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Sequence NM_004011
TAATGAGATCAGGAGGAACATTCGACCTGAGAAAGACAGATTGCAATGACTGAGATGATTTTGCTAATTTTTTTTCCAGCCTATTTCCTTAATGCTGTAAGGAGGCAAAAGTTGCTTGAACAGAGCATCCAGTCTGCCCAGGAGACTGAAAAATCCTTACACTTAATCCAGGAGTCCCTCACATTCATTGACAAGCAGTT
GGCAGCTTATATTGCAGACAAGGTGGACGCAGCTCAAATGCCTCAGGAAGCCCAGAAAATCCAATCTGATTTGACAAGTCATGAGATCAGTTTAGAAGAA
ATGAAGAAACATAATCAGGGGAAGGAGGCTGCCCAAAGAGTCCTGTCTCAGATTGATGTTGCACAGAAAAAATTACAAGATGTCTCCATGAAGTTTCGAT
TATTCCAGAAACCAGCCAATTTTGAGCAGCGTCTACAAGAAAGTAAGATGATTTTAGATGAAGTGAAGATGCACTTGCCTGCATTGGAAACAAAGAGTGT
GGAACAGGAAGTAGTACAGTCACAGCTAAATCATTGTGTGAACTTGTATAAAAGTCTGAGTGAAGTGAAGTCTGAAGTGGAAATGGTGATAAAGACTGGA
CGTCAGATTGTACAGAAAAAGCAGACGGAAAATCCCAAAGAACTTGATGAAAGAGTAACAGCTTTGAAATTGCATTATAATGAGCTGGGAGCAAAGGTAA
CAGAAAGAAAGCAACAGTTGGAGAAATGCTTGAAATTGTCCCGTAAGATGCGAAAGGAAATGAATGTCTTGACAGAATGGCTGGCAGCTACAGATATGGA
ATTGACAAAGAGATCAGCAGTTGAAGGAATGCCTAGTAATTTGGATTCTGAAGTTGCCTGGGGAAAGGCTACTCAAAAAGAGATTGAGAAACAGAAGGTG
CACCTGAAGAGTATCACAGAGGTAGGAGAGGCCTTGAAAACAGTTTTGGGCAAGAAGGAGACGTTGGTGGAAGATAAACTCAGTCTTCTGAATAGTAACT
GGATAGCTGTCACCTCCCGAGCAGAAGAGTGGTTAAATCTTTTGTTGGAATACCAGAAACACATGGAAACTTTTGACCAGAATGTGGACCACATCACAAA
GTGGATCATTCAGGCTGACACACTTTTGGATGAATCAGAGAAAAAGAAACCCCAGCAAAAAGAAGACGTGCTTAAGCGTTTAAAGGCAGAACTGAATGAC
ATACGCCCAAAGGTGGACTCTACACGTGACCAAGCAGCAAACTTGATGGCAAACCGCGGTGACCACTGCAGGAAATTAGTAGAGCCCCAAATCTCAGAGC
TCAACCATCGATTTGCAGCCATTTCACACAGAATTAAGACTGGAAAGGCCTCCATTCCTTTGAAGGAATTGGAGCAGTTTAACTCAGATATACAAAAATT
GCTTGAACCACTGGAGGCTGAAATTCAGCAGGGGGTGAATCTGAAAGAGGAAGACTTCAATAAAGATATGAATGAAGACAATGAGGGTACTGTAAAAGAA
TTGTTGCAAAGAGGAGACAACTTACAACAAAGAATCACAGATGAGAGAAAGCGAGAGGAAATAAAGATAAAACAGCAGCTGTTACAGACAAAACATAATG
CTCTCAAGGATTTGAGGTCTCAAAGAAGAAAAAAGGCTCTAGAAATTTCTCATCAGTGGTATCAGTACAAGAGGCAGGCTGATGATCTCCTGAAATGCTT
GGATGACATTGAAAAAAAATTAGCCAGCCTACCTGAGCCCAGAGATGAAAGGAAAATAAAGGAAATTGATCGGGAATTGCAGAAGAAGAAAGAGGAGCTG
AATGCAGTGCGTAGGCAAGCTGAGGGCTTGTCTGAGGATGGGGCCGCAATGGCAGTGGAGCCAACTCAGATCCAGCTCAGCAAGCGCTGGCGGGAAATTG
AGAGCAAATTTGCTCAGTTTCGAAGACTCAACTTTGCACAAATTCACACTGTCCGTGAAGAAACGATGATGGTGATGACTGAAGACATGCCTTTGGAAAT
TTCTTATGTGCCTTCTACTTATTTGACTGAAATCACTCATGTCTCACAAGCCCTATTAGAAGTGGAACAACTTCTCAATGCTCCTGACCTCTGTGCTAAG
GACTTTGAAGATCTCTTTAAGCAAGAGGAGTCTCTGAAGAATATAAAAGATAGTCTACAACAAAGCTCAGGTCGGATTGACATTATTCATAGCAAGAAGA
CAGCAGCATTGCAAAGTGCAACGCCTGTGGAAAGGGTGAAGCTACAGGAAGCTCTCTCCCAGCTTGATTTCCAATGGGAAAAAGTTAACAAAATGTACAA
GGACCGACAAGGGCGATTTGACAGATCTGTTGAGAAATGGCGGCGTTTTCATTATGATATAAAGATATTTAATCAGTGGCTAACAGAAGCTGAACAGTTT
CTCAGAAAGACACAAATTCCTGAGAATTGGGAACATGCTAAATACAAATGGTATCTTAAGGAACTCCAGGATGGCATTGGGCAGCGGCAAACTGTTGTCA
GAACATTGAATGCAACTGGGGAAGAAATAATTCAGCAATCCTCAAAAACAGATGCCAGTATTCTACAGGAAAAATTGGGAAGCCTGAATCTGCGGTGGCA
GGAGGTCTGCAAACAGCTGTCAGACAGAAAAAAGAGGCTAGAAGAACAAAAGAATATCTTGTCAGAATTTCAAAGAGATTTAAATGAATTTGTTTTATGG
TTGGAGGAAGCAGATAACATTGCTAGTATCCCACTTGAACCTGGAAAAGAGCAGCAACTAAAAGAAAAGCTTGAGCAAGTCAAGTTACTGGTGGAAGAGT
TGCCCCTGCGCCAGGGAATTCTCAAACAATTAAATGAAACTGGAGGACCCGTGCTTGTAAGTGCTCCCATAAGCCCAGAAGAGCAAGATAAACTTGAAAA
TAAGCTCAAGCAGACAAATCTCCAGTGGATAAAGGTTTCCAGAGCTTTACCTGAGAAACAAGGAGAAATTGAAGCTCAAATAAAAGACCTTGGGCAGCTT
GAAAAAAAGCTTGAAGACCTTGAAGAGCAGTTAAATCATCTGCTGCTGTGGTTATCTCCTATTAGGAATCAGTTGGAAATTTATAACCAACCAAACCAAG
AAGGACCATTTGACGTTAAGGAAACTGAAATAGCAGTTCAAGCTAAACAACCGGATGTGGAAGAGATTTTGTCTAAAGGGCAGCATTTGTACAAGGAAAA
ACCAGCCACTCAGCCAGTGAAGAGGAAGTTAGAAGATCTGAGCTCTGAGTGGAAGGCGGTAAACCGTTTACTTCAAGAGCTGAGGGCAAAGCAGCCTGAC
CTAGCTCCTGGACTGACCACTATTGGAGCCTCTCCTACTCAGACTGTTACTCTGGTGACACAACCTGTGGTTACTAAGGAAACTGCCATCTCCAAACTAG
AAATGCCATCTTCCTTGATGTTGGAGGTACCTGCTCTGGCAGATTTCAACCGGGCTTGGACAGAACTTACCGACTGGCTTTCTCTGCTTGATCAAGTTAT
AAAATCACAGAGGGTGATGGTGGGTGACCTTGAGGATATCAACGAGATGATCATCAAGCAGAAGGCAACAATGCAGGATTTGGAACAGAGGCGTCCCCAG
TTGGAAGAACTCATTACCGCTGCCCAAAATTTGAAAAACAAGACCAGCAATCAAGAGGCTAGAACAATCATTACGGATCGAATTGAAAGAATTCAGAATC
AGTGGGATGAAGTACAAGAACACCTTCAGAACCGGAGGCAACAGTTGAATGAAATGTTAAAGGATTCAACACAATGGCTGGAAGCTAAGGAAGAAGCTGA
GCAGGTCTTAGGACAGGCCAGAGCCAAGCTTGAGTCATGGAAGGAGGGTCCCTATACAGTAGATGCAATCCAAAAGAAAATCACAGAAACCAAGCAGTTG
GCCAAAGACCTCCGCCAGTGGCAGACAAATGTAGATGTGGCAAATGACTTGGCCCTGAAACTTCTCCGGGATTATTCTGCAGATGATACCAGAAAAGTCC
ACATGATAACAGAGAATATCAATGCCTCTTGGAGAAGCATTCATAAAAGGGTGAGTGAGCGAGAGGCTGCTTTGGAAGAAACTCATAGATTACTGCAACA
GTTCCCCCTGGACCTGGAAAAGTTTCTTGCCTGGCTTACAGAAGCTGAAACAACTGCCAATGTCCTACAGGATGCTACCCGTAAGGAAAGGCTCCTAGAA
GACTCCAAGGGAGTAAAAGAGCTGATGAAACAATGGCAAGACCTCCAAGGTGAAATTGAAGCTCACACAGATGTTTATCACAACCTGGATGAAAACAGCC
AAAAAATCCTGAGATCCCTGGAAGGTTCCGATGATGCAGTCCTGTTACAAAGACGTTTGGATAACATGAACTTCAAGTGGAGTGAACTTCGGAAAAAGTC
TCTCAACATTAGGTCCCATTTGGAAGCCAGTTCTGACCAGTGGAAGCGTCTGCACCTTTCTCTGCAGGAACTTCTGGTGTGGCTACAGCTGAAAGATGAT
GAATTAAGCCGGCAGGCACCTATTGGAGGCGACTTTCCAGCAGTTCAGAAGCAGAACGATGTACATAGGGCCTTCAAGAGGGAATTGAAAACTAAAGAAC
CTGTAATCATGAGTACTCTTGAGACTGTACGAATATTTCTGACAGAGCAGCCTTTGGAAGGACTAGAGAAACTCTACCAGGAGCCCAGAGAGCTGCCTCC
TGAGGAGAGAGCCCAGAATGTCACTCGGCTTCTACGAAAGCAGGCTGAGGAGGTCAATACTGAGTGGGAAAAATTGAACCTGCACTCCGCTGACTGGCAG
AGAAAAATAGATGAGACCCTTGAAAGACTCCGGGAACTTCAAGAGGCCACGGATGAGCTGGACCTCAAGCTGCGCCAAGCTGAGGTGATCAAGGGATCCT
GGCAGCCCGTGGGCGATCTCCTCATTGACTCTCTCCAAGATCACCTCGAGAAAGTCAAGGCACTTCGAGGAGAAATTGCGCCTCTGAAAGAGAACGTGAG
CCACGTCAATGACCTTGCTCGCCAGCTTACCACTTTGGGCATTCAGCTCTCACCGTATAACCTCAGCACTCTGGAAGACCTGAACACCAGATGGAAGCTT
CTGCAGGTGGCCGTCGAGGACCGAGTCAGGCAGCTGCATGAAGCCCACAGGGACTTTGGTCCAGCATCTCAGCACTTTCTTTCCACGTCTGTCCAGGGTC
CCTGGGAGAGAGCCATCTCGCCAAACAAAGTGCCCTACTATATCAACCACGAGACTCAAACAACTTGCTGGGACCATCCCAAAATGACAGAGCTCTACCA
GTCTTTAGCTGACCTGAATAATGTCAGATTCTCAGCTTATAGGACTGCCATGAAACTCCGAAGACTGCAGAAGGCCCTTTGCTTGGATCTCTTGAGCCTG
TCAGCTGCATGTGATGCCTTGGACCAGCACAACCTCAAGCAAAATGACCAGCCCATGGATATCCTGCAGATTATTAATTGTTTGACCACTATTTATGACC
GCCTGGAGCAAGAGCACAACAATTTGGTCAACGTCCCTCTCTGCGTGGATATGTGTCTGAACTGGCTGCTGAATGTTTATGATACGGGACGAACAGGGAG
GATCCGTGTCCTGTCTTTTAAAACTGGCATCATTTCCCTGTGTAAAGCACATTTGGAAGACAAGTACAGATACCTTTTCAAGCAAGTGGCAAGTTCAACA
GGATTTTGTGACCAGCGCAGGCTGGGCCTCCTTCTGCATGATTCTATCCAAATTCCAAGACAGTTGGGTGAAGTTGCATCCTTTGGGGGCAGTAACATTG
AGCCAAGTGTCCGGAGCTGCTTCCAATTTGCTAATAATAAGCCAGAGATCGAAGCGGCCCTCTTCCTAGACTGGATGAGACTGGAACCCCAGTCCATGGT
GTGGCTGCCCGTCCTGCACAGAGTGGCTGCTGCAGAAACTGCCAAGCATCAGGCCAAATGTAACATCTGCAAAGAGTGTCCAATCATTGGATTCAGGTAC
AGGAGTCTAAAGCACTTTAATTATGACATCTGCCAAAGCTGCTTTTTTTCTGGTCGAGTTGCAAAAGGCCATAAAATGCACTATCCCATGGTGGAATATT
GCACTCCGACTACATCAGGAGAAGATGTTCGAGACTTTGCCAAGGTACTAAAAAACAAATTTCGAACCAAAAGGTATTTTGCGAAGCATCCCCGAATGGG
CTACCTGCCAGTGCAGACTGTCTTAGAGGGGGACAACATGGAAACTCCCGTTACTCTGATCAACTTCTGGCCAGTAGATTCTGCGCCTGCCTCGTCCCCT
CAGCTTTCACACGATGATACTCATTCACGCATTGAACATTATGCTAGCAGGCTAGCAGAAATGGAAAACAGCAATGGATCTTATCTAAATGATAGCATCT
CTCCTAATGAGAGCATAGATGATGAACATTTGTTAATCCAGCATTACTGCCAAAGTTTGAACCAGGACTCCCCCCTGAGCCAGCCTCGTAGTCCTGCCCA
GATCTTGATTTCCTTAGAGAGTGAGGAAAGAGGGGAGCTAGAGAGAATCCTAGCAGATCTTGAGGAAGAAAACAGGAATCTGCAAGCAGAATATGACCGT
CTAAAGCAGCAGCACGAACATAAAGGCCTGTCCCCACTGCCGTCCCCTCCTGAAATGATGCCCACCTCTCCCCAGAGTCCCCGGGATGCTGAGCTCATTG
CTGAGGCCAAGCTACTGCGTCAACACAAAGGCCGCCTGGAAGCCAGGATGCAAATCCTGGAAGACCACAATAAACAGCTGGAGTCACAGTTACACAGGCT
AAGGCAGCTGCTGGAGCAACCCCAGGCAGAGGCCAAAGTGAATGGCACAACGGTGTCCTCTCCTTCTACCTCTCTACAGAGGTCCGACAGCAGTCAGCCT
ATGCTGCTCCGAGTGGTTGGCAGTCAAACTTCGGACTCCATGGGTGAGGAAGATCTTCTCAGTCCTCCCCAGGACACAAGCACAGGGTTAGAGGAGGTGA
TGGAGCAACTCAACAACTCCTTCCCTAGTTCAAGAGGAAGAAATACCCCTGGAAAGCCAATGAGAGAGGACACAATGTAGGAAGTCTTTTCCACATGGCA
GATGATTTGGGCAGAGCGATGGAGTCCTTAGTATCAGTCATGACAGATGAAGAAGGAGCAGAATAAATGTTTTACAACTCCTGATTCCCGCATGGTTTTT
ATAATATTCATACAACAAAGAGGATTAGACAGTAAGAGTTTACAAGAAATAAATCTATATTTTTGTGAAGGGTAGTGGTATTATACTGTAGATTTCAGTA
GTTTCTAAGTCTGTTATTGTTTTGTTAACAATGGCAGGTTTTACACGTCTATGCAATTGTACAAAAAAGTTATAAGAAAACTACATGTAAAATCTTGATA
GCTAAATAACTTGCCATTTCTTTATATGGAACGCATTTTGGGTTGTTTAAAAATTTATAACAGTTATAAAGAAAGATTGTAAACTAAAGTGTGCTTTATA
AAAAAAAGTTGTTTATAAAAACCCCTAAAAACAAAACAAACACACACACACACACATACACACACACACACAAAACTTTGAGGCAGCGCATTGTTTTGCA
TCCTTTTGGCGTGATATCCATATGAAATTCATGGCTTTTTCTTTTTTTGCATATTAAAGATAAGACTTCCTCTACCACCACACCAAATGACTACTACACA
CTGCTCATTTGAGAACTGTCAGCTGAGTGGGGCAGGCTTGAGTTTTCATTTCATATATCTATATGTCTATAAGTATATAAATACTATAGTTATATAGATA
AAGAGATACGAATTTCTATAGACTGACTTTTTCCATTTTTTAAATGTTCATGTCACATCCTAATAGAAAGAAATTACTTCTAGTCAGTCATCCAGGCTTA
CCTGCTTGGTCTAGAATGGATTTTTCCCGGAGCCGGAAGCCAGGAGGAAACTACACCACACTAAAACATTGTCTACAGCTCCAGATGTTTCTCATTTTAA
ACAACTTTCCACTGACAACGAAAGTAAAGTAAAGTATTGGATTTTTTTAAAGGGAACATGTGAATGAATACACAGGACTTATTATATCAGAGTGAGTAAT
CGGTTGGTTGGTTGATTGATTGATTGATTGATACATTCAGCTTCCTGCTGCTAGCAATGCCACGATTTAGATTTAATGATGCTTCAGTGGAAATCAATCA
GAAGGTATTCTGACCTTGTGAACATCAGAAGGTATTTTTTAACTCCCAAGCAGTAGCAGGACGATGATAGGGCTGGAGGGCTATGGATTCCCAGCCCATC
CCTGTGAAGGAGTAGGCCACTCTTTAAGTGAAGGATTGGATGATTGTTCATAATACATAAAGTTCTCTGTAATTACAACTAAATTATTATGCCCTCTTCT
CACAGTCAAAAGGAACTGGGTGGTTTGGTTTTTGTTGCTTTTTTAGATTTATTGTCCCATGTGGGATGAGTTTTTAAATGCCACAAGACATAATTTAAAA
TAAATAAACTTTGGGAAAAGGTGTAAAACAGTAGCCCCATCACATTTGTGATACTGACAGGTATCAACCCAGAAGCCCATGAACTGTGTTTCCATCCTTT
GCATTTCTCTGCGAGTAGTTCCACACAGGTTTGTAAGTAAGTAAGAAAGAAGGCAAATTGATTCAAATGTTACAAAAAAACCCTTCTTGGTGGATTAGAC
AGGTTAAATATATAAACAAACAAACAAAAATTGCTCAAAAAAGAGGAGAAAAGCTCAAGAGGAAAAGCTAAGGACTGGTAGGAAAAAGCTTTACTCTTTC
ATGCCATTTTATTTCTTTTTGATTTTTAAATCATTCATTCAATAGATACCACCGTGTGACCTATAATTTTGCAAATCTGTTACCTCTGACATCAAGTGTA
ATTAGCTTTTGGAGAGTGGGCTGACATCAAGTGTAATTAGCTTTTGGAGAGTGGGTTTTGTCCATTATTAATAATTAATTAATTAACATCAAACACGGCT
TCTCATGCTATTTCTACCTCACTTTGGTTTTGGGGTGTTCCTGATAATTGTGCACACCTGAGTTCACAGCTTCACCACTTGTCCATTGCGTTATTTTCTT
TTTCCTTTATAATTCTTTCTTTTTCCTTCATAATTTTCAAAAGAAAACCCAAAGCTCTAAGGTAACAAATTACCAAATTACATGAAGATTTGGTTTTTGT
CTTGCATTTTTTTCCTTTATGTGACGCTGGACCTTTTCTTTACCCAAGGATTTTTAAAACTCAGATTTAAAACAAGGGGTTACTTTACATCCTACTAAGA
AGTTTAAGTAAGTAAGTTTCATTCTAAAATCAGAGGTAAATAGAGTGCATAAATAATTTTGTTTTAATCTTTTTGTTTTTCTTTTAGACACATTAGCTCT
GGAGTGAGTCTGTCATAATATTTGAACAAAAATTGAGAGCTTTATTGCTGCATTTTAAGCATAATTAATTTGGACATTATTTCGTGTTGTGTTCTTTATA
ACCACCAAGTATTAAACTGTAAATCATAATGTAACTGAAGCATAAACATCACATGGCATGTTTTGTCATTGTTTTCAGGTACTGAGTTCTTACTTGAGTA
TCATAATATATTGTGTTTTAACACCAACACTGTAACATTTACGAATTATTTTTTTAAACTTCAGTTTTACTGCATTTTCACAACATATCAGACTTCACCA
AATATATGCCTTACTATTGTATTATAGTACTGCTTTACTGTGTATCTCAATAAAGCACGCAGTTATGTTAC
- refseq_DMD.F1 (forward primer)
- refseq_DMD.R1 (reverse primer)
- Alternative donor
Frame 0
**DQEEHST*ERQIAMTEMILLIFFPAYFLNAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQL
AAYIADKVDAAQMPQEAQKIQSDLTSHEISLEE
MKKHNQGKEAAQRVLSQIDVAQKKLQDVSMKFR
LFQKPANFEQRLQESKMILDEVKMHLPALETKSV
EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTG
RQIVQKKQTENPKELDERVTALKLHYNELGAKV
TERKQQLEKCLKLSRKMRKEMNVLTEWLAATDME
LTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKV
HLKSITEVGEALKTVLGKKETLVEDKLSLLNSN
WIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITK
WIIQADTLLDESEKKKPQQKEDVLKRLKAELND
IRPKVDSTRDQAANLMANRGDHCRKLVEPQISE
LNHRFAAISHRIKTGKASIPLKELEQFNSDIQKL
LEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKE
LLQRGDNLQQRITDERKREEIKIKQQLLQTKHN
ALKDLRSQRRKKALEISHQWYQYKRQADDLLKCL
DDIEKKLASLPEPRDERKIKEIDRELQKKKEEL
NAVRRQAEGLSEDGAAMAVEPTQIQLSKRWREI
ESKFAQFRRLNFAQIHTVREETMMVMTEDMPLEI
SYVPSTYLTEITHVSQALLEVEQLLNAPDLCAK
DFEDLFKQEESLKNIKDSLQQSSGRIDIIHSKK
TAALQSATPVERVKLQEALSQLDFQWEKVNKMYK
DRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQF
LRKTQIPENWEHAKYKWYLKELQDGIGQRQTVV
RTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQ
EVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLW
LEEADNIASIPLEPGKEQQLKEKLEQVKLLVEE
LPLRQGILKQLNETGGPVLVSAPISPEEQDKLEN
KLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQL
EKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQ
EGPFDVKETEIAVQAKQPDVEEILSKGQHLYKEK
PATQPVKRKLEDLSSEWKAVNRLLQELRAKQPD
LAPGLTTIGASPTQTVTLVTQPVVTKETAISKL
EMPSSLMLEVPALADFNRAWTELTDWLSLLDQVI
KSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ
LEELITAAQNLKNKTSNQEARTIITDRIERIQN
QWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAE
QVLGQARAKLESWKEGPYTVDAIQKKITETKQL
AKDLRQWQTNVDVANDLALKLLRDYSADDTRKV
HMITENINASWRSIHKRVSEREAALEETHRLLQQ
FPLDLEKFLAWLTEAETTANVLQDATRKERLLE
DSKGVKELMKQWQDLQGEIEAHTDVYHNLDENS
QKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKS
LNIRSHLEASSDQWKRLHLSLQELLVWLQLKDD
ELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKE
PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP
EERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQ
RKIDETLERLRELQEATDELDLKLRQAEVIKGS
WQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVS
HVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKL
LQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQG
PWERAISPNKVPYYINHETQTTCWDHPKMTELYQ
SLADLNNVRFSAYRTAMKLRRLQKALCLDLLSL
SAACDALDQHNLKQNDQPMDILQIINCLTTIYD
RLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGR
IRVLSFKTGIISLCKAHLEDKYRYLFKQVASST
GFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNI
EPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMV
WLPVLHRVAAAETAKHQAKCNICKECPIIGFRY
RSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEY
CTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMG
YLPVQTVLEGDNMETPVTLINFWPVDSAPASSP
QLSHDDTHSRIEHYASRLAEMENSNGSYLNDSI
SPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQ
ILISLESEERGELERILADLEEENRNLQAEYDR
LKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI
AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRL
RQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQP
MLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEV
MEQLNNSFPSSRGRNTPGKPMREDTM*EVFSTWQ
MIWAERWSP*YQS*QMKKEQNKCFTTPDSRMVF
IIFIQQRGLDSKSLQEINLYFCEG*WYYTVDFS
SF*VCYCFVNNGRFYTSMQLYKKVIRKLHVKS**
LNNLPFLYMERILGCLKIYNSYKERL*TKVCFI
KKSCL*KPLKTKQTHTHTHTHTHTKL*GSALFC
ILLA*YPYEIHGFFFFCILKIRLPLPPHQMTTTH
CSFENCQLSGAGLSFHFIYLYVYKYINTIVI*I
KRYEFL*TDFFHFLNVHVTS**KEITSSQSSRL
TCLV*NGFFPEPEARRKLHHTKTLSTAPDVSHFK
QLSTDNESKVKYWIFLKGTCE*IHRTYYIRVSN
RLVG*LID*LIHSASCC*QCHDLDLMMLQWKSI
RRYSDLVNIRRYFLTPKQ*QDDDRAGGLWIPSPS
L*RSRPLFK*RIG*LFIIHKVLCNYN*IIMPSS
HSQKELGGLVFVAFLDLLSHVG*VFKCHKT*FK
INKLWEKV*NSSPITFVILTGINPEAHELCFHPL
HFSASSSTQVCK*VRKKAN*FKCYKKTLLGGLD
RLNI*TNKQKLLKKEEKSSRGKAKDW*EKALLF
HAILFLFDF*IIHSIDTTV*PIILQICYL*HQV*
LAFGEWADIKCN*LLESGFCPLLIIN*LTSNTA
SHAISTSLWFWGVPDNCAHLSSQLHHLSIALFS
FSFIILSFSFIIFKRKPKALR*QITKLHEDLVFV
LHFFPLCDAGPFLYPRIFKTQI*NKGLLYILLR
SLSK*VSF*NQR*IECINNFVLIFLFFF*TH*L
WSESVIIFEQKLRALLLHFKHN*FGHYFVLCSL*
PPSIKL*IIM*LKHKHHMACFVIVFRY*VLT*V
S*YIVF*HQHCNIYELFF*TSVLLHFHNISDFT
KYMPYYCIIVLLYCVSQ*STQLCY
Frame 1
NEIRRNIRPEKDRLQ*LR*FC*FFFQPISLML*GGKSCLNRASSLPRRLKNPYT*SRSPSHSLTSS
WQLILQTRWTQLKCLRKPRKSNLI*QVMRSV*KK
*RNIIRGRRLPKESCLRLMLHRKNYKMSP*SFD
YSRNQPILSSVYKKVR*F*MK*RCTCLHWKQRV
WNRK*YSHS*IIV*TCIKV*VK*SLKWKW**RLD
VRLYRKSRRKIPKNLMKE*QL*NCIIMSWEQR*
QKESNSWRNA*NCPVRCERK*MS*QNGWQLQIW
N*QRDQQLKECLVIWILKLPGERLLKKRLRNRRC
T*RVSQR*ERP*KQFWARRRRWWKINSVF*IVT
G*LSPPEQKSG*IFCWNTRNTWKLLTRMWTTSQ
SGSFRLTHFWMNQRKRNPSKKKTCLSV*RQN*MT
YAQRWTLHVTKQQT*WQTAVTTAGN**SPKSQS
STIDLQPFHTELRLERPPFL*RNWSSLTQIYKN
CLNHWRLKFSRG*I*KRKTSIKI*MKTMRVL*KN
CCKEETTYNKESQMRESERK*R*NSSCYRQNIM
LSRI*GLKEEKRL*KFLISGISTRGRLMIS*NA
WMTLKKN*PAYLSPEMKGK*RKLIGNCRRRKRS*
MQCVGKLRACLRMGPQWQWSQLRSSSASAGGKL
RANLLSFEDSTLHKFTLSVKKR*W**LKTCLWK
FLMCLLLI*LKSLMSHKPY*KWNNFSMLLTSVLR
TLKISLSKRSL*RI*KIVYNKAQVGLTLFIARR
QQHCKVQRLWKG*SYRKLSPSLISNGKKLTKCT
RTDKGDLTDLLRNGGVFIMI*RYLISG*QKLNSF
SERHKFLRIGNMLNTNGILRNSRMALGSGKLLS
EH*MQLGKK*FSNPQKQMPVFYRKNWEA*ICGG
RRSANSCQTEKRG*KNKRISCQNFKEI*MNLFYG
WRKQITLLVSHLNLEKSSN*KKSLSKSSYWWKS
CPCAREFSNN*MKLEDPCL*VLP*AQKSKINLK
ISSSRQISSG*RFPELYLRNKEKLKLK*KTLGSL
KKSLKTLKSS*IICCCGYLLLGISWKFITNQTK
KDHLTLRKLK*QFKLNNRMWKRFCLKGSICTRK
NQPLSQ*RGS*KI*ALSGRR*TVYFKS*GQSSLT
*LLD*PLLEPLLLRLLLW*HNLWLLRKLPSPN*
KCHLP*CWRYLLWQISTGLGQNLPTGFLCLIKL
*NHRG*WWVTLRISTR*SSSRRQQCRIWNRGVPS
WKNSLPLPKI*KTRPAIKRLEQSLRIELKEFRI
SGMKYKNTFRTGGNS*MKC*RIQHNGWKLRKKL
SRS*DRPEPSLSHGRRVPIQ*MQSKRKSQKPSSW
PKTSASGRQM*MWQMTWP*NFSGIILQMIPEKS
T**QRISMPLGEAFIKG*VSERLLWKKLIDYCN
SSPWTWKSFLPGLQKLKQLPMSYRMLPVRKGS*K
TPRE*KS**NNGKTSKVKLKLTQMFITTWMKTA
KKS*DPWKVPMMQSCYKDVWIT*TSSGVNFGKS
LSTLGPIWKPVLTSGSVCTFLCRNFWCGYS*KMM
N*AGRHLLEATFQQFRSRTMYIGPSRGN*KLKN
L*S*VLLRLYEYF*QSSLWKD*RNSTRSPESCL
LRREPRMSLGFYESRLRRSILSGKN*TCTPLTGR
EK*MRPLKDSGNFKRPRMSWTSSCAKLR*SRDP
GSPWAISSLTLSKITSRKSRHFEEKLRL*KRT*
ATSMTLLASLPLWAFSSHRITSALWKT*TPDGSF
CRWPSRTESGSCMKPTGTLVQHLSTFFPRLSRV
PGREPSRQTKCPTISTTRLKQLAGTIPK*QSST
SL*LT*IMSDSQLIGLP*NSEDCRRPFAWIS*AC
QLHVMPWTSTTSSKMTSPWISCRLLIV*PLFMT
AWSKSTTIWSTSLSAWICV*TGC*MFMIRDEQG
GSVSCLLKLASFPCVKHIWKTSTDTFSSKWQVQQ
DFVTSAGWASFCMILSKFQDSWVKLHPLGAVTL
SQVSGAASNLLIISQRSKRPSS*TG*DWNPSPW
CGCPSCTEWLLQKLPSIRPNVTSAKSVQSLDSGT
GV*STLIMTSAKAAFFLVELQKAIKCTIPWWNI
ALRLHQEKMFETLPRY*KTNFEPKGILRSIPEW
ATCQCRLS*RGTTWKLPLL*STSGQ*ILRLPRPL
SFHTMILIHALNIMLAG*QKWKTAMDLI*MIAS
LLMRA*MMNIC*SSITAKV*TRTPP*ASLVVLP
RS*FP*RVRKEGS*RES*QILRKKTGICKQNMTV
*SSSTNIKACPHCRPLLK*CPPLPRVPGMLSSL
LRPSYCVNTKAAWKPGCKSWKTTINSWSHSYTG
*GSCWSNPRQRPK*MAQRCPLLLPLYRGPTAVSL
CCSEWLAVKLRTPWVRKIFSVLPRTQAQG*RR*
WSNSTTPSLVQEEEIPLESQ*ERTQCRKSFPHG
R*FGQSDGVLSISHDR*RRSRINVLQLLIPAWFL
*YSYNKED*TVRVYKK*IYIFVKGSGIIL*ISV
VSKSVIVLLTMAGFTRLCNCTKKL*ENYM*NLD
S*ITCHFFIWNAFWVV*KFITVIKKDCKLKCAL*
KKVVYKNP*KQNKHTHTHIHTHTQNFEAAHCFA
SFWRDIHMKFMAFSFFAY*R*DFLYHHTK*LLH
TAHLRTVS*VGQA*VFISYIYMSISI*IL*LYR*
RDTNFYRLTFSIF*MFMSHPNRKKLLLVSHPGL
PAWSRMDFSRSRKPGGNYTTLKHCLQLQMFLIL
NNFPLTTKVK*SIGFF*REHVNEYTGLIISE*VI
GWLVD*LID*YIQLPAASNATI*I**CFSGNQS
EGILTL*TSEGIF*LPSSSRTMIGLEGYGFPAH
PCEGVGHSLSEGLDDCS*YIKFSVITTKLLCPLL
TVKRNWVVWFLLLF*IYCPMWDEFLNATRHNLK
*INFGKRCKTVAPSHL*Y*QVSTQKPMNCVSIL
CISLRVVPHRFVSK*ERRQIDSNVTKKPFLVD*T
G*IYKQTNKNCSKKRRKAQEEKLRTGRKKLYSF
MPFYFFLIFKSFIQ*IPPCDL*FCKSVTSDIKC
N*LLESGLTSSVISFWRVGFVHY**LIN*HQTRL
LMLFLPHFGFGVFLIIVHT*VHSFTTCPLRYFL
FPL*FFLFPS*FSKENPKL*GNKLPNYMKIWFL
SCIFFLYVTLDLFFTQGFLKLRFKTRGYFTSY*E
V*VSKFHSKIRGK*SA*IILF*SFCFSFRHISS
GVSLS*YLNKN*ELYCCILSIINLDIISCCVLY
NHQVLNCKS*CN*SINITWHVLSLFSGTEFLLEY
HNILCFNTNTVTFTNYFFKLQFYCIFTTYQTSP
NICLTIVL*YCFTVYLNKARSYV
Frame 2
MRSGGTFDLRKTDCND*DDFANFFSSLFP*CCKEAKVA*TEHPVCPGD*KILTLNPGVPHIH*QAV
GSLYCRQGGRSSNASGSPENPI*FDKS*DQFRR
NEET*SGEGGCPKSPVSD*CCTEKITRCLHEVSI
IPETSQF*AASTRK*DDFR*SEDALACIGNKEC
GTGSSTVTAKSLCELV*KSE*SEV*SGNGDKDW
TSDCTEKADGKSQRT**KSNSFEIAL**AGSKGN
RKKATVGEMLEIVP*DAKGNECLDRMAGSYRYG
IDKEISS*RNA**FGF*SCLGKGYSKRD*ETEG
APEEYHRGRRGLENSFGQEGDVGGR*TQSSE**L
DSCHLPSRRVVKSFVGIPETHGNF*PECGPHHK
VDHSG*HTFG*IREKETPAKRRRA*AFKGRTE*
HTPKGGLYT*PSSKLDGKPR*PLQEISRAPNLRA
QPSICSHFTQN*DWKGLHSFEGIGAV*LRYTKI
A*TTGG*NSAGGESERGRLQ*RYE*RQ*GYCKR
IVAKRRQLTTKNHR*EKARGNKDKTAAVTDKT*C
SQGFEVSKKKKGSRNFSSVVSVQEAG**SPEML
G*H*KKISQPT*AQR*KENKGN*SGIAEEERGA
ECSA*AS*GLV*GWGRNGSGANSDPAQQALAGN*
EQICSVSKTQLCTNSHCP*RNDDGDD*RHAFGN
FLCAFYLFD*NHSCLTSPIRSGTTSQCS*PLC*
GL*RSL*ARGVSEEYKR*STTKLRSD*HYS*QED
SSIAKCNACGKGEATGSSLPA*FPMGKS*QNVQ
GPTRAI*QIC*EMAAFSL*YKDI*SVANRS*TV
SQKDTNS*ELGTC*IQMVS*GTPGWHWAAANCCQ
NIECNWGRNNSAILKNRCQYSTGKIGKPESAVA
GGLQTAVRQKKEARRTKEYLVRISKRFK*ICFM
VGGSR*HC*YPT*TWKRAATKRKA*ASQVTGGRV
APAPGNSQTIK*NWRTRACKCSHKPRRAR*T*K
*AQADKSPVDKGFQSFT*ETRRN*SSNKRPWAA
*KKA*RP*RAVKSSAAVVISY*ESVGNL*PTKPR
RTI*R*GN*NSSSS*TTGCGRDFV*RAAFVQGK
TSHSASEEEVRRSEL*VEGGKPFTSRAEGKAA*
PSSWTDHYWSLSYSDCYSGDTTCGY*GNCHLQTR
NAIFLDVGGTCSGRFQPGLDRTYRLAFSA*SSY
KITEGDGG*P*GYQRDDHQAEGNNAGFGTEASP
VGRTHYRCPKFEKQDQQSRG*NNHYGSN*KNSES
VG*STRTPSEPEATVE*NVKGFNTMAGS*GRS*
AGLRTGQSQA*VMEGGSLYSRCNPKENHRNQAV
GQRPPPVADKCRCGK*LGPETSPGLFCR*YQKSP
HDNREYQCLLEKHS*KGE*ARGCFGRNS*ITAT
VPPGPGKVSCLAYRS*NNCQCPTGCYP*GKAPR
RLQGSKRADETMARPPR*N*SSHRCLSQPG*KQP
KNPEIPGRFR*CSPVTKTFG*HELQVE*TSEKV
SQH*VPFGSQF*PVEASAPFSAGTSGVATAER*
*IKPAGTYWRRLSSSSEAERCT*GLQEGIEN*RT
CNHEYS*DCTNISDRAAFGRTRETLPGAQRAAS
*GESPECHSASTKAG*GGQY*VGKIEPALR*LA
EKNR*DP*KTPGTSRGHG*AGPQAAPS*GDQGIL
AARGRSPH*LSPRSPRESQGTSRRNCASERERE
PRQ*PCSPAYHFGHSALTV*PQHSGRPEHQMEA
SAGGRRGPSQAAA*SPQGLWSSISALSFHVCPGS
LGESHLAKQSALLYQPRDSNNLLGPSQNDRALP
VFS*PE*CQILSL*DCHETPKTAEGPLLGSLEP
VSCM*CLGPAQPQAK*PAHGYPADY*LFDHYL*P
PGARAQQFGQRPSLRGYVSELAAECL*YGTNRE
DPCPVF*NWHHFPV*STFGRQVQIPFQASGKFN
RIL*PAQAGPPSA*FYPNSKTVG*SCILWGQ*H*
AKCPELLPIC***ARDRSGPLPRLDETGTPVHG
VAARPAQSGCCRNCQASGQM*HLQRVSNHWIQV
QESKAL*L*HLPKLLFFWSSCKRP*NALSHGGIL
HSDYIRRRCSRLCQGTKKQISNQKVFCEASPNG
LPASADCLRGGQHGNSRYSDQLLASRFCACLVP
SAFTR*YSFTH*TLC*QASRNGKQQWILSK**HL
S**EHR**TFVNPALLPKFEPGLPPEPAS*SCP
DLDFLRE*GKRGARENPSRS*GRKQESASRI*P
SKAAART*RPVPTAVPS*NDAHLSPESPGC*AHC
*GQATASTQRPPGSQDANPGRPQ*TAGVTVTQA
KAAAGATPGRGQSEWHNGVLSFYLSTEVRQQSA
YAAPSGWQSNFGLHG*GRSSQSSPGHKHRVRGGD
GATQQLLP*FKRKKYPWKANERGHNVGSLFHMA
DDLGRAMESLVSVMTDEEGAE*MFYNS*FPHGF
YNIHTTKRIRQ*EFTRNKSIFL*RVVVLYCRFQ*
FLSLLLFC*QWQVLHVYAIVQKSYKKTTCKILI
AK*LAISLYGTHFGLFKNL*QL*RKIVN*SVLY
KKKLFIKTPKNKTNTHTHTYTHTHKTLRQRIVLH
PFGVISI*NSWLFLFLHIKDKTSSTTTPNDYYT
LLI*ELSAEWGRLEFSFHISICL*VYKYYSYID
KEIRISID*LFPFFKCSCHILIERNYF*SVIQAY
LLGLEWIFPGAGSQEETTPH*NIVYSSRCFSF*
TTFH*QRK*SKVLDFFKGNM*MNTQDLLYQSE*
SVGWLID*LIDTFSFLLLAMPRFRFNDASVEINQ
KVF*PCEHQKVFFNSQAVAGR**GWRAMDSQPI
PVKE*ATL*VKDWMIVHNT*SSL*LQLNYYALF
SQSKGTGWFGFCCFFRFIVPCGMSF*MPQDII*N
K*TLGKGVKQ*PHHICDTDRYQPRSP*TVFPSF
AFLCE*FHTGL*VSKKEGKLIQMLQKNPSWWIR
QVKYINKQTKIAQKRGEKLKRKS*GLVGKSFTLS
CHFISF*FLNHSFNRYHRVTYNFANLLPLTSSV
ISFWRVG*HQV*LAFGEWVLSIINN*LINIKHG
FSCYFYLTLVLGCS**LCTPEFTASPLVHCVIFF
FLYNSFFFLHNFQKKTQSSKVTNYQIT*RFGFC
LAFFSFM*RWTFSLPKDF*NSDLKQGVTLHPTK
KFK*VSFILKSEVNRVHK*FCFNLFVFLLDTLAL
E*VCHNI*TKIESFIAAF*A*LIWTLFRVVFFI
TTKY*TVNHNVTEA*TSHGMFCHCFQVLSSYLS
IIIYCVLTPTL*HLRIIFLNFSFTAFSQHIRLHQ
IYALLLYYSTALLCISIKHAVML
Sequence NM_004012
TAATGAGATCAGGAGGAACATTCGACCTGAGAAAGACAGATTGCAATGACTGAGATGATTTTGCTAATTTTTTTTCCAGCCTATTTCCTTAATGTACGTGATATTGTGATTGATTTTCATGCAGAGATCCCTGATCCTATAGTTTTGTTTGCTATTTATTTTTCTCCTTCACATTTTTTTTCTATCAACAGAGCTGAATG
AGTGCCAGGAAGCTGCGAAATCTGTCTTACAAAAAGGCTGTAAGGAGGCAAAAGTTGCTTGAACAGAGCATCCAGTCTGCCCAGGAGACTGAAAAATCCT
TACACTTAATCCAGGAGTCCCTCACATTCATTGACAAGCAGTTGGCAGCTTATATTGCAGACAAGGTGGACGCAGCTCAAATGCCTCAGGAAGCCCAGAA
AATCCAATCTGATTTGACAAGTCATGAGATCAGTTTAGAAGAAATGAAGAAACATAATCAGGGGAAGGAGGCTGCCCAAAGAGTCCTGTCTCAGATTGAT
GTTGCACAGAAAAAATTACAAGATGTCTCCATGAAGTTTCGATTATTCCAGAAACCAGCCAATTTTGAGCAGCGTCTACAAGAAAGTAAGATGATTTTAG
ATGAAGTGAAGATGCACTTGCCTGCATTGGAAACAAAGAGTGTGGAACAGGAAGTAGTACAGTCACAGCTAAATCATTGTGTGAACTTGTATAAAAGTCT
GAGTGAAGTGAAGTCTGAAGTGGAAATGGTGATAAAGACTGGACGTCAGATTGTACAGAAAAAGCAGACGGAAAATCCCAAAGAACTTGATGAAAGAGTA
ACAGCTTTGAAATTGCATTATAATGAGCTGGGAGCAAAGGTAACAGAAAGAAAGCAACAGTTGGAGAAATGCTTGAAATTGTCCCGTAAGATGCGAAAGG
AAATGAATGTCTTGACAGAATGGCTGGCAGCTACAGATATGGAATTGACAAAGAGATCAGCAGTTGAAGGAATGCCTAGTAATTTGGATTCTGAAGTTGC
CTGGGGAAAGGCTACTCAAAAAGAGATTGAGAAACAGAAGGTGCACCTGAAGAGTATCACAGAGGTAGGAGAGGCCTTGAAAACAGTTTTGGGCAAGAAG
GAGACGTTGGTGGAAGATAAACTCAGTCTTCTGAATAGTAACTGGATAGCTGTCACCTCCCGAGCAGAAGAGTGGTTAAATCTTTTGTTGGAATACCAGA
AACACATGGAAACTTTTGACCAGAATGTGGACCACATCACAAAGTGGATCATTCAGGCTGACACACTTTTGGATGAATCAGAGAAAAAGAAACCCCAGCA
AAAAGAAGACGTGCTTAAGCGTTTAAAGGCAGAACTGAATGACATACGCCCAAAGGTGGACTCTACACGTGACCAAGCAGCAAACTTGATGGCAAACCGC
GGTGACCACTGCAGGAAATTAGTAGAGCCCCAAATCTCAGAGCTCAACCATCGATTTGCAGCCATTTCACACAGAATTAAGACTGGAAAGGCCTCCATTC
CTTTGAAGGAATTGGAGCAGTTTAACTCAGATATACAAAAATTGCTTGAACCACTGGAGGCTGAAATTCAGCAGGGGGTGAATCTGAAAGAGGAAGACTT
CAATAAAGATATGAATGAAGACAATGAGGGTACTGTAAAAGAATTGTTGCAAAGAGGAGACAACTTACAACAAAGAATCACAGATGAGAGAAAGCGAGAG
GAAATAAAGATAAAACAGCAGCTGTTACAGACAAAACATAATGCTCTCAAGGATTTGAGGTCTCAAAGAAGAAAAAAGGCTCTAGAAATTTCTCATCAGT
GGTATCAGTACAAGAGGCAGGCTGATGATCTCCTGAAATGCTTGGATGACATTGAAAAAAAATTAGCCAGCCTACCTGAGCCCAGAGATGAAAGGAAAAT
AAAGGAAATTGATCGGGAATTGCAGAAGAAGAAAGAGGAGCTGAATGCAGTGCGTAGGCAAGCTGAGGGCTTGTCTGAGGATGGGGCCGCAATGGCAGTG
GAGCCAACTCAGATCCAGCTCAGCAAGCGCTGGCGGGAAATTGAGAGCAAATTTGCTCAGTTTCGAAGACTCAACTTTGCACAAATTCACACTGTCCGTG
AAGAAACGATGATGGTGATGACTGAAGACATGCCTTTGGAAATTTCTTATGTGCCTTCTACTTATTTGACTGAAATCACTCATGTCTCACAAGCCCTATT
AGAAGTGGAACAACTTCTCAATGCTCCTGACCTCTGTGCTAAGGACTTTGAAGATCTCTTTAAGCAAGAGGAGTCTCTGAAGAATATAAAAGATAGTCTA
CAACAAAGCTCAGGTCGGATTGACATTATTCATAGCAAGAAGACAGCAGCATTGCAAAGTGCAACGCCTGTGGAAAGGGTGAAGCTACAGGAAGCTCTCT
CCCAGCTTGATTTCCAATGGGAAAAAGTTAACAAAATGTACAAGGACCGACAAGGGCGATTTGACAGATCTGTTGAGAAATGGCGGCGTTTTCATTATGA
TATAAAGATATTTAATCAGTGGCTAACAGAAGCTGAACAGTTTCTCAGAAAGACACAAATTCCTGAGAATTGGGAACATGCTAAATACAAATGGTATCTT
AAGGAACTCCAGGATGGCATTGGGCAGCGGCAAACTGTTGTCAGAACATTGAATGCAACTGGGGAAGAAATAATTCAGCAATCCTCAAAAACAGATGCCA
GTATTCTACAGGAAAAATTGGGAAGCCTGAATCTGCGGTGGCAGGAGGTCTGCAAACAGCTGTCAGACAGAAAAAAGAGGCTAGAAGAACAAAAGAATAT
CTTGTCAGAATTTCAAAGAGATTTAAATGAATTTGTTTTATGGTTGGAGGAAGCAGATAACATTGCTAGTATCCCACTTGAACCTGGAAAAGAGCAGCAA
CTAAAAGAAAAGCTTGAGCAAGTCAAGTTACTGGTGGAAGAGTTGCCCCTGCGCCAGGGAATTCTCAAACAATTAAATGAAACTGGAGGACCCGTGCTTG
TAAGTGCTCCCATAAGCCCAGAAGAGCAAGATAAACTTGAAAATAAGCTCAAGCAGACAAATCTCCAGTGGATAAAGGTTTCCAGAGCTTTACCTGAGAA
ACAAGGAGAAATTGAAGCTCAAATAAAAGACCTTGGGCAGCTTGAAAAAAAGCTTGAAGACCTTGAAGAGCAGTTAAATCATCTGCTGCTGTGGTTATCT
CCTATTAGGAATCAGTTGGAAATTTATAACCAACCAAACCAAGAAGGACCATTTGACGTTAAGGAAACTGAAATAGCAGTTCAAGCTAAACAACCGGATG
TGGAAGAGATTTTGTCTAAAGGGCAGCATTTGTACAAGGAAAAACCAGCCACTCAGCCAGTGAAGAGGAAGTTAGAAGATCTGAGCTCTGAGTGGAAGGC
GGTAAACCGTTTACTTCAAGAGCTGAGGGCAAAGCAGCCTGACCTAGCTCCTGGACTGACCACTATTGGAGCCTCTCCTACTCAGACTGTTACTCTGGTG
ACACAACCTGTGGTTACTAAGGAAACTGCCATCTCCAAACTAGAAATGCCATCTTCCTTGATGTTGGAGGTACCTGCTCTGGCAGATTTCAACCGGGCTT
GGACAGAACTTACCGACTGGCTTTCTCTGCTTGATCAAGTTATAAAATCACAGAGGGTGATGGTGGGTGACCTTGAGGATATCAACGAGATGATCATCAA
GCAGAAGGCAACAATGCAGGATTTGGAACAGAGGCGTCCCCAGTTGGAAGAACTCATTACCGCTGCCCAAAATTTGAAAAACAAGACCAGCAATCAAGAG
GCTAGAACAATCATTACGGATCGAATTGAAAGAATTCAGAATCAGTGGGATGAAGTACAAGAACACCTTCAGAACCGGAGGCAACAGTTGAATGAAATGT
TAAAGGATTCAACACAATGGCTGGAAGCTAAGGAAGAAGCTGAGCAGGTCTTAGGACAGGCCAGAGCCAAGCTTGAGTCATGGAAGGAGGGTCCCTATAC
AGTAGATGCAATCCAAAAGAAAATCACAGAAACCAAGCAGTTGGCCAAAGACCTCCGCCAGTGGCAGACAAATGTAGATGTGGCAAATGACTTGGCCCTG
AAACTTCTCCGGGATTATTCTGCAGATGATACCAGAAAAGTCCACATGATAACAGAGAATATCAATGCCTCTTGGAGAAGCATTCATAAAAGGGTGAGTG
AGCGAGAGGCTGCTTTGGAAGAAACTCATAGATTACTGCAACAGTTCCCCCTGGACCTGGAAAAGTTTCTTGCCTGGCTTACAGAAGCTGAAACAACTGC
CAATGTCCTACAGGATGCTACCCGTAAGGAAAGGCTCCTAGAAGACTCCAAGGGAGTAAAAGAGCTGATGAAACAATGGCAAGACCTCCAAGGTGAAATT
GAAGCTCACACAGATGTTTATCACAACCTGGATGAAAACAGCCAAAAAATCCTGAGATCCCTGGAAGGTTCCGATGATGCAGTCCTGTTACAAAGACGTT
TGGATAACATGAACTTCAAGTGGAGTGAACTTCGGAAAAAGTCTCTCAACATTAGGTCCCATTTGGAAGCCAGTTCTGACCAGTGGAAGCGTCTGCACCT
TTCTCTGCAGGAACTTCTGGTGTGGCTACAGCTGAAAGATGATGAATTAAGCCGGCAGGCACCTATTGGAGGCGACTTTCCAGCAGTTCAGAAGCAGAAC
GATGTACATAGGGCCTTCAAGAGGGAATTGAAAACTAAAGAACCTGTAATCATGAGTACTCTTGAGACTGTACGAATATTTCTGACAGAGCAGCCTTTGG
AAGGACTAGAGAAACTCTACCAGGAGCCCAGAGAGCTGCCTCCTGAGGAGAGAGCCCAGAATGTCACTCGGCTTCTACGAAAGCAGGCTGAGGAGGTCAA
TACTGAGTGGGAAAAATTGAACCTGCACTCCGCTGACTGGCAGAGAAAAATAGATGAGACCCTTGAAAGACTCCGGGAACTTCAAGAGGCCACGGATGAG
CTGGACCTCAAGCTGCGCCAAGCTGAGGTGATCAAGGGATCCTGGCAGCCCGTGGGCGATCTCCTCATTGACTCTCTCCAAGATCACCTCGAGAAAGTCA
AGGCACTTCGAGGAGAAATTGCGCCTCTGAAAGAGAACGTGAGCCACGTCAATGACCTTGCTCGCCAGCTTACCACTTTGGGCATTCAGCTCTCACCGTA
TAACCTCAGCACTCTGGAAGACCTGAACACCAGATGGAAGCTTCTGCAGGTGGCCGTCGAGGACCGAGTCAGGCAGCTGCATGAAGCCCACAGGGACTTT
GGTCCAGCATCTCAGCACTTTCTTTCCACGTCTGTCCAGGGTCCCTGGGAGAGAGCCATCTCGCCAAACAAAGTGCCCTACTATATCAACCACGAGACTC
AAACAACTTGCTGGGACCATCCCAAAATGACAGAGCTCTACCAGTCTTTAGCTGACCTGAATAATGTCAGATTCTCAGCTTATAGGACTGCCATGAAACT
CCGAAGACTGCAGAAGGCCCTTTGCTTGGATCTCTTGAGCCTGTCAGCTGCATGTGATGCCTTGGACCAGCACAACCTCAAGCAAAATGACCAGCCCATG
GATATCCTGCAGATTATTAATTGTTTGACCACTATTTATGACCGCCTGGAGCAAGAGCACAACAATTTGGTCAACGTCCCTCTCTGCGTGGATATGTGTC
TGAACTGGCTGCTGAATGTTTATGATACGGGACGAACAGGGAGGATCCGTGTCCTGTCTTTTAAAACTGGCATCATTTCCCTGTGTAAAGCACATTTGGA
AGACAAGTACAGATACCTTTTCAAGCAAGTGGCAAGTTCAACAGGATTTTGTGACCAGCGCAGGCTGGGCCTCCTTCTGCATGATTCTATCCAAATTCCA
AGACAGTTGGGTGAAGTTGCATCCTTTGGGGGCAGTAACATTGAGCCAAGTGTCCGGAGCTGCTTCCAATTTGCTAATAATAAGCCAGAGATCGAAGCGG
CCCTCTTCCTAGACTGGATGAGACTGGAACCCCAGTCCATGGTGTGGCTGCCCGTCCTGCACAGAGTGGCTGCTGCAGAAACTGCCAAGCATCAGGCCAA
ATGTAACATCTGCAAAGAGTGTCCAATCATTGGATTCAGGTACAGGAGTCTAAAGCACTTTAATTATGACATCTGCCAAAGCTGCTTTTTTTCTGGTCGA
GTTGCAAAAGGCCATAAAATGCACTATCCCATGGTGGAATATTGCACTCCGACTACATCAGGAGAAGATGTTCGAGACTTTGCCAAGGTACTAAAAAACA
AATTTCGAACCAAAAGGTATTTTGCGAAGCATCCCCGAATGGGCTACCTGCCAGTGCAGACTGTCTTAGAGGGGGACAACATGGAAACTCCCGTTACTCT
GATCAACTTCTGGCCAGTAGATTCTGCGCCTGCCTCGTCCCCTCAGCTTTCACACGATGATACTCATTCACGCATTGAACATTATGCTAGCAGGCTAGCA
GAAATGGAAAACAGCAATGGATCTTATCTAAATGATAGCATCTCTCCTAATGAGAGCATAGATGATGAACATTTGTTAATCCAGCATTACTGCCAAAGTT
TGAACCAGGACTCCCCCCTGAGCCAGCCTCGTAGTCCTGCCCAGATCTTGATTTCCTTAGAGAGTGAGGAAAGAGGGGAGCTAGAGAGAATCCTAGCAGA
TCTTGAGGAAGAAAACAGGAATCTGCAAGCAGAATATGACCGTCTAAAGCAGCAGCACGAACATAAAGGCCTGTCCCCACTGCCGTCCCCTCCTGAAATG
ATGCCCACCTCTCCCCAGAGTCCCCGGGATGCTGAGCTCATTGCTGAGGCCAAGCTACTGCGTCAACACAAAGGCCGCCTGGAAGCCAGGATGCAAATCC
TGGAAGACCACAATAAACAGCTGGAGTCACAGTTACACAGGCTAAGGCAGCTGCTGGAGCAACCCCAGGCAGAGGCCAAAGTGAATGGCACAACGGTGTC
CTCTCCTTCTACCTCTCTACAGAGGTCCGACAGCAGTCAGCCTATGCTGCTCCGAGTGGTTGGCAGTCAAACTTCGGACTCCATGGGTGAGGAAGATCTT
CTCAGTCCTCCCCAGGACACAAGCACAGGGTTAGAGGAGGTGATGGAGCAACTCAACAACTCCTTCCCTAGTTCAAGAGGAAGAAATACCCCTGGAAAGC
CAATGAGAGAGGACACAATGTAGGAAGTCTTTTCCACATGGCAGATGATTTGGGCAGAGCGATGGAGTCCTTAGTATCAGTCATGACAGATGAAGAAGGA
GCAGAATAAATGTTTTACAACTCCTGATTCCCGCATGGTTTTTATAATATTCATACAACAAAGAGGATTAGACAGTAAGAGTTTACAAGAAATAAATCTA
TATTTTTGTGAAGGGTAGTGGTATTATACTGTAGATTTCAGTAGTTTCTAAGTCTGTTATTGTTTTGTTAACAATGGCAGGTTTTACACGTCTATGCAAT
TGTACAAAAAAGTTATAAGAAAACTACATGTAAAATCTTGATAGCTAAATAACTTGCCATTTCTTTATATGGAACGCATTTTGGGTTGTTTAAAAATTTA
TAACAGTTATAAAGAAAGATTGTAAACTAAAGTGTGCTTTATAAAAAAAAGTTGTTTATAAAAACCCCTAAAAACAAAACAAACACACACACACACACAT
ACACACACACACACAAAACTTTGAGGCAGCGCATTGTTTTGCATCCTTTTGGCGTGATATCCATATGAAATTCATGGCTTTTTCTTTTTTTGCATATTAA
AGATAAGACTTCCTCTACCACCACACCAAATGACTACTACACACTGCTCATTTGAGAACTGTCAGCTGAGTGGGGCAGGCTTGAGTTTTCATTTCATATA
TCTATATGTCTATAAGTATATAAATACTATAGTTATATAGATAAAGAGATACGAATTTCTATAGACTGACTTTTTCCATTTTTTAAATGTTCATGTCACA
TCCTAATAGAAAGAAATTACTTCTAGTCAGTCATCCAGGCTTACCTGCTTGGTCTAGAATGGATTTTTCCCGGAGCCGGAAGCCAGGAGGAAACTACACC
ACACTAAAACATTGTCTACAGCTCCAGATGTTTCTCATTTTAAACAACTTTCCACTGACAACGAAAGTAAAGTAAAGTATTGGATTTTTTTAAAGGGAAC
ATGTGAATGAATACACAGGACTTATTATATCAGAGTGAGTAATCGGTTGGTTGGTTGATTGATTGATTGATTGATACATTCAGCTTCCTGCTGCTAGCAA
TGCCACGATTTAGATTTAATGATGCTTCAGTGGAAATCAATCAGAAGGTATTCTGACCTTGTGAACATCAGAAGGTATTTTTTAACTCCCAAGCAGTAGC
AGGACGATGATAGGGCTGGAGGGCTATGGATTCCCAGCCCATCCCTGTGAAGGAGTAGGCCACTCTTTAAGTGAAGGATTGGATGATTGTTCATAATACA
TAAAGTTCTCTGTAATTACAACTAAATTATTATGCCCTCTTCTCACAGTCAAAAGGAACTGGGTGGTTTGGTTTTTGTTGCTTTTTTAGATTTATTGTCC
CATGTGGGATGAGTTTTTAAATGCCACAAGACATAATTTAAAATAAATAAACTTTGGGAAAAGGTGTAAAACAGTAGCCCCATCACATTTGTGATACTGA
CAGGTATCAACCCAGAAGCCCATGAACTGTGTTTCCATCCTTTGCATTTCTCTGCGAGTAGTTCCACACAGGTTTGTAAGTAAGTAAGAAAGAAGGCAAA
TTGATTCAAATGTTACAAAAAAACCCTTCTTGGTGGATTAGACAGGTTAAATATATAAACAAACAAACAAAAATTGCTCAAAAAAGAGGAGAAAAGCTCA
AGAGGAAAAGCTAAGGACTGGTAGGAAAAAGCTTTACTCTTTCATGCCATTTTATTTCTTTTTGATTTTTAAATCATTCATTCAATAGATACCACCGTGT
GACCTATAATTTTGCAAATCTGTTACCTCTGACATCAAGTGTAATTAGCTTTTGGAGAGTGGGCTGACATCAAGTGTAATTAGCTTTTGGAGAGTGGGTT
TTGTCCATTATTAATAATTAATTAATTAACATCAAACACGGCTTCTCATGCTATTTCTACCTCACTTTGGTTTTGGGGTGTTCCTGATAATTGTGCACAC
CTGAGTTCACAGCTTCACCACTTGTCCATTGCGTTATTTTCTTTTTCCTTTATAATTCTTTCTTTTTCCTTCATAATTTTCAAAAGAAAACCCAAAGCTC
TAAGGTAACAAATTACCAAATTACATGAAGATTTGGTTTTTGTCTTGCATTTTTTTCCTTTATGTGACGCTGGACCTTTTCTTTACCCAAGGATTTTTAA
AACTCAGATTTAAAACAAGGGGTTACTTTACATCCTACTAAGAAGTTTAAGTAAGTAAGTTTCATTCTAAAATCAGAGGTAAATAGAGTGCATAAATAAT
TTTGTTTTAATCTTTTTGTTTTTCTTTTAGACACATTAGCTCTGGAGTGAGTCTGTCATAATATTTGAACAAAAATTGAGAGCTTTATTGCTGCATTTTA
AGCATAATTAATTTGGACATTATTTCGTGTTGTGTTCTTTATAACCACCAAGTATTAAACTGTAAATCATAATGTAACTGAAGCATAAACATCACATGGC
ATGTTTTGTCATTGTTTTCAGGTACTGAGTTCTTACTTGAGTATCATAATATATTGTGTTTTAACACCAACACTGTAACATTTACGAATTATTTTTTTAA
ACTTCAGTTTTACTGCATTTTCACAACATATCAGACTTCACCAAATATATGCCTTACTATTGTATTATAGTACTGCTTTACTGTGTATCTCAATAAAGCA
CGCAGTTATGTTAC
- refseq_DMD.F1 (forward primer)
- refseq_DMD.R1 (reverse primer)
- Alternative donor
Frame 0
**DQEEHST*ERQIAMTEMILLIFFPAYFLNVRDIVIDFHAEIPDPIVLFAIYFSPSHFFSINRAE*
VPGSCEICLTKRL*GGKSCLNRASSLPRRLKNP
YT*SRSPSHSLTSSWQLILQTRWTQLKCLRKPR
KSNLI*QVMRSV*KK*RNIIRGRRLPKESCLRLM
LHRKNYKMSP*SFDYSRNQPILSSVYKKVR*F*
MK*RCTCLHWKQRVWNRK*YSHS*IIV*TCIKV
*VK*SLKWKW**RLDVRLYRKSRRKIPKNLMKE*
QL*NCIIMSWEQR*QKESNSWRNA*NCPVRCER
K*MS*QNGWQLQIWN*QRDQQLKECLVIWILKL
PGERLLKKRLRNRRCT*RVSQR*ERP*KQFWARR
RRWWKINSVF*IVTG*LSPPEQKSG*IFCWNTR
NTWKLLTRMWTTSQSGSFRLTHFWMNQRKRNPS
KKKTCLSV*RQN*MTYAQRWTLHVTKQQT*WQTA
VTTAGN**SPKSQSSTIDLQPFHTELRLERPPF
L*RNWSSLTQIYKNCLNHWRLKFSRG*I*KRKT
SIKI*MKTMRVL*KNCCKEETTYNKESQMRESER
K*R*NSSCYRQNIMLSRI*GLKEEKRL*KFLIS
GISTRGRLMIS*NAWMTLKKN*PAYLSPEMKGK
*RKLIGNCRRRKRS*MQCVGKLRACLRMGPQWQW
SQLRSSSASAGGKLRANLLSFEDSTLHKFTLSV
KKR*W**LKTCLWKFLMCLLLI*LKSLMSHKPY
*KWNNFSMLLTSVLRTLKISLSKRSL*RI*KIVY
NKAQVGLTLFIARRQQHCKVQRLWKG*SYRKLS
PSLISNGKKLTKCTRTDKGDLTDLLRNGGVFIM
I*RYLISG*QKLNSFSERHKFLRIGNMLNTNGIL
RNSRMALGSGKLLSEH*MQLGKK*FSNPQKQMP
VFYRKNWEA*ICGGRRSANSCQTEKRG*KNKRI
SCQNFKEI*MNLFYGWRKQITLLVSHLNLEKSSN
*KKSLSKSSYWWKSCPCAREFSNN*MKLEDPCL
*VLP*AQKSKINLKISSSRQISSG*RFPELYLR
NKEKLKLK*KTLGSLKKSLKTLKSS*IICCCGYL
LLGISWKFITNQTKKDHLTLRKLK*QFKLNNRM
WKRFCLKGSICTRKNQPLSQ*RGS*KI*ALSGR
R*TVYFKS*GQSSLT*LLD*PLLEPLLLRLLLW*
HNLWLLRKLPSPN*KCHLP*CWRYLLWQISTGL
GQNLPTGFLCLIKL*NHRG*WWVTLRISTR*SS
SRRQQCRIWNRGVPSWKNSLPLPKI*KTRPAIKR
LEQSLRIELKEFRISGMKYKNTFRTGGNS*MKC
*RIQHNGWKLRKKLSRS*DRPEPSLSHGRRVPI
Q*MQSKRKSQKPSSWPKTSASGRQM*MWQMTWP*
NFSGIILQMIPEKST**QRISMPLGEAFIKG*V
SERLLWKKLIDYCNSSPWTWKSFLPGLQKLKQL
PMSYRMLPVRKGS*KTPRE*KS**NNGKTSKVKL
KLTQMFITTWMKTAKKS*DPWKVPMMQSCYKDV
WIT*TSSGVNFGKSLSTLGPIWKPVLTSGSVCT
FLCRNFWCGYS*KMMN*AGRHLLEATFQQFRSRT
MYIGPSRGN*KLKNL*S*VLLRLYEYF*QSSLW
KD*RNSTRSPESCLLRREPRMSLGFYESRLRRS
ILSGKN*TCTPLTGREK*MRPLKDSGNFKRPRMS
WTSSCAKLR*SRDPGSPWAISSLTLSKITSRKS
RHFEEKLRL*KRT*ATSMTLLASLPLWAFSSHR
ITSALWKT*TPDGSFCRWPSRTESGSCMKPTGTL
VQHLSTFFPRLSRVPGREPSRQTKCPTISTTRL
KQLAGTIPK*QSSTSL*LT*IMSDSQLIGLP*N
SEDCRRPFAWIS*ACQLHVMPWTSTTSSKMTSPW
ISCRLLIV*PLFMTAWSKSTTIWSTSLSAWICV
*TGC*MFMIRDEQGGSVSCLLKLASFPCVKHIW
KTSTDTFSSKWQVQQDFVTSAGWASFCMILSKFQ
DSWVKLHPLGAVTLSQVSGAASNLLIISQRSKR
PSS*TG*DWNPSPWCGCPSCTEWLLQKLPSIRP
NVTSAKSVQSLDSGTGV*STLIMTSAKAAFFLVE
LQKAIKCTIPWWNIALRLHQEKMFETLPRY*KT
NFEPKGILRSIPEWATCQCRLS*RGTTWKLPLL
*STSGQ*ILRLPRPLSFHTMILIHALNIMLAG*Q
KWKTAMDLI*MIASLLMRA*MMNIC*SSITAKV
*TRTPP*ASLVVLPRS*FP*RVRKEGS*RES*Q
ILRKKTGICKQNMTV*SSSTNIKACPHCRPLLK*
CPPLPRVPGMLSSLLRPSYCVNTKAAWKPGCKS
WKTTINSWSHSYTG*GSCWSNPRQRPK*MAQRC
PLLLPLYRGPTAVSLCCSEWLAVKLRTPWVRKIF
SVLPRTQAQG*RR*WSNSTTPSLVQEEEIPLES
Q*ERTQCRKSFPHGR*FGQSDGVLSISHDR*RR
SRINVLQLLIPAWFL*YSYNKED*TVRVYKK*IY
IFVKGSGIIL*ISVVSKSVIVLLTMAGFTRLCN
CTKKL*ENYM*NLDS*ITCHFFIWNAFWVV*KF
ITVIKKDCKLKCAL*KKVVYKNP*KQNKHTHTHI
HTHTQNFEAAHCFASFWRDIHMKFMAFSFFAY*
R*DFLYHHTK*LLHTAHLRTVS*VGQA*VFISY
IYMSISI*IL*LYR*RDTNFYRLTFSIF*MFMSH
PNRKKLLLVSHPGLPAWSRMDFSRSRKPGGNYT
TLKHCLQLQMFLILNNFPLTTKVK*SIGFF*RE
HVNEYTGLIISE*VIGWLVD*LID*YIQLPAASN
ATI*I**CFSGNQSEGILTL*TSEGIF*LPSSS
RTMIGLEGYGFPAHPCEGVGHSLSEGLDDCS*Y
IKFSVITTKLLCPLLTVKRNWVVWFLLLF*IYCP
MWDEFLNATRHNLK*INFGKRCKTVAPSHL*Y*
QVSTQKPMNCVSILCISLRVVPHRFVSK*ERRQ
IDSNVTKKPFLVD*TG*IYKQTNKNCSKKRRKAQ
EEKLRTGRKKLYSFMPFYFFLIFKSFIQ*IPPC
DL*FCKSVTSDIKCN*LLESGLTSSVISFWRVG
FVHY**LIN*HQTRLLMLFLPHFGFGVFLIIVHT
*VHSFTTCPLRYFLFPL*FFLFPS*FSKENPKL
*GNKLPNYMKIWFLSCIFFLYVTLDLFFTQGFL
KLRFKTRGYFTSY*EV*VSKFHSKIRGK*SA*II
LF*SFCFSFRHISSGVSLS*YLNKN*ELYCCIL
SIINLDIISCCVLYNHQVLNCKS*CN*SINITW
HVLSLFSGTEFLLEYHNILCFNTNTVTFTNYFFK
LQFYCIFTTYQTSPNICLTIVL*YCFTVYLNKA
RSYV
Frame 1
NEIRRNIRPEKDRLQ*LR*FC*FFFQPISLMYVIL*LIFMQRSLIL*FCLLFIFLLHIFFLSTELN
ECQEAAKSVLQKGCKEAKVA*TEHPVCPGD*KIL
TLNPGVPHIH*QAVGSLYCRQGGRSSNASGSPE
NPI*FDKS*DQFRRNEET*SGEGGCPKSPVSD*
CCTEKITRCLHEVSIIPETSQF*AASTRK*DDFR
*SEDALACIGNKECGTGSSTVTAKSLCELV*KS
E*SEV*SGNGDKDWTSDCTEKADGKSQRT**KS
NSFEIAL**AGSKGNRKKATVGEMLEIVP*DAKG
NECLDRMAGSYRYGIDKEISS*RNA**FGF*SC
LGKGYSKRD*ETEGAPEEYHRGRRGLENSFGQE
GDVGGR*TQSSE**LDSCHLPSRRVVKSFVGIPE
THGNF*PECGPHHKVDHSG*HTFG*IREKETPA
KRRRA*AFKGRTE*HTPKGGLYT*PSSKLDGKP
R*PLQEISRAPNLRAQPSICSHFTQN*DWKGLHS
FEGIGAV*LRYTKIA*TTGG*NSAGGESERGRL
Q*RYE*RQ*GYCKRIVAKRRQLTTKNHR*EKAR
GNKDKTAAVTDKT*CSQGFEVSKKKKGSRNFSSV
VSVQEAG**SPEMLG*H*KKISQPT*AQR*KEN
KGN*SGIAEEERGAECSA*AS*GLV*GWGRNGS
GANSDPAQQALAGN*EQICSVSKTQLCTNSHCP*
RNDDGDD*RHAFGNFLCAFYLFD*NHSCLTSPI
RSGTTSQCS*PLC*GL*RSL*ARGVSEEYKR*S
TTKLRSD*HYS*QEDSSIAKCNACGKGEATGSSL
PA*FPMGKS*QNVQGPTRAI*QIC*EMAAFSL*
YKDI*SVANRS*TVSQKDTNS*ELGTC*IQMVS
*GTPGWHWAAANCCQNIECNWGRNNSAILKNRCQ
YSTGKIGKPESAVAGGLQTAVRQKKEARRTKEY
LVRISKRFK*ICFMVGGSR*HC*YPT*TWKRAA
TKRKA*ASQVTGGRVAPAPGNSQTIK*NWRTRAC
KCSHKPRRAR*T*K*AQADKSPVDKGFQSFT*E
TRRN*SSNKRPWAA*KKA*RP*RAVKSSAAVVI
SY*ESVGNL*PTKPRRTI*R*GN*NSSSS*TTGC
GRDFV*RAAFVQGKTSHSASEEEVRRSEL*VEG
GKPFTSRAEGKAA*PSSWTDHYWSLSYSDCYSG
DTTCGY*GNCHLQTRNAIFLDVGGTCSGRFQPGL
DRTYRLAFSA*SSYKITEGDGG*P*GYQRDDHQ
AEGNNAGFGTEASPVGRTHYRCPKFEKQDQQSR
G*NNHYGSN*KNSESVG*STRTPSEPEATVE*NV
KGFNTMAGS*GRS*AGLRTGQSQA*VMEGGSLY
SRCNPKENHRNQAVGQRPPPVADKCRCGK*LGP
ETSPGLFCR*YQKSPHDNREYQCLLEKHS*KGE*
ARGCFGRNS*ITATVPPGPGKVSCLAYRS*NNC
QCPTGCYP*GKAPRRLQGSKRADETMARPPR*N
*SSHRCLSQPG*KQPKNPEIPGRFR*CSPVTKTF
G*HELQVE*TSEKVSQH*VPFGSQF*PVEASAP
FSAGTSGVATAER**IKPAGTYWRRLSSSSEAE
RCT*GLQEGIEN*RTCNHEYS*DCTNISDRAAFG
RTRETLPGAQRAAS*GESPECHSASTKAG*GGQ
Y*VGKIEPALR*LAEKNR*DP*KTPGTSRGHG*
AGPQAAPS*GDQGILAARGRSPH*LSPRSPRESQ
GTSRRNCASEREREPRQ*PCSPAYHFGHSALTV
*PQHSGRPEHQMEASAGGRRGPSQAAA*SPQGL
WSSISALSFHVCPGSLGESHLAKQSALLYQPRDS
NNLLGPSQNDRALPVFS*PE*CQILSL*DCHET
PKTAEGPLLGSLEPVSCM*CLGPAQPQAK*PAH
GYPADY*LFDHYL*PPGARAQQFGQRPSLRGYVS
ELAAECL*YGTNREDPCPVF*NWHHFPV*STFG
RQVQIPFQASGKFNRIL*PAQAGPPSA*FYPNS
KTVG*SCILWGQ*H*AKCPELLPIC***ARDRSG
PLPRLDETGTPVHGVAARPAQSGCCRNCQASGQ
M*HLQRVSNHWIQVQESKAL*L*HLPKLLFFWS
SCKRP*NALSHGGILHSDYIRRRCSRLCQGTKKQ
ISNQKVFCEASPNGLPASADCLRGGQHGNSRYS
DQLLASRFCACLVPSAFTR*YSFTH*TLC*QAS
RNGKQQWILSK**HLS**EHR**TFVNPALLPKF
EPGLPPEPAS*SCPDLDFLRE*GKRGARENPSR
S*GRKQESASRI*PSKAAART*RPVPTAVPS*N
DAHLSPESPGC*AHC*GQATASTQRPPGSQDANP
GRPQ*TAGVTVTQAKAAAGATPGRGQSEWHNGV
LSFYLSTEVRQQSAYAAPSGWQSNFGLHG*GRS
SQSSPGHKHRVRGGDGATQQLLP*FKRKKYPWKA
NERGHNVGSLFHMADDLGRAMESLVSVMTDEEG
AE*MFYNS*FPHGFYNIHTTKRIRQ*EFTRNKS
IFL*RVVVLYCRFQ*FLSLLLFC*QWQVLHVYAI
VQKSYKKTTCKILIAK*LAISLYGTHFGLFKNL
*QL*RKIVN*SVLYKKKLFIKTPKNKTNTHTHT
YTHTHKTLRQRIVLHPFGVISI*NSWLFLFLHIK
DKTSSTTTPNDYYTLLI*ELSAEWGRLEFSFHI
SICL*VYKYYSYIDKEIRISID*LFPFFKCSCH
ILIERNYF*SVIQAYLLGLEWIFPGAGSQEETTP
H*NIVYSSRCFSF*TTFH*QRK*SKVLDFFKGN
M*MNTQDLLYQSE*SVGWLID*LIDTFSFLLLA
MPRFRFNDASVEINQKVF*PCEHQKVFFNSQAVA
GR**GWRAMDSQPIPVKE*ATL*VKDWMIVHNT
*SSL*LQLNYYALFSQSKGTGWFGFCCFFRFIV
PCGMSF*MPQDII*NK*TLGKGVKQ*PHHICDTD
RYQPRSP*TVFPSFAFLCE*FHTGL*VSKKEGK
LIQMLQKNPSWWIRQVKYINKQTKIAQKRGEKL
KRKS*GLVGKSFTLSCHFISF*FLNHSFNRYHRV
TYNFANLLPLTSSVISFWRVG*HQV*LAFGEWV
LSIINN*LINIKHGFSCYFYLTLVLGCS**LCT
PEFTASPLVHCVIFFFLYNSFFFLHNFQKKTQSS
KVTNYQIT*RFGFCLAFFSFM*RWTFSLPKDF*
NSDLKQGVTLHPTKKFK*VSFILKSEVNRVHK*
FCFNLFVFLLDTLALE*VCHNI*TKIESFIAAF*
A*LIWTLFRVVFFITTKY*TVNHNVTEA*TSHG
MFCHCFQVLSSYLSIIIYCVLTPTL*HLRIIFL
NFSFTAFSQHIRLHQIYALLLYYSTALLCISIKH
AVML
Frame 2
MRSGGTFDLRKTDCND*DDFANFFSSLFP*CT*YCD*FSCRDP*SYSFVCYLFFSFTFFFYQQS*M
SARKLRNLSYKKAVRRQKLLEQSIQSAQETEKS
LHLIQESLTFIDKQLAAYIADKVDAAQMPQEAQK
IQSDLTSHEISLEEMKKHNQGKEAAQRVLSQID
VAQKKLQDVSMKFRLFQKPANFEQRLQESKMIL
DEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSL
SEVKSEVEMVIKTGRQIVQKKQTENPKELDERV
TALKLHYNELGAKVTERKQQLEKCLKLSRKMRK
EMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVA
WGKATQKEIEKQKVHLKSITEVGEALKTVLGKK
ETLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQ
KHMETFDQNVDHITKWIIQADTLLDESEKKKPQQ
KEDVLKRLKAELNDIRPKVDSTRDQAANLMANR
GDHCRKLVEPQISELNHRFAAISHRIKTGKASI
PLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDF
NKDMNEDNEGTVKELLQRGDNLQQRITDERKRE
EIKIKQQLLQTKHNALKDLRSQRRKKALEISHQ
WYQYKRQADDLLKCLDDIEKKLASLPEPRDERKI
KEIDRELQKKKEELNAVRRQAEGLSEDGAAMAV
EPTQIQLSKRWREIESKFAQFRRLNFAQIHTVR
EETMMVMTEDMPLEISYVPSTYLTEITHVSQALL
EVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSL
QQSSGRIDIIHSKKTAALQSATPVERVKLQEAL
SQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYD
IKIFNQWLTEAEQFLRKTQIPENWEHAKYKWYL
KELQDGIGQRQTVVRTLNATGEEIIQQSSKTDA
SILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNI
LSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQ
LKEKLEQVKLLVEELPLRQGILKQLNETGGPVL
VSAPISPEEQDKLENKLKQTNLQWIKVSRALPEK
QGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLS
PIRNQLEIYNQPNQEGPFDVKETEIAVQAKQPD
VEEILSKGQHLYKEKPATQPVKRKLEDLSSEWKA
VNRLLQELRAKQPDLAPGLTTIGASPTQTVTLV
TQPVVTKETAISKLEMPSSLMLEVPALADFNRA
WTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIK
QKATMQDLEQRRPQLEELITAAQNLKNKTSNQE
ARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM
LKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYT
VDAIQKKITETKQLAKDLRQWQTNVDVANDLAL
KLLRDYSADDTRKVHMITENINASWRSIHKRVS
EREAALEETHRLLQQFPLDLEKFLAWLTEAETTA
NVLQDATRKERLLEDSKGVKELMKQWQDLQGEI
EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRR
LDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHL
SLQELLVWLQLKDDELSRQAPIGGDFPAVQKQN
DVHRAFKRELKTKEPVIMSTLETVRIFLTEQPL
EGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVN
TEWEKLNLHSADWQRKIDETLERLRELQEATDE
LDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV
KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPY
NLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDF
GPASQHFLSTSVQGPWERAISPNKVPYYINHET
QTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKL
RRLQKALCLDLLSLSAACDALDQHNLKQNDQPM
DILQIINCLTTIYDRLEQEHNNLVNVPLCVDMC
LNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE
DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIP
RQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA
ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAK
CNICKECPIIGFRYRSLKHFNYDICQSCFFSGR
VAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKN
KFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTL
INFWPVDSAPASSPQLSHDDTHSRIEHYASRLA
EMENSNGSYLNDSISPNESIDDEHLLIQHYCQS
LNQDSPLSQPRSPAQILISLESEERGELERILAD
LEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEM
MPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI
LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVS
SPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDL
LSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGK
PMREDTM*EVFSTWQMIWAERWSP*YQS*QMKKE
QNKCFTTPDSRMVFIIFIQQRGLDSKSLQEINL
YFCEG*WYYTVDFSSF*VCYCFVNNGRFYTSMQ
LYKKVIRKLHVKS**LNNLPFLYMERILGCLKIY
NSYKERL*TKVCFIKKSCL*KPLKTKQTHTHTH
THTHTKL*GSALFCILLA*YPYEIHGFFFFCIL
KIRLPLPPHQMTTTHCSFENCQLSGAGLSFHFIY
LYVYKYINTIVI*IKRYEFL*TDFFHFLNVHVT
S**KEITSSQSSRLTCLV*NGFFPEPEARRKLH
HTKTLSTAPDVSHFKQLSTDNESKVKYWIFLKGT
CE*IHRTYYIRVSNRLVG*LID*LIHSASCC*Q
CHDLDLMMLQWKSIRRYSDLVNIRRYFLTPKQ*
QDDDRAGGLWIPSPSL*RSRPLFK*RIG*LFIIH
KVLCNYN*IIMPSSHSQKELGGLVFVAFLDLLS
HVG*VFKCHKT*FKINKLWEKV*NSSPITFVIL
TGINPEAHELCFHPLHFSASSSTQVCK*VRKKAN
*FKCYKKTLLGGLDRLNI*TNKQKLLKKEEKSS
RGKAKDW*EKALLFHAILFLFDF*IIHSIDTTV
*PIILQICYL*HQV*LAFGEWADIKCN*LLESGF
CPLLIIN*LTSNTASHAISTSLWFWGVPDNCAH
LSSQLHHLSIALFSFSFIILSFSFIIFKRKPKA
LR*QITKLHEDLVFVLHFFPLCDAGPFLYPRIFK
TQI*NKGLLYILLRSLSK*VSF*NQR*IECINN
FVLIFLFFF*TH*LWSESVIIFEQKLRALLLHF
KHN*FGHYFVLCSL*PPSIKL*IIM*LKHKHHMA
CFVIVFRY*VLT*VS*YIVF*HQHCNIYELFF*
TSVLLHFHNISDFTKYMPYYCIIVLLYCVSQ*S
TQLCY
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