCCTACAATGCCTATC CTCTTCCAGCAGTCAAGGTCTCCATGGACTGGCTAAGACTCAGACCCAGGGTCTTTCAGGAGGCAGTGGTGGATGAAAGACAGTACATTTGGCCCTGGTT GATTTCTCTTCTGAATAGTTTCCATCCCCATGAAGAGGACCTCTCAAGTATTAGTGCGACACCACTTCCAGAGGAGTTTGAATTACAAGGATTTTTGGCA TTGAGACCTTCTTTCAGGAACTTGGATTTTTCCAAAGGTCACCAGGGTATTACAGGGGACAAAGAAGGCCAGCAACGACGAATACGACAGCAACGCTTGA TCTCTATAGGCAAATGGATTGCTGATAATCAGCCAAGGCTGATTCAGTGTGAAAATGAGGTAGGGAAATTGTTGTTTATCACAGAAATCCCAGAATTAAT ACTGGAAGACCCCAGTGAAGCCAAAGAGAACCTCATTCTGCAAGAAACATCTGTGATAGAGTCGCTGGCTGCAGATGGGAGCCCAGGGCTAAAATCAGTG CTATCTACAAGCCGAAATTTAAGCAACAACTGTGACACAGGAGAGAAGCCAGTGGTTACCTTCAAAGAAAACATTAAGACACGAGAAGTGAACAGAGACC AAGGAAGAAGTTTTCCTCCCAAAGTAACTCAAACCCCAACTCAAGCAAGTAACTCCCAGTTCATCCCCATTCATCACCCTGGAGCCTTCCCTCCTCTTCC CAGCAGGCCAGGGTTTCCGCCCCCAACATATGTTATCCCCCCGCCTGTGGCATTTTCTATGGGCTCAGGTTACACCTTCCCAGCTGGTGTTTCTGTCCCA GGAACCTTTCTTCAGCCTACAGCTCACTCTCCAGCAGGAAACCAGGTGCAAGCTGGGAAACAGTCCCACATTCCTTACAGCCAGCAACGGCCCTCTGGAC CAGGGCCAATGAACCAGGGACCTCAACAATCACAGCCACCTTCCCAGCAACCCCTTACATCTTTACCAGCTCAGCCAACAGCACAGTCTACAAGCCAGCT GCAGGTTCAAGCTCTAACTCAGCAACAACAATCCCCTACAAAAGCTGTGCCGGCTTTGGGGAAAAGCCCGCCTCACCACTCTGGATTCCAGCAGTATCAA CAGGCAGATGCCTCCAAACAGCTGTGGAATCCCCCTCAGGTTCAAGGCCCATTAGGGAAAATTATGCCTGTGAAACAGCCCTACTACCTTCAGACCCAAG ACCCCATAAAACTGTTTGAGCCGTCATTGCAACCTCCTGTAATGCAGCAGCAGCCTCTAGAAAAAAAAATGAAGCCTTTTCCCATGGAGCCATATAACCA TAATCCCTCAGAAGTCAAGGTCCCAGAATTCTACTGGGATTCTTCCTACAGCATGGCTGATAACAGATCTGTAATGGCACAGCAAGCAAACATAGACCGC AGGGGCAAACGGTCACCAGGAGTCTTCCGTCCAGAGCAGGATCCTGTACCCAGAATGCCGTTTGAGAAATCCTTATTGGAGAAGCCCTCAGAGCTCATGT CACATTCATCCTCTTTCCTGTCCCTCACCGGATTCTCTCTCAATCAGGAAAGATACCCAAATAATAGTATGTTCAATGAGGTATATGGGAAAAACCTGAC ATCCAGCTCCAAAGCAGAACTCAGTCCCTCAATGGCCCCCCAGGAAACATCTCTGTATTCCCTTTTTGAAGGGACTCCGTGGTCTCCATCACTTCCTGCC AGTTCAGATCATTCAACACCAGCCAGCCAGTCTCCTCATTCCTCTAACCCAAGCAGCCTACCCAGCTCTCCTCCAACACACAACCATAATTCTGTTCCAT TCTCCAATTTTGGACCCATTGGGACTCCAGATAACAGGGATAGAAGGACTGCAGATCGGTGGAAAACTGATAAGCCAGCCATGGGTGGGTTTGGCATTGA TTATCTCTCAGCAACGTCATCCTCTGAGAGCAGTTGGCATCAGGCCAGCACTCCGAGTGGCACCTGGACAGGCCATGGCCCTTCCATGGAGGATTCCTCT GCTGTCCTCATGGAAAGCCTAAAGTCTATCTGGTCCAGTTCCATGATGCATCCTGGACCTTCTGCTCTGGAGCAGCTGTTAATGCAGCAGAAGCAGAAAC AGCAACGGGGACAAGGCACCATGAACCCTCCACACTGAGGCCAAAGTGGCAACCTGGGAATGAAGGCTCCATAAACCATGGCATGTTGGGTTTGCAGGAC TGGCCCACACAGTCCCCTGCAGGTGGCAGCCCTCTTTTCTGTTTCTCGCTGTCAAGAGGGTGTAAGTATTCCACCAGCCCGCTGAGTGTGCACGAAATGT TCGCAGTGCAACAAAAAGAAAAATCCATCAGGAACTCTCCGTCCCCCCGGGGCCCTCCGGAGGGAGAGAGAGAGGAACTGCTGTTTATCTCACTCAGTTA CTTGGTATCACCGCCTCTCACCTTCTCCATCGTGCATGTCCCCAGCCACATGGGAAGTGAAAGCTGAGAAGGGAAGGCAGATGGGAGAAGCCAATGGGAA CTTCTCAGTCCTTTTTTCCTCTTTGGGGAATAAAATAGGAATCCATTAATGATTGCTTTGCTGACTGAGAATGTAGTTGAAATTATTCTTAAACATCTTT TATTATTATTACTCTCAGTAGTAAAATATCACACTGAATTCTTCCATACACAGGTGTGCTTCTAGTCAGTGTGTAGCAAGGAAAGCCCCGTTCACTGCTC CTGTGAGAGGTTGGTGGTGACAGGATGGGGAACCGACCTCTTCAGCCAGTGGAAATGTTCCATAAGGGAGAGTTCAAGGCCTGTCAGAAGGCTCTGGTAG GCCTTCCTCTGGCCAGGAGACTCCAGCAGGGAATGCCCTTCACTCTGTAGGTGCTCGAGCCCCAATCGAGGATACAGTGTGGGTGGTGGTGCTGGGCTGG ACTAGCAGGTAGACTGCTGTAGGATTTCAAATTACGTTTTTGATTCCTGTACATTTTACAGTCGCACAGCAAGCAGTCTCACAGAAGGCAGGCTAGTCCA TTCACAGCCTGACACGTTCTAATAGGTAGAAGCTTTCAGTGTGGTTATTTTTTCTTTGGTTGGTTTTTGTGCCCCCATTCTACTTCCCACCCTCCTGCCC CATCTCCATCCCTTCTTTTACCCAATGCTGTATGCTAGTAATTGTTTTTATTCCTAATGTGTGCAACATCACATCTCCCCAAGAAGCAACAGCATGGGGT CCAGCAGTTGGGGCCCAAAAGACAGTCTGAAGAGGAAGGAAGCAGCAGTATCTGCGTAGCCCACAGAGGGCCCAGGCCCCTGCCCAGCTGCAGTCTCCCA GCCTCCACTTTCAGAGTGAAATTCAAGGCAGCACGGACATGTGCCCATCAGGCACAGAAGAAAACACGACGTCGTCCATTTTGGAAGAGACGAAAGAAAG GAAAATAAACTCTTTGTATGATATTTATTAGGAGGAAAGAGGACTGAAAATGTTCTTGTGTAGAAACAGAAGGACAGCATTTCTGTTAGTCATTTCCTGG AAAAGTAATATTTTAAGGGGAAATTATGGAAACAATCTAATTGTTCAATTGCTGTGCTAGTGGTAGGGTTTATTTTCTGGGAGGTCTCTCCTTTGTGTGT CTGTATGTTTGTGTACACACACGTGCCCATCTGCTGTCCCAGAGGGGAGGGGTTGTGTGTGCGAGTGTATGGAGTTAGTGTGGAACTTAAGAGCTGGAAG ACAGCTGTAGAGCAAAGCACATCCAGGAGCCCCAGTTGTCACTGCAGTCTGGGCAACCCCAGCAATGAAAAGGGGTGAGATAACGCTCATTGCTCTTCAG AGAGAGTGGTTGGAGCCCCCCCCGCCCCGTATGCTTACATTATTGCTCTTTTAGTTTGACATGGTGTTTGGGTTTTGTTTTTTTGAAAGGTCTGAAAAGG TGAAGCCCCCTACCCAATGGCAATATGAAACCTTTTGTGCTTCTCTTCAGCCCCTTCCCTGTGTCCACCTTTCTCTCCTCTTCCCAAGCCTTTTTCCTAC TACCTTTACCCAGTTTGTGTGTTTGAGCTCTGCATTCAGGCAGCTGCAACATTCCAGTGTTTGAACTGTCACTGATTCTTGCGCCCTAGACAAGCTAACC AGGTTTACCATCTCACTCCCAGTAATACCCAGCTCCTATCTAAAGCCCCATTCTGCATGAGAATTTGGTGTTTGGAATGTTTTCTGACTCTTGGGGCGGG ATTCCTCGCCTTATCATCCTCACTGTGGAGTAATGAGGGGGAGGAGAATCTTTATCAGAAACTGGTTTTGTGTAGTAAACTTTCTTTTGTGGTTTTTTGT TTTGTTTTCTGGGTTTTGTTTTTTGTTTTTGTCTGTGCAAGACCTGCAGCTGCTGAAAATCAGCTTTGCCTTTAATTAAACCATGTTCTCTCCAACCA

refseq_SMG7.F3 (forward primer)
refseq_SMG7.R3 (reverse primer)
Single exon skipping

Frame 0

EEPEERKMAAAASTRGAAGPLRGA*ETHGGFAG RRGGGGGG*ACRARSTSGRQKS*RLT*QILSWVQ LKSGHPGRLCRTCTRKC*LPIWNTL*TRK*NRI SGITPLRIRSQHCKARQRIEQIRIGVKFRQTFL CS*RQLVASILSYYKNCVQYLM*IYHAV*SLPNW ELSAINRRIPAP**SHSLAPVPISASTASSTLE TLLDTETRPARQSPTIGMQLSLSPPMVSLIISW LS*LLPKETI*PQFSTTAEALL*SSLSQLPPLIC KKHFLKHWKAEMR*KPSGVFLTSSRPLLNSTVM CT*VRAWKS*ALFERNWKNSLRGCYSKKLSTLS S*FMSLSLTCFNFITFVTLAMKPSSTLIAKMSSY VGHSCWPSLCLFLASCASVLYRMSLRRSPTMPI LFQQSRSPWTG*DSDPGSFRRQWWMKDSTFGPG *FLF*IVSIPMKRTSQVLVRHHFQRSLNYKDFWH *DLLSGTWIFPKVTRVLQGTKKASNDEYDSNA* SL*ANGLLIISQG*FSVKMR*GNCCLSQKSQN* YWKTPVKPKRTSFCKKHL**SRWLQMGAQG*NQC YLQAEI*ATTVTQERSQWLPSKKTLRHEK*TET KEEVFLPK*LKPQLKQVTPSSSPFITLEPSLLF PAGQGFRPQHMLSPRLWHFLWAQVTPSQLVFLSQ EPFFSLQLTLQQETRCKLGNSPTFLTASNGPLD QGQ*TRDLNNHSHLPSNPLHLYQLSQQHSLQAS CRFKL*LSNNNPLQKLCRLWGKARLTTLDSSSIN RQMPPNSCGIPLRFKAH*GKLCL*NSPTTFRPK TP*NCLSRHCNLL*CSSSL*KKK*SLFPWSHIT IIPQKSRSQNSTGILPTAWLITDL*WHSKQT*TA GANGHQESSVQSRILYPECRLRNPYWRSPQSSC HIHPLSCPSPDSLSIRKDTQIIVCSMRYMGKT* HPAPKQNSVPQWPPRKHLCIPFLKGLRGLHHFLP VQIIQHQPASLLIPLTQAAYPALLQHTTIILFH SPILDPLGLQITGIEGLQIGGKLISQPWVGLAL IISQQRHPLRAVGIRPALRVAPGQAMALPWRIPL LSSWKA*SLSGPVP*CILDLLLWSSC*CSRSRN SNGDKAP*TLHTEAKVATWE*RLHKPWHVGFAG LAHTVPCRWQPSFLFLAVKRV*VFHQPAECARNV RSATKRKIHQELSVPPGPSGGRERGTAVYLTQL LGITASHLLHRACPQPHGK*KLRREGRWEKPMG TSQSFFPLWGIK*ESINDCFAD*ECS*NYS*TSF IIITLSSKISH*ILPYTGVLLVSV*QGKPRSLL L*EVGGDRMGNRPLQPVEMFHKGEFKACQKALV GLPLARRLQQGMPFTL*VLEPQSRIQCGWWCWAG LAGRLL*DFKLRF*FLYILQSHSKQSHRRQASP FTA*HVLIGRSFQCGYFFFGWFLCPHSTSHPPA PSPSLLLPNAVC**LFLFLMCATSHLPKKQQHGV QQLGPKRQSEEEGSSSICVAHRGPRPLPSCSLP ASTFRVKFKAARTCAHQAQKKTRRRPFWKRRKK GK*TLCMIFIRRKED*KCSCVETEGQHFC*SFPG KVIF*GEIMETI*LFNCCASGRVYFLGGLSFVC LYVCVHTRAHLLSQRGGVVCASVWS*CGT*ELE DSCRAKHIQEPQLSLQSGQPQQ*KGVR*RSLLFR ESGWSPPRPVCLHYCSFSLTWCLGFVFLKGLKR *SPLPNGNMKPFVLLFSPFPVSTFLSSSQAFFL LPLPSLCV*ALHSGSCNIPVFELSLILAP*TS*P GLPSHSQ*YPAPI*SPILHENLVFGMFSDSWGG IPRLIILTVE**GGGESLSETGFV**TFFCGFL FCFLGFVFCFCLCKTCSC*KSALPLIKPCSLQP

Frame 1

RSRRRGRWRRPPAPAVPRGRSEEPERPTEASRE DAAAAAEDEPAERAVPPAGRSPEG*HDRF*AGS S*SLDIQAGSAGPVPENASYRFGIRFRQESRTGS LESRL*ESDHNTARPGKESSKSESE*SSGKPFS VPRGS*WLLYSVITRTVYSI*CRFTMPCEVFPI GNYQQ*TDAYQRHSEATV*LLFLYLPALPRPPWR HCSIQKPDQPGRVLL*ACSSACPLQWSAL*SVG YLSFFQRRPSDHNFLLLQKHCCEVPFPSCLH*S AKSTF*STGKPR*GENQVGCF*LHQGLY*IPRSC VPE*ELGKVEPSSREIGRTV*EAAIPKSFQLSA VSSCHCH*PVSTSSPS*L*Q*NRAAHL*PR*AA MLDTVAGPLYVFSWHPVQVSSTE*VSGGVLQCLS SSSSQGLHGLAKTQTQGLSGGSGG*KTVHLALV DFSSE*FPSP*RGPLKY*CDTTSRGV*ITRIFG IETFFQELGFFQRSPGYYRGQRRPATTNTTATLD LYRQMDC**SAKADSV*K*GREIVVYHRNPRIN TGRPQ*SQREPHSARNICDRVAGCRWEPRAKIS AIYKPKFKQQL*HRREASGYLQRKH*DTRSEQRP RKKFSSQSNSNPNSSK*LPVHPHSSPWSLPSSS QQARVSAPNICYPPACGIFYGLRLHLPSWCFCP RNLSSAYSSLSSRKPGASWETVPHSLQPATALWT RANEPGTSTITATFPATPYIFTSSANSTVYKPA AGSSSNSATTIPYKSCAGFGEKPASPLWIPAVS TGRCLQTAVESPSGSRPIRENYACETALLPSDPR PHKTV*AVIATSCNAAAASRKKNEAFSHGAI*P *SLRSQGPRILLGFFLQHG**QICNGTASKHRP QGQTVTRSLPSRAGSCTQNAV*EILIGEALRAHV TFILFPVPHRILSQSGKIPK**YVQ*GIWEKPD IQLQSRTQSLNGPPGNISVFPF*RDSVVSITSC QFRSFNTSQPVSSFL*PKQPTQLSSNTQP*FCSI LQFWTHWDSR*QG*KDCRSVEN**ASHGWVWH* LSLSNVIL*EQLASGQHSEWHLDRPWPFHGGFL CCPHGKPKVYLVQFHDASWTFCSGAAVNAAEAET ATGTRHHEPSTLRPKWQPGNEGSINHGMLGLQD WPTQSPAGGSPLFCFSLSRGCKYSTSPLSVHEM FAVQQKEKSIRNSPSPRGPPEGEREELLFISLSY LVSPPLTFSIVHVPSHMGSES*EGKADGRSQWE LLSPFFLFGE*NRNPLMIALLTENVVEIILKHL LLLLLSVVKYHTEFFHTQVCF*SVCSKESPVHCS CERLVVTGWGTDLFSQWKCSIRESSRPVRRLW* AFLWPGDSSRECPSLCRCSSPNRGYSVGGGAGL D*QVDCCRISNYVFDSCTFYSRTASSLTEGRLVH SQPDTF**VEAFSVVIFSLVGFCAPILLPTLLP HLHPFFYPMLYASNCFYS*CVQHHISPRSNSMG SSSWGPKDSLKRKEAAVSA*PTEGPGPCPAAVSQ PPLSE*NSRQHGHVPIRHRRKHDVVHFGRDERK ENKLFV*YLLGGKRTENVLV*KQKDSISVSHFL EK*YFKGKLWKQSNCSIAVLVVGFIFWEVSPLCV CMFVYTHVPICCPRGEGLCVRVYGVSVELKSWK TAVEQSTSRSPSCHCSLGNPSNEKG*DNAHCSS ERVVGAPPAPYAYIIALLV*HGVWVLFF*KV*KG EAPYPMAI*NLLCFSSAPSLCPPFSPLPKPFSY YLYPVCVFELCIQAAATFQCLNCH*FLRPRQAN QVYHLTPSNTQLLSKAPFCMRIWCLECFLTLGAG FLALSSSLWSNEGEENLYQKLVLCSKLSFVVFC FVFWVLFFVFVCARPAAAENQLCL*LNHVLSN

Frame 2

GAGGEEDGGGRQHPRCRGAAPRSLRDPRRLRGK TRRRRRRMSLQSAQYLRQAEVLKADMTDSKLGP AEVWTSRQALQDLYQKMLVTDLEYALDKKVEQD LWNHAFKNQITTLQGQAKNRANPNRSEVQANLSL FLEAASGFYTQLLQELCTVFNVDLPCRVKSSQL GIISNKQTHTSAIVKPQSSSCSYICQHCLVHLG DIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLA ILASSKGDHLTTIFYYCRSIAVKFPFPAASTNL QKALSKALESRDEVKTKWGVSDFIKAFIKFHGH VYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQ LVHVTVINLFQLHHLRDFSNETEQHTYSQDEQL CWTQLLALFMSFLGILCKCPLQNESQEESYNAY PLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWL ISLLNSFHPHEEDLSSISATPLPEEFELQGFLA LRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRL ISIGKWIADNQPRLIQCENEVGKLLFITEIPELI LEDPSEAKENLILQETSVIESLAADGSPGLKSV LSTSRNLSNNCDTGEKPVVTFKENIKTREVNRD QGRSFPPKVTQTPTQASNSQFIPIHHPGAFPPLP SRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVP GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSG PGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQL QVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQ QADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQ DPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNH NPSEVKVPEFYWDSSYSMADNRSVMAQQANIDR RGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELM SHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLT SSSKAELSPSMAPQETSLYSLFEGTPWSPSLPA SSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVP FSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGID YLSATSSSESSWHQASTPSGTWTGHGPSMEDSS AVLMESLKSIWSSSMMHPGPSALEQLLMQQKQK QQRGQGTMNPPH*GQSGNLGMKAP*TMACWVCRT GPHSPLQVAALFSVSRCQEGVSIPPAR*VCTKC SQCNKKKNPSGTLRPPGALRRERERNCCLSHSV TWYHRLSPSPSCMSPATWEVKAEKGRQMGEANGN FSVLFSSLGNKIGIH**LLC*LRM*LKLFLNIF YYYYSQ**NITLNSSIHRCASSQCVARKAPFTA PVRGWW*QDGEPTSSASGNVP*GRVQGLSEGSGR PSSGQETPAGNALHSVGARAPIEDTVWVVVLGW TSR*TAVGFQITFLIPVHFTVAQQAVSQKAG*S IHSLTRSNR*KLSVWLFFLWLVFVPPFYFPPSCP ISIPSFTQCCMLVIVFIPNVCNITSPQEATAWG PAVGAQKTV*RGRKQQYLRSPQRAQAPAQLQSP SLHFQSEIQGSTDMCPSGTEENTTSSILEETKER KINSLYDIY*EERGLKMFLCRNRRTAFLLVISW KSNILRGNYGNNLIVQLLC*W*GLFSGRSLLCV SVCLCTHTCPSAVPEGRGCVCECMELVWNLRAGR QL*SKAHPGAPVVTAVWATPAMKRGEITLIALQ REWLEPPPPRMLTLLLF*FDMVFGFCFFERSEK VKPPTQWQYETFCASLQPLPCVHLSLLFPSLFPT TFTQFVCLSSAFRQLQHSSV*TVTDSCALDKLT RFTISLPVIPSSYLKPHSA*EFGVWNVF*LLGR DSSPYHPHCGVMRGRRIFIRNWFCVVNFLLWFFV LFSGFCFLFLSVQDLQLLKISFAFN*TMFSPT