Back to Rnomics Platform
 Open Session
×
1 warning:
  • Access restricted to public data.
    Please sign in at Rnomics Platform to access your data.
Navigation
Home
Sequences

Sequence NM_001013005

AGCACTTGAAGTTCAGGCAGCGAGAGTTGACATGGGGCCAGGGCTGCGCCCCTGGGGCGGGTTGAAGACAGGGTGAGTCTCTTGATATTCAGGAAATCAT
CGCGCACCCAGTCACCAGCGTTCGGGAGCCTGTCGCAGCGGGACCGACGGAATCCGGAGCAGGCGACAGGGCGCAGAAGCGGGATGTACTTCTGTTGGGG
CGCCGACTCCAGGGAGCTGCAGCGCCGGAGGACGGCGGGCAGCCCCGGGGCTGAGCTACTGCAGGCGGCCAGCGGGGAGCGCCACTCTCTGCTGCTGCTG
ACCAACCACAGGGTCCTCTCGTGCGGAGACAACAGCAGGGGTCAGCTGGGCCGCAGGGCGCGCAGCGCGGGGAGCTGCCAGAACCAATTCAGGCATTGGA
AACCCTAATTGTTGATCTCGTGAGCTGCGGGAAGGAGCACTCCCTGGCTGTGTGCCACAAAGGAAGGGTCTTCGCATGGGGAGCTGGTTCTGAAGGGCAG
CTGGGGATTGGAGAATTCAAGGAAATAAGTTTCACACCTAAGAAAATAATGACTCTGAATGATATAAAAATAATACAAGTTTCCTGTGGACACTACCACT
CCCTGGCATTATCAAAAGATAGCCAAGTGTTTTCGTGGGGAAAGAACAGCCATGGGCAGCTGGGCTTGGGGAAGGAGTTCCCCTCCCAAGCCAGCCCGCA
GAGGGTGAGGTCCCTGGAGGGGATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCTCACAGCTTTGCCCTGTCTCTCTGTGGGACTTCGTTTGGCTGGGGA
AGTAACAGTGCCGGGCAGCTGGCCCTCAGTGGGCGTAATGTCCCAGTGCAAAGCAACAAGCCTCTCTCAGTCGGTGCACTGAAGAATCTAGGTGTGGTTT
ATATCAGCTGTGGTGATGCACACACTGCGGTGCTTACCCAGGACGGGAAAGTGTTCACATTTGGAGACAATCGCTCTGGACAGCTGGGATACAGCCCCAC
TCCTGAGAAGAGAGGTCCACAACTTGTGGAAAGAATTGATGGCCTAGTTTCGCAGATAGATTGTGGAAGTTATCACACCCTGGCATATGTGCACACCACT
GGTCAGGTGGTATCTTTTGGTCATGGACCAAGTGACACAAGCAAGCCAACTCATCCGGAGGCCCTGACAGAGAACTTTGACATTAGCTGCCTGATTTCTG
CTGAAGACTTCGTGGATGTTCAAGTCAAACACATTTTTGCTGGAACATATGCCAACTTTGTGACAACTCATCAGTGAAATTAGAATGATATTTTCATCTC
CTGCTTGTCTGACTGCAAGTTTTTTAAAGAAAAGAGGAACTGGAGAAACGACTTCCATTGATGTGGACTTAGAAATGGCAAGAGATACCTTCAAGAAGTT
AACAAAAAAGGAATGGATTTCTTCCATGATAACTACGTGTCTCGAGGATGATCTGCTCAGAGCTCTTCCATGCCATTCTCCACACCAAGAAGCTTTATCA
GTTTTCCTCCTGCTCCCAGAATGTCCTGTGATGCATGATTCTAAGAACTGGAAGAACCTGGTGGTTCCATTTGCAAAGGCTGTGTGTGAAATGAGTAAAC
AATCTTTGCAAGTCCTAAGTAAACAAAGCTAACTGTCGACTACCAGAAAATACTTTCAACATAAATGAACTCTCCAACTTATTAAACTTTTATATAGATA
GAGGAAGACAGCTCTTTCGGGATAACCACCTGATACCTGCAGAAACCCCCAGTCCTGTTATTTTCAGTGATTTTCCATTTATCTTTAATTCGCTATCCAA
AATTAAATTATTGCAAGCTGATTCACATATAAAGATGCAGGCTGGAGTACAATGGTGCAATCTCAGCTCACCACAACCTCTGCCTCCCGGGTTCAAGCGA
TTCTTCTGCCTCAGCCTCCCAAATGTCAGAAAAGAAAGCATACATGCTTATGCATGAAACAATTCTGCAAAAAAAGGATGAATTTCCTCCATCACCCAGA
TTTATACTTAGAGTCAGACGAAGTCGCCTGGTTAAAGATGCTCTGCGTCAATTAAGTCAAGCTGAAGCTACTGACTTCTGCAAAGTATTAGTGGTTGAAT
TTATTAATGAAATTTGTCCTGAGTCTGGAGGGGTTAGTTCAGAGTTCTTCCACTGTATGTTTGAAGAGATGACCAAGCCAGAATATGGAATGTTCATGTA
TCCTGAAATGGGTTCCTGCATGTGGTTTCCTGCCAAGCCTAAACCTGAGAAGAAAAGATATTTCCTCTTTGGAATGCTGTGTGGACTCTCCTTATTCAAT
TTAAATGTTGCTAACCTTCCTTTCCCACTGGCTCTGTATAAAAAACTTCTGGACCAAAAGCCATCATTGGAAGATTTAAAAGAACTCAGTCCTCGGTTGG
GGAAGAGTTTGCAAGAAGTTCTAGATGATGCTGCTGATGACATTGGAGATGCGCTCTGCATACGCTTTTCTATACACTGGGACCAAAATGATGTTGACTT
AATTCCAAATGGGATCTCCATACCTGTGGACCAAACCAACAAGAGAGACTATGTTTCTAAGTATATTGATTACATTTTCAACGTCTCTGTAAAAGCAGTT
TATGAGGAATTTCAGAGAGGATTTTATAGAGTCTGTGAGAAGGAGATACTTAGACATTTCTACCCTGAAGAACTAATGACAGCAATCATTGGAAATACTG
ATTATGACTGGAAACAGTTTGAACAGAATTCAAAGTATGAGCAAGGATACCAAAAATCACATCCTACTATACAGTTGTTTTGGAAGGCTTTCCACAAACT
AACCTTGGATGAAAAGAAAAAATTCCTCTTTTTCCTTACAGGACGTGATAGGCTGCATGCAAGAGGCATACAGAAAATGGAAATAGTATTTCGCTGTCCT
GAAACTTTCAGTGAAAGAGATCACCCAACATCAATAACTTGTCATAATATTCTCTCCCTCCCTAAGTATTCTACAATGGAAAGAATGGAGGAAGCACTTC
AAGTAGCCATCAACAACAACAGAGGATTTGTCTCACCCATGCTCACACAGTCATAATCACCTCTGAGAGACTCAGGGTGGGCTTTCTCACACTTGGATCC
TTCTGTTCTTCCTTACACCTAAATAATACAAGAGATTAATGAATAGTGGTTAGAAGTAGTTGAGGGAGAGATTGGGGGAATGGGGAGATGATGATGATGG
TCAAAGGGTGCAAAATCTCACACAAGACTGAGGCAGGAGAATAGGGTACAGAGATAGGGATCTAAGGATGACTTGGACACACTCCCTGGCACTGAAGAGT
CTGAACACTGGCCTGTGATTGGTCCATTCCAGGACCTTCATTTGCATAAGGTATCAAACCACATCAGCCTCTGATTGGCCATGGGCCAGACCTGCACTCT
GGCCAATGATTGGTTCATTCCAGGACATTCATTTGCATAAGGAGTCAAACCACACCAGTCTTGGATTGGCTGTGAGCCAATTCACCTCAGTCTCTAATTG
GCTGTGAGTCAGTCTTTCATTTACATAGGGTGTAACCATCAAGAAACCTCTACAGGGTACTTAAGCCCCAGAAGATTTTGCTACCAGGGCTCTTGAGCCA
CTTGCTCTAGCCCACTCCCACCCTGTGGAATGTACTTTCACTTTTGCTGCTTCACTGCCTTGTGCTCCAATAAATCCACTCCTTCACCACCCA
  • refseq_HERC6.F4 (forward primer)
  • refseq_HERC6.R3 (reverse primer)
  • Single exon skipping

Frame 0

ST*SSGSES*HGARAAPLGRVEDRVSLLIFRKS
SRTQSPAFGSLSQRDRRNPEQATGRRSGMYFCWG
ADSRELQRRRTAGSPGAELLQAASGERHSLLLL
TNHRVLSCGDNSRGQLGRRARSAGSCQNQFRHW
KP*LLIS*AAGRSTPWLCATKEGSSHGELVLKGS
WGLENSRK*VSHLRK**L*MI*K*YKFPVDTTT
PWHYQKIAKCFRGERTAMGSWAWGRSSPPKPAR
RG*GPWRGSHWLRWLPEGLTALPCLSVGLRLAGE
VTVPGSWPSVGVMSQCKATSLSQSVH*RI*VWF
ISAVVMHTLRCLPRTGKCSHLETIALDSWDTAP
LLRREVHNLWKELMA*FRR*IVEVITPWHMCTPL
VRWYLLVMDQVTQASQLIRRP*QRTLTLAA*FL
LKTSWMFKSNTFLLEHMPTL*QLISEIRMIFSS
PACLTASFLKKRGTGETTSIDVDLEMARDTFKKL
TKKEWISSMITTCLEDDLLRALPCHSPHQEALS
VFLLLPECPVMHDSKNWKNLVVPFAKAVCEMSK
QSLQVLSKQS*LSTTRKYFQHK*TLQLIKLLYR*
RKTALSG*PPDTCRNPQSCYFQ*FSIYL*FAIQ
N*IIAS*FTYKDAGWSTMVQSQLTTTSASRVQA
ILLPQPPKCQKRKHTCLCMKQFCKKRMNFLHHPD
LYLESDEVAWLKMLCVN*VKLKLLTSAKY*WLN
LLMKFVLSLEGLVQSSSTVCLKR*PSQNMECSC
ILKWVPACGFLPSLNLRRKDISSLECCVDSPYSI
*MLLTFLSHWLCIKNFWTKSHHWKI*KNSVLGW
GRVCKKF*MMLLMTLEMRSAYAFLYTGTKMMLT
*FQMGSPYLWTKPTRETMFLSILITFSTSL*KQF
MRNFREDFIESVRRRYLDISTLKN**QQSLEIL
IMTGNSLNRIQSMSKDTKNHILLYSCFGRLSTN
*PWMKRKNSSFSLQDVIGCMQEAYRKWK*YFAVL
KLSVKEITQHQ*LVIIFSPSLSILQWKEWRKHF
K*PSTTTEDLSHPCSHSHNHL*ETQGGLSHTWI
LLFFLTPK*YKRLMNSG*K*LRERLGEWGDDDDG
QRVQNLTQD*GRRIGYRDRDLRMTWTHSLALKS
LNTGL*LVHSRTFICIRYQTTSASDWPWARPAL
WPMIGSFQDIHLHKESNHTSLGLAVSQFTSVSNW
L*VSLSFT*GVTIKKPLQGT*APEDFATRALEP
LALAHSHPVECTFTFAASLPCAPINPLLHHP

Frame 1

ALEVQAARVDMGPGLRPWGGLKTG*VS*YSGNH
RAPSHQRSGACRSGTDGIRSRRQGAEAGCTSVG
APTPGSCSAGGRRAAPGLSYCRRPAGSATLCCC*
PTTGSSRAETTAGVSWAAGRAARGAARTNSGIG
NPNC*SRELREGALPGCVPQRKGLRMGSWF*RA
AGDWRIQGNKFHT*ENNDSE*YKNNTSFLWTLPL
PGIIKR*PSVFVGKEQPWAAGLGEGVPLPSQPA
EGEVPGGDPTGSGGCRRGSQLCPVSLWDFVWLG
K*QCRAAGPQWA*CPSAKQQASLSRCTEESRCGL
YQLW*CTHCGAYPGRESVHIWRQSLWTAGIQPH
S*EERSTTCGKN*WPSFADRLWKLSHPGICAHH
WSGGIFWSWTK*HKQANSSGGPDREL*H*LPDFC
*RLRGCSSQTHFCWNICQLCDNSSVKLE*YFHL
LLV*LQVF*RKEELEKRLPLMWT*KWQEIPSRS
*QKRNGFLP**LRVSRMICSELFHAILHTKKLYQ
FSSCSQNVL*CMILRTGRTWWFHLQRLCVK*VN
NLCKS*VNKANCRLPENTFNINELSNLLNFYID
RGRQLFRDNHLIPAETPSPVIFSDFPFIFNSLSK
IKLLQADSHIKMQAGVQWCNLSSPQPLPPGFKR
FFCLSLPNVRKESIHAYA*NNSAKKG*ISSITQ
IYT*SQTKSPG*RCSASIKSS*SY*LLQSISG*I
Y**NLS*VWRG*FRVLPLYV*RDDQARIWNVHV
S*NGFLHVVSCQA*T*EEKIFPLWNAVWTLLIQ
FKCC*PSFPTGSV*KTSGPKAIIGRFKRTQSSVG
EEFARSSR*CC**HWRCALHTLFYTLGPK*C*L
NSKWDLHTCGPNQQERLCF*VY*LHFQRLCKSS
L*GISERIL*SL*EGDT*TFLP*RTNDSNHWKY*
L*LETV*TEFKV*ARIPKITSYYTVVLEGFPQT
NLG*KEKIPLFPYRT**AACKRHTENGNSISLS
*NFQ*KRSPNINNLS*YSLPP*VFYNGKNGGSTS
SSHQQQQRICLTHAHTVIITSERLRVGFLTLGS
FCSSLHLNNTRD**IVVRSS*GRDWGNGEMMMM
VKGCKISHKTEAGE*GTEIGI*G*LGHTPWH*RV
*TLACDWSIPGPSFA*GIKPHQPLIGHGPDLHS
GQ*LVHSRTFICIRSQTTPVLDWL*ANSPQSLI
GCESVFHLHRV*PSRNLYRVLKPQKILLPGLLSH
LL*PTPTLWNVLSLLLLHCLVLQ*IHSFTT

Frame 2

HLKFRQRELTWGQGCAPGAG*RQGESLDIQEII
AHPVTSVREPVAAGPTESGAGDRAQKRDVLLLG
RRLQGAAAPEDGGQPRG*ATAGGQRGAPLSAAA
DQPQGPLVRRQQQGSAGPQGAQRGELPEPIQALE
TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQ
LGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH
SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ
RVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWG
SNSAGQLALSGRNVPVQSNKPLSVGALKNLGVV
YISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPT
PEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTT
GQVVSFGHGPSDTSKPTHPEALTENFDISCLIS
AEDFVDVQVKHIFAGTYANFVTTHQ*N*NDIFIS
CLSDCKFFKEKRNWRNDFH*CGLRNGKRYLQEV
NKKGMDFFHDNYVSRG*SAQSSSMPFSTPRSFI
SFPPAPRMSCDA*F*ELEEPGGSICKGCV*NE*T
IFASPK*TKLTVDYQKILST*MNSPTY*TFI*I
EEDSSFGITT*YLQKPPVLLFSVIFHLSLIRYP
KLNYCKLIHI*RCRLEYNGAISAHHNLCLPGSSD
SSASASQMSEKKAYMLMHETILQKKDEFPPSPR
FILRVRRSRLVKDALRQLSQAEATDFCKVLVVE
FINEICPESGGVSSEFFHCMFEEMTKPEYGMFMY
PEMGSCMWFPAKPKPEKKRYFLFGMLCGLSLFN
LNVANLPFPLALYKKLLDQKPSLEDLKELSPRL
GKSLQEVLDDAADDIGDALCIRFSIHWDQNDVDL
IPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAV
YEEFQRGFYRVCEKEILRHFYPEELMTAIIGNT
DYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKL
TLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCP
ETFSERDHPTSITCHNILSLPKYSTMERMEEAL
QVAINNNRGFVSPMLTQS*SPLRDSGWAFSHLDP
SVLPYT*IIQEINE*WLEVVEGEIGGMGR***W
SKGAKSHTRLRQENRVQR*GSKDDLDTLPGTEE
SEHWPVIGPFQDLHLHKVSNHISL*LAMGQTCTL
ANDWFIPGHSFA*GVKPHQSWIGCEPIHLSL*L
AVSQSFIYIGCNHQETSTGYLSPRRFCYQGS*A
TCSSPLPPCGMYFHFCCFTALCSNKSTPSPP

Sequence NM_001013000

AGCACTTGAAGTTCAGGCAGCGAGAGTTGACATGGGGCCAGGGCTGCGCCCCTGGGGCGGGTTGAAGACAGGGTGAGTCTCTTGATATTCAGGAAATCAT
CGCGCACCCAGTCACCAGCGTTCGGGAGCCTGTCGCAGCGGGACCGACGGAATCCGGAGCAGGCGACAGGGCGCAGAAGCGGGATGTACTTCTGTTGGGG
CGCCGACTCCAGGGAGCTGCAGCGCCGGAGGACGGCGGGCAGCCCCGGGGCTGAGCTACTGCAGGCGGCCAGCGGGGAGCGCCACTCTCTGCTGCTGCTG
ACCAACCACAGGGTCCTCTCGTGCGGAGACAACAGCAGGGGTCAGCTGGGCCGCAGGGCGCGCAGCGCGGGGAGCTGCCAGAACCAATTCAGGCATTGGA
AACCCTAATTGTTGATCTCGTGAGCTGCGGGAAGGAGCACTCCCTGGCTGTGTGCCACAAAGGAAGGGTCTTCGCATGGGGAGCTGGTTCTGAAGGGCAG
CTGGGGATTGGAGAATTCAAGGAAATAAGTTTCACACCTAAGAAAATAATGACTCTGAATGATATAAAAATAATACAAGTTTCCTGTGGACACTACCACT
CCCTGGCATTATCAAAAGATAGCCAAGTGTTTTCGTGGGGAAAGAACAGCCATGGGCAGCTGGGCTTGGGGAAGGAGTTCCCCTCCCAAGCCAGCCCGCA
GAGGGTGAGGTCCCTGGAGGGGATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCTCACAGCTTTGCCCTGTCTCTCTGTGGGACTTCGTTTGGCTGGGGA
AGTAACAGTGCCGGGCAGCTGGCCCTCAGTGGGCGTAATGTCCCAGTGCAAAGCAACAAGCCTCTCTCAGTCGGTGCACTGAAGAATCTAGGTGTGGTTT
ATATCAGCTGTGGTGATGCACACACTGCGGTGCTTACCCAGGACGGGAAAGTGTTCACATTTGGAGACAATCGCTCTGGACAGCTGGGATACAGCCCCAC
TCCTGAGAAGAGAGGTCCACAACTTGTGGAAAGAATTGATGGCCTAGTTTCGCAGATAGATTGTGGAAGACTTCGTGGATGTTCAAGTCAAACACATTTT
TGCTGGAACATATGCCAACTTTGTGACAACTCATCAGTGAAATTAGAATGATATTTTCATCTCCTGCTTGTCTGACTGCAAGTTTTTTAAAGAAAAGAGG
AACTGGAGAAACGACTTCCATTGATGTGGACTTAGAAATGGCAAGAGATACCTTCAAGAAGTTAACAAAAAAGGAATGGATTTCTTCCATGATAACTACG
TGTCTCGAGGATGATCTGCTCAGAGCTCTTCCATGCCATTCTCCACACCAAGAAGCTTTATCAGTTTTCCTCCTGCTCCCAGAATGTCCTGTGATGCATG
ATTCTAAGAACTGGAAGAACCTGGTGGTTCCATTTGCAAAGGCTGTGTGTGAAATGAGTAAACAATCTTTGCAAGTCCTAAGTAAACAAAGCTAACTGTC
GACTACCAGAAAATACTTTCAACATAAATGAACTCTCCAACTTATTAAACTTTTATATAGATAGAGGAAGACAGCTCTTTCGGGATAACCACCTGATACC
TGCAGAAACCCCCAGTCCTGTTATTTTCAGTGATTTTCCATTTATCTTTAATTCGCTATCCAAAATTAAATTATTGCAAGCTGATTCACATATAAAGATG
CAGATGTCAGAAAAGAAAGCATACATGCTTATGCATGAAACAATTCTGCAAAAAAAGGATGAATTTCCTCCATCACCCAGATTTATACTTAGAGTCAGAC
GAAGTCGCCTGGTTAAAGATGCTCTGCGTCAATTAAGTCAAGCTGAAGCTACTGACTTCTGCAAAGTATTAGTGGTTGAATTTATTAATGAAATTTGTCC
TGAGTCTGGAGGGGTTAGTTCAGAGTTCTTCCACTGTATGTTTGAAGAGATGACCAAGCCAGAATATGGAATGTTCATGTATCCTGAAATGGGTTCCTGC
ATGTGGTTTCCTGCCAAGCCTAAACCTGAGAAGAAAAGATATTTCCTCTTTGGAATGCTGTGTGGACTCTCCTTATTCAATTTAAATGTTGCTAACCTTC
CTTTCCCACTGGCTCTGTATAAAAAACTTCTGGACCAAAAGCCATCATTGGAAGATTTAAAAGAACTCAGTCCTCGGTTGGGGAAGAGTTTGCAAGAAGT
TCTAGATGATGCTGCTGATGACATTGGAGATGCGCTCTGCATACGCTTTTCTATACACTGGGACCAAAATGATGTTGACTTAATTCCAAATGGGATCTCC
ATACCTGTGGACCAAACCAACAAGAGAGACTATGTTTCTAAGTATATTGATTACATTTTCAACGTCTCTGTAAAAGCAGTTTATGAGGAATTTCAGAGAG
GATTTTATAGAGTCTGTGAGAAGGAGATACTTAGACATTTCTACCCTGAAGAACTAATGACAGCAATCATTGGAAATACTGATTATGACTGGAAACAGTT
TGAACAGAATTCAAAGTATGAGCAAGGATACCAAAAATCACATCCTACTATACAGTTGTTTTGGAAGGCTTTCCACAAACTAACCTTGGATGAAAAGAAA
AAATTCCTCTTTTTCCTTACAGGACGTGATAGGCTGCATGCAAGAGGCATACAGAAAATGGAAATAGTATTTCGCTGTCCTGAAACTTTCAGTGAAAGAG
ATCACCCAACATCAATAACTTGTCATAATATTCTCTCCCTCCCTAAGTATTCTACAATGGAAAGAATGGAGGAAGCACTTCAAGTAGCCATCAACAACAA
CAGAGGATTTGTCTCACCCATGCTCACACAGTCATAATCACCTCTGAGAGACTCAGGGTGGGCTTTCTCACACTTGGATCCTTCTGTTCTTCCTTACACC
TAAATAATACAAGAGATTAATGAATAGTGGTTAGAAGTAGTTGAGGGAGAGATTGGGGGAATGGGGAGATGATGATGATGGTCAAAGGGTGCAAAATCTC
ACACAAGACTGAGGCAGGAGAATAGGGTACAGAGATAGGGATCTAAGGATGACTTGGACACACTCCCTGGCACTGAAGAGTCTGAACACTGGCCTGTGAT
TGGTCCATTCCAGGACCTTCATTTGCATAAGGTATCAAACCACATCAGCCTCTGATTGGCCATGGGCCAGACCTGCACTCTGGCCAATGATTGGTTCATT
CCAGGACATTCATTTGCATAAGGAGTCAAACCACACCAGTCTTGGATTGGCTGTGAGCCAATTCACCTCAGTCTCTAATTGGCTGTGAGTCAGTCTTTCA
TTTACATAGGGTGTAACCATCAAGAAACCTCTACAGGGTACTTAAGCCCCAGAAGATTTTGCTACCAGGGCTCTTGAGCCACTTGCTCTAGCCCACTCCC
ACCCTGTGGAATGTACTTTCACTTTTGCTGCTTCACTGCCTTGTGCTCCAATAAATCCACTCCTTCACCACCCA
  • refseq_HERC6.F4 (forward primer)
  • refseq_HERC6.R3 (reverse primer)
  • Single exon skipping

Frame 0

ST*SSGSES*HGARAAPLGRVEDRVSLLIFRKS
SRTQSPAFGSLSQRDRRNPEQATGRRSGMYFCWG
ADSRELQRRRTAGSPGAELLQAASGERHSLLLL
TNHRVLSCGDNSRGQLGRRARSAGSCQNQFRHW
KP*LLIS*AAGRSTPWLCATKEGSSHGELVLKGS
WGLENSRK*VSHLRK**L*MI*K*YKFPVDTTT
PWHYQKIAKCFRGERTAMGSWAWGRSSPPKPAR
RG*GPWRGSHWLRWLPEGLTALPCLSVGLRLAGE
VTVPGSWPSVGVMSQCKATSLSQSVH*RI*VWF
ISAVVMHTLRCLPRTGKCSHLETIALDSWDTAP
LLRREVHNLWKELMA*FRR*IVEDFVDVQVKHIF
AGTYANFVTTHQ*N*NDIFISCLSDCKFFKEKR
NWRNDFH*CGLRNGKRYLQEVNKKGMDFFHDNY
VSRG*SAQSSSMPFSTPRSFISFPPAPRMSCDA*
F*ELEEPGGSICKGCV*NE*TIFASPK*TKLTV
DYQKILST*MNSPTY*TFI*IEEDSSFGITT*Y
LQKPPVLLFSVIFHLSLIRYPKLNYCKLIHI*RC
RCQKRKHTCLCMKQFCKKRMNFLHHPDLYLESD
EVAWLKMLCVN*VKLKLLTSAKY*WLNLLMKFV
LSLEGLVQSSSTVCLKR*PSQNMECSCILKWVPA
CGFLPSLNLRRKDISSLECCVDSPYSI*MLLTF
LSHWLCIKNFWTKSHHWKI*KNSVLGWGRVCKK
F*MMLLMTLEMRSAYAFLYTGTKMMLT*FQMGSP
YLWTKPTRETMFLSILITFSTSL*KQFMRNFRE
DFIESVRRRYLDISTLKN**QQSLEILIMTGNS
LNRIQSMSKDTKNHILLYSCFGRLSTN*PWMKRK
NSSFSLQDVIGCMQEAYRKWK*YFAVLKLSVKE
ITQHQ*LVIIFSPSLSILQWKEWRKHFK*PSTT
TEDLSHPCSHSHNHL*ETQGGLSHTWILLFFLTP
K*YKRLMNSG*K*LRERLGEWGDDDDGQRVQNL
TQD*GRRIGYRDRDLRMTWTHSLALKSLNTGL*
LVHSRTFICIRYQTTSASDWPWARPALWPMIGSF
QDIHLHKESNHTSLGLAVSQFTSVSNWL*VSLS
FT*GVTIKKPLQGT*APEDFATRALEPLALAHS
HPVECTFTFAASLPCAPINPLLHHP

Frame 1

ALEVQAARVDMGPGLRPWGGLKTG*VS*YSGNH
RAPSHQRSGACRSGTDGIRSRRQGAEAGCTSVG
APTPGSCSAGGRRAAPGLSYCRRPAGSATLCCC*
PTTGSSRAETTAGVSWAAGRAARGAARTNSGIG
NPNC*SRELREGALPGCVPQRKGLRMGSWF*RA
AGDWRIQGNKFHT*ENNDSE*YKNNTSFLWTLPL
PGIIKR*PSVFVGKEQPWAAGLGEGVPLPSQPA
EGEVPGGDPTGSGGCRRGSQLCPVSLWDFVWLG
K*QCRAAGPQWA*CPSAKQQASLSRCTEESRCGL
YQLW*CTHCGAYPGRESVHIWRQSLWTAGIQPH
S*EERSTTCGKN*WPSFADRLWKTSWMFKSNTF
LLEHMPTL*QLISEIRMIFSSPACLTASFLKKRG
TGETTSIDVDLEMARDTFKKLTKKEWISSMITT
CLEDDLLRALPCHSPHQEALSVFLLLPECPVMH
DSKNWKNLVVPFAKAVCEMSKQSLQVLSKQS*LS
TTRKYFQHK*TLQLIKLLYR*RKTALSG*PPDT
CRNPQSCYFQ*FSIYL*FAIQN*IIAS*FTYKD
ADVRKESIHAYA*NNSAKKG*ISSITQIYT*SQT
KSPG*RCSASIKSS*SY*LLQSISG*IY**NLS
*VWRG*FRVLPLYV*RDDQARIWNVHVS*NGFL
HVVSCQA*T*EEKIFPLWNAVWTLLIQFKCC*PS
FPTGSV*KTSGPKAIIGRFKRTQSSVGEEFARS
SR*CC**HWRCALHTLFYTLGPK*C*LNSKWDL
HTCGPNQQERLCF*VY*LHFQRLCKSSL*GISER
IL*SL*EGDT*TFLP*RTNDSNHWKY*L*LETV
*TEFKV*ARIPKITSYYTVVLEGFPQTNLG*KE
KIPLFPYRT**AACKRHTENGNSISLS*NFQ*KR
SPNINNLS*YSLPP*VFYNGKNGGSTSSSHQQQ
QRICLTHAHTVIITSERLRVGFLTLGSFCSSLH
LNNTRD**IVVRSS*GRDWGNGEMMMMVKGCKIS
HKTEAGE*GTEIGI*G*LGHTPWH*RV*TLACD
WSIPGPSFA*GIKPHQPLIGHGPDLHSGQ*LVH
SRTFICIRSQTTPVLDWL*ANSPQSLIGCESVFH
LHRV*PSRNLYRVLKPQKILLPGLLSHLL*PTP
TLWNVLSLLLLHCLVLQ*IHSFTT

Frame 2

HLKFRQRELTWGQGCAPGAG*RQGESLDIQEII
AHPVTSVREPVAAGPTESGAGDRAQKRDVLLLG
RRLQGAAAPEDGGQPRG*ATAGGQRGAPLSAAA
DQPQGPLVRRQQQGSAGPQGAQRGELPEPIQALE
TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQ
LGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH
SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ
RVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWG
SNSAGQLALSGRNVPVQSNKPLSVGALKNLGVV
YISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPT
PEKRGPQLVERIDGLVSQIDCGRLRGCSSQTHF
CWNICQLCDNSSVKLE*YFHLLLV*LQVF*RKE
ELEKRLPLMWT*KWQEIPSRS*QKRNGFLP**LR
VSRMICSELFHAILHTKKLYQFSSCSQNVL*CM
ILRTGRTWWFHLQRLCVK*VNNLCKS*VNKANC
RLPENTFNINELSNLLNFYIDRGRQLFRDNHLIP
AETPSPVIFSDFPFIFNSLSKIKLLQADSHIKM
QMSEKKAYMLMHETILQKKDEFPPSPRFILRVR
RSRLVKDALRQLSQAEATDFCKVLVVEFINEICP
ESGGVSSEFFHCMFEEMTKPEYGMFMYPEMGSC
MWFPAKPKPEKKRYFLFGMLCGLSLFNLNVANL
PFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEV
LDDAADDIGDALCIRFSIHWDQNDVDLIPNGIS
IPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQR
GFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQF
EQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKK
KFLFFLTGRDRLHARGIQKMEIVFRCPETFSER
DHPTSITCHNILSLPKYSTMERMEEALQVAINNN
RGFVSPMLTQS*SPLRDSGWAFSHLDPSVLPYT
*IIQEINE*WLEVVEGEIGGMGR***WSKGAKS
HTRLRQENRVQR*GSKDDLDTLPGTEESEHWPVI
GPFQDLHLHKVSNHISL*LAMGQTCTLANDWFI
PGHSFA*GVKPHQSWIGCEPIHLSL*LAVSQSF
IYIGCNHQETSTGYLSPRRFCYQGS*ATCSSPLP
PCGMYFHFCCFTALCSNKSTPSPP

Sequence NM_017912

AGCACTTGAAGTTCAGGCAGCGAGAGTTGACATGGGGCCAGGGCTGCGCCCCTGGGGCGGGTTGAAGACAGGGTGAGTCTCTTGATATTCAGGAAATCAT
CGCGCACCCAGTCACCAGCGTTCGGGAGCCTGTCGCAGCGGGACCGACGGAATCCGGAGCAGGCGACAGGGCGCAGAAGCGGGATGTACTTCTGTTGGGG
CGCCGACTCCAGGGAGCTGCAGCGCCGGAGGACGGCGGGCAGCCCCGGGGCTGAGCTACTGCAGGCGGCCAGCGGGGAGCGCCACTCTCTGCTGCTGCTG
ACCAACCACAGGGTCCTCTCGTGCGGAGACAACAGCAGGGGTCAGCTGGGCCGCAGGGCGCGCAGCGCGGGGAGCTGCCAGAACCAATTCAGGCATTGGA
AACCCTAATTGTTGATCTCGTGAGCTGCGGGAAGGAGCACTCCCTGGCTGTGTGCCACAAAGGAAGGGTCTTCGCATGGGGAGCTGGTTCTGAAGGGCAG
CTGGGGATTGGAGAATTCAAGGAAATAAGTTTCACACCTAAGAAAATAATGACTCTGAATGATATAAAAATAATACAAGTTTCCTGTGGACACTACCACT
CCCTGGCATTATCAAAAGATAGCCAAGTGTTTTCGTGGGGAAAGAACAGCCATGGGCAGCTGGGCTTGGGGAAGGAGTTCCCCTCCCAAGCCAGCCCGCA
GAGGGTGAGGTCCCTGGAGGGGATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCTCACAGCTTTGCCCTGTCTCTCTGTGGGACTTCGTTTGGCTGGGGA
AGTAACAGTGCCGGGCAGCTGGCCCTCAGTGGGCGTAATGTCCCAGTGCAAAGCAACAAGCCTCTCTCAGTCGGTGCACTGAAGAATCTAGGTGTGGTTT
ATATCAGCTGTGGTGATGCACACACTGCGGTGCTTACCCAGGACGGGAAAGTGTTCACATTTGGAGACAATCGCTCTGGACAGCTGGGATACAGCCCCAC
TCCTGAGAAGAGAGGTCCACAACTTGTGGAAAGAATTGATGGCCTAGTTTCGCAGATAGATTGTGGAAGTTATCACACCCTGGCATATGTGCACACCACT
GGTCAGGTGGTATCTTTTGGTCATGGACCAAGTGACACAAGCAAGCCAACTCATCCGGAGGCCCTGACAGAGAACTTTGACATTAGCTGCCTGATTTCTG
CTGAAGACTTCGTGGATGTTCAAGTCAAACACATTTTTGCTGGAACATATGCCAACTTTGTGACAACTCATCAGGATACTAGTTCCACACGTGCTCCCGG
GAAAACCCTGCCAGAAATAAGCCGAATTAGCCAGTCCATGGCAGAAAAATGGATAGCAGTGAAAAGAAGAAGTACTGAACATGAAATGGCTAAAAGTGAA
ATTAGAATGATATTTTCATCTCCTGCTTGTCTGACTGCAAGTTTTTTAAAGAAAAGAGGAACTGGAGAAACGACTTCCATTGATGTGGACTTAGAAATGG
CAAGAGATACCTTCAAGAAGTTAACAAAAAAGGAATGGATTTCTTCCATGATAACTACGTGTCTCGAGGATGATCTGCTCAGAGCTCTTCCATGCCATTC
TCCACACCAAGAAGCTTTATCAGTTTTCCTCCTGCTCCCAGAATGTCCTGTGATGCATGATTCTAAGAACTGGAAGAACCTGGTGGTTCCATTTGCAAAG
GCTGTGTGTGAAATGAGTAAACAATCTTTGCAAGTCCTAAAGAAGTGTTGGGCATTTTTGCAAGAATCTTCTCTGAATCCGCTGATCCAGATGCTTAAAG
CAGCCATCATCTCTCAGCTGCTTCATCAGACTAAAACCGAACAGGATCACTGTAATGTTAAAGCTCTTTTAGGAATGATGAAAGAACTGCATAAGGTAAA
CAAAGCTAACTGTCGACTACCAGAAAATACTTTCAACATAAATGAACTCTCCAACTTATTAAACTTTTATATAGATAGAGGAAGACAGCTCTTTCGGGAT
AACCACCTGATACCTGCAGAAACCCCCAGTCCTGTTATTTTCAGTGATTTTCCATTTATCTTTAATTCGCTATCCAAAATTAAATTATTGCAAGCTGATT
CACATATAAAGATGCAGATGTCAGAAAAGAAAGCATACATGCTTATGCATGAAACAATTCTGCAAAAAAAGGATGAATTTCCTCCATCACCCAGATTTAT
ACTTAGAGTCAGACGAAGTCGCCTGGTTAAAGATGCTCTGCGTCAATTAAGTCAAGCTGAAGCTACTGACTTCTGCAAAGTATTAGTGGTTGAATTTATT
AATGAAATTTGTCCTGAGTCTGGAGGGGTTAGTTCAGAGTTCTTCCACTGTATGTTTGAAGAGATGACCAAGCCAGAATATGGAATGTTCATGTATCCTG
AAATGGGTTCCTGCATGTGGTTTCCTGCCAAGCCTAAACCTGAGAAGAAAAGATATTTCCTCTTTGGAATGCTGTGTGGACTCTCCTTATTCAATTTAAA
TGTTGCTAACCTTCCTTTCCCACTGGCTCTGTATAAAAAACTTCTGGACCAAAAGCCATCATTGGAAGATTTAAAAGAACTCAGTCCTCGGTTGGGGAAG
AGTTTGCAAGAAGTTCTAGATGATGCTGCTGATGACATTGGAGATGCGCTCTGCATACGCTTTTCTATACACTGGGACCAAAATGATGTTGACTTAATTC
CAAATGGGATCTCCATACCTGTGGACCAAACCAACAAGAGAGACTATGTTTCTAAGTATATTGATTACATTTTCAACGTCTCTGTAAAAGCAGTTTATGA
GGAATTTCAGAGAGGATTTTATAGAGTCTGTGAGAAGGAGATACTTAGACATTTCTACCCTGAAGAACTAATGACAGCAATCATTGGAAATACTGATTAT
GACTGGAAACAGTTTGAACAGAATTCAAAGTATGAGCAAGGATACCAAAAATCACATCCTACTATACAGTTGTTTTGGAAGGCTTTCCACAAACTAACCT
TGGATGAAAAGAAAAAATTCCTCTTTTTCCTTACAGGACGTGATAGGCTGCATGCAAGAGGCATACAGAAAATGGAAATAGTATTTCGCTGTCCTGAAAC
TTTCAGTGAAAGAGATCACCCAACATCAATAACTTGTCATAATATTCTCTCCCTCCCTAAGTATTCTACAATGGAAAGAATGGAGGAAGCACTTCAAGTA
GCCATCAACAACAACAGAGGATTTGTCTCACCCATGCTCACACAGTCATAATCACCTCTGAGAGACTCAGGGTGGGCTTTCTCACACTTGGATCCTTCTG
TTCTTCCTTACACCTAAATAATACAAGAGATTAATGAATAGTGGTTAGAAGTAGTTGAGGGAGAGATTGGGGGAATGGGGAGATGATGATGATGGTCAAA
GGGTGCAAAATCTCACACAAGACTGAGGCAGGAGAATAGGGTACAGAGATAGGGATCTAAGGATGACTTGGACACACTCCCTGGCACTGAAGAGTCTGAA
CACTGGCCTGTGATTGGTCCATTCCAGGACCTTCATTTGCATAAGGTATCAAACCACATCAGCCTCTGATTGGCCATGGGCCAGACCTGCACTCTGGCCA
ATGATTGGTTCATTCCAGGACATTCATTTGCATAAGGAGTCAAACCACACCAGTCTTGGATTGGCTGTGAGCCAATTCACCTCAGTCTCTAATTGGCTGT
GAGTCAGTCTTTCATTTACATAGGGTGTAACCATCAAGAAACCTCTACAGGGTACTTAAGCCCCAGAAGATTTTGCTACCAGGGCTCTTGAGCCACTTGC
TCTAGCCCACTCCCACCCTGTGGAATGTACTTTCACTTTTGCTGCTTCACTGCCTTGTGCTCCAATAAATCCACTCCTTCACCACCCA
  • refseq_HERC6.F4 (forward primer)
  • refseq_HERC6.R3 (reverse primer)
  • Single exon skipping

Frame 0

ST*SSGSES*HGARAAPLGRVEDRVSLLIFRKS
SRTQSPAFGSLSQRDRRNPEQATGRRSGMYFCWG
ADSRELQRRRTAGSPGAELLQAASGERHSLLLL
TNHRVLSCGDNSRGQLGRRARSAGSCQNQFRHW
KP*LLIS*AAGRSTPWLCATKEGSSHGELVLKGS
WGLENSRK*VSHLRK**L*MI*K*YKFPVDTTT
PWHYQKIAKCFRGERTAMGSWAWGRSSPPKPAR
RG*GPWRGSHWLRWLPEGLTALPCLSVGLRLAGE
VTVPGSWPSVGVMSQCKATSLSQSVH*RI*VWF
ISAVVMHTLRCLPRTGKCSHLETIALDSWDTAP
LLRREVHNLWKELMA*FRR*IVEVITPWHMCTPL
VRWYLLVMDQVTQASQLIRRP*QRTLTLAA*FL
LKTSWMFKSNTFLLEHMPTL*QLIRILVPHVLP
GKPCQK*AELASPWQKNG*Q*KEEVLNMKWLKVK
LE*YFHLLLV*LQVF*RKEELEKRLPLMWT*KW
QEIPSRS*QKRNGFLP**LRVSRMICSELFHAI
LHTKKLYQFSSCSQNVL*CMILRTGRTWWFHLQR
LCVK*VNNLCKS*RSVGHFCKNLL*IR*SRCLK
QPSSLSCFIRLKPNRITVMLKLF*E**KNCIR*
TKLTVDYQKILST*MNSPTY*TFI*IEEDSSFGI
TT*YLQKPPVLLFSVIFHLSLIRYPKLNYCKLI
HI*RCRCQKRKHTCLCMKQFCKKRMNFLHHPDL
YLESDEVAWLKMLCVN*VKLKLLTSAKY*WLNLL
MKFVLSLEGLVQSSSTVCLKR*PSQNMECSCIL
KWVPACGFLPSLNLRRKDISSLECCVDSPYSI*
MLLTFLSHWLCIKNFWTKSHHWKI*KNSVLGWGR
VCKKF*MMLLMTLEMRSAYAFLYTGTKMMLT*F
QMGSPYLWTKPTRETMFLSILITFSTSL*KQFM
RNFREDFIESVRRRYLDISTLKN**QQSLEILIM
TGNSLNRIQSMSKDTKNHILLYSCFGRLSTN*P
WMKRKNSSFSLQDVIGCMQEAYRKWK*YFAVLK
LSVKEITQHQ*LVIIFSPSLSILQWKEWRKHFK*
PSTTTEDLSHPCSHSHNHL*ETQGGLSHTWILL
FFLTPK*YKRLMNSG*K*LRERLGEWGDDDDGQ
RVQNLTQD*GRRIGYRDRDLRMTWTHSLALKSLN
TGL*LVHSRTFICIRYQTTSASDWPWARPALWP
MIGSFQDIHLHKESNHTSLGLAVSQFTSVSNWL
*VSLSFT*GVTIKKPLQGT*APEDFATRALEPLA
LAHSHPVECTFTFAASLPCAPINPLLHHP

Frame 1

ALEVQAARVDMGPGLRPWGGLKTG*VS*YSGNH
RAPSHQRSGACRSGTDGIRSRRQGAEAGCTSVG
APTPGSCSAGGRRAAPGLSYCRRPAGSATLCCC*
PTTGSSRAETTAGVSWAAGRAARGAARTNSGIG
NPNC*SRELREGALPGCVPQRKGLRMGSWF*RA
AGDWRIQGNKFHT*ENNDSE*YKNNTSFLWTLPL
PGIIKR*PSVFVGKEQPWAAGLGEGVPLPSQPA
EGEVPGGDPTGSGGCRRGSQLCPVSLWDFVWLG
K*QCRAAGPQWA*CPSAKQQASLSRCTEESRCGL
YQLW*CTHCGAYPGRESVHIWRQSLWTAGIQPH
S*EERSTTCGKN*WPSFADRLWKLSHPGICAHH
WSGGIFWSWTK*HKQANSSGGPDREL*H*LPDFC
*RLRGCSSQTHFCWNICQLCDNSSGY*FHTCSR
ENPARNKPN*PVHGRKMDSSEKKKY*T*NG*K*
N*NDIFISCLSDCKFFKEKRNWRNDFH*CGLRNG
KRYLQEVNKKGMDFFHDNYVSRG*SAQSSSMPF
STPRSFISFPPAPRMSCDA*F*ELEEPGGSICK
GCV*NE*TIFASPKEVLGIFARIFSESADPDA*S
SHHLSAASSD*NRTGSL*C*SSFRNDERTA*GK
QS*LSTTRKYFQHK*TLQLIKLLYR*RKTALSG
*PPDTCRNPQSCYFQ*FSIYL*FAIQN*IIAS*F
TYKDADVRKESIHAYA*NNSAKKG*ISSITQIY
T*SQTKSPG*RCSASIKSS*SY*LLQSISG*IY
**NLS*VWRG*FRVLPLYV*RDDQARIWNVHVS*
NGFLHVVSCQA*T*EEKIFPLWNAVWTLLIQFK
CC*PSFPTGSV*KTSGPKAIIGRFKRTQSSVGE
EFARSSR*CC**HWRCALHTLFYTLGPK*C*LNS
KWDLHTCGPNQQERLCF*VY*LHFQRLCKSSL*
GISERIL*SL*EGDT*TFLP*RTNDSNHWKY*L
*LETV*TEFKV*ARIPKITSYYTVVLEGFPQTNL
G*KEKIPLFPYRT**AACKRHTENGNSISLS*N
FQ*KRSPNINNLS*YSLPP*VFYNGKNGGSTSS
SHQQQQRICLTHAHTVIITSERLRVGFLTLGSFC
SSLHLNNTRD**IVVRSS*GRDWGNGEMMMMVK
GCKISHKTEAGE*GTEIGI*G*LGHTPWH*RV*
TLACDWSIPGPSFA*GIKPHQPLIGHGPDLHSGQ
*LVHSRTFICIRSQTTPVLDWL*ANSPQSLIGC
ESVFHLHRV*PSRNLYRVLKPQKILLPGLLSHL
L*PTPTLWNVLSLLLLHCLVLQ*IHSFTT

Frame 2

HLKFRQRELTWGQGCAPGAG*RQGESLDIQEII
AHPVTSVREPVAAGPTESGAGDRAQKRDVLLLG
RRLQGAAAPEDGGQPRG*ATAGGQRGAPLSAAA
DQPQGPLVRRQQQGSAGPQGAQRGELPEPIQALE
TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQ
LGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH
SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ
RVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWG
SNSAGQLALSGRNVPVQSNKPLSVGALKNLGVV
YISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPT
PEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTT
GQVVSFGHGPSDTSKPTHPEALTENFDISCLIS
AEDFVDVQVKHIFAGTYANFVTTHQDTSSTRAPG
KTLPEISRISQSMAEKWIAVKRRSTEHEMAKSE
IRMIFSSPACLTASFLKKRGTGETTSIDVDLEM
ARDTFKKLTKKEWISSMITTCLEDDLLRALPCHS
PHQEALSVFLLLPECPVMHDSKNWKNLVVPFAK
AVCEMSKQSLQVLKKCWAFLQESSLNPLIQMLK
AAIISQLLHQTKTEQDHCNVKALLGMMKELHKVN
KANCRLPENTFNINELSNLLNFYIDRGRQLFRD
NHLIPAETPSPVIFSDFPFIFNSLSKIKLLQAD
SHIKMQMSEKKAYMLMHETILQKKDEFPPSPRFI
LRVRRSRLVKDALRQLSQAEATDFCKVLVVEFI
NEICPESGGVSSEFFHCMFEEMTKPEYGMFMYP
EMGSCMWFPAKPKPEKKRYFLFGMLCGLSLFNLN
VANLPFPLALYKKLLDQKPSLEDLKELSPRLGK
SLQEVLDDAADDIGDALCIRFSIHWDQNDVDLI
PNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYE
EFQRGFYRVCEKEILRHFYPEELMTAIIGNTDY
DWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLT
LDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPET
FSERDHPTSITCHNILSLPKYSTMERMEEALQV
AINNNRGFVSPMLTQS*SPLRDSGWAFSHLDPS
VLPYT*IIQEINE*WLEVVEGEIGGMGR***WSK
GAKSHTRLRQENRVQR*GSKDDLDTLPGTEESE
HWPVIGPFQDLHLHKVSNHISL*LAMGQTCTLA
NDWFIPGHSFA*GVKPHQSWIGCEPIHLSL*LAV
SQSFIYIGCNHQETSTGYLSPRRFCYQGS*ATC
SSPLPPCGMYFHFCCFTALCSNKSTPSPP

Sequence NM_001013002

AGCACTTGAAGTTCAGGCAGCGAGAGTTGACATGGGGCCAGGGCTGCGCCCCTGGGGCGGGTTGAAGACAGGGTGAGTCTCTTGATATTCAGGAAATCAT
CGCGCACCCAGTCACCAGCGTTCGGGAGCCTGTCGCAGCGGGACCGACGGAATCCGGAGCAGGCGACAGGGCGCAGAAGCGGGATGTACTTCTGTTGGGG
CGCCGACTCCAGGGAGCTGCAGCGCCGGAGGACGGCGGGCAGCCCCGGGGCTGAGCTACTGCAGGCGGCCAGCGGGGAGCGCCACTCTCTGCTGCTGCTG
ACCAACCACAGGGTCCTCTCGTGCGGAGACAACAGCAGGGGTCAGCTGGGCCGCAGGGCGCGCAGCGCGGGGAGCTGCCAGAACCAATTCAGGCATTGGA
AACCCTAATTGTTGATCTCGTGAGCTGCGGGAAGGAGCACTCCCTGGCTGTGTGCCACAAAGGAAGGGTCTTCGCATGGGGAGCTGGTTCTGAAGGGCAG
CTGGGGATTGGAGAATTCAAGGAAATAAGTTTCACACCTAAGAAAATAATGACTCTGAATGATATAAAAATAATACAAGTTTCCTGTGGACACTACCACT
CCCTGGCATTATCAAAAGATAGCCAAGTGTTTTCGTGGGGAAAGAACAGCCATGGGCAGCTGGGCTTGGGGAAGGAGTTCCCCTCCCAAGCCAGCCCGCA
GAGGGTGAGGTCCCTGGAGGGGATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCTCACAGCTTTGCCCTGTCTCTCTGTGGGACTTCGTTTGGCTGGGGA
AGTAACAGTGCCGGGCAGCTGGCCCTCAGTGGGCGTAATGTCCCAGTGCAAAGCAACAAGCCTCTCTCAGTCGGTGCACTGAAGAATCTAGGTGTGGTTT
ATATCAGCTGTGGTGATGCACACACTGCGGTGCTTACCCAGGACGGGAAAGTGTTCACATTTGGAGACAATCGCTCTGGACAGCTGGGATACAGCCCCAC
TCCTGAGAAGAGAGGTCCACAACTTGTGGAAAGAATTGATGGCCTAGTTTCGCAGATAGATTGTGGAAGTTATCACACCCTGGCATATGTGCACACCACT
GGTCAGGTGGTATCTTTTGGTCATGGACCAAGTGACACAAGCAAGCCAACTCATCCGGAGGCCCTGACAGAGAACTTTGACATTAGCTGCCTGATTTCTG
CTGAAGACTTCGTGGATGTTCAAGTCAAACACATTTTTGCTGGAACATATGCCAACTTTGTGACAACTCATCAGGATACTAGTTCCACACGTGCTCCCGG
GAAAACCCTGCCAGAAATAAGCCGAATTAGCCAGTCCATGGCAGAAAAATGGATAGCAGTGAAAAGAAGAAGTACTGAACATGAAATGGCTAAAAGTGAA
ATTAGAATGATATTTTCATCTCCTGCTTGTCTGACTGCAAGTTTTTTAAAGAAAAGAGGAACTGGAGAAACGACTTCCATTGATGTGGACTTAGAAATGG
CAAGAGATACCTTCAAGAAGTTAACAAAAAAGGAATGGATTTCTTCCATGATAACTACGTGTCTCGAGGATGATCTGCTCAGAGCTCTTCCATGCCATTC
TCCACACCAAGAAGCTTTATCAGTTTTCCTCCTGCTCCCAGAATGTCCTGTGATGCATGATTCTAAGAACTGGAAGAACCTGGTGGTTCCATTTGCAAAG
GCTGTGTGTGAAATGAGTAAACAATCTTTGCAAGTCCTAAAGAAGTGTTGGGCATTTTTGCAAGAATCTTCTCTGAATCCGCTGATCCAGATGCTTAAAG
CAGCCATCATCTCTCAGCTGCTTCATCAGACTAAAACCGAACAGGATCACTGTAATGTTAAAGCTCTTTTAGGAATGATGAAAGAACTGCATAAGGTAAA
CAAAGCTAACTGTCGACTACCAGAAAATACTTTCAACATAAATGAACTCTCCAACTTATTAAACTTTTATATAGATAGAGGAAGACAGCTCTTTCGGGAT
AACCACCTGATGTCAGAAAAGAAAGCATACATGCTTATGCATGAAACAATTCTGCAAAAAAAGGATGAATTTCCTCCATCACCCAGATTTATACTTAGAG
TCAGACGAAGTCGCCTGGTTAAAGATGCTCTGCGTCAATTAAGTCAAGCTGAAGCTACTGACTTCTGCAAAGTATTAGTGGTTGAATTTATTAATGAAAT
TTGTCCTGAGTCTGGAGGGGTTAGTTCAGAGTTCTTCCACTGTATGTTTGAAGAGATGACCAAGCCAGAATATGGAATGTTCATGTATCCTGAAATGGGT
TCCTGCATGTGGTTTCCTGCCAAGCCTAAACCTGAGAAGAAAAGATATTTCCTCTTTGGAATGCTGTGTGGACTCTCCTTATTCAATTTAAATGTTGCTA
ACCTTCCTTTCCCACTGGCTCTGTATAAAAAACTTCTGGACCAAAAGCCATCATTGGAAGATTTAAAAGAACTCAGTCCTCGGTTGGGGAAGAGTTTGCA
AGAAGTTCTAGATGATGCTGCTGATGACATTGGAGATGCGCTCTGCATACGCTTTTCTATACACTGGGACCAAAATGATGTTGACTTAATTCCAAATGGG
ATCTCCATACCTGTGGACCAAACCAACAAGAGAGACTATGTTTCTAAGTATATTGATTACATTTTCAACGTCTCTGTAAAAGCAGTTTATGAGGAATTTC
AGAGAGGATTTTATAGAGTCTGTGAGAAGGAGATACTTAGACATTTCTACCCTGAAGAACTAATGACAGCAATCATTGGAAATACTGATTATGACTGGAA
ACAGTTTGAACAGAATTCAAAGTATGAGCAAGGATACCAAAAATCACATCCTACTATACAGTTGTTTTGGAAGGCTTTCCACAAACTAACCTTGGATGAA
AAGAAAAAATTCCTCTTTTTCCTTACAGGACGTGATAGGCTGCATGCAAGAGGCATACAGAAAATGGAAATAGTATTTCGCTGTCCTGAAACTTTCAGTG
AAAGAGATCACCCAACATCAATAACTTGTCATAATATTCTCTCCCTCCCTAAGTATTCTACAATGGAAAGAATGGAGGAAGCACTTCAAGTAGCCATCAA
CAACAACAGAGGATTTGTCTCACCCATGCTCACACAGTCATAATCACCTCTGAGAGACTCAGGGTGGGCTTTCTCACACTTGGATCCTTCTGTTCTTCCT
TACACCTAAATAATACAAGAGATTAATGAATAGTGGTTAGAAGTAGTTGAGGGAGAGATTGGGGGAATGGGGAGATGATGATGATGGTCAAAGGGTGCAA
AATCTCACACAAGACTGAGGCAGGAGAATAGGGTACAGAGATAGGGATCTAAGGATGACTTGGACACACTCCCTGGCACTGAAGAGTCTGAACACTGGCC
TGTGATTGGTCCATTCCAGGACCTTCATTTGCATAAGGTATCAAACCACATCAGCCTCTGATTGGCCATGGGCCAGACCTGCACTCTGGCCAATGATTGG
TTCATTCCAGGACATTCATTTGCATAAGGAGTCAAACCACACCAGTCTTGGATTGGCTGTGAGCCAATTCACCTCAGTCTCTAATTGGCTGTGAGTCAGT
CTTTCATTTACATAGGGTGTAACCATCAAGAAACCTCTACAGGGTACTTAAGCCCCAGAAGATTTTGCTACCAGGGCTCTTGAGCCACTTGCTCTAGCCC
ACTCCCACCCTGTGGAATGTACTTTCACTTTTGCTGCTTCACTGCCTTGTGCTCCAATAAATCCACTCCTTCACCACCCA
  • refseq_HERC6.F4 (forward primer)
  • refseq_HERC6.R3 (reverse primer)
  • Single exon skipping

Frame 0

ST*SSGSES*HGARAAPLGRVEDRVSLLIFRKS
SRTQSPAFGSLSQRDRRNPEQATGRRSGMYFCWG
ADSRELQRRRTAGSPGAELLQAASGERHSLLLL
TNHRVLSCGDNSRGQLGRRARSAGSCQNQFRHW
KP*LLIS*AAGRSTPWLCATKEGSSHGELVLKGS
WGLENSRK*VSHLRK**L*MI*K*YKFPVDTTT
PWHYQKIAKCFRGERTAMGSWAWGRSSPPKPAR
RG*GPWRGSHWLRWLPEGLTALPCLSVGLRLAGE
VTVPGSWPSVGVMSQCKATSLSQSVH*RI*VWF
ISAVVMHTLRCLPRTGKCSHLETIALDSWDTAP
LLRREVHNLWKELMA*FRR*IVEVITPWHMCTPL
VRWYLLVMDQVTQASQLIRRP*QRTLTLAA*FL
LKTSWMFKSNTFLLEHMPTL*QLIRILVPHVLP
GKPCQK*AELASPWQKNG*Q*KEEVLNMKWLKVK
LE*YFHLLLV*LQVF*RKEELEKRLPLMWT*KW
QEIPSRS*QKRNGFLP**LRVSRMICSELFHAI
LHTKKLYQFSSCSQNVL*CMILRTGRTWWFHLQR
LCVK*VNNLCKS*RSVGHFCKNLL*IR*SRCLK
QPSSLSCFIRLKPNRITVMLKLF*E**KNCIR*
TKLTVDYQKILST*MNSPTY*TFI*IEEDSSFGI
TT*CQKRKHTCLCMKQFCKKRMNFLHHPDLYLE
SDEVAWLKMLCVN*VKLKLLTSAKY*WLNLLMK
FVLSLEGLVQSSSTVCLKR*PSQNMECSCILKWV
PACGFLPSLNLRRKDISSLECCVDSPYSI*MLL
TFLSHWLCIKNFWTKSHHWKI*KNSVLGWGRVC
KKF*MMLLMTLEMRSAYAFLYTGTKMMLT*FQMG
SPYLWTKPTRETMFLSILITFSTSL*KQFMRNF
REDFIESVRRRYLDISTLKN**QQSLEILIMTG
NSLNRIQSMSKDTKNHILLYSCFGRLSTN*PWMK
RKNSSFSLQDVIGCMQEAYRKWK*YFAVLKLSV
KEITQHQ*LVIIFSPSLSILQWKEWRKHFK*PS
TTTEDLSHPCSHSHNHL*ETQGGLSHTWILLFFL
TPK*YKRLMNSG*K*LRERLGEWGDDDDGQRVQ
NLTQD*GRRIGYRDRDLRMTWTHSLALKSLNTG
L*LVHSRTFICIRYQTTSASDWPWARPALWPMIG
SFQDIHLHKESNHTSLGLAVSQFTSVSNWL*VS
LSFT*GVTIKKPLQGT*APEDFATRALEPLALA
HSHPVECTFTFAASLPCAPINPLLHHP

Frame 1

ALEVQAARVDMGPGLRPWGGLKTG*VS*YSGNH
RAPSHQRSGACRSGTDGIRSRRQGAEAGCTSVG
APTPGSCSAGGRRAAPGLSYCRRPAGSATLCCC*
PTTGSSRAETTAGVSWAAGRAARGAARTNSGIG
NPNC*SRELREGALPGCVPQRKGLRMGSWF*RA
AGDWRIQGNKFHT*ENNDSE*YKNNTSFLWTLPL
PGIIKR*PSVFVGKEQPWAAGLGEGVPLPSQPA
EGEVPGGDPTGSGGCRRGSQLCPVSLWDFVWLG
K*QCRAAGPQWA*CPSAKQQASLSRCTEESRCGL
YQLW*CTHCGAYPGRESVHIWRQSLWTAGIQPH
S*EERSTTCGKN*WPSFADRLWKLSHPGICAHH
WSGGIFWSWTK*HKQANSSGGPDREL*H*LPDFC
*RLRGCSSQTHFCWNICQLCDNSSGY*FHTCSR
ENPARNKPN*PVHGRKMDSSEKKKY*T*NG*K*
N*NDIFISCLSDCKFFKEKRNWRNDFH*CGLRNG
KRYLQEVNKKGMDFFHDNYVSRG*SAQSSSMPF
STPRSFISFPPAPRMSCDA*F*ELEEPGGSICK
GCV*NE*TIFASPKEVLGIFARIFSESADPDA*S
SHHLSAASSD*NRTGSL*C*SSFRNDERTA*GK
QS*LSTTRKYFQHK*TLQLIKLLYR*RKTALSG
*PPDVRKESIHAYA*NNSAKKG*ISSITQIYT*S
QTKSPG*RCSASIKSS*SY*LLQSISG*IY**N
LS*VWRG*FRVLPLYV*RDDQARIWNVHVS*NG
FLHVVSCQA*T*EEKIFPLWNAVWTLLIQFKCC*
PSFPTGSV*KTSGPKAIIGRFKRTQSSVGEEFA
RSSR*CC**HWRCALHTLFYTLGPK*C*LNSKW
DLHTCGPNQQERLCF*VY*LHFQRLCKSSL*GIS
ERIL*SL*EGDT*TFLP*RTNDSNHWKY*L*LE
TV*TEFKV*ARIPKITSYYTVVLEGFPQTNLG*
KEKIPLFPYRT**AACKRHTENGNSISLS*NFQ*
KRSPNINNLS*YSLPP*VFYNGKNGGSTSSSHQ
QQQRICLTHAHTVIITSERLRVGFLTLGSFCSS
LHLNNTRD**IVVRSS*GRDWGNGEMMMMVKGCK
ISHKTEAGE*GTEIGI*G*LGHTPWH*RV*TLA
CDWSIPGPSFA*GIKPHQPLIGHGPDLHSGQ*L
VHSRTFICIRSQTTPVLDWL*ANSPQSLIGCESV
FHLHRV*PSRNLYRVLKPQKILLPGLLSHLL*P
TPTLWNVLSLLLLHCLVLQ*IHSFTT

Frame 2

HLKFRQRELTWGQGCAPGAG*RQGESLDIQEII
AHPVTSVREPVAAGPTESGAGDRAQKRDVLLLG
RRLQGAAAPEDGGQPRG*ATAGGQRGAPLSAAA
DQPQGPLVRRQQQGSAGPQGAQRGELPEPIQALE
TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQ
LGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH
SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ
RVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWG
SNSAGQLALSGRNVPVQSNKPLSVGALKNLGVV
YISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPT
PEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTT
GQVVSFGHGPSDTSKPTHPEALTENFDISCLIS
AEDFVDVQVKHIFAGTYANFVTTHQDTSSTRAPG
KTLPEISRISQSMAEKWIAVKRRSTEHEMAKSE
IRMIFSSPACLTASFLKKRGTGETTSIDVDLEM
ARDTFKKLTKKEWISSMITTCLEDDLLRALPCHS
PHQEALSVFLLLPECPVMHDSKNWKNLVVPFAK
AVCEMSKQSLQVLKKCWAFLQESSLNPLIQMLK
AAIISQLLHQTKTEQDHCNVKALLGMMKELHKVN
KANCRLPENTFNINELSNLLNFYIDRGRQLFRD
NHLMSEKKAYMLMHETILQKKDEFPPSPRFILR
VRRSRLVKDALRQLSQAEATDFCKVLVVEFINEI
CPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMG
SCMWFPAKPKPEKKRYFLFGMLCGLSLFNLNVA
NLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQ
EVLDDAADDIGDALCIRFSIHWDQNDVDLIPNG
ISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEF
QRGFYRVCEKEILRHFYPEELMTAIIGNTDYDWK
QFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDE
KKKFLFFLTGRDRLHARGIQKMEIVFRCPETFS
ERDHPTSITCHNILSLPKYSTMERMEEALQVAIN
NNRGFVSPMLTQS*SPLRDSGWAFSHLDPSVLP
YT*IIQEINE*WLEVVEGEIGGMGR***WSKGA
KSHTRLRQENRVQR*GSKDDLDTLPGTEESEHWP
VIGPFQDLHLHKVSNHISL*LAMGQTCTLANDW
FIPGHSFA*GVKPHQSWIGCEPIHLSL*LAVSQ
SFIYIGCNHQETSTGYLSPRRFCYQGS*ATCSSP
LPPCGMYFHFCCFTALCSNKSTPSPP

Copyright ©2008,2017, all rights reserved.