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Sequences

Sequence NM_020403

AGAGAGAGGAGAGGGAGAAGGAGAGAGGGGCAGAGGGGAAGGGAGAGAGGGAGAGCACGCGAGACGGAAAGGAGCGCCTCAGAGTCTCTGAAGCACGCAA GAGATAACCGATTAGGAATTTTTCGGGCAACTGTCACCCGGATAGCTGTCAGAGAATCATCATCACCGCAACTCTGACGTTTCCTACAAGAAGTTAGAGA CTTAAGCAGTATTGGCATCGGATGGAAATGGTATGCATGCTGCTGTGGAAAATATCCCTGAGCTGAAGAAGTGCAACTATGTGTTGTGTGTGCTAAATGC CCAGAAGAACCCAGACCCAGTGGGTAAGAGAGACGAAATGTGGAGAGAATGACTAACGACAAATCCGTGAATTTGTTCTCTGGAGTTGCTAATTTGCCAG CCCGAAGCAACACATTTTACAAGGAGGAAACATTTTGCTGCTTCTGATTTCTCCCCAAACTGGTGCTACCAGATGCATGGCTTTCTATGTGTTGGAACAA ATCATTCCTAACTGCAGCATACTGGGAAAGGGGAAAGGTTGAGGCAACTAACCGGCTGTCTCCAAATAAGTGATGAGATATAATGCATCCTCCAGTCCAT GCACGCTTCCTCTTGCAATTTGTGCATCATTCCTCAGTGGAAACCTTTAAACCCTAAAATCCAGGAAAAGAAAATAAATACATTATCATGGACCTGAGGG ATTTTTACCTGTTGGCTGCTCTGATTGCCTGTTTAAGGCTGGATTCCGCAATAGCTCAAGAACTTATTTACACTATTAGAGAGGAATTGCCTGAAAATGT GCCCATAGGAAACATACCAAAGGATCTGAACATTTCTCACATCAATGCTGCCACAGGGACCAGCGCCAGCCTTGTCTACAGACTGGTTTCTAAAGCTGGG GATGCCCCTTTGGTGAAAGTTTCCAGCAGCACTGGGGAAATTTTCACAACCTCCAACAGAATAGACAGAGAAAAACTCTGTGCTGGCGCCTCATATGCTG AGGAGAATGAGTGTTTCTTTGAACTTGAGGTGGTGATCCTCCCCAATGATTTCTTCAGGCTGATCAAAATAAAAATAATTGTCAAGGATACCAATGATAA TGCCCCCATGTTTCCATCTCCTGTCATCAATATTTCCATTCCAGAAAACACTTTGATCAACAGCCGCTTTCCAATTCCATCAGCAACAGATCCTGACACA GGCTTCAATGGTGTACAGCATTATGAATTGTTAAATGGGCAGAGTGTTTTTGGACTGGATATCGTGGAAACTCCAGAGGGAGAGAAGTGGCCACAACTGA TTGTTCAGCAAAACTTGGATAGAGAACAGAAAGATACCTATGTGATGAAAATCAAAGTAGAGGATGGAGGCACTCCACAGAAATCCAGTACGGCCATACT GCAGGTCACAGTAAGTGATGTAAATGACAACAGGCCAGTGTTTAAAGAGGGTCAAGTGGAGGTGCATATTCCAGAGAATGCTCCCGTAGGTACCTCTGTA ATTCAGCTCCATGCCACTGATGCAGATATAGGCAGTAATGCTGAAATCCGGTACATTTTTGGTGCCCAGGTCGCCCCTGCAACCAAAAGACTCTTTGCTT TAAATAATACTACTGGGCTGATTACAGTTCAGAGGTCCTTAGATAGAGAGGAGACAGCCATTCACAAAGTGACAGTGCTGGCTAGTGACGGCAGCTCCAC TCCTGCTCGAGCAACGGTTACCATCAATGTCACCGATGTAAATGATAACCCTCCTAATATAGACCTCAGGTACATTATAAGTCCCATCAATGGCACCGTG TATTTATCTGAGAAAGATCCTGTCAATACAAAGATTGCCCTAATTACAGTTTCAGATAAGGACACAGATGTGAATGGCAAAGTGATCTGTTTTATTGAAA GAGAGGTCCCATTTCATTTGAAGGCGGTATATGACAACCAATATTTGTTAGAGACCTCTTCTTTGTTGGACTATGAGGGCACCAAAGAATTCAGCTTTAA AATTGTTGCCTCTGATTCTGGGAAGCCCAGTTTAAATCAGACTGCCCTGGTAAGGGTTAAGCTTGAGGATGAAAATGACAACCCACCAATTTTCAACCAG CCTGTAATTGAGCTGTCAGTTTCTGAAAACAACCGACGTGGGTTATACTTAACAACTATTAGTGCCACAGATGAAGACAGTGGGAAAAATGCAGACATTG TTTATCAGCTTGGACCGAATGCCTCCTTCTTTGATCTGGACCGAAAAACAGGAGTTTTGACAGCCTCCAGAGTATTTGACAGAGAAGAACAAGAACGATT CATTTTTACAGTAACTGCCAGGGACAATGGGACCCCTCCCCTCCAAAGCCAAGCGGCTGTGATTGTTACTGTTCTGGATGAGAATGACAATAGCCCCAAG TTTACTCATAATCATTTTCAATTTTTTGTGTCTGAGAATCTGCCAAAGTATAGTACTGTGGGGGTAATCACAGTGACAGATGCAGATGCTGGAGAGAATA AAGCTGTGACTCTTTCCATTCTAAATGACAATGATAATTTTGTGTTGGATCCCTATTCTGGAGTCATAAAGTCAAATGTCTCATTTGATAGAGAGCAGCA GAGTTCCTACACTTTTGATGTCAAAGCCACTGATGGAGGACAACCACCTCGTTCCTCTACTGCAAAAGTAACTATCAACGTCATGGATGTCAATGACAAC AGCCCAGTTGTCATTTCTCCACCGTCTAATACTTCCTTTAAGTTGGTGCCCCTCTCAGCCATTCCTGGCTCCGTGGTAGCAGAAGTTTTTGCAGTGGATG TTGACACTGGAATGAACGCTGAACTAAAGTATACTATAGTGAGTGGAAACAATAAAGGCTTATTCCGGATTGATCCAGTAACAGGTAACATTACTCTGGA AGAAAAACCAGCACCTACTGATGTGGGATTGCATCGTTTGGTGGTCAACATAAGTGACCTGGGGTACCCTAAGTCTTTGCACACGCTTGTGCTTGTATTC CTTTATGTTAACGACACTGCTGGAAATGCCTCCTATATCTATGACTTGATCCGCAGGACTATGGAGACCCCGTTGGACAGGAACATAGGGGATAGTAGCC AACCCTATCAAAATGAGGACTATCTAACCATCATGATTGCCATCATCGCCGGTGCCATGGTGGTCATTGTTGTGATCTTCGTCACCGTTCTGGTGCGCTG TCGCCATGCATCAAGGTTCAAAGCAGCTCAGAGGAGCAAGCAAGGTGCCGAATGGATGTCCCCAAACCAGGAGAACAAGCAAAACAAGAAAAAGAAAAGA AAGAAAAGGAAGTCTCCCAAAAGCTCTCTTTTGAACTTTGTTACTATCGAAGAGTCCAAACCCGATGATGCAGTTCATGAACCTATCAATGGGACAATAA GCCTGCCGGCTGAACTGGAGGAGCAAAGTATAGGAAGATTTGACTGGGGCCCGGCACCTCCAACAACATTCAAGCCTAACAGTCCTGACCTGGCCAAGCA CTACAAATCTGCTTCTCCACAGCCTGCTTTTCATCTCAAACCAGACACTCCAGTTTCCGTGAAAAAGCACCACGTGATTCAGGAACTCCCTTTGGACAAC ACCTTTGTTGGGGGTTGTGACACCCTTTCTAAACGCTCTTCCACTAGTTCAGATCACTTCAGTGCCTCAGAGTGCAGTTCCCAAGGAGGCTTCAAGACAA AGGGCCCCTTACACACCAGACAGTCGCAGCGCCGTGTTACGTTTCATCTCCCTGATGGCTCCCAGGAAAGCTGCAGTGACAGTGGTCTAGGAGACCATGA GCCGGTGGGTAGTGGAACCCTGATCTCACACCCTCTTCCTCTGGTTCAGCCACAGGACGAATTCTATGACCAGGCCTCTCCGGACAAGAGGACTGAAGCA GATGGCAACTCTGATCCCAACTCTGATGGGCCTTTGGGTCCCCGAGGATTAGCTGAAGCTACAGAGATGTGCACTCAAGAGTGCTTGGTTTTGGGTCACT CTGATAATTGCTGGATGCCTCCTGGCTTGGGTCCATATCAACACCCCAAATCTCCTCTCTCAACCTTTGCACCCCAGAAAGAATGGGTGAAGAAGGACAA GCTTGTGAATGGGCACACCCTGACCAGAGCCTGGAAAGAAGACAGCAACAGGAACCAGTTCAATGACCGTAAGCAGTATGGCTCCAATGAAGGCCATTTC AACAATGGCAGCCACATGACAGACATTCCTCTGGCAAATCTGAAGTCTTATAAGCAAGCAGGAGGTGCTACTGAGAGTCCTAAGGAGCACCAACTCTAAG AAAAGGCTATATGGGACCTAATAACTTTAAATAGACATGCTAATACCGTGTGCGTCAGAGCTTTATGTATTCAATAGATCTCTACAACTATGCCCCTTCT AGCAGGGATACCTATAACTTTGTGTTAGCACCATGGAGAATACAATGTTTTTGCAACATATGAGAGAAGATAGTTCTAGCCATGCAATTTTGTTTACTAG AATTGATTACACTCTCCAGAGATCTCTCCATTGTGCAAATTTTTTTTATTATTGCATTTTATTTTGACCCTGGACTGCTGCTATGAACAATAGAATATGC ATTTGGAAAGTAAGAAAGTTTCATGGATTAGAGTGACTGAAAAACATATCCAGTTAGAAAATTGTGCTTTTTTTTTTTTTTTTTTTTTTTTTTGTCATTG ATTTGTGCTGGGACTGCTATACTTGACATTATACTGCAAACAAAACTTAAAGAGATAAGCATTAAACCTATTGTGCTGTTAACAACGTTAGTGGACACTT GTAAGTCAATCAGTGTTAAAGTATTTGTAAATAGAAGCAAGCTATTATTAACAACTTTTGTGTACTTATAATGTTCACCTAAAAATGTTGTAGCATAATT CTGTGTTTTATGGTTGCTTCTGTCCTTCTTTTTATTTACCTCTTTGTTGTTATTTTTGTTGTTTCTTTCAGTGAGGTGTTTCTGTGTTAGTAGTCTGTCT TGACACACATTGTTCAAACAATCTCAAGCACTTGTGTTTAAAAAAGGTTCTGAAATCTTGCTTCTCATATGATAGCTTATGATGCCGGAATTCTGTAAAC AATAAAGATGAAAGAAAAAATGAAAACTTTATACAAAAAAGGACTTCTGCAAAAGCTTGGAAATTCAGAACCTATTTTTTATCATCTTATTTTCAAAGTA GGCAAAAGCAAAATCACTTAATTAGTACCATTAAGTGAGAGAGTAATGGAAAACTGTTATCCATCAAAAGTGATATAATATCCTGTACTTGTCACTCATG TAAAACTAATGTATCAAAATTAGCATATATGGAAGAAAAATCACTATTCAAAAATAGTTTCAATTGGGCAAATGTGTGTCTACAACTTTGTTGAAATGGC AGAGTCTGTGTTGATCCTCATATACAATAATGTTGTTGTAACACAAGTGTTATTAGACCATAGCCACAAAATATTTAATGTGTTGTGCCTTCATGATGTA ACAGAACATTCTCCAGGTAGGGTAGTTGGGGGAAATAAAGGGATAAATCTCTAATTATTGCTGTTTAACTGTTTGTTATCATAGTTGGTCAATGCCTGGC AGGTACCAGCATATTGTCACTTAGGTCAAACCAATAAAGTGACAACTAATGTTAATAAGATCTCAGTTGCACGTGCAAACAAATCCAAATTCGAACATTC TTAGGAGGTTTTTGTTAAGGCATGACAGATGATTTAAACAAATAAATAGCATGCAACAAAATGTCTTTATTGAAAGAAGTGGAAGTTATCTTAATGCCAC GGTTCACCATCAATTTAAAAGTAAAAAAAACAAAAAAAAAACAAAAAATTTAAAAAAAAGGTTTGCTAATCTGATAGTTAATTTGTTCTTACCAAAAAAT AAAATTACTTTGTAAATAGCAGTTCACATTTTTCCACAGTATAATGGAAAATAATGGGTAGGGGTGCATTGCTTATTGAAGTACATTTTTGTCGGTTTGT GAGGGGTGTTTGATGACTTTGACAGAATAAATATCTAAACAATTATCCTTGTTACTGCTTTGCCAGTTCTACGTTATTTACAATTATTCAGCTCTTGCAA TAAATGTTCTGAATTCCTGA

refseq_PCDH9.F1 (forward primer)
refseq_PCDH9.R1 (reverse primer)
Single exon skipping

Frame 0

RERRGRRREGQRGRERGRARETERSASESLKHA RDNRLGIFRATVTRIAVRESSSPQL*RFLQEVRD LSSIGIGWKWYACCCGKYP*AEEVQLCVVCAKC PEEPRPSG*ERRNVERMTNDKSVNLFSGVANLP ARSNTFYKEETFCCF*FLPKLVLPDAWLSMCWNK SFLTAAYWERGKVEATNRLSPNK**DIMHPPVH ARFLLQFVHHSSVETFKP*NPGKENKYIIMDLR DFYLLAALIACLRLDSAIAQELIYTIREELPENV PIGNIPKDLNISHINAATGTSASLVYRLVSKAG DAPLVKVSSSTGEIFTTSNRIDREKLCAGASYA EENECFFELEVVILPNDFFRLIKIKIIVKDTNDN APMFPSPVINISIPENTLINSRFPIPSATDPDT GFNGVQHYELLNGQSVFGLDIVETPEGEKWPQL IVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAIL QVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSV IQLHATDADIGSNAEIRYIFGAQVAPATKRLFA LNNTTGLITVQRSLDREETAIHKVTVLASDGSST PARATVTINVTDVNDNPPNIDLRYIISPINGTV YLSEKDPVNTKIALITVSDKDTDVNGKVICFIE REVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFK IVASDSGKPSLNQTALVRVKLEDENDNPPIFNQ PVIELSVSENNRRGLYLTTISATDEDSGKNADI VYQLGPNASFFDLDRKTGVLTASRVFDREEQERF IFTVTARDNGTPPLQSQAAVIVTVLDENDNSPK FTHNHFQFFVSENLPKYSTVGVITVTDADAGEN KAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDN SPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVD VDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLE EKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVF LYVNDTAGNASYIYDLIRRTMETPLDRNIGDSS QPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRC RHASRFKAAQRSKQGAEWMSPNQENKQNKKKKR KKRKSPKSSLLNFVTIEESKPDDAVHEPINGTI SLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKH YKSASPQPAFHLKPDTPVSVKKHHVIQELPLDN TFVGGCDTLSKRSSTSSDHFSASECSSQGGFKT KGPLHTRQSQRRVTFHLPDGSQESCSDSGLGDHE PVGSGTLISHPLPLVQPQDEFYDQASPDKRTEA DGNSDPNSDGPLGPRGLAEATEMCTQECLVLGH SDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDK LVNGHTLTRAWKEDSNRNQFNDRKQYGSNEGHF NNGSHMTDIPLANLKSYKQAGGATESPKEHQL* EKAIWDLITLNRHANTVCVRALCIQ*ISTTMPLL AGIPITLC*HHGEYNVFATYERR*F*PCNFVY* N*LHSPEISPLCKFFLLLHFILTLDCCYEQ*NM HLESKKVSWIRVTEKHIQLENCAFFFFFFFFCH* FVLGLLYLTLYCKQNLKR*ALNLLCC*QR*WTL VSQSVLKYL*IEASYY*QLLCTYNVHLKML*HN SVFYGCFCPSFYLPLCCYFCCFFQ*GVSVLVVCL DTHCSNNLKHLCLKKVLKSCFSYDSL*CRNSVN NKDERKNENFIQKRTSAKAWKFRTYFLSSYFQS RQKQNHLISTIK*ESNGKLLSIKSDIISCTCHSC KTNVSKLAYMEEKSLFKNSFNWANVCLQLC*NG RVCVDPHIQ*CCCNTSVIRP*PQNI*CVVPS*C NRTFSR*GSWGK*RDKSLIIAV*LFVIIVGQCLA GTSILSLRSNQ*SDN*C**DLSCTCKQIQIRTF LGGFC*GMTDDLNK*IACNKMSLLKEVEVILMP RFTINLKVKKTKKKQKI*KKGLLI**LICSYQKI KLLCK*QFTFFHSIMENNG*GCIAY*STFLSVC EGCLMTLTE*ISKQLSLLLLCQFYVIYNYSALA INVLNS*

Frame 1

ERGEGEGERGRGEGREGEHARRKGAPQSL*STQ EITD*EFFGQLSPG*LSENHHHRNSDVSYKKLE T*AVLASDGNGMHAAVENIPELKKCNYVLCVLNA QKNPDPVGKRDEMWRE*LTTNP*ICSLELLICQ PEATHFTRRKHFAASDFSPNWCYQMHGFLCVGT NHS*LQHTGKGERLRQLTGCLQISDEI*CILQSM HASSCNLCIIPQWKPLNPKIQEKKINTLSWT*G IFTCWLL*LPV*GWIPQ*LKNLFTLLERNCLKM CP*ETYQRI*TFLTSMLPQGPAPALSTDWFLKLG MPLW*KFPAALGKFSQPPTE*TEKNSVLAPHML RRMSVSLNLRW*SSPMISSG*SK*K*LSRIPMI MPPCFHLLSSIFPFQKTL*STAAFQFHQQQILTQ ASMVYSIMNC*MGRVFLDWISWKLQRERSGHN* LFSKTWIENRKIPM**KSK*RMEALHRNPVRPY CRSQ*VM*MTTGQCLKRVKWRCIFQRMLP*VPL* FSSMPLMQI*AVMLKSGTFLVPRSPLQPKDSLL *IILLG*LQFRGP*IERRQPFTK*QCWLVTAAP LLLEQRLPSMSPM*MITLLI*TSGTL*VPSMAPC IYLRKILSIQRLP*LQFQIRTQM*MAK*SVLLK ERSHFI*RRYMTTNIC*RPLLCWTMRAPKNSAL KLLPLILGSPV*IRLPW*GLSLRMKMTTHQFSTS L*LSCQFLKTTDVGYT*QLLVPQMKTVGKMQTL FISLDRMPPSLIWTEKQEF*QPPEYLTEKNKND SFLQ*LPGTMGPLPSKAKRL*LLLFWMRMTIAPS LLIIIFNFLCLRICQSIVLWG*SQ*QMQMLERI KL*LFPF*MTMIILCWIPILES*SQMSHLIESS RVPTLLMSKPLMEDNHLVPLLQK*LSTSWMSMTT AQLSFLHRLILPLSWCPSQPFLAPW*QKFLQWM LTLE*TLN*SIL**VETIKAYSGLIQ*QVTLLW KKNQHLLMWDCIVWWST*VTWGTLSLCTRLCLYS FMLTTLLEMPPISMT*SAGLWRPRWTGT*GIVA NPIKMRTI*PS*LPSSPVPWWSLL*SSSPFWCA VAMHQGSKQLRGASKVPNGCPQTRRTSKTRKRKE RKGSLPKALF*TLLLSKSPNPMMQFMNLSMGQ* ACRLNWRSKV*EDLTGARHLQQHSSLTVLTWPS TTNLLLHSLLFISNQTLQFP*KSTT*FRNSLWTT PLLGVVTPFLNALPLVQITSVPQSAVPKEASRQ RAPYTPDSRSAVLRFISLMAPRKAAVTVV*ETM SRWVVEP*SHTLFLWFSHRTNSMTRPLRTRGLKQ MATLIPTLMGLWVPED*LKLQRCALKSAWFWVT LIIAGCLLAWVHINTPNLLSQPLHPRKNG*RRT SL*MGTP*PEPGKKTATGTSSMTVSSMAPMKAIS TMAAT*QTFLWQI*SLISKQEVLLRVLRSTNSK KRLYGT**L*IDMLIPCASELYVFNRSLQLCPF *QGYL*LCVSTMENTMFLQHMREDSSSHAILFTR IDYTLQRSLHCANFFYYCILF*PWTAAMNNRIC IWKVRKFHGLE*LKNISS*KIVLFFFFFFFFVI DLCWDCYT*HYTANKT*RDKH*TYCAVNNVSGHL *VNQC*SICK*KQAIINNFCVLIMFT*KCCSII LCFMVASVLLFIYLFVVIFVVSFSEVFLC**SV LTHIVQTISSTCV*KRF*NLASHMIAYDAGIL*T IKMKEKMKTLYKKGLLQKLGNSEPIFYHLIFKV GKSKIT*LVPLSERVMENCYPSKVI*YPVLVTH VKLMYQN*HIWKKNHYSKIVSIGQMCVYNFVEMA ESVLILIYNNVVVTQVLLDHSHKIFNVLCLHDV TEHSPGRVVGGNKGINL*LLLFNCLLS*LVNAW QVPAYCHLGQTNKVTTNVNKISVARANKSKFEHS *EVFVKA*QMI*TNK*HATKCLY*KKWKLS*CH GSPSI*K*KKQKKNKKFKKKVC*SDS*FVLTKK *NYFVNSSSHFSTV*WKIMGRGALLIEVHFCRFV RGV**L*QNKYLNNYPCYCFASSTLFTIIQLLQ *MF*IP

Frame 2

REEREKERGAEGKGERESTRDGKERLRVSEARK R*PIRNFSGNCHPDSCQRIIITATLTFPTRS*R LKQYWHRMEMVCMLLWKISLS*RSATMCCVC*M PRRTQTQWVRETKCGEND*RQIREFVLWSC*FAS PKQHILQGGNILLLLISPQTGATRCMAFYVLEQ IIPNCSILGKGKG*GN*PAVSK*VMRYNASSSP CTLPLAICASFLSGNL*TLKSRKRK*IHYHGPEG FLPVGCSDCLFKAGFRNSSRTYLHY*RGIA*KC AHRKHTKGSEHFSHQCCHRDQRQPCLQTGF*SW GCPFGESFQQHWGNFHNLQQNRQRKTLCWRLIC* GE*VFL*T*GGDPPQ*FLQADQNKNNCQGYQ** CPHVSISCHQYFHSRKHFDQQPLSNSISNRS*H RLQWCTAL*IVKWAECFWTGYRGNSRGREVATTD CSAKLG*RTERYLCDENQSRGWRHSTEIQYGHT AGHSK*CK*QQASV*RGSSGGAYSRECSRRYLC NSAPCH*CRYRQ*C*NPVHFWCPGRPCNQKTLCF K*YYWADYSSEVLR*RGDSHSQSDSAG**RQLH SCSSNGYHQCHRCK**PS*YRPQVHYKSHQWHR VFI*ERSCQYKDCPNYSFR*GHRCEWQSDLFY*K RGPISFEGGI*QPIFVRDLFFVGL*GHQRIQL* NCCL*FWEAQFKSDCPGKG*A*G*K*QPTNFQP ACN*AVSF*KQPTWVILNNY*CHR*RQWEKCRHC LSAWTECLLL*SGPKNRSFDSLQSI*QRRTRTI HFYSNCQGQWDPSPPKPSGCDCYCSG*E*Q*PQ VYS*SFSIFCV*ESAKV*YCGGNHSDRCRCWRE* SCDSFHSK*Q**FCVGSLFWSHKVKCLI**RAA EFLHF*CQSH*WRTTTSFLYCKSNYQRHGCQ*Q QPSCHFSTV*YFL*VGAPLSHSWLRGSRSFCSGC *HWNER*TKVYYSEWKQ*RLIPD*SSNR*HYSG RKTSTY*CGIASFGGQHK*PGVP*VFAHACACI PLC*RHCWKCLLYL*LDPQDYGDPVGQEHRG**P TLSK*GLSNHHDCHHRRCHGGHCCDLRHRSGAL SPCIKVQSSSEEQARCRMDVPKPGEQAKQEKEK KEKEVSQKLSFELCYYRRVQTR*CSS*TYQWDNK PAG*TGGAKYRKI*LGPGTSNNIQA*QS*PGQA LQICFSTACFSSQTRHSSFREKAPRDSGTPFGQ HLCWGL*HPF*TLFH*FRSLQCLRVQFPRRLQDK GPLTHQTVAAPCYVSSP*WLPGKLQ*QWSRRP* AGG*WNPDLTPSSSGSATGRIL*PGLSGQED*S RWQL*SQL*WAFGSPRIS*SYRDVHSRVLGFGSL **LLDASWLGSISTPQISSLNLCTPERMGEEGQ ACEWAHPDQSLERRQQQEPVQ*P*AVWLQ*RPF QQWQPHDRHSSGKSEVL*ASRRCY*ES*GAPTLR KGYMGPNNFK*TC*YRVRQSFMYSIDLYNYAPS SRDTYNFVLAPWRIQCFCNI*EKIVLAMQFCLL ELITLSRDLSIVQIFFIIAFYFDPGLLL*TIEYA FGK*ESFMD*SD*KTYPVRKLCFFFFFFFFLSL ICAGTAILDIILQTKLKEISIKPIVLLTTLVDT CKSISVKVFVNRSKLLLTTFVYL*CSPKNVVA*F CVLWLLLSFFLFTSLLLFLLFLSVRCFCVSSLS *HTLFKQSQALVFKKGSEILLLI**LMMPEFCK Q*R*KKK*KLYTKKDFCKSLEIQNLFFIILFSK* AKAKSLN*YH*VRE*WKTVIHQK*YNILYLSLM *N*CIKISIYGRKITIQK*FQLGKCVSTTLLKW QSLC*SSYTIMLL*HKCY*TIATKYLMCCAFMM* QNILQVG*LGEIKG*ISNYCCLTVCYHSWSMPG RYQHIVT*VKPIK*QLMLIRSQLHVQTNPNSNI LRRFLLRHDR*FKQINSMQQNVFIERSGSYLNAT VHHQFKSKKNKKKTKNLKKRFANLIVNLFLPKN KITL*IAVHIFPQYNGK*WVGVHCLLKYIFVGL *GVFDDFDRINI*TIILVTALPVLRYLQLFSSCN KCSEFL

Sequence NM_203487

AGAGAGAGGAGAGGGAGAAGGAGAGAGGGGCAGAGGGGAAGGGAGAGAGGGAGAGCACGCGAGACGGAAAGGAGCGCCTCAGAGTCTCTGAAGCACGCAA GAGATAACCGATTAGGAATTTTTCGGGCAACTGTCACCCGGATAGCTGTCAGAGAATCATCATCACCGCAACTCTGACGTTTCCTACAAGAAGTTAGAGA CTTAAGCAGTATTGGCATCGGATGGAAATGGTATGCATGCTGCTGTGGAAAATATCCCTGAGCTGAAGAAGTGCAACTATGTGTTGTGTGTGCTAAATGC CCAGAAGAACCCAGACCCAGTGGGTAAGAGAGACGAAATGTGGAGAGAATGACTAACGACAAATCCGTGAATTTGTTCTCTGGAGTTGCTAATTTGCCAG CCCGAAGCAACACATTTTACAAGGAGGAAACATTTTGCTGCTTCTGATTTCTCCCCAAACTGGTGCTACCAGATGCATGGCTTTCTATGTGTTGGAACAA ATCATTCCTAACTGCAGCATACTGGGAAAGGGGAAAGGTTGAGGCAACTAACCGGCTGTCTCCAAATAAGTGATGAGATATAATGCATCCTCCAGTCCAT GCACGCTTCCTCTTGCAATTTGTGCATCATTCCTCAGTGGAAACCTTTAAACCCTAAAATCCAGGAAAAGAAAATAAATACATTATCATGGACCTGAGGG ATTTTTACCTGTTGGCTGCTCTGATTGCCTGTTTAAGGCTGGATTCCGCAATAGCTCAAGAACTTATTTACACTATTAGAGAGGAATTGCCTGAAAATGT GCCCATAGGAAACATACCAAAGGATCTGAACATTTCTCACATCAATGCTGCCACAGGGACCAGCGCCAGCCTTGTCTACAGACTGGTTTCTAAAGCTGGG GATGCCCCTTTGGTGAAAGTTTCCAGCAGCACTGGGGAAATTTTCACAACCTCCAACAGAATAGACAGAGAAAAACTCTGTGCTGGCGCCTCATATGCTG AGGAGAATGAGTGTTTCTTTGAACTTGAGGTGGTGATCCTCCCCAATGATTTCTTCAGGCTGATCAAAATAAAAATAATTGTCAAGGATACCAATGATAA TGCCCCCATGTTTCCATCTCCTGTCATCAATATTTCCATTCCAGAAAACACTTTGATCAACAGCCGCTTTCCAATTCCATCAGCAACAGATCCTGACACA GGCTTCAATGGTGTACAGCATTATGAATTGTTAAATGGGCAGAGTGTTTTTGGACTGGATATCGTGGAAACTCCAGAGGGAGAGAAGTGGCCACAACTGA TTGTTCAGCAAAACTTGGATAGAGAACAGAAAGATACCTATGTGATGAAAATCAAAGTAGAGGATGGAGGCACTCCACAGAAATCCAGTACGGCCATACT GCAGGTCACAGTAAGTGATGTAAATGACAACAGGCCAGTGTTTAAAGAGGGTCAAGTGGAGGTGCATATTCCAGAGAATGCTCCCGTAGGTACCTCTGTA ATTCAGCTCCATGCCACTGATGCAGATATAGGCAGTAATGCTGAAATCCGGTACATTTTTGGTGCCCAGGTCGCCCCTGCAACCAAAAGACTCTTTGCTT TAAATAATACTACTGGGCTGATTACAGTTCAGAGGTCCTTAGATAGAGAGGAGACAGCCATTCACAAAGTGACAGTGCTGGCTAGTGACGGCAGCTCCAC TCCTGCTCGAGCAACGGTTACCATCAATGTCACCGATGTAAATGATAACCCTCCTAATATAGACCTCAGGTACATTATAAGTCCCATCAATGGCACCGTG TATTTATCTGAGAAAGATCCTGTCAATACAAAGATTGCCCTAATTACAGTTTCAGATAAGGACACAGATGTGAATGGCAAAGTGATCTGTTTTATTGAAA GAGAGGTCCCATTTCATTTGAAGGCGGTATATGACAACCAATATTTGTTAGAGACCTCTTCTTTGTTGGACTATGAGGGCACCAAAGAATTCAGCTTTAA AATTGTTGCCTCTGATTCTGGGAAGCCCAGTTTAAATCAGACTGCCCTGGTAAGGGTTAAGCTTGAGGATGAAAATGACAACCCACCAATTTTCAACCAG CCTGTAATTGAGCTGTCAGTTTCTGAAAACAACCGACGTGGGTTATACTTAACAACTATTAGTGCCACAGATGAAGACAGTGGGAAAAATGCAGACATTG TTTATCAGCTTGGACCGAATGCCTCCTTCTTTGATCTGGACCGAAAAACAGGAGTTTTGACAGCCTCCAGAGTATTTGACAGAGAAGAACAAGAACGATT CATTTTTACAGTAACTGCCAGGGACAATGGGACCCCTCCCCTCCAAAGCCAAGCGGCTGTGATTGTTACTGTTCTGGATGAGAATGACAATAGCCCCAAG TTTACTCATAATCATTTTCAATTTTTTGTGTCTGAGAATCTGCCAAAGTATAGTACTGTGGGGGTAATCACAGTGACAGATGCAGATGCTGGAGAGAATA AAGCTGTGACTCTTTCCATTCTAAATGACAATGATAATTTTGTGTTGGATCCCTATTCTGGAGTCATAAAGTCAAATGTCTCATTTGATAGAGAGCAGCA GAGTTCCTACACTTTTGATGTCAAAGCCACTGATGGAGGACAACCACCTCGTTCCTCTACTGCAAAAGTAACTATCAACGTCATGGATGTCAATGACAAC AGCCCAGTTGTCATTTCTCCACCGTCTAATACTTCCTTTAAGTTGGTGCCCCTCTCAGCCATTCCTGGCTCCGTGGTAGCAGAAGTTTTTGCAGTGGATG TTGACACTGGAATGAACGCTGAACTAAAGTATACTATAGTGAGTGGAAACAATAAAGGCTTATTCCGGATTGATCCAGTAACAGGTAACATTACTCTGGA AGAAAAACCAGCACCTACTGATGTGGGATTGCATCGTTTGGTGGTCAACATAAGTGACCTGGGGTACCCTAAGTCTTTGCACACGCTTGTGCTTGTATTC CTTTATGTTAACGACACTGCTGGAAATGCCTCCTATATCTATGACTTGATCCGCAGGACTATGGAGACCCCGTTGGACAGGAACATAGGGGATAGTAGCC AACCCTATCAAAATGAGGACTATCTAACCATCATGATTGCCATCATCGCCGGTGCCATGGTGGTCATTGTTGTGATCTTCGTCACCGTTCTGGTGCGCTG TCGCCATGCATCAAGGTTCAAAGCAGCTCAGAGGAGCAAGCAAGGTGCCGAATGGATGTCCCCAAACCAGGAGAACAAGCAAAACAAGAAAAAGAAAAGA AAGAAAAGGAAGTCTCCCAAAAGCTCTCTTTTGAACTTTGTTACTATCGAAGAGTCCAAACCCGATGATGCAGTTCATGAACCTATCAATGGGACAATAA GCCTGCCGGCTGAACTGGAGGAGCAAAGTATAGGAAGATTTGACTGGGGCCCGGCACCTCCAACAACATTCAAGCCTAACAGTCCTGACCTGGCCAAGCA CTACAAATCTGCTTCTCCACAGCCTGCTTTTCATCTCAAACCAGACACTCCAGTTTCCGTGAAAAAGCACCACGTGATTCAGGAACTCCCTTTGGACAAC ACCTTTGTTGGGGGTTGTGACACCCTTTCTAAACGCTCTTCCACTAGTTCAGATCACTTCAGTGCCTCAGAGTGCAGTTCCCAAGGAGGCTTCAAGACAA AGGGCCCCTTACACACCAGACAGTGTAACTCACACAGCAAAAGTGACAATATTCCTGTCACTCCTCAGAAATGTCCCAGCTCCACGGGTTTCCACATTCA GGAGAATGAAGAAAGCCATTACGAGTCGCAGCGCCGTGTTACGTTTCATCTCCCTGATGGCTCCCAGGAAAGCTGCAGTGACAGTGGTCTAGGAGACCAT GAGCCGGTGGGTAGTGGAACCCTGATCTCACACCCTCTTCCTCTGGTTCAGCCACAGGACGAATTCTATGACCAGGCCTCTCCGGACAAGAGGACTGAAG CAGATGGCAACTCTGATCCCAACTCTGATGGGCCTTTGGGTCCCCGAGGATTAGCTGAAGCTACAGAGATGTGCACTCAAGAGTGCTTGGTTTTGGGTCA CTCTGATAATTGCTGGATGCCTCCTGGCTTGGGTCCATATCAACACCCCAAATCTCCTCTCTCAACCTTTGCACCCCAGAAAGAATGGGTGAAGAAGGAC AAGCTTGTGAATGGGCACACCCTGACCAGAGCCTGGAAAGAAGACAGCAACAGGAACCAGTTCAATGACCGTAAGCAGTATGGCTCCAATGAAGGCCATT TCAACAATGGCAGCCACATGACAGACATTCCTCTGGCAAATCTGAAGTCTTATAAGCAAGCAGGAGGTGCTACTGAGAGTCCTAAGGAGCACCAACTCTA AGAAAAGGCTATATGGGACCTAATAACTTTAAATAGACATGCTAATACCGTGTGCGTCAGAGCTTTATGTATTCAATAGATCTCTACAACTATGCCCCTT CTAGCAGGGATACCTATAACTTTGTGTTAGCACCATGGAGAATACAATGTTTTTGCAACATATGAGAGAAGATAGTTCTAGCCATGCAATTTTGTTTACT AGAATTGATTACACTCTCCAGAGATCTCTCCATTGTGCAAATTTTTTTTATTATTGCATTTTATTTTGACCCTGGACTGCTGCTATGAACAATAGAATAT GCATTTGGAAAGTAAGAAAGTTTCATGGATTAGAGTGACTGAAAAACATATCCAGTTAGAAAATTGTGCTTTTTTTTTTTTTTTTTTTTTTTTTTGTCAT TGATTTGTGCTGGGACTGCTATACTTGACATTATACTGCAAACAAAACTTAAAGAGATAAGCATTAAACCTATTGTGCTGTTAACAACGTTAGTGGACAC TTGTAAGTCAATCAGTGTTAAAGTATTTGTAAATAGAAGCAAGCTATTATTAACAACTTTTGTGTACTTATAATGTTCACCTAAAAATGTTGTAGCATAA TTCTGTGTTTTATGGTTGCTTCTGTCCTTCTTTTTATTTACCTCTTTGTTGTTATTTTTGTTGTTTCTTTCAGTGAGGTGTTTCTGTGTTAGTAGTCTGT CTTGACACACATTGTTCAAACAATCTCAAGCACTTGTGTTTAAAAAAGGTTCTGAAATCTTGCTTCTCATATGATAGCTTATGATGCCGGAATTCTGTAA ACAATAAAGATGAAAGAAAAAATGAAAACTTTATACAAAAAAGGACTTCTGCAAAAGCTTGGAAATTCAGAACCTATTTTTTATCATCTTATTTTCAAAG TAGGCAAAAGCAAAATCACTTAATTAGTACCATTAAGTGAGAGAGTAATGGAAAACTGTTATCCATCAAAAGTGATATAATATCCTGTACTTGTCACTCA TGTAAAACTAATGTATCAAAATTAGCATATATGGAAGAAAAATCACTATTCAAAAATAGTTTCAATTGGGCAAATGTGTGTCTACAACTTTGTTGAAATG GCAGAGTCTGTGTTGATCCTCATATACAATAATGTTGTTGTAACACAAGTGTTATTAGACCATAGCCACAAAATATTTAATGTGTTGTGCCTTCATGATG TAACAGAACATTCTCCAGGTAGGGTAGTTGGGGGAAATAAAGGGATAAATCTCTAATTATTGCTGTTTAACTGTTTGTTATCATAGTTGGTCAATGCCTG GCAGGTACCAGCATATTGTCACTTAGGTCAAACCAATAAAGTGACAACTAATGTTAATAAGATCTCAGTTGCACGTGCAAACAAATCCAAATTCGAACAT TCTTAGGAGGTTTTTGTTAAGGCATGACAGATGATTTAAACAAATAAATAGCATGCAACAAAATGTCTTTATTGAAAGAAGTGGAAGTTATCTTAATGCC ACGGTTCACCATCAATTTAAAAGTAAAAAAAACAAAAAAAAAACAAAAAATTTAAAAAAAAGGTTTGCTAATCTGATAGTTAATTTGTTCTTACCAAAAA ATAAAATTACTTTGTAAATAGCAGTTCACATTTTTCCACAGTATAATGGAAAATAATGGGTAGGGGTGCATTGCTTATTGAAGTACATTTTTGTCGGTTT GTGAGGGGTGTTTGATGACTTTGACAGAATAAATATCTAAACAATTATCCTTGTTACTGCTTTGCCAGTTCTACGTTATTTACAATTATTCAGCTCTTGC AATAAATGTTCTGAATTCCTGA

refseq_PCDH9.F1 (forward primer)
refseq_PCDH9.R1 (reverse primer)
Single exon skipping

Frame 0

RERRGRRREGQRGRERGRARETERSASESLKHA RDNRLGIFRATVTRIAVRESSSPQL*RFLQEVRD LSSIGIGWKWYACCCGKYP*AEEVQLCVVCAKC PEEPRPSG*ERRNVERMTNDKSVNLFSGVANLP ARSNTFYKEETFCCF*FLPKLVLPDAWLSMCWNK SFLTAAYWERGKVEATNRLSPNK**DIMHPPVH ARFLLQFVHHSSVETFKP*NPGKENKYIIMDLR DFYLLAALIACLRLDSAIAQELIYTIREELPENV PIGNIPKDLNISHINAATGTSASLVYRLVSKAG DAPLVKVSSSTGEIFTTSNRIDREKLCAGASYA EENECFFELEVVILPNDFFRLIKIKIIVKDTNDN APMFPSPVINISIPENTLINSRFPIPSATDPDT GFNGVQHYELLNGQSVFGLDIVETPEGEKWPQL IVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAIL QVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSV IQLHATDADIGSNAEIRYIFGAQVAPATKRLFA LNNTTGLITVQRSLDREETAIHKVTVLASDGSST PARATVTINVTDVNDNPPNIDLRYIISPINGTV YLSEKDPVNTKIALITVSDKDTDVNGKVICFIE REVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFK IVASDSGKPSLNQTALVRVKLEDENDNPPIFNQ PVIELSVSENNRRGLYLTTISATDEDSGKNADI VYQLGPNASFFDLDRKTGVLTASRVFDREEQERF IFTVTARDNGTPPLQSQAAVIVTVLDENDNSPK FTHNHFQFFVSENLPKYSTVGVITVTDADAGEN KAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDN SPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVD VDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLE EKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVF LYVNDTAGNASYIYDLIRRTMETPLDRNIGDSS QPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRC RHASRFKAAQRSKQGAEWMSPNQENKQNKKKKR KKRKSPKSSLLNFVTIEESKPDDAVHEPINGTI SLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKH YKSASPQPAFHLKPDTPVSVKKHHVIQELPLDN TFVGGCDTLSKRSSTSSDHFSASECSSQGGFKT KGPLHTRQCNSHSKSDNIPVTPQKCPSSTGFHIQ ENEESHYESQRRVTFHLPDGSQESCSDSGLGDH EPVGSGTLISHPLPLVQPQDEFYDQASPDKRTE ADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGH SDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKD KLVNGHTLTRAWKEDSNRNQFNDRKQYGSNEGH FNNGSHMTDIPLANLKSYKQAGGATESPKEHQL* EKAIWDLITLNRHANTVCVRALCIQ*ISTTMPL LAGIPITLC*HHGEYNVFATYERR*F*PCNFVY *N*LHSPEISPLCKFFLLLHFILTLDCCYEQ*NM HLESKKVSWIRVTEKHIQLENCAFFFFFFFFCH *FVLGLLYLTLYCKQNLKR*ALNLLCC*QR*WT LVSQSVLKYL*IEASYY*QLLCTYNVHLKML*HN SVFYGCFCPSFYLPLCCYFCCFFQ*GVSVLVVC LDTHCSNNLKHLCLKKVLKSCFSYDSL*CRNSV NNKDERKNENFIQKRTSAKAWKFRTYFLSSYFQS RQKQNHLISTIK*ESNGKLLSIKSDIISCTCHS CKTNVSKLAYMEEKSLFKNSFNWANVCLQLC*N GRVCVDPHIQ*CCCNTSVIRP*PQNI*CVVPS*C NRTFSR*GSWGK*RDKSLIIAV*LFVIIVGQCL AGTSILSLRSNQ*SDN*C**DLSCTCKQIQIRT FLGGFC*GMTDDLNK*IACNKMSLLKEVEVILMP RFTINLKVKKTKKKQKI*KKGLLI**LICSYQK IKLLCK*QFTFFHSIMENNG*GCIAY*STFLSV CEGCLMTLTE*ISKQLSLLLLCQFYVIYNYSALA INVLNS*

Frame 1

ERGEGEGERGRGEGREGEHARRKGAPQSL*STQ EITD*EFFGQLSPG*LSENHHHRNSDVSYKKLE T*AVLASDGNGMHAAVENIPELKKCNYVLCVLNA QKNPDPVGKRDEMWRE*LTTNP*ICSLELLICQ PEATHFTRRKHFAASDFSPNWCYQMHGFLCVGT NHS*LQHTGKGERLRQLTGCLQISDEI*CILQSM HASSCNLCIIPQWKPLNPKIQEKKINTLSWT*G IFTCWLL*LPV*GWIPQ*LKNLFTLLERNCLKM CP*ETYQRI*TFLTSMLPQGPAPALSTDWFLKLG MPLW*KFPAALGKFSQPPTE*TEKNSVLAPHML RRMSVSLNLRW*SSPMISSG*SK*K*LSRIPMI MPPCFHLLSSIFPFQKTL*STAAFQFHQQQILTQ ASMVYSIMNC*MGRVFLDWISWKLQRERSGHN* LFSKTWIENRKIPM**KSK*RMEALHRNPVRPY CRSQ*VM*MTTGQCLKRVKWRCIFQRMLP*VPL* FSSMPLMQI*AVMLKSGTFLVPRSPLQPKDSLL *IILLG*LQFRGP*IERRQPFTK*QCWLVTAAP LLLEQRLPSMSPM*MITLLI*TSGTL*VPSMAPC IYLRKILSIQRLP*LQFQIRTQM*MAK*SVLLK ERSHFI*RRYMTTNIC*RPLLCWTMRAPKNSAL KLLPLILGSPV*IRLPW*GLSLRMKMTTHQFSTS L*LSCQFLKTTDVGYT*QLLVPQMKTVGKMQTL FISLDRMPPSLIWTEKQEF*QPPEYLTEKNKND SFLQ*LPGTMGPLPSKAKRL*LLLFWMRMTIAPS LLIIIFNFLCLRICQSIVLWG*SQ*QMQMLERI KL*LFPF*MTMIILCWIPILES*SQMSHLIESS RVPTLLMSKPLMEDNHLVPLLQK*LSTSWMSMTT AQLSFLHRLILPLSWCPSQPFLAPW*QKFLQWM LTLE*TLN*SIL**VETIKAYSGLIQ*QVTLLW KKNQHLLMWDCIVWWST*VTWGTLSLCTRLCLYS FMLTTLLEMPPISMT*SAGLWRPRWTGT*GIVA NPIKMRTI*PS*LPSSPVPWWSLL*SSSPFWCA VAMHQGSKQLRGASKVPNGCPQTRRTSKTRKRKE RKGSLPKALF*TLLLSKSPNPMMQFMNLSMGQ* ACRLNWRSKV*EDLTGARHLQQHSSLTVLTWPS TTNLLLHSLLFISNQTLQFP*KSTT*FRNSLWTT PLLGVVTPFLNALPLVQITSVPQSAVPKEASRQ RAPYTPDSVTHTAKVTIFLSLLRNVPAPRVSTF RRMKKAITSRSAVLRFISLMAPRKAAVTVV*ETM SRWVVEP*SHTLFLWFSHRTNSMTRPLRTRGLK QMATLIPTLMGLWVPED*LKLQRCALKSAWFWV TLIIAGCLLAWVHINTPNLLSQPLHPRKNG*RRT SL*MGTP*PEPGKKTATGTSSMTVSSMAPMKAI STMAAT*QTFLWQI*SLISKQEVLLRVLRSTNS KKRLYGT**L*IDMLIPCASELYVFNRSLQLCPF *QGYL*LCVSTMENTMFLQHMREDSSSHAILFT RIDYTLQRSLHCANFFYYCILF*PWTAAMNNRI CIWKVRKFHGLE*LKNISS*KIVLFFFFFFFFVI DLCWDCYT*HYTANKT*RDKH*TYCAVNNVSGH L*VNQC*SICK*KQAIINNFCVLIMFT*KCCSI ILCFMVASVLLFIYLFVVIFVVSFSEVFLC**SV LTHIVQTISSTCV*KRF*NLASHMIAYDAGIL* TIKMKEKMKTLYKKGLLQKLGNSEPIFYHLIFK VGKSKIT*LVPLSERVMENCYPSKVI*YPVLVTH VKLMYQN*HIWKKNHYSKIVSIGQMCVYNFVEM AESVLILIYNNVVVTQVLLDHSHKIFNVLCLHD VTEHSPGRVVGGNKGINL*LLLFNCLLS*LVNAW QVPAYCHLGQTNKVTTNVNKISVARANKSKFEH S*EVFVKA*QMI*TNK*HATKCLY*KKWKLS*C HGSPSI*K*KKQKKNKKFKKKVC*SDS*FVLTKK *NYFVNSSSHFSTV*WKIMGRGALLIEVHFCRF VRGV**L*QNKYLNNYPCYCFASSTLFTIIQLL Q*MF*IP

Frame 2

REEREKERGAEGKGERESTRDGKERLRVSEARK R*PIRNFSGNCHPDSCQRIIITATLTFPTRS*R LKQYWHRMEMVCMLLWKISLS*RSATMCCVC*M PRRTQTQWVRETKCGEND*RQIREFVLWSC*FAS PKQHILQGGNILLLLISPQTGATRCMAFYVLEQ IIPNCSILGKGKG*GN*PAVSK*VMRYNASSSP CTLPLAICASFLSGNL*TLKSRKRK*IHYHGPEG FLPVGCSDCLFKAGFRNSSRTYLHY*RGIA*KC AHRKHTKGSEHFSHQCCHRDQRQPCLQTGF*SW GCPFGESFQQHWGNFHNLQQNRQRKTLCWRLIC* GE*VFL*T*GGDPPQ*FLQADQNKNNCQGYQ** CPHVSISCHQYFHSRKHFDQQPLSNSISNRS*H RLQWCTAL*IVKWAECFWTGYRGNSRGREVATTD CSAKLG*RTERYLCDENQSRGWRHSTEIQYGHT AGHSK*CK*QQASV*RGSSGGAYSRECSRRYLC NSAPCH*CRYRQ*C*NPVHFWCPGRPCNQKTLCF K*YYWADYSSEVLR*RGDSHSQSDSAG**RQLH SCSSNGYHQCHRCK**PS*YRPQVHYKSHQWHR VFI*ERSCQYKDCPNYSFR*GHRCEWQSDLFY*K RGPISFEGGI*QPIFVRDLFFVGL*GHQRIQL* NCCL*FWEAQFKSDCPGKG*A*G*K*QPTNFQP ACN*AVSF*KQPTWVILNNY*CHR*RQWEKCRHC LSAWTECLLL*SGPKNRSFDSLQSI*QRRTRTI HFYSNCQGQWDPSPPKPSGCDCYCSG*E*Q*PQ VYS*SFSIFCV*ESAKV*YCGGNHSDRCRCWRE* SCDSFHSK*Q**FCVGSLFWSHKVKCLI**RAA EFLHF*CQSH*WRTTTSFLYCKSNYQRHGCQ*Q QPSCHFSTV*YFL*VGAPLSHSWLRGSRSFCSGC *HWNER*TKVYYSEWKQ*RLIPD*SSNR*HYSG RKTSTY*CGIASFGGQHK*PGVP*VFAHACACI PLC*RHCWKCLLYL*LDPQDYGDPVGQEHRG**P TLSK*GLSNHHDCHHRRCHGGHCCDLRHRSGAL SPCIKVQSSSEEQARCRMDVPKPGEQAKQEKEK KEKEVSQKLSFELCYYRRVQTR*CSS*TYQWDNK PAG*TGGAKYRKI*LGPGTSNNIQA*QS*PGQA LQICFSTACFSSQTRHSSFREKAPRDSGTPFGQ HLCWGL*HPF*TLFH*FRSLQCLRVQFPRRLQDK GPLTHQTV*LTQQK*QYSCHSSEMSQLHGFPHS GE*RKPLRVAAPCYVSSP*WLPGKLQ*QWSRRP *AGG*WNPDLTPSSSGSATGRIL*PGLSGQED*S RWQL*SQL*WAFGSPRIS*SYRDVHSRVLGFGS L**LLDASWLGSISTPQISSLNLCTPERMGEEG QACEWAHPDQSLERRQQQEPVQ*P*AVWLQ*RPF QQWQPHDRHSSGKSEVL*ASRRCY*ES*GAPTL RKGYMGPNNFK*TC*YRVRQSFMYSIDLYNYAP SSRDTYNFVLAPWRIQCFCNI*EKIVLAMQFCLL ELITLSRDLSIVQIFFIIAFYFDPGLLL*TIEY AFGK*ESFMD*SD*KTYPVRKLCFFFFFFFFLS LICAGTAILDIILQTKLKEISIKPIVLLTTLVDT CKSISVKVFVNRSKLLLTTFVYL*CSPKNVVA* FCVLWLLLSFFLFTSLLLFLLFLSVRCFCVSSL S*HTLFKQSQALVFKKGSEILLLI**LMMPEFCK Q*R*KKK*KLYTKKDFCKSLEIQNLFFIILFSK *AKAKSLN*YH*VRE*WKTVIHQK*YNILYLSL M*N*CIKISIYGRKITIQK*FQLGKCVSTTLLKW QSLC*SSYTIMLL*HKCY*TIATKYLMCCAFMM *QNILQVG*LGEIKG*ISNYCCLTVCYHSWSMP GRYQHIVT*VKPIK*QLMLIRSQLHVQTNPNSNI LRRFLLRHDR*FKQINSMQQNVFIERSGSYLNA TVHHQFKSKKNKKKTKNLKKRFANLIVNLFLPK NKITL*IAVHIFPQYNGK*WVGVHCLLKYIFVGL *GVFDDFDRINI*TIILVTALPVLRYLQLFSSC NKCSEFL