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Sequences

Sequence NM_007050

CCTCCCGCCTCAGTTCGCGCCGCGCCTCGGCTTGGAACGCAGGAGCGCCGGCTCCGGGAGCCCGAGCGGAGCCAGCCGCGCGCACAGCCAGCGGCCGCGC
CGGCGATGCGGGGCCACCCCGCGCCCGCCCCAGTCCCGGCCCCGGCCCCCGCGGGAAGGGGCTGAGCTGCCCGCCGCCGCCCGGATGGCGAGCCTCGCCG
CGCTCGCCCTCAGCCTGCTCCTGAGGCTGCAGCTGCCGCCACTGCCCGGCGCCCGGGCTCAGAGCGCCGCAGGTGGCTGTTCCTTTGATGAGCACTACAG
CAACTGTGGTTATAGTGTGGCTCTAGGGACCAATGGGTTCACCTGGGAGCAGATTAACACATGGGAGAAACCAATGCTGGACCAGGCAGTGCCCACAGGA
TCTTTCATGATGGTGAACAGCTCTGGGAGAGCCTCTGGCCAGAAGGCCCACCTTCTCCTGCCAACCCTGAAGGAGAATGACACCCACTGCATCGACTTCC
ATTACTACTTCTCCAGCCGTGACAGGTCCAGCCCAGGGGCCTTGAACGTCTACGTGAAGGTGAATGGTGGCCCCCAAGGGAACCCTGTGTGGAATGTGTC
CGGGGTCGTCACTGAGGGCTGGGTGAAGGCAGAGCTCGCCATCAGCACTTTCTGGCCACATTTCTATCAGGTGATATTTGAATCCGTCTCATTGAAGGGT
CATCCTGGCTACATCGCCGTGGACGAGGTCCGGGTCCTTGCTCATCCATGCAGAAAAGCACCTCATTTTCTGCGACTCCAAAACGTGGAGGTGAATGTGG
GGCAGAATGCCACATTTCAGTGCATTGCTGGTGGGAAGTGGTCTCAGCATGACAAGCTTTGGCTCCAGCAATGGAATGGCAGGGACACGGCCCTGATGGT
CACCCGTGTGGTCAACCACAGGCGCTTCTCAGCCACAGTCAGTGTGGCAGACACTGCCCAGCGGAGCGTCAGCAAGTACCGCTGTGTGATCCGCTCTGAT
GGTGGGTCTGGTGTGTCCAACTACGCGGAGCTGATCGTGAAAGAGCCTCCCACGCCCATTGCTCCCCCAGAGCTGCTGGCTGTGGGGGCCACATACCTGT
GGATCAAGCCAAATGCCAACTCCATCATCGGGGATGGCCCCATCATCCTGAAGGAAGTGGAATATCGCACCACCACAGGCACGTGGGCAGAGACCCACAT
AGTCGACTCTCCCAACTATAAGCTGTGGCATCTGGACCCCGATGTTGAGTATGAGATCCGAGTGCTCCTCACACGACCAGGTGAGGGGGGTACGGGACCG
CCAGGGCCTCCCCTCACCACCAGGACCAAGTGTGCAGATCCGGTACATGGCCCACAGAACGTGGAAATCGTAGACATCAGAGCCCGGCAGCTGACCCTGC
AGTGGGAGCCCTTCGGCTACGCGGTGACCCGCTGCCATAGCTACAACCTCACCGTGCAGTACCAGTATGTGTTCAACCAGCAGCAGTACGAGGCCGAGGA
GGTCATCCAGACCTCCTCCCACTACACCCTGCGAGGCCTGCGCCCCTTCATGACCATCCGGCTGCGACTCTTGCTGTCTAACCCCGAGGGCCGAATGGAG
AGCGAGGAGCTGGTGGTGCAGACTGAGGAAGACGTTCCAGGAGCTGTTCCTCTAGAATCCATCCAAGGGGGGCCCTTTGAGGAGAAGATCTACATCCAGT
GGAAACCTCCCAATGAGACCAATGGGGTCATCACGCTCTACGAGATCAACTACAAGGCTGTCGGCTCGCTGGACCCAAGTGCTGACCTCTCGAGCCAGAG
GGGGAAAGTGTTCAAGCTCCGGAATGAAACCCACCACCTCTTTGTGGGTCTGTACCCAGGGACCACCTATTCCTTCACCATCAAGGCCAGCACAGCAAAG
GGCTTTGGGCCCCCTGTCACCACTCGGATTGCCACCAAAATTTCAGCTCCATCCATGCCTGAGTACGACACAGACACCCCATTGAATGAGACAGACACGA
CCATCACAGTGATGCTGAAACCCGCTCAGTCCCGGGGAGCTCCTGTCAGTGTTTATCAGCTGGTTGTCAAGGAGGAGCGACTTCAGAAGTCACGGAGGGC
AGCTGACATTATTGAGTGCTTTTCGGTGCCCGTGAGCTATCGGAATGCCTCCAGCCTCGATTCTCTACACTACTTTGCTGCTGAGTTGAAGCCTGCCAAC
CTGCCTGTCACCCAGCCATTTACAGTGGGTGACAATAAGACATACAATGGCTACTGGAACCCTCCTCTCTCTCCCCTGAAAAGCTACAGCATCTACTTCC
AGGCACTCAGCAAAGCCAATGGAGAGACCAAAATCAACTGTGTTCGTCTGGCTACAAAAGGTGCCTCCACCCAGAATTCTAACACTGTGGAGCCAGAGAA
GCAGGTGGACAACACCGTGAAGATGGCTGGCGTGATCGCTGGCCTCCTCATGTTCATCATCATTCTCCTGGGCGTGATGCTCACCATCAAAAGGAGAAGA
AATGCTTATTCCTACTCCTATTACTTGTCCCAAAGGAAGCTGGCCAAGAAGCAGAAGGAGACCCAGAGTGGAGCCCAGAGGGAGATGGGGCCTGTGGCCT
CTGCCGACAAACCCACCACCAAGCTCAGCGCCAGCCGCAATGATGAAGGCTTCTCTTCTAGTTCTCAGGACGTCAACGGATTCACAGATGGCAGCCGCGG
GGAGCTTTCCCAGCCCACCCTCACGATCCAGACTCATCCCTACCGCACCTGTGACCCTGTGGAGATGAGCTACCCCCGGGACCAGTTCCAACCCGCCATC
CGGGTGGCTGACTTGCTGCAGCACATCACGCAGATGAAGAGAGGCCAGGGCTACGGGTTCAAGGAGGAATACGAGGCCTTACCAGAGGGGCAGACAGCTT
CGTGGGACACAGCCAAGGAGGATGAAAACCGCAATAAGAATCGATATGGGAACATCATATCCTACGACCATTCCCGGGTGAGGCTGCTGGTGCTGGATGG
AGACCCGCACTCTGACTACATCAATGCCAACTACATTGACGGATACCATCGACCTCGGCACTACATTGCGACTCAAGGTCCGATGCAGGAGACTGTAAAG
GACTTTTGGAGAATGATCTGGCAGGAGAACTCCGCCAGCATCGTCATGGTCACAAACCTGGTGGAAGTGGGCAGGGTGAAATGTGTGCGATACTGGCCAG
ATGACACGGAGGTCTACGGAGACATTAAAGTCACCCTGATTGAAACAGAGCCCCTGGCAGAATACGTCATACGCACCTTCACAGTCCAGAAGAAAGGCTA
CCATGAGATCCGGGAGCTCCGCCTCTTCCACTTCACCAGCTGGCCTGACCACGGCGTTCCCTGCTATGCCACTGGCCTTCTGGGCTTCGTCCGCCAGGTC
AAGTTCCTCAACCCCCCGGAAGCTGGGCCCATAGTGGTCCACTGCAGTGCTGGGGCTGGGCGGACTGGCTGCTTCATTGCCATTGACACCATGCTTGACA
TGGCCGAGAATGAAGGGGTGGTGGACATCTTCAACTGCGTGCGTGAGCTCCGGGCCCAAAGGGTCAACCTGGTACAGACAGAGGAGCAATATGTGTTTGT
GCACGATGCCATCCTGGAAGCGTGCCTCTGTGGCAACACTGCCATCCCTGTGTGTGAGTTCCGTTCTCTCTACTACAATATCAGCAGGCTGGACCCCCAG
ACAAACTCCAGCCAAATCAAAGATGAATTTCAGACCCTCAACATTGTGACACCCCGTGTGCGGCCCGAGGACTGCAGCATTGGGCTCCTGCCCCGGAACC
ATGATAAGAATCGAAGTATGGACGTGCTGCCTCTGGACCGCTGCCTGCCCTTCCTTATCTCAGTGGACGGAGAATCCAGCAATTACATCAACGCAGCACT
GATGGATAGCCACAAGCAGCCTGCCGCCTTCGTGGTCACCCAGCACCCTCTACCCAACACCGTGGCAGACTTCTGGAGGCTGGTGTTCGATTACAACTGC
TCCTCTGTGGTGATGCTGAATGAGATGGACACTGCCCAGTTCTGTATGCAGTACTGGCCTGAGAAGACCTCCGGGTGCTATGGGCCCATCCAGGTGGAGT
TCGTCTCCGCAGACATCGACGAGGACATCATCCACAGAATATTCCGCATCTGTAACATGGCCCGGCCACAGGATGGTTATCGTATAGTCCAGCACCTCCA
GTACATTGGCTGGCCTGCCTACCGGGACACGCCCCCCTCCAAGCGCTCTCTGCTCAAAGTGGTCCGACGACTGGAGAAGTGGCAGGAGCAGTATGACGGG
AGGGAGGGACGTACTGTGGTCCACTGCCTAAATGGGGGAGGCCGTAGTGGAACCTTCTGTGCCATCTGCAGTGTGTGTGAGATGATCCAGCAGCAAAACA
TCATTGACGTGTTCCACATCGTGAAAACACTGCGTAACAACAAATCCAACATGGTGGAGACCCTGGAACAGTATAAATTTGTATACGAGGTGGCACTGGA
ATATTTAAGCTCCTTTTAGCTCAATGGGATGGGGAACCTGCCGGAGTCCAGAGGCTGCTGTGACCAAGCCCCCTTTTGTGTGAATGGCAGTAACTGGGCT
CAGGAGCTCTGAGGTGGCACCCTGCCTGACTCCAAGGAGAAGACTGGTGGCCCTGTGTTCCACGGGGGGCTCTGCACCTTCTGAGGGGTCTCCTGTTGCC
GTGGGAGATGCTGCTCCAAAAGGCCCAGGCTTCCTTTTCAACCTAACCAGCCACAGCCAAGGGCCCAAGCAGAAGTACACCCACAAGCAAGGCCTTGGAT
TTCTGGCTCCCAGACCACCTGCTTTTGTTCTGAGTTTGTGGATCTCTTGGCAAGCCAACTGTGCAGGTGCTGGGGAGTGGGAGGCTCCCCTGCCCTCCTT
CTCCTTAGGAGTGGAGGAGATGTGTGTTCTGCTCCTCTACGTCATGGAAAAGATTGAGGCTCTTGGGGGTCACTGCTCTGCTGCCCCCTGCAACCTCCTT
CAGGGGCCTCTGGCACCAGACATTTGCAGTCTGGACCAGTGTGACCTTACGATGTTCCCTAGGCCACAAGAGAGGCCCCCCATCCTCACACCTAACCTGC
ATGGGGCTTCGCCCACAACCATTCTGTACCCCTTCCCCAGCCTGGGCCTTGACCGTCCAGCATTCACTGGCCGGCCAGCTGTGTCCACAGCAGTTTTTGA
TAAAGGTGTTCTTTGCTTTTTTGTGTGGTCAGTGGGAGGGGGTGGAACTGCAGGGAACTTCTCTGCTCCTCCTTGTCTTTGTAAAAAGGGACCACCTCCC
TGGGGCAGGGCTTGGGCTGACCTGTAGGATGTAACCCCTGTGTTTCTTTGGTGGTAGCTTTCTTTGGAAGAGACAAACAAGATAAGATTTGATTATTTTC
CAAAGTGTATGTGAAAAGAAACTTTCTTTTGGAGGGTGTAAAATCTTAGTCTCTTATGTCAAAAAGAAGGGGGCGGGGGAGTTTGAGTATGTACCTCTAA
GACAAATCTCTCGGGCCTTTTATTTTTTCCTGGCAATGTCCTTAAAAGCTCCCACCCTGGGACAGCATGCCACTGAGCAAGGAGAGATGGGTGAGCCTGA
AGATGGTCCCTTTGGTTTCTGGGGCAAATAGAGCACCAGCTTTGTGCATAATTTGGATGTCCAAATTTGAACTCCTTCCTAAAGAAACCCAGCAGCCACC
TTGAAAAAGGCCATTGTGGAGCCCATTATACTTTGATTTAAAATAGGCCAAGAGAATCAGGCCTGGAGATCTAGGGTCTTGTCCAAAGTGTGAGTGAGTC
AATGAGAGGGAACCAACATTTGCTAAGTCTCTACTGTATGCCAGGGATCATGCTTGGCACTTTCCATAGGACATTTCACACAGTCCTTAGAACCCCCAGG
AGAGAGCTACTGACTTGTTATCATCTCCATTTGATCATCTCCTCCAATGAGGAAACCCACGCACCTTCCTTAGTAATGAAATCCTGGGTTCCAAAGGGGC
AGGTAATGGCAATGAGACTTCTCCGTGCTGTTTTCTTCATCTTCTCTAAGCCAAGCAATTATTTTATGGAGGGAAAATAAGGCCAGAAACTTCTGAGCAG
ATAACTCCACAAATGGAAATTTAGTACTTTCTTCCTGATGCCAGTTCTTCTGGGAAGCGCAGAATTTCAGATATATTTTAGTAACACATTCCCAGCTCCC
CAGGAAAGCCAGTCTCATCTAATTTCTTAGTCAGTAAAAACAATTCCCTGTTCCTTCAGGCTATGAATGGACCAGCCAGGGAAACTCTCGACCTTGATCT
CTAGCCAGTGCTTAGGCCCAATATCTGACAGCCTCAGGTGGGCTGGGACCTAGGAAGCTCCATCTTGAAGGCTGGTCTAGCCCCAGACAGGGCATGAGGG
GCAGAGAATTCAAGAAGGTACAGCTTTGGCCCTCAAGAGCCCACTGTATGCTGGGGAAATGGAACCATGGTGCAGTAGTGTGGAGTGGATGAGTGTTCCA
TGAGCCTAGGAGCAAGAAAGTCTCTTCGGCCTCGGGCTTCCTGGAGAAGGGGACGTCCATTCCTGCTGGGTCTTAACAAGCATAAAAAGGAAAAAAAGGA
AACTCAGGCAAAGGGATCCATATGTGCAATGGCAAAGAAATGTGAAAAGGCATTGGGAGAAGCAGTCTGGGGGAGGCCAGCCCAGTGCGGGCACAGCACA
ACACGGGGAGCAGCAAGAGATGAGCCAGGGTCCAGGAGACAGATGCCCATCGCGAGTACAGACTTTGTCCTATTGGCAACAAGGAGTCCATGGAGCTTTA
GAGAGATGCACTCAGCTTCGTGTTGGCCAAGACTCCTTCTGGGCCAATGGGGCTGCCTCTTTTCCTTTCATCAGACACTGTGAAAACATTCCCTTAAGCG
TGCACTTTTTAATATCACATCTATTTGTCTGTCTGCTCATTGTTTTGTTGCTGGAACTAAATATGCAATGGATCATGAGACTCAGATTCTATGAGAAACC
CAGGGTCTCTGCTTTACCACGGAGCAGGGTCACCAACCCAGATCTCCAGGCCCATGAGGATGGAACATGAAAGGAGCCGACAAAAGTTGCTTCCATTGGC
ATGGGCTCTGGAGCTGTCCAGAAGTCCAGGGACACCAGACTTGATCAAGGAAGGGCTGTCACTTTAGAGGTTCAAAAGGAAGTGCCTCAAAGCAAAGGCA
AGCAAAGGAACCCCACGATGAACTTGCTCTTTTCCTTTGATGAGCCTCTCCCCAGGTGTATTTCAGCAGACCCCGGGGACCCACCCCCACTGGGCCTGCT
GGCCTCCCTCGGCTCCAGCCCAATGCCCCAGCTGGCCTTCCCCAGCCTGCAAGGAGCCTGTAGCATGGCAAATCTGCCTGCTGTATGCTATTTTCTTAGA
TCTTGGTACATCCAGACAGGATGAGGGTGGAGGGAGAGCTATTTAACACAAATCCTAAGATTTTTTTCTGCTCAGGAAGGGGTGAAATAGCTGGCAGATA
CAAAAGACAGTGGCTTTTATCATTTTAAATGGTAGGAATTTAAGGTGTGACTTCAGGGAGAAACAAACTTGCAAAAAAAAAAAATCTCAGGCCATGTTGG
GGTAACCCAGCAAGGGCCAGTGATGATTTCCCCCAGCTCATCCCCTTATTTTCCCACAACCCAACCATTCTCTAAAGCAGGACAGTGAATAGGTCTTAGG
CCAGTGCACACAGGAAGAAATTGAGGCTTATGGATGGGGATGACTTCCCTAAGATCCCATGGGACAAGGATGTGGCAAGGCTTGGATGAGATGGGGCACC
AGTGCCCAGGAATTTGAACATTTTCCTTTACCCAGGAAATCTCCGGAGCCAACACCACCACCCCCAGGGGGTCTCCCCACCCCACCCCATTTACAGGGTG
AGCTCAGCCTGTCATGAGCAGAGGAAAATATTATTAATGCTCTCTGAGTCTTTACAACAGGAGCTCTTACCTCATAGATGTGGGCTCTGTTTGGGGAAGA
TGCAAGGAAGTAATGAGAAGCCCAGGAAATTTCTCCACCTGTGTTTATGGCCTAAATAGCTTCAGGATGTATCTTAGCTGCACTCCAACATTGCATCCTT
TCTGGGGTGAAGAATCTGGGCCAACCAGGGGTCCTTGGGCCTCTAGAAGGCCACAGTAGGCCTCTCTTTGTGGGAATGGAAGGGGACAGTTTGCTTTTAG
TGCTGGCCCTCTCTGTGGGTGTGGCCTGCAAAGGAACCAACAGACCCTATGCTGGGGACTCTAACATGTGAGCTCATTAAATTCTTCCAGCATTCTAAAG
GAGGGTTTGTGATTGTCACCATTTACTGATGAGGAAACTAAGGCTCCTAGGGGAGAAATCACTTGCCCACAGTTCCACAGCTAGTGAGTGAATGAACCAG
GATTTAAACCGGTTTTTTCTCACTACAGAGACAATATTTTTCCACCATTGTATCTCACATTTTTCCCAGGAGGTTACCCATAACAGAAGAGACTAGAGTG
GAACAGATACGTCAGTGGATAAAGCTCAAAGCAAACAACAGTAAGCTTAAAATTCCTTCATAGTCTCATGTTTTACGTTCACAATTCATGCAAAATTTGC
ATTCCACTTTCTGATTTAGCCTTGTTGGTTTTAATATGACTCTATGAATATTTCAAAAAAAAATGTGCTCTGTTCCTCATGTTGTTCTGTTCTGTTCACC
CCGCTATGACGGACCCTAGGTCAGCTGGTCTTCAGCTTGACCCTAGAATTGACTCTAGGAGCAGTGACCCTGCTGCCTCCCAGAGCCAGTTATAGGCTCA
AGATCAAGACCAACTGACCTTCTCCTAGGCAGCTCCTTTGGTGTGTGGGTGCTCTGACCTCACTGTTCATGAGGGGACCTCAACTAAGGCATCTTCCAGT
TGGGTGCTGGAAGGAACCCATTAACTCACACTAGAATGATGAGGATTTGCTCATCTGGCGTGGAGAAGGATGAGCCCACAAAACCCTAAAGGGAAAAGAG
AAGCTGGACACAGCTGTACTCAGCAGATTCCTGAATGCTAGGCTGGAAAGTGGTGCCTGTTGTCCAAGTGGAGTCACATGGTTGCTAATGTGGGCAAGTC
TGAGGACACACTTCATGAGCAGCTGGGGTCTGGAAGGCTCCTCACTTTACCCTAGCCACACATAATTACTGGGTGCCTACAGCACCTAGCACCTTGGAGG
GGGCACTATTAGGAAATCGAGATTACTATGGCACAATTAATTCCTGGGTAAGGCATGGGGTTGTGGTGGACAGAGCTCAGTCTTTAGTTTGAACGAAAAC
ATACATACATGAAAAACATACATGAAAAAAGGACCCTCATCAACATTAGAAGGGGTAGATTTGGAGCACTTTAGGCAGGAAAACAGGAACGCAAGGCCAG
GAAACTGGAACCCAGTGAATACTCAGAACCGAGGATGCAGATGACTTATTTAGCAAAATGGTCACTTCTGTGACATAGCTGGAGAAAGGATGGGTAACAG
CTTGCCAGAGCCACTTGGAACAAGGGCAAATCTCAGTGTCTGGGGCAAAAGATGATGCATTTCCCTCTGACCCATCATGTTTATTCATCCTCCACTCCCC
ATTGCCACACTAGCTCTTGCTGTAAGTCCTCACCAGGATCTACATTTCCTCGTCGCTGGTGGGAACCCCTTAGAGTACATAGAGGTATCAGTCCAGTAAG
ACTGCTCTACACAACAGAAGTGAGGCCCAGGGAGTAGCAGCCAGGCCCTTATCCTGTTACCTCTGCAGGAGTGACTGCCCAACCCAGATCCAGAGACATT
GAAGGAAATGATAATTCCTTGGTACCTCACTGCCTTGGGACAAAATGAAGAAAGCCACCCTTCCTTAGGCTGCAGCTTGCCACTCCTGGGCTGGGTAAAC
AGGTCATCAGCACCAAGCTCAACCAGGAGTAACACTCTGGAAGACATGGGTGAGCCCAAGAGGAAGCATGAACAGGACGCTGTTCCTAAGTCATGTCAAC
AGGTTGTGCTGGGCCAGGATCCCCAGGGAAAAAAATGGTCAACCCAACTGGAGGGTAGGTTAGAAGAAAAAAAACATAAACGTGGATAGTCATGTCATCT
CAAATCCCTGACTTGGCTTCCCCATTACTTAACAGTCTGAGCTCCTTCTTAGCCTGTGACCAGCTTCAAATCACAGCCAAGTAAAACAAGGAAATAGGAA
AAGTAAATCCAACTAGAAGAGACAAGCTGAGATTCAGATTTGTTTACTCCTCCCATGCAAAGTTTCCCTGTTGGAGGTTTTCCATGTATACATGTCTAGA
AGTGATAGAATGCAAGGCCTTGGCTTTGTCTTGCAGGGATCTGCCTTTGAGGTCATAGACTGAACAGCAGGGAGAGAGGTTAGTGGTGGAGTGTGGGGGG
AGCTGTTCTAGCTCCAGTTTCTTCTGACACATTTTTCAGGATCATGGATCTGATCCTCCGAAGCACAGCAGAGATATCTAAGCCATATTTGTGCACATGA
GCAGACTCTTCTAGTTTTTTAGTAACCAGGGATGGGCTTTTGCATGGCACTGACTATAGAGATGTCTTGTAGAGATCAAGCCAGTCTTTTGCATCCCACC
TGCCCACCTCCAGAAGAGATGGGAAAAGGTCATCAAAGGGCATTCACCAACTGAAATCCACTCATGAATGTTAGGTCTCTAAAAGGAGGCATCAACACTC
ACAATGGTAGCCTCCAAACCTAGCATCCCACCTATCTAAGAGCTCAGGGGTGGTCCACTGGGGCAGATACAAGGGAAGTGCAAGGGCTCAGGATGAAAGA
AAATCTATTGGGAAGAGTTTTAGGGGCTTGATCATTATGGGGCTTCCTTCTATATCTGAGAACTGCTCTGGGTGGTGAGATGTGGACTCTGATCCTTAAT
TGGAATGTTCGGAGAATGAGTGTCTGGTGGCCTTGAAGTGTTGGACAGAAAAGTATCAGTATAAAAGCCTGGAGCTCAGGGTAATTAATGTAGTTCATGG
TTCCTTAGTGAGCAGGACTCTTGGATGTGGAGGAGAAAGGGTCATAGGAAGTAAACCACCAAAATTACAAAATTGAGTCTCTGTACAATTACTTCAGTGC
CTTTGGGCTTATGAATACAAATCAGTGGGCCTTCTCTATGATGGTCCAACAAACTCTCAGTGTCCACCCTGTCCCTGTATCTCCCATGGAAGATGAATAA
TGTCAGGTGTTCTTTGGGTCAAAGGCCCCAGGGCAGTCTGGAGGCTTAGAGGGCAGAGTGGTGTCATTCCATGTAAAGTTAGGCTTCTGAGGGGTCAGGC
AGAATATGGTGTCCATATCTTCCATAGCTCTGCAGATTCTTGGATGAAGTCAAGCACAGTTTGCTAGACCCAGGTCACTCCTCTGAGTATAACTAGGACC
CATGAGTGAAACTTAATAGCTGTAAGGAAGAACCTGCTGTCTGCCAGAGAGGATAAGCTGCCCATCTCAGCAGCTGTCTAAAAGAAGGCAGGTGTCTCTT
TAAAGGGAAGAGAAGCATTGGTGAAATGGATTTCAGGTCACTTCCATTCCAGATGGGTGAGATCTTGTGGAGCTGGGATCATGTTTGAACTCATTCATAC
CTGTAGAGCACGAATCCAAGTAGATTGTGTTTGGTCTGTACAGGCTGAAGCCCCCTGCTCTCCCACCCAAGTGCCCCCACTGAGCAGGCCAACATGCTGT
TGTGGCCACATATACTGGGCTGATCCAGGCTGGTTATCACCAAACAGCAAACCATAGGGAACAGCTGCTTTGCCATAGACCCAATACCCATGTAGATCTC
TCATGAGAGCAGCCATAACTCAGACCCACTGACCAACAGGGCCATGAGTGACAGCCAGAACCAGTGAAGGTCCAAGTAGGACACAGAGCAGGGCTTTTCT
TACCATACACATTATCTCCAGAGGTTATTTCTACCCCACTCCCTATTCAAGGCCTGTTGGAGCACACTGCAAAAGCAAAAGCACAGTAACTCAATTTACA
CATGATTATAATCATTTCCAGTGCACACATTTCATCACCAGGTGGATCCTGAGCTAGCCCATGTAAATCCGGGTTAACCCATATTGGTAATCATACTCAA
AAGCACTTTTCACCCTACATTCTACTAGCCAATCAAAGACAAAGAGTTGTGGCCTCTACCATTGCCTTGGCTTCTGGACACCCTCACAAGCTATCCCAAG
GTTCCCGCTCAACTCCAGGGAGGCTGACATCTTCACATCCACTGGGCATATAATATTGCATGAGACCAAAGTCTCCACACTCTTTGCAGCCTCCTCCATG
AATCCCAATGGCCTGCACTTGTACAGTTTGGGTGTTTGATAGATAAAGCACGTATGAGAAGAGAAAACAAAATAAATCAACTTTTTAAAAAAGCCAGCAC
TGTGCTGTCAATGTTTTTTTTTTCTTTTCAATTCTAGCTCAGAAAAGCAGAAGGTAAATAATGTCAGGTCAATGAATATCAGATATATTTTTTGACTGTA
CATTACAGTGAAGTGTAATCTTTTTACACCTGCAAGTCCATCTTATTTATTCTTGTAAATGTTCCCTGACAATGTTTGTAACATGGCTGTGTTAAAAAAT
CTATACAATAAAGCTGTGACCCTGAGATTCATGTTTTCCTAAGATA
  • refseq_PTPRT.F1 (forward primer)
  • refseq_PTPRT.R1 (reverse primer)
  • Single exon skipping

Frame 0

PPASVRAAPRLGTQERRLREPERSQPRAQPAAA
PAMRGHPAPAPVPAPAPAGRG*AARRRPDGEPRR
ARPQPAPEAAAAATARRPGSERRRWLFL**ALQ
QLWL*CGSRDQWVHLGAD*HMGETNAGPGSAHR
IFHDGEQLWESLWPEGPPSPANPEGE*HPLHRLP
LLLLQP*QVQPRGLERLREGEWWPPREPCVECV
RGRH*GLGEGRARHQHFLATFLSGDI*IRLIEG
SSWLHRRGRGPGPCSSMQKSTSFSATPKRGGECG
AECHISVHCWWEVVSA*QALAPAMEWQGHGPDG
HPCGQPQALLSHSQCGRHCPAERQQVPLCDPL*
WWVWCVQLRGADRERASHAHCSPRAAGCGGHIPV
DQAKCQLHHRGWPHHPEGSGISHHHRHVGRDPH
SRLSQL*AVASGPRC*V*DPSAPHTTR*GGYGT
ARASPHHQDQVCRSGTWPTERGNRRHQSPAADPA
VGALRLRGDPLP*LQPHRAVPVCVQPAAVRGRG
GHPDLLPLHPARPAPLHDHPAATLAV*PRGPNG
ERGAGGAD*GRRSRSCSSRIHPRGAL*GEDLHPV
ETSQ*DQWGHHALRDQLQGCRLAGPKC*PLEPE
GESVQAPE*NPPPLCGSVPRDHLFLHHQGQHSK
GLWAPCHHSDCHQNFSSIHA*VRHRHPIE*DRHD
HHSDAETRSVPGSSCQCLSAGCQGGATSEVTEG
S*HY*VLFGARELSECLQPRFSTLLCC*VEACQ
PACHPAIYSG*Q*DIQWLLEPSSLSPEKLQHLLP
GTQQSQWRDQNQLCSSGYKRCLHPEF*HCGARE
AGGQHREDGWRDRWPPHVHHHSPGRDAHHQKEK
KCLFLLLLLVPKEAGQEAEGDPEWSPEGDGACGL
CRQTHHQAQRQPQ**RLLF*FSGRQRIHRWQPR
GAFPAHPHDPDSSLPHL*PCGDELPPGPVPTRH
PGG*LAAAHHADEERPGLRVQGGIRGLTRGADSF
VGHSQGG*KPQ*ESIWEHHILRPFPGEAAGAGW
RPAL*LHQCQLH*RIPSTSALHCDSRSDAGDCK
GLLENDLAGELRQHRHGHKPGGSGQGEMCAILAR
*HGGLRRH*SHPD*NRAPGRIRHTHLHSPEERL
P*DPGAPPLPLHQLA*PRRSLLCHWPSGLRPPG
QVPQPPGSWAHSGPLQCWGWADWLLHCH*HHA*H
GRE*RGGGHLQLRA*APGPKGQPGTDRGAICVC
ARCHPGSVPLWQHCHPCV*VPFSLLQYQQAGPP
DKLQPNQR*ISDPQHCDTPCAARGLQHWAPAPEP
**ESKYGRAASGPLPALPYLSGRRIQQLHQRST
DG*PQAACRLRGHPAPSTQHRGRLLEAGVRLQL
LLCGDAE*DGHCPVLYAVLA*EDLRVLWAHPGGV
RLRRHRRGHHPQNIPHL*HGPATGWLSYSPAPP
VHWLACLPGHAPLQALSAQSGPTTGEVAGAV*R
EGGTYCGPLPKWGRP*WNLLCHLQCV*DDPAAKH
H*RVPHRENTA*QQIQHGGDPGTV*ICIRGGTG
IFKLLLAQWDGEPAGVQRLL*PSPLLCEWQ*LG
SGALRWHPA*LQGEDWWPCVPRGALHLLRGLLLP
WEMLLQKAQASFST*PATAKGPSRSTPTSKALD
FWLPDHLLLF*VCGSLGKPTVQVLGSGRLPCPP
SP*EWRRCVFCSSTSWKRLRLLGVTALLPPATSF
RGLWHQTFAVWTSVTLRCSLGHKRGPPSSHLTC
MGLRPQPFCTPSPAWALTVQHSLAGQLCPQQFL
IKVFFAFLCGQWEGVELQGTSLLLLVFVKRDHLP
GAGLGLTCRM*PLCFFGGSFLWKRQTR*DLIIF
QSVCEKKLSFGGCKILVSYVKKKGAGEFEYVPL
RQISRAFYFFLAMSLKAPTLGQHATEQGEMGEPE
DGPFGFWGK*STSFVHNLDVQI*TPS*RNPAAT
LKKAIVEPIIL*FKIGQENQAWRSRVLSKV*VS
Q*EGTNIC*VSTVCQGSCLALSIGHFTQSLEPPG
ESY*LVIISI*SSPPMRKPTHLP***NPGFQRG
R*WQ*DFSVLFSSSSLSQAIILWRENKARNF*A
DNSTNGNLVLSS*CQFFWEAQNFRYILVTHSQLP
RKASLI*FLSQ*KQFPVPSGYEWTSQGNSRP*S
LASA*AQYLTASGGLGPRKLHLEGWSSPRQGMR
GREFKKVQLWPSRAHCMLGKWNHGAVVWSG*VFH
EPRSKKVSSASGFLEKGTSIPAGS*QA*KGKKG
NSGKGIHMCNGKEM*KGIGRSSLGEASPVRAQH
NTGSSKR*ARVQETDAHREYRLCPIGNKESMEL*
RDALSFVLAKTPSGPMGLPLFLSSDTVKTFP*A
CTF*YHIYLSVCSLFCCWN*ICNGS*DSDSMRN
PGSLLYHGAGSPTQISRPMRMEHERSRQKLLPLA
WALELSRSPGTPDLIKEGLSL*RFKRKCLKAKA
SKGTPR*TCSFPLMSLSPGVFQQTPGTHPHWAC
WPPSAPAQCPSWPSPACKEPVAWQICLLYAIFLD
LGTSRQDEGGGRAI*HKS*DFFLLRKG*NSWQI
QKTVAFIILNGRNLRCDFREKQTCKKKKSQAML
G*PSKGQ**FPPAHPLIFPQPNHSLKQDSE*VLG
QCTQEEIEAYGWG*LP*DPMGQGCGKAWMRWGT
SAQEFEHFPLPRKSPEPTPPPPGGLPTPPHLQG
ELSLS*AEENIINAL*VFTTGALTS*MWALFGED
ARK**EAQEISPPVFMA*IASGCILAALQHCIL
SGVKNLGQPGVLGPLEGHSRPLFVGMEGDSLLL
VLALSVGVACKGTNRPYAGDSNM*AH*ILPAF*R
RVCDCHHLLMRKLRLLGEKSLAHSSTASE*MNQ
DLNRFFLTTETIFFHHCISHFSQEVTHNRRD*S
GTDTSVDKAQSKQQ*A*NSFIVSCFTFTIHAKFA
FHFLI*PCWF*YDSMNISKKNVLCSSCCSVLFT
PL*RTLGQLVFSLTLELTLGAVTLLPPRASYRL
KIKTN*PSPRQLLWCVGALTSLFMRGPQLRHLPV
GCWKEPINSH*NDEDLLIWRGEG*AHKTLKGKE
KLDTAVLSRFLNARLESGACCPSGVTWLLMWAS
LRTHFMSSWGLEGSSLYPSHT*LLGAYST*HLGG
GTIRKSRLLWHN*FLGKAWGCGGQSSVFSLNEN
IHT*KTYMKKGPSSTLEGVDLEHFRQENRNARP
GNWNPVNTQNRGCR*LI*QNGHFCDIAGERMGNS
LPEPLGTRANLSVWGKR*CISL*PIMFIHPPLP
IATLALAVSPHQDLHFLVAGGNPLEYIEVSVQ*
DCSTQQK*GPGSSSQALILLPLQE*LPNPDPETL
KEMIIPWYLTALGQNEESHPSLGCSLPLLGWVN
RSSAPSSTRSNTLEDMGEPKRKHEQDAVPKSCQ
QVVLGQDPQGKKWSTQLEGRLEEKKHKRG*SCHL
KSLTWLPHYLTV*APS*PVTSFKSQPSKTRK*E
K*IQLEETS*DSDLFTPPMQSFPVGGFPCIHV*
K**NARPWLCLAGICL*GHRLNSRERG*WWSVGG
AVLAPVSSDTFFRIMDLILRSTAEISKPYLCT*
ADSSSFLVTRDGLLHGTDYRDVL*RSSQSFASH
LPTSRRDGKRSSKGIHQLKSTHEC*VSKRRHQHS
QW*PPNLASHLSKSSGVVHWGRYKGSARAQDER
KSIGKSFRGLIIMGLPSISENCSGW*DVDSDP*
LECSENECLVALKCWTEKYQYKSLELRVINVVHG
SLVSRTLGCGGERVIGSKPPKLQN*VSVQLLQC
LWAYEYKSVGLLYDGPTNSQCPPCPCISHGR*I
MSGVLWVKGPRAVWRLRGQSGVIPCKVRLLRGQA
EYGVHIFHSSADSWMKSSTVC*TQVTPLSITRT
HE*NLIAVRKNLLSAREDKLPISAAV*KKAGVS
LKGREALVKWISGHFHSRWVRSCGAGIMFELIHT
CRARIQVDCVWSVQAEAPCSPTQVPPLSRPTCC
CGHIYWADPGWLSPNSKP*GTAALP*TQYPCRS
LMRAAITQTH*PTGP*VTARTSEGPSRTQSRAFL
TIHIISRGYFYPTPYSRPVGAHCKSKSTVTQFT
HDYNHFQCTHFITRWILS*PM*IRVNPYW*SYS
KALFTLHSTSQSKTKSCGLYHCLGFWTPSQAIPR
FPLNSREADIFTSTGHIILHETKVSTLFAASSM
NPNGLHLYSLGV**IKHV*EEKTK*INFLKKPA
LCCQCFFFLFNSSSEKQKVNNVRSMNIRYIF*LY
ITVKCNLFTPASPSYLFL*MFPDNVCNMAVLKN
LYNKAVTLRFMFS*D

Frame 1

LPPQFAPRLGLERRSAGSGSPSGASRAHSQRPR
RRCGATPRPPQSRPRPPREGAELPAAARMASLA
ALALSLLLRLQLPPLPGARAQSAAGGCSFDEHYS
NCGYSVALGTNGFTWEQINTWEKPMLDQAVPTG
SFMMVNSSGRASGQKAHLLLPTLKENDTHCIDF
HYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVS
GVVTEGWVKAELAISTFWPHFYQVIFESVSLKG
HPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNV
GQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMV
TRVVNHRRFSATVSVADTAQRSVSKYRCVIRSD
GGSGVSNYAELIVKEPPTPIAPPELLAVGATYL
WIKPNANSIIGDGPIILKEVEYRTTTGTWAETHI
VDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGP
PGPPLTTRTKCADPVHGPQNVEIVDIRARQLTL
QWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEE
VIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRME
SEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQ
WKPPNETNGVITLYEINYKAVGSLDPSADLSSQR
GKVFKLRNETHHLFVGLYPGTTYSFTIKASTAK
GFGPPVTTRIATKISAPSMPEYDTDTPLNETDT
TITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRA
ADIIECFSVPVSYRNASSLDSLHYFAAELKPAN
LPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYF
QALSKANGETKINCVRLATKGASTQNSNTVEPEK
QVDNTVKMAGVIAGLLMFIIILLGVMLTIKRRR
NAYSYSYYLSQRKLAKKQKETQSGAQREMGPVA
SADKPTTKLSASRNDEGFSSSSQDVNGFTDGSRG
ELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAI
RVADLLQHITQMKRGQGYGFKEEYEALPEGQTA
SWDTAKEDENRNKNRYGNIISYDHSRVRLLVLDG
DPHSDYINANYIDGYHRPRHYIATQGPMQETVK
DFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP
DDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGY
HEIRELRLFHFTSWPDHGVPCYATGLLGFVRQV
KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLD
MAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFV
HDAILEACLCGNTAIPVCEFRSLYYNISRLDPQ
TNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRN
HDKNRSMDVLPLDRCLPFLISVDGESSNYINAAL
MDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNC
SSVVMLNEMDTAQFCMQYWPEKTSGCYGPIQVE
FVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQ
YIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDG
REGRTVVHCLNGGGRSGTFCAICSVCEMIQQQN
IIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALE
YLSSF*LNGMGNLPESRGCCDQAPFCVNGSNWA
QEL*GGTLPDSKEKTGGPVFHGGLCTF*GVSCC
RGRCCSKRPRLPFQPNQPQPRAQAEVHPQARPWI
SGSQTTCFCSEFVDLLASQLCRCWGVGGSPALL
LLRSGGDVCSAPLRHGKD*GSWGSLLCCPLQPP
SGASGTRHLQSGPV*PYDVP*ATREAPHPHT*PA
WGFAHNHSVPLPQPGP*PSSIHWPASCVHSSF*
*RCSLLFCVVSGRGWNCRELLCSSLSL*KGTTS
LGQGLG*PVGCNPCVSLVVAFFGRDKQDKI*LFS
KVYVKRNFLLEGVKS*SLMSKRRGRGSLSMYL*
DKSLGPFIFSWQCP*KLPPWDSMPLSKERWVSL
KMVPLVSGANRAPALCIIWMSKFELLPKETQQPP
*KRPLWSPLYFDLK*AKRIRPGDLGSCPKCE*V
NEREPTFAKSLLYARDHAWHFP*DISHSP*NPQ
ERATDLLSSPFDHLLQ*GNPRTFLSNEILGSKGA
GNGNETSPCCFLHLL*AKQLFYGGKIRPETSEQ
ITPQMEI*YFLPDASSSGKRRISDIF**HIPSS
PGKPVSSNFLVSKNNSLFLQAMNGPARETLDLDL
*PVLRPNI*QPQVGWDLGSSILKAGLAPDRA*G
AENSRRYSFGPQEPTVCWGNGTMVQ*CGVDECS
MSLGARKSLRPRASWRRGRPFLLGLNKHKKEKKE
TQAKGSICAMAKKCEKALGEAVWGRPAQCGHST
TRGAARDEPGSRRQMPIASTDFVLLATRSPWSF
REMHSASCWPRLLLGQWGCLFSFHQTL*KHSLKR
ALFNITSICLSAHCFVAGTKYAMDHETQIL*ET
QGLCFTTEQGHQPRSPGP*GWNMKGADKSCFHW
HGLWSCPEVQGHQT*SRKGCHFRGSKGSASKQRQ
AKEPHDELALFL**ASPQVYFSRPRGPTPTGPA
GLPRLQPNAPAGLPQPARSL*HGKSACCMLFS*
ILVHPDRMRVEGELFNTNPKIFFCSGRGEIAGRY
KRQWLLSF*MVGI*GVTSGRNKLAKKKNLRPCW
GNPARASDDFPQLIPLFSHNPTIL*SRTVNRS*
ASAHRKKLRLMDGDDFPKIPWDKDVARLG*DGAP
VPRNLNIFLYPGNLRSQHHHPQGVSPPHPIYRV
SSACHEQRKILLMLSESLQQELLPHRCGLCLGK
MQGSNEKPRKFLHLCLWPK*LQDVS*LHSNIASF
LG*RIWANQGSLGL*KATVGLSLWEWKGTVCF*
CWPSLWVWPAKEPTDPMLGTLTCELIKFFQHSK
GGFVIVTIY**GN*GS*GRNHLPTVPQLVSE*TR
I*TGFFSLQRQYFSTIVSHIFPRRLPITEETRV
EQIRQWIKLKANNSKLKIPS*SHVLRSQFMQNL
HSTF*FSLVGFNMTL*IFQKKMCSVPHVVLFCSP
RYDGP*VSWSSA*P*N*L*EQ*PCCLPEPVIGS
RSRPTDLLLGSSFGVWVL*PHCS*GDLN*GIFQ
LGAGRNPLTHTRMMRICSSGVEKDEPTKP*REKR
SWTQLYSADS*MLGWKVVPVVQVESHGC*CGQV
*GHTS*AAGVWKAPHFTLATHNYWVPTAPSTLE
GALLGNRDYYGTINSWVRHGVVVDRAQSLV*TKT
YIHEKHT*KKDPHQH*KG*IWSTLGRKTGTQGQ
ETGTQ*ILRTEDADDLFSKMVTSVT*LEKGWVT
ACQSHLEQGQISVSGAKDDAFPSDPSCLFILHSP
LPH*LLL*VLTRIYISSSLVGTP*ST*RYQSSK
TALHNRSEAQGVAARPLSCYLCRSDCPTQIQRH
*RK**FLGTSLPWDKMKKATLP*AAACHSWAG*T
GHQHQAQPGVTLWKTWVSPRGSMNRTLFLSHVN
RLCWARIPREKNGQPNWRVG*KKKNINVDSHVI
SNP*LGFPIT*QSELLLSL*PASNHSQVKQGNRK
SKSN*KRQAEIQICLLLPCKVSLLEVFHVYMSR
SDRMQGLGFVLQGSAFEVID*TAGREVSGGVWG
ELF*LQFLLTHFSGSWI*SSEAQQRYLSHICAHE
QTLLVF**PGMGFCMALTIEMSCRDQASLLHPT
CPPPEEMGKGHQRAFTN*NPLMNVRSLKGGINT
HNGSLQT*HPTYLRAQGWSTGADTREVQGLRMKE
NLLGRVLGA*SLWGFLLYLRTALGGEMWTLILN
WNVRRMSVWWP*SVGQKSISIKAWSSG*LM*FM
VP**AGLLDVEEKGS*EVNHQNYKIESLYNYFSA
FGLMNTNQWAFSMMVQQTLSVHPVPVSPMEDE*
CQVFFGSKAPGQSGGLEGRVVSFHVKLGF*GVR
QNMVSISSIALQILG*SQAQFARPRSLL*V*LGP
MSET**L*GRTCCLPERISCPSQQLSKRRQVSL
*REEKHW*NGFQVTSIPDG*DLVELGSCLNSFI
PVEHESK*IVFGLYRLKPPALPPKCPH*AGQHAV
VATYTGLIQAGYHQTANHREQLLCHRPNTHVDL
S*EQP*LRPTDQQGHE*QPEPVKVQVGHRAGLF
LPYTLSPEVISTPLPIQGLLEHTAKAKAQ*LNLH
MIIIISSAHISSPGGS*ASPCKSGLTHIGNHTQ
KHFSPYILLANQRQRVVASTIALASGHPHKLSQ
GSRSTPGRLTSSHPLGI*YCMRPKSPHSLQPPP*
IPMACTCTVWVFDR*STYEKRKQNKSTF*KSQH
CAVNVFFFFSILAQKSRR*IMSGQ*ISDIFFDC
TLQ*SVIFLHLQVHLIYSCKCSLTMFVTWLC*KI
YTIKL*P*DSCFPKI

Frame 2

SRLSSRRASAWNAGAPAPGARAEPAARTASGRA
GDAGPPRARPSPGPGPRGKGLSCPPPPGWRASP
RSPSACS*GCSCRHCPAPGLRAPQVAVPLMSTT
ATVVIVWL*GPMGSPGSRLTHGRNQCWTRQCPQD
LS*W*TALGEPLARRPTFSCQP*RRMTPTASTS
ITTSPAVTGPAQGP*TST*R*MVAPKGTLCGMC
PGSSLRAG*RQSSPSALSGHISIR*YLNPSH*RV
ILATSPWTRSGSLLIHAEKHLIFCDSKTWR*MW
GRMPHFSALLVGSGLSMTSFGSSNGMAGTRP*W
SPVWSTTGASQPQSVWQTLPSGASASTAV*SALM
VGLVCPTTRS*S*KSLPRPLLPQSCWLWGPHTC
GSSQMPTPSSGMAPSS*RKWNIAPPQARGQRPT
*STLPTISCGIWTPMLSMRSECSSHDQVRGVRDR
QGLPSPPGPSVQIRYMAHRTWKS*TSEPGS*PC
SGSPSATR*PAAIATTSPCSTSMCSTSSSTRPR
RSSRPPPTTPCEACAPS*PSGCDSCCLTPRAEWR
ARSWWCRLRKTFQELFL*NPSKGGPLRRRSTSS
GNLPMRPMGSSRSTRSTTRLSARWTQVLTSRAR
GGKCSSSGMKPTTSLWVCTQGPPIPSPSRPAQQR
ALGPLSPLGLPPKFQLHPCLSTTQTPH*MRQTR
PSQ*C*NPLSPGELLSVFISWLSRRSDFRSHGG
QLTLLSAFRCP*AIGMPPASILYTTLLLS*SLPT
CLSPSHLQWVTIRHTMATGTLLSLP*KATASTS
RHSAKPMERPKSTVFVWLQKVPPPRILTLWSQR
SRWTTP*RWLA*SLASSCSSSFSWA*CSPSKGEE
MLIPTPITCPKGSWPRSRRRPRVEPRGRWGLWP
LPTNPPPSSAPAAMMKASLLVLRTSTDSQMAAA
GSFPSPPSRSRLIPTAPVTLWR*ATPGTSSNPPS
GWLTCCSTSRR*REARATGSRRNTRPYQRGRQL
RGTQPRRMKTAIRIDMGTSYPTTIPG*GCWCWM
ETRTLTTSMPTTLTDTIDLGTTLRLKVRCRRL*R
TFGE*SGRRTPPASSWSQTWWKWAG*NVCDTGQ
MTRRSTETLKSP*LKQSPWQNTSYAPSQSRRKA
TMRSGSSASSTSPAGLTTAFPAMPLAFWASSARS
SSSTPRKLGP*WSTAVLGLGGLAASLPLTPCLT
WPRMKGWWTSSTACVSSGPKGSTWYRQRSNMCL
CTMPSWKRASVATLPSLCVSSVLSTTISAGWTPR
QTPAKSKMNFRPSTL*HPVCGPRTAALGSCPGT
MIRIEVWTCCLWTAACPSLSQWTENPAITSTQH
*WIATSSLPPSWSPSTLYPTPWQTSGGWCSITTA
PLW*C*MRWTLPSSVCSTGLRRPPGAMGPSRWS
SSPQTSTRTSSTEYSASVTWPGHRMVIV*SSTS
STLAGLPTGTRPPPSALCSKWSDDWRSGRSSMTG
GRDVLWSTA*MGEAVVEPSVPSAVCVR*SSSKT
SLTCSTS*KHCVTTNPTWWRPWNSINLYTRWHW
NI*APFSSMGWGTCRSPEAAVTKPPFV*MAVTGL
RSSEVAPCLTPRRRLVALCSTGGSAPSEGSPVA
VGDAAPKGPGFLFNLTSHSQGPKQKYTHKQGLG
FLAPRPPAFVLSLWISWQANCAGAGEWEAPLPSF
SLGVEEMCVLLLYVMEKIEALGGHCSAAPCNLL
QGPLAPDICSLDQCDLTMFPRPQERPPILTPNL
HGASPTTILYPFPSLGLDRPAFTGRPAVSTAVFD
KGVLCFFVWSVGGGGTAGNFSAPPCLCKKGPPP
WGRAWADL*DVTPVFLWW*LSLEETNKIRFDYF
PKCM*KETFFWRV*NLSLLCQKEGGGGV*VCTSK
TNLSGLLFFPGNVLKSSHPGTACH*ARRDG*A*
RWSLWFLGQIEHQLCA*FGCPNLNSFLKKPSSH
LEKGHCGAHYTLI*NRPRESGLEI*GLVQSVSES
MRGNQHLLSLYCMPGIMLGTFHRTFHTVLRTPR
RELLTCYHLHLIISSNEETHAPSLVMKSWVPKG
QVMAMRLLRAVFFIFSKPSNYFMEGK*GQKLLSR
*LHKWKFSTFFLMPVLLGSAEFQIYFSNTFPAP
QESQSHLIS*SVKTIPCSFRL*MDQPGKLSTLI
SSQCLGPISDSLRWAGT*EAPS*RLV*PQTGHEG
QRIQEGTALALKSPLYAGEMEPWCSSVEWMSVP
*A*EQESLFGLGLPGEGDVHSCWVLTSIKRKKR
KLRQRDPYVQWQRNVKRHWEKQSGGGQPSAGTAQ
HGEQQEMSQGPGDRCPSRVQTLSYWQQGVHGAL
ERCTQLRVGQDSFWANGAASFPFIRHCENIPLS
VHFLISHLFVCLLIVLLLELNMQWIMRLRFYEKP
RVSALPRSRVTNPDLQAHEDGT*KEPTKVASIG
MGSGAVQKSRDTRLDQGRAVTLEVQKEVPQSKG
KQRNPTMNLLFSFDEPLPRCISADPGDPPPLGLL
ASLGSSPMPQLAFPSLQGACSMANLPAVCYFLR
SWYIQTG*GWRESYLTQILRFFSAQEGVK*LAD
TKDSGFYHFKW*EFKV*LQGETNLQKKKISGHVG
VTQQGPVMISPSSSPYFPTTQPFSKAGQ*IGLR
PVHTGRN*GLWMGMTSLRSHGTRMWQGLDEMGH
QCPGI*TFSFTQEISGANTTTPRGSPHPTPFTG*
AQPVMSRGKYY*CSLSLYNRSSYLIDVGSVWGR
CKEVMRSPGNFSTCVYGLNSFRMYLSCTPTLHP
FWGEESGPTRGPWASRRPQ*ASLCGNGRGQFAFS
AGPLCGCGLQRNQQTLCWGL*HVSSLNSSSILK
EGL*LSPFTDEETKAPRGEITCPQFHS**VNEP
GFKPVFSHYRDNIFPPLYLTFFPGGYP*QKRLEW
NRYVSG*SSKQTTVSLKFLHSLMFYVHNSCKIC
IPLSDLALLVLI*LYEYFKKKCALFLMLFCSVH
PAMTDPRSAGLQLDPRIDSRSSDPAASQSQL*AQ
DQDQLTFS*AAPLVCGCSDLTVHEGTSTKASSS
WVLEGTH*LTLE**GFAHLAWRRMSPQNPKGKR
EAGHSCTQQIPEC*AGKWCLLSKWSHMVANVGKS
EDTLHEQLGSGRLLTLP*PHIITGCLQHLAPWR
GHY*EIEITMAQLIPG*GMGLWWTELSL*FERK
HTYMKNIHEKRTLINIRRGRFGAL*AGKQERKAR
KLEPSEYSEPRMQMTYLAKWSLL*HSWRKDG*Q
LARATWNKGKSQCLGQKMMHFPLTHHVYSSSTP
HCHTSSCCKSSPGSTFPRRWWEPLRVHRGISPVR
LLYTTEVRPRE*QPGPYPVTSAGVTAQPRSRDI
EGNDNSLVPHCLGTK*RKPPFLRLQLATPGLGK
QVISTKLNQE*HSGRHG*AQEEA*TGRCS*VMST
GCAGPGSPGKKMVNPTGG*VRRKKT*TWIVMSS
QIPDLASPLLNSLSSFLACDQLQITAK*NKEIG
KVNPTRRDKLRFRFVYSSHAKFPCWRFSMYTCLE
VIECKALALSCRDLPLRS*TEQQGERLVVECGG
SCSSSSFF*HIFQDHGSDPPKHSRDI*AIFVHM
SRLF*FFSNQGWAFAWH*L*RCLVEIKPVFCIPP
AHLQKRWEKVIKGHSPTEIHS*MLGL*KEASTL
TMVASKPSIPPI*ELRGGPLGQIQGKCKGSG*K
KIYWEEF*GLDHYGASFYI*ELLWVVRCGL*SLI
GMFGE*VSGGLEVLDRKVSV*KPGAQGN*CSSW
FLSEQDSWMWRRKGHRK*TTKITKLSLCTITSV
PLGL*IQISGPSL*WSNKLSVSTLSLYLPWKMNN
VRCSLGQRPQGSLEA*RAEWCHSM*S*ASEGSG
RIWCPYLP*LCRFLDEVKHSLLDPGHSSEYN*D
P*VKLNSCKEEPAVCQRG*AAHLSSCLKEGRCLF
KGKRSIGEMDFRSLPFQMGEILWSWDHV*THSY
L*STNPSRLCLVCTG*SPLLSHPSAPTEQANML
LWPHILG*SRLVITKQQTIGNSCFAIDPIPM*IS
HESSHNSDPLTNRAMSDSQNQ*RSK*DTEQGFS
YHTHYLQRLFLPHSLFKACWSTLQKQKHSNSIY
T*L*SFPVHTFHHQVDPELAHVNPG*PILVIILK
STFHPTFY*PIKDKELWPLPLPWLLDTLTSYPK
VPAQLQGG*HLHIHWAYNIA*DQSLHTLCSLLH
ESQWPALVQFGCLIDKARMRRENKINQLFKKAST
VLSMFFFSFQF*LRKAEGK*CQVNEYQIYFLTV
HYSEV*SFYTCKSILFILVNVP*QCL*HGCVKK
SIQ*SCDPEIHVFLR

Sequence NM_133170

CCTCCCGCCTCAGTTCGCGCCGCGCCTCGGCTTGGAACGCAGGAGCGCCGGCTCCGGGAGCCCGAGCGGAGCCAGCCGCGCGCACAGCCAGCGGCCGCGC
CGGCGATGCGGGGCCACCCCGCGCCCGCCCCAGTCCCGGCCCCGGCCCCCGCGGGAAGGGGCTGAGCTGCCCGCCGCCGCCCGGATGGCGAGCCTCGCCG
CGCTCGCCCTCAGCCTGCTCCTGAGGCTGCAGCTGCCGCCACTGCCCGGCGCCCGGGCTCAGAGCGCCGCAGGTGGCTGTTCCTTTGATGAGCACTACAG
CAACTGTGGTTATAGTGTGGCTCTAGGGACCAATGGGTTCACCTGGGAGCAGATTAACACATGGGAGAAACCAATGCTGGACCAGGCAGTGCCCACAGGA
TCTTTCATGATGGTGAACAGCTCTGGGAGAGCCTCTGGCCAGAAGGCCCACCTTCTCCTGCCAACCCTGAAGGAGAATGACACCCACTGCATCGACTTCC
ATTACTACTTCTCCAGCCGTGACAGGTCCAGCCCAGGGGCCTTGAACGTCTACGTGAAGGTGAATGGTGGCCCCCAAGGGAACCCTGTGTGGAATGTGTC
CGGGGTCGTCACTGAGGGCTGGGTGAAGGCAGAGCTCGCCATCAGCACTTTCTGGCCACATTTCTATCAGGTGATATTTGAATCCGTCTCATTGAAGGGT
CATCCTGGCTACATCGCCGTGGACGAGGTCCGGGTCCTTGCTCATCCATGCAGAAAAGCACCTCATTTTCTGCGACTCCAAAACGTGGAGGTGAATGTGG
GGCAGAATGCCACATTTCAGTGCATTGCTGGTGGGAAGTGGTCTCAGCATGACAAGCTTTGGCTCCAGCAATGGAATGGCAGGGACACGGCCCTGATGGT
CACCCGTGTGGTCAACCACAGGCGCTTCTCAGCCACAGTCAGTGTGGCAGACACTGCCCAGCGGAGCGTCAGCAAGTACCGCTGTGTGATCCGCTCTGAT
GGTGGGTCTGGTGTGTCCAACTACGCGGAGCTGATCGTGAAAGAGCCTCCCACGCCCATTGCTCCCCCAGAGCTGCTGGCTGTGGGGGCCACATACCTGT
GGATCAAGCCAAATGCCAACTCCATCATCGGGGATGGCCCCATCATCCTGAAGGAAGTGGAATATCGCACCACCACAGGCACGTGGGCAGAGACCCACAT
AGTCGACTCTCCCAACTATAAGCTGTGGCATCTGGACCCCGATGTTGAGTATGAGATCCGAGTGCTCCTCACACGACCAGGTGAGGGGGGTACGGGACCG
CCAGGGCCTCCCCTCACCACCAGGACCAAGTGTGCAGATCCGGTACATGGCCCACAGAACGTGGAAATCGTAGACATCAGAGCCCGGCAGCTGACCCTGC
AGTGGGAGCCCTTCGGCTACGCGGTGACCCGCTGCCATAGCTACAACCTCACCGTGCAGTACCAGTATGTGTTCAACCAGCAGCAGTACGAGGCCGAGGA
GGTCATCCAGACCTCCTCCCACTACACCCTGCGAGGCCTGCGCCCCTTCATGACCATCCGGCTGCGACTCTTGCTGTCTAACCCCGAGGGCCGAATGGAG
AGCGAGGAGCTGGTGGTGCAGACTGAGGAAGACGTTCCAGGAGCTGTTCCTCTAGAATCCATCCAAGGGGGGCCCTTTGAGGAGAAGATCTACATCCAGT
GGAAACCTCCCAATGAGACCAATGGGGTCATCACGCTCTACGAGATCAACTACAAGGCTGTCGGCTCGCTGGACCCAAGTGCTGACCTCTCGAGCCAGAG
GGGGAAAGTGTTCAAGCTCCGGAATGAAACCCACCACCTCTTTGTGGGTCTGTACCCAGGGACCACCTATTCCTTCACCATCAAGGCCAGCACAGCAAAG
GGCTTTGGGCCCCCTGTCACCACTCGGATTGCCACCAAAATTTCAGCTCCATCCATGCCTGAGTACGACACAGACACCCCATTGAATGAGACAGACACGA
CCATCACAGTGATGCTGAAACCCGCTCAGTCCCGGGGAGCTCCTGTCAGTGTTTATCAGCTGGTTGTCAAGGAGGAGCGACTTCAGAAGTCACGGAGGGC
AGCTGACATTATTGAGTGCTTTTCGGTGCCCGTGAGCTATCGGAATGCCTCCAGCCTCGATTCTCTACACTACTTTGCTGCTGAGTTGAAGCCTGCCAAC
CTGCCTGTCACCCAGCCATTTACAGTGGGTGACAATAAGACATACAATGGCTACTGGAACCCTCCTCTCTCTCCCCTGAAAAGCTACAGCATCTACTTCC
AGGCACTCAGCAAAGCCAATGGAGAGACCAAAATCAACTGTGTTCGTCTGGCTACAAAAGCACCAATGGGCAGCGCCCAGGTGACCCCGGGGACTCCACT
CTGCCTCCTCACCACAG
GTGCCTCCACCCAGAATTCTAACACTGTGGAGCCAGAGAAGCAGGTGGACAACACCGTGAAGATGGCTGGCGTGATCGCTGGC
CTCCTCATGTTCATCATCATTCTCCTGGGCGTGATGCTCACCATCAAAAGGAGAAGAAATGCTTATTCCTACTCCTATTACTTGTCCCAAAGGAAGCTGG
CCAAGAAGCAGAAGGAGACCCAGAGTGGAGCCCAGAGGGAGATGGGGCCTGTGGCCTCTGCCGACAAACCCACCACCAAGCTCAGCGCCAGCCGCAATGA
TGAAGGCTTCTCTTCTAGTTCTCAGGACGTCAACGGATTCACAGATGGCAGCCGCGGGGAGCTTTCCCAGCCCACCCTCACGATCCAGACTCATCCCTAC
CGCACCTGTGACCCTGTGGAGATGAGCTACCCCCGGGACCAGTTCCAACCCGCCATCCGGGTGGCTGACTTGCTGCAGCACATCACGCAGATGAAGAGAG
GCCAGGGCTACGGGTTCAAGGAGGAATACGAGGCCTTACCAGAGGGGCAGACAGCTTCGTGGGACACAGCCAAGGAGGATGAAAACCGCAATAAGAATCG
ATATGGGAACATCATATCCTACGACCATTCCCGGGTGAGGCTGCTGGTGCTGGATGGAGACCCGCACTCTGACTACATCAATGCCAACTACATTGACGGA
TACCATCGACCTCGGCACTACATTGCGACTCAAGGTCCGATGCAGGAGACTGTAAAGGACTTTTGGAGAATGATCTGGCAGGAGAACTCCGCCAGCATCG
TCATGGTCACAAACCTGGTGGAAGTGGGCAGGGTGAAATGTGTGCGATACTGGCCAGATGACACGGAGGTCTACGGAGACATTAAAGTCACCCTGATTGA
AACAGAGCCCCTGGCAGAATACGTCATACGCACCTTCACAGTCCAGAAGAAAGGCTACCATGAGATCCGGGAGCTCCGCCTCTTCCACTTCACCAGCTGG
CCTGACCACGGCGTTCCCTGCTATGCCACTGGCCTTCTGGGCTTCGTCCGCCAGGTCAAGTTCCTCAACCCCCCGGAAGCTGGGCCCATAGTGGTCCACT
GCAGTGCTGGGGCTGGGCGGACTGGCTGCTTCATTGCCATTGACACCATGCTTGACATGGCCGAGAATGAAGGGGTGGTGGACATCTTCAACTGCGTGCG
TGAGCTCCGGGCCCAAAGGGTCAACCTGGTACAGACAGAGGAGCAATATGTGTTTGTGCACGATGCCATCCTGGAAGCGTGCCTCTGTGGCAACACTGCC
ATCCCTGTGTGTGAGTTCCGTTCTCTCTACTACAATATCAGCAGGCTGGACCCCCAGACAAACTCCAGCCAAATCAAAGATGAATTTCAGACCCTCAACA
TTGTGACACCCCGTGTGCGGCCCGAGGACTGCAGCATTGGGCTCCTGCCCCGGAACCATGATAAGAATCGAAGTATGGACGTGCTGCCTCTGGACCGCTG
CCTGCCCTTCCTTATCTCAGTGGACGGAGAATCCAGCAATTACATCAACGCAGCACTGATGGATAGCCACAAGCAGCCTGCCGCCTTCGTGGTCACCCAG
CACCCTCTACCCAACACCGTGGCAGACTTCTGGAGGCTGGTGTTCGATTACAACTGCTCCTCTGTGGTGATGCTGAATGAGATGGACACTGCCCAGTTCT
GTATGCAGTACTGGCCTGAGAAGACCTCCGGGTGCTATGGGCCCATCCAGGTGGAGTTCGTCTCCGCAGACATCGACGAGGACATCATCCACAGAATATT
CCGCATCTGTAACATGGCCCGGCCACAGGATGGTTATCGTATAGTCCAGCACCTCCAGTACATTGGCTGGCCTGCCTACCGGGACACGCCCCCCTCCAAG
CGCTCTCTGCTCAAAGTGGTCCGACGACTGGAGAAGTGGCAGGAGCAGTATGACGGGAGGGAGGGACGTACTGTGGTCCACTGCCTAAATGGGGGAGGCC
GTAGTGGAACCTTCTGTGCCATCTGCAGTGTGTGTGAGATGATCCAGCAGCAAAACATCATTGACGTGTTCCACATCGTGAAAACACTGCGTAACAACAA
ATCCAACATGGTGGAGACCCTGGAACAGTATAAATTTGTATACGAGGTGGCACTGGAATATTTAAGCTCCTTTTAGCTCAATGGGATGGGGAACCTGCCG
GAGTCCAGAGGCTGCTGTGACCAAGCCCCCTTTTGTGTGAATGGCAGTAACTGGGCTCAGGAGCTCTGAGGTGGCACCCTGCCTGACTCCAAGGAGAAGA
CTGGTGGCCCTGTGTTCCACGGGGGGCTCTGCACCTTCTGAGGGGTCTCCTGTTGCCGTGGGAGATGCTGCTCCAAAAGGCCCAGGCTTCCTTTTCAACC
TAACCAGCCACAGCCAAGGGCCCAAGCAGAAGTACACCCACAAGCAAGGCCTTGGATTTCTGGCTCCCAGACCACCTGCTTTTGTTCTGAGTTTGTGGAT
CTCTTGGCAAGCCAACTGTGCAGGTGCTGGGGAGTGGGAGGCTCCCCTGCCCTCCTTCTCCTTAGGAGTGGAGGAGATGTGTGTTCTGCTCCTCTACGTC
ATGGAAAAGATTGAGGCTCTTGGGGGTCACTGCTCTGCTGCCCCCTGCAACCTCCTTCAGGGGCCTCTGGCACCAGACATTTGCAGTCTGGACCAGTGTG
ACCTTACGATGTTCCCTAGGCCACAAGAGAGGCCCCCCATCCTCACACCTAACCTGCATGGGGCTTCGCCCACAACCATTCTGTACCCCTTCCCCAGCCT
GGGCCTTGACCGTCCAGCATTCACTGGCCGGCCAGCTGTGTCCACAGCAGTTTTTGATAAAGGTGTTCTTTGCTTTTTTGTGTGGTCAGTGGGAGGGGGT
GGAACTGCAGGGAACTTCTCTGCTCCTCCTTGTCTTTGTAAAAAGGGACCACCTCCCTGGGGCAGGGCTTGGGCTGACCTGTAGGATGTAACCCCTGTGT
TTCTTTGGTGGTAGCTTTCTTTGGAAGAGACAAACAAGATAAGATTTGATTATTTTCCAAAGTGTATGTGAAAAGAAACTTTCTTTTGGAGGGTGTAAAA
TCTTAGTCTCTTATGTCAAAAAGAAGGGGGCGGGGGAGTTTGAGTATGTACCTCTAAGACAAATCTCTCGGGCCTTTTATTTTTTCCTGGCAATGTCCTT
AAAAGCTCCCACCCTGGGACAGCATGCCACTGAGCAAGGAGAGATGGGTGAGCCTGAAGATGGTCCCTTTGGTTTCTGGGGCAAATAGAGCACCAGCTTT
GTGCATAATTTGGATGTCCAAATTTGAACTCCTTCCTAAAGAAACCCAGCAGCCACCTTGAAAAAGGCCATTGTGGAGCCCATTATACTTTGATTTAAAA
TAGGCCAAGAGAATCAGGCCTGGAGATCTAGGGTCTTGTCCAAAGTGTGAGTGAGTCAATGAGAGGGAACCAACATTTGCTAAGTCTCTACTGTATGCCA
GGGATCATGCTTGGCACTTTCCATAGGACATTTCACACAGTCCTTAGAACCCCCAGGAGAGAGCTACTGACTTGTTATCATCTCCATTTGATCATCTCCT
CCAATGAGGAAACCCACGCACCTTCCTTAGTAATGAAATCCTGGGTTCCAAAGGGGCAGGTAATGGCAATGAGACTTCTCCGTGCTGTTTTCTTCATCTT
CTCTAAGCCAAGCAATTATTTTATGGAGGGAAAATAAGGCCAGAAACTTCTGAGCAGATAACTCCACAAATGGAAATTTAGTACTTTCTTCCTGATGCCA
GTTCTTCTGGGAAGCGCAGAATTTCAGATATATTTTAGTAACACATTCCCAGCTCCCCAGGAAAGCCAGTCTCATCTAATTTCTTAGTCAGTAAAAACAA
TTCCCTGTTCCTTCAGGCTATGAATGGACCAGCCAGGGAAACTCTCGACCTTGATCTCTAGCCAGTGCTTAGGCCCAATATCTGACAGCCTCAGGTGGGC
TGGGACCTAGGAAGCTCCATCTTGAAGGCTGGTCTAGCCCCAGACAGGGCATGAGGGGCAGAGAATTCAAGAAGGTACAGCTTTGGCCCTCAAGAGCCCA
CTGTATGCTGGGGAAATGGAACCATGGTGCAGTAGTGTGGAGTGGATGAGTGTTCCATGAGCCTAGGAGCAAGAAAGTCTCTTCGGCCTCGGGCTTCCTG
GAGAAGGGGACGTCCATTCCTGCTGGGTCTTAACAAGCATAAAAAGGAAAAAAAGGAAACTCAGGCAAAGGGATCCATATGTGCAATGGCAAAGAAATGT
GAAAAGGCATTGGGAGAAGCAGTCTGGGGGAGGCCAGCCCAGTGCGGGCACAGCACAACACGGGGAGCAGCAAGAGATGAGCCAGGGTCCAGGAGACAGA
TGCCCATCGCGAGTACAGACTTTGTCCTATTGGCAACAAGGAGTCCATGGAGCTTTAGAGAGATGCACTCAGCTTCGTGTTGGCCAAGACTCCTTCTGGG
CCAATGGGGCTGCCTCTTTTCCTTTCATCAGACACTGTGAAAACATTCCCTTAAGCGTGCACTTTTTAATATCACATCTATTTGTCTGTCTGCTCATTGT
TTTGTTGCTGGAACTAAATATGCAATGGATCATGAGACTCAGATTCTATGAGAAACCCAGGGTCTCTGCTTTACCACGGAGCAGGGTCACCAACCCAGAT
CTCCAGGCCCATGAGGATGGAACATGAAAGGAGCCGACAAAAGTTGCTTCCATTGGCATGGGCTCTGGAGCTGTCCAGAAGTCCAGGGACACCAGACTTG
ATCAAGGAAGGGCTGTCACTTTAGAGGTTCAAAAGGAAGTGCCTCAAAGCAAAGGCAAGCAAAGGAACCCCACGATGAACTTGCTCTTTTCCTTTGATGA
GCCTCTCCCCAGGTGTATTTCAGCAGACCCCGGGGACCCACCCCCACTGGGCCTGCTGGCCTCCCTCGGCTCCAGCCCAATGCCCCAGCTGGCCTTCCCC
AGCCTGCAAGGAGCCTGTAGCATGGCAAATCTGCCTGCTGTATGCTATTTTCTTAGATCTTGGTACATCCAGACAGGATGAGGGTGGAGGGAGAGCTATT
TAACACAAATCCTAAGATTTTTTTCTGCTCAGGAAGGGGTGAAATAGCTGGCAGATACAAAAGACAGTGGCTTTTATCATTTTAAATGGTAGGAATTTAA
GGTGTGACTTCAGGGAGAAACAAACTTGCAAAAAAAAAAAATCTCAGGCCATGTTGGGGTAACCCAGCAAGGGCCAGTGATGATTTCCCCCAGCTCATCC
CCTTATTTTCCCACAACCCAACCATTCTCTAAAGCAGGACAGTGAATAGGTCTTAGGCCAGTGCACACAGGAAGAAATTGAGGCTTATGGATGGGGATGA
CTTCCCTAAGATCCCATGGGACAAGGATGTGGCAAGGCTTGGATGAGATGGGGCACCAGTGCCCAGGAATTTGAACATTTTCCTTTACCCAGGAAATCTC
CGGAGCCAACACCACCACCCCCAGGGGGTCTCCCCACCCCACCCCATTTACAGGGTGAGCTCAGCCTGTCATGAGCAGAGGAAAATATTATTAATGCTCT
CTGAGTCTTTACAACAGGAGCTCTTACCTCATAGATGTGGGCTCTGTTTGGGGAAGATGCAAGGAAGTAATGAGAAGCCCAGGAAATTTCTCCACCTGTG
TTTATGGCCTAAATAGCTTCAGGATGTATCTTAGCTGCACTCCAACATTGCATCCTTTCTGGGGTGAAGAATCTGGGCCAACCAGGGGTCCTTGGGCCTC
TAGAAGGCCACAGTAGGCCTCTCTTTGTGGGAATGGAAGGGGACAGTTTGCTTTTAGTGCTGGCCCTCTCTGTGGGTGTGGCCTGCAAAGGAACCAACAG
ACCCTATGCTGGGGACTCTAACATGTGAGCTCATTAAATTCTTCCAGCATTCTAAAGGAGGGTTTGTGATTGTCACCATTTACTGATGAGGAAACTAAGG
CTCCTAGGGGAGAAATCACTTGCCCACAGTTCCACAGCTAGTGAGTGAATGAACCAGGATTTAAACCGGTTTTTTCTCACTACAGAGACAATATTTTTCC
ACCATTGTATCTCACATTTTTCCCAGGAGGTTACCCATAACAGAAGAGACTAGAGTGGAACAGATACGTCAGTGGATAAAGCTCAAAGCAAACAACAGTA
AGCTTAAAATTCCTTCATAGTCTCATGTTTTACGTTCACAATTCATGCAAAATTTGCATTCCACTTTCTGATTTAGCCTTGTTGGTTTTAATATGACTCT
ATGAATATTTCAAAAAAAAATGTGCTCTGTTCCTCATGTTGTTCTGTTCTGTTCACCCCGCTATGACGGACCCTAGGTCAGCTGGTCTTCAGCTTGACCC
TAGAATTGACTCTAGGAGCAGTGACCCTGCTGCCTCCCAGAGCCAGTTATAGGCTCAAGATCAAGACCAACTGACCTTCTCCTAGGCAGCTCCTTTGGTG
TGTGGGTGCTCTGACCTCACTGTTCATGAGGGGACCTCAACTAAGGCATCTTCCAGTTGGGTGCTGGAAGGAACCCATTAACTCACACTAGAATGATGAG
GATTTGCTCATCTGGCGTGGAGAAGGATGAGCCCACAAAACCCTAAAGGGAAAAGAGAAGCTGGACACAGCTGTACTCAGCAGATTCCTGAATGCTAGGC
TGGAAAGTGGTGCCTGTTGTCCAAGTGGAGTCACATGGTTGCTAATGTGGGCAAGTCTGAGGACACACTTCATGAGCAGCTGGGGTCTGGAAGGCTCCTC
ACTTTACCCTAGCCACACATAATTACTGGGTGCCTACAGCACCTAGCACCTTGGAGGGGGCACTATTAGGAAATCGAGATTACTATGGCACAATTAATTC
CTGGGTAAGGCATGGGGTTGTGGTGGACAGAGCTCAGTCTTTAGTTTGAACGAAAACATACATACATGAAAAACATACATGAAAAAAGGACCCTCATCAA
CATTAGAAGGGGTAGATTTGGAGCACTTTAGGCAGGAAAACAGGAACGCAAGGCCAGGAAACTGGAACCCAGTGAATACTCAGAACCGAGGATGCAGATG
ACTTATTTAGCAAAATGGTCACTTCTGTGACATAGCTGGAGAAAGGATGGGTAACAGCTTGCCAGAGCCACTTGGAACAAGGGCAAATCTCAGTGTCTGG
GGCAAAAGATGATGCATTTCCCTCTGACCCATCATGTTTATTCATCCTCCACTCCCCATTGCCACACTAGCTCTTGCTGTAAGTCCTCACCAGGATCTAC
ATTTCCTCGTCGCTGGTGGGAACCCCTTAGAGTACATAGAGGTATCAGTCCAGTAAGACTGCTCTACACAACAGAAGTGAGGCCCAGGGAGTAGCAGCCA
GGCCCTTATCCTGTTACCTCTGCAGGAGTGACTGCCCAACCCAGATCCAGAGACATTGAAGGAAATGATAATTCCTTGGTACCTCACTGCCTTGGGACAA
AATGAAGAAAGCCACCCTTCCTTAGGCTGCAGCTTGCCACTCCTGGGCTGGGTAAACAGGTCATCAGCACCAAGCTCAACCAGGAGTAACACTCTGGAAG
ACATGGGTGAGCCCAAGAGGAAGCATGAACAGGACGCTGTTCCTAAGTCATGTCAACAGGTTGTGCTGGGCCAGGATCCCCAGGGAAAAAAATGGTCAAC
CCAACTGGAGGGTAGGTTAGAAGAAAAAAAACATAAACGTGGATAGTCATGTCATCTCAAATCCCTGACTTGGCTTCCCCATTACTTAACAGTCTGAGCT
CCTTCTTAGCCTGTGACCAGCTTCAAATCACAGCCAAGTAAAACAAGGAAATAGGAAAAGTAAATCCAACTAGAAGAGACAAGCTGAGATTCAGATTTGT
TTACTCCTCCCATGCAAAGTTTCCCTGTTGGAGGTTTTCCATGTATACATGTCTAGAAGTGATAGAATGCAAGGCCTTGGCTTTGTCTTGCAGGGATCTG
CCTTTGAGGTCATAGACTGAACAGCAGGGAGAGAGGTTAGTGGTGGAGTGTGGGGGGAGCTGTTCTAGCTCCAGTTTCTTCTGACACATTTTTCAGGATC
ATGGATCTGATCCTCCGAAGCACAGCAGAGATATCTAAGCCATATTTGTGCACATGAGCAGACTCTTCTAGTTTTTTAGTAACCAGGGATGGGCTTTTGC
ATGGCACTGACTATAGAGATGTCTTGTAGAGATCAAGCCAGTCTTTTGCATCCCACCTGCCCACCTCCAGAAGAGATGGGAAAAGGTCATCAAAGGGCAT
TCACCAACTGAAATCCACTCATGAATGTTAGGTCTCTAAAAGGAGGCATCAACACTCACAATGGTAGCCTCCAAACCTAGCATCCCACCTATCTAAGAGC
TCAGGGGTGGTCCACTGGGGCAGATACAAGGGAAGTGCAAGGGCTCAGGATGAAAGAAAATCTATTGGGAAGAGTTTTAGGGGCTTGATCATTATGGGGC
TTCCTTCTATATCTGAGAACTGCTCTGGGTGGTGAGATGTGGACTCTGATCCTTAATTGGAATGTTCGGAGAATGAGTGTCTGGTGGCCTTGAAGTGTTG
GACAGAAAAGTATCAGTATAAAAGCCTGGAGCTCAGGGTAATTAATGTAGTTCATGGTTCCTTAGTGAGCAGGACTCTTGGATGTGGAGGAGAAAGGGTC
ATAGGAAGTAAACCACCAAAATTACAAAATTGAGTCTCTGTACAATTACTTCAGTGCCTTTGGGCTTATGAATACAAATCAGTGGGCCTTCTCTATGATG
GTCCAACAAACTCTCAGTGTCCACCCTGTCCCTGTATCTCCCATGGAAGATGAATAATGTCAGGTGTTCTTTGGGTCAAAGGCCCCAGGGCAGTCTGGAG
GCTTAGAGGGCAGAGTGGTGTCATTCCATGTAAAGTTAGGCTTCTGAGGGGTCAGGCAGAATATGGTGTCCATATCTTCCATAGCTCTGCAGATTCTTGG
ATGAAGTCAAGCACAGTTTGCTAGACCCAGGTCACTCCTCTGAGTATAACTAGGACCCATGAGTGAAACTTAATAGCTGTAAGGAAGAACCTGCTGTCTG
CCAGAGAGGATAAGCTGCCCATCTCAGCAGCTGTCTAAAAGAAGGCAGGTGTCTCTTTAAAGGGAAGAGAAGCATTGGTGAAATGGATTTCAGGTCACTT
CCATTCCAGATGGGTGAGATCTTGTGGAGCTGGGATCATGTTTGAACTCATTCATACCTGTAGAGCACGAATCCAAGTAGATTGTGTTTGGTCTGTACAG
GCTGAAGCCCCCTGCTCTCCCACCCAAGTGCCCCCACTGAGCAGGCCAACATGCTGTTGTGGCCACATATACTGGGCTGATCCAGGCTGGTTATCACCAA
ACAGCAAACCATAGGGAACAGCTGCTTTGCCATAGACCCAATACCCATGTAGATCTCTCATGAGAGCAGCCATAACTCAGACCCACTGACCAACAGGGCC
ATGAGTGACAGCCAGAACCAGTGAAGGTCCAAGTAGGACACAGAGCAGGGCTTTTCTTACCATACACATTATCTCCAGAGGTTATTTCTACCCCACTCCC
TATTCAAGGCCTGTTGGAGCACACTGCAAAAGCAAAAGCACAGTAACTCAATTTACACATGATTATAATCATTTCCAGTGCACACATTTCATCACCAGGT
GGATCCTGAGCTAGCCCATGTAAATCCGGGTTAACCCATATTGGTAATCATACTCAAAAGCACTTTTCACCCTACATTCTACTAGCCAATCAAAGACAAA
GAGTTGTGGCCTCTACCATTGCCTTGGCTTCTGGACACCCTCACAAGCTATCCCAAGGTTCCCGCTCAACTCCAGGGAGGCTGACATCTTCACATCCACT
GGGCATATAATATTGCATGAGACCAAAGTCTCCACACTCTTTGCAGCCTCCTCCATGAATCCCAATGGCCTGCACTTGTACAGTTTGGGTGTTTGATAGA
TAAAGCACGTATGAGAAGAGAAAACAAAATAAATCAACTTTTTAAAAAAGCCAGCACTGTGCTGTCAATGTTTTTTTTTTCTTTTCAATTCTAGCTCAGA
AAAGCAGAAGGTAAATAATGTCAGGTCAATGAATATCAGATATATTTTTTGACTGTACATTACAGTGAAGTGTAATCTTTTTACACCTGCAAGTCCATCT
TATTTATTCTTGTAAATGTTCCCTGACAATGTTTGTAACATGGCTGTGTTAAAAAATCTATACAATAAAGCTGTGACCCTGAGATTCATGTTTTCCTAAG
ATA
  • refseq_PTPRT.F1 (forward primer)
  • refseq_PTPRT.R1 (reverse primer)
  • Single exon skipping

Frame 0

PPASVRAAPRLGTQERRLREPERSQPRAQPAAA
PAMRGHPAPAPVPAPAPAGRG*AARRRPDGEPRR
ARPQPAPEAAAAATARRPGSERRRWLFL**ALQ
QLWL*CGSRDQWVHLGAD*HMGETNAGPGSAHR
IFHDGEQLWESLWPEGPPSPANPEGE*HPLHRLP
LLLLQP*QVQPRGLERLREGEWWPPREPCVECV
RGRH*GLGEGRARHQHFLATFLSGDI*IRLIEG
SSWLHRRGRGPGPCSSMQKSTSFSATPKRGGECG
AECHISVHCWWEVVSA*QALAPAMEWQGHGPDG
HPCGQPQALLSHSQCGRHCPAERQQVPLCDPL*
WWVWCVQLRGADRERASHAHCSPRAAGCGGHIPV
DQAKCQLHHRGWPHHPEGSGISHHHRHVGRDPH
SRLSQL*AVASGPRC*V*DPSAPHTTR*GGYGT
ARASPHHQDQVCRSGTWPTERGNRRHQSPAADPA
VGALRLRGDPLP*LQPHRAVPVCVQPAAVRGRG
GHPDLLPLHPARPAPLHDHPAATLAV*PRGPNG
ERGAGGAD*GRRSRSCSSRIHPRGAL*GEDLHPV
ETSQ*DQWGHHALRDQLQGCRLAGPKC*PLEPE
GESVQAPE*NPPPLCGSVPRDHLFLHHQGQHSK
GLWAPCHHSDCHQNFSSIHA*VRHRHPIE*DRHD
HHSDAETRSVPGSSCQCLSAGCQGGATSEVTEG
S*HY*VLFGARELSECLQPRFSTLLCC*VEACQ
PACHPAIYSG*Q*DIQWLLEPSSLSPEKLQHLLP
GTQQSQWRDQNQLCSSGYKSTNGQRPGDPGDST
LPPHHR
CLHPEF*HCGAREAGGQHREDGWRDRW
PPHVHHHSPGRDAHHQKEKKCLFLLLLLVPKEAG
QEAEGDPEWSPEGDGACGLCRQTHHQAQRQPQ*
*RLLF*FSGRQRIHRWQPRGAFPAHPHDPDSSL
PHL*PCGDELPPGPVPTRHPGG*LAAAHHADEER
PGLRVQGGIRGLTRGADSFVGHSQGG*KPQ*ES
IWEHHILRPFPGEAAGAGWRPAL*LHQCQLH*R
IPSTSALHCDSRSDAGDCKGLLENDLAGELRQHR
HGHKPGGSGQGEMCAILAR*HGGLRRH*SHPD*
NRAPGRIRHTHLHSPEERLP*DPGAPPLPLHQL
A*PRRSLLCHWPSGLRPPGQVPQPPGSWAHSGPL
QCWGWADWLLHCH*HHA*HGRE*RGGGHLQLRA
*APGPKGQPGTDRGAICVCARCHPGSVPLWQHC
HPCV*VPFSLLQYQQAGPPDKLQPNQR*ISDPQH
CDTPCAARGLQHWAPAPEP**ESKYGRAASGPL
PALPYLSGRRIQQLHQRSTDG*PQAACRLRGHP
APSTQHRGRLLEAGVRLQLLLCGDAE*DGHCPVL
YAVLA*EDLRVLWAHPGGVRLRRHRRGHHPQNI
PHL*HGPATGWLSYSPAPPVHWLACLPGHAPLQ
ALSAQSGPTTGEVAGAV*REGGTYCGPLPKWGRP
*WNLLCHLQCV*DDPAAKHH*RVPHRENTA*QQ
IQHGGDPGTV*ICIRGGTGIFKLLLAQWDGEPA
GVQRLL*PSPLLCEWQ*LGSGALRWHPA*LQGED
WWPCVPRGALHLLRGLLLPWEMLLQKAQASFST
*PATAKGPSRSTPTSKALDFWLPDHLLLF*VCG
SLGKPTVQVLGSGRLPCPPSP*EWRRCVFCSSTS
WKRLRLLGVTALLPPATSFRGLWHQTFAVWTSV
TLRCSLGHKRGPPSSHLTCMGLRPQPFCTPSPA
WALTVQHSLAGQLCPQQFLIKVFFAFLCGQWEGV
ELQGTSLLLLVFVKRDHLPGAGLGLTCRM*PLC
FFGGSFLWKRQTR*DLIIFQSVCEKKLSFGGCK
ILVSYVKKKGAGEFEYVPLRQISRAFYFFLAMSL
KAPTLGQHATEQGEMGEPEDGPFGFWGK*STSF
VHNLDVQI*TPS*RNPAATLKKAIVEPIIL*FK
IGQENQAWRSRVLSKV*VSQ*EGTNIC*VSTVCQ
GSCLALSIGHFTQSLEPPGESY*LVIISI*SSP
PMRKPTHLP***NPGFQRGR*WQ*DFSVLFSSS
SLSQAIILWRENKARNF*ADNSTNGNLVLSS*CQ
FFWEAQNFRYILVTHSQLPRKASLI*FLSQ*KQ
FPVPSGYEWTSQGNSRP*SLASA*AQYLTASGG
LGPRKLHLEGWSSPRQGMRGREFKKVQLWPSRAH
CMLGKWNHGAVVWSG*VFHEPRSKKVSSASGFL
EKGTSIPAGS*QA*KGKKGNSGKGIHMCNGKEM
*KGIGRSSLGEASPVRAQHNTGSSKR*ARVQETD
AHREYRLCPIGNKESMEL*RDALSFVLAKTPSG
PMGLPLFLSSDTVKTFP*ACTF*YHIYLSVCSL
FCCWN*ICNGS*DSDSMRNPGSLLYHGAGSPTQI
SRPMRMEHERSRQKLLPLAWALELSRSPGTPDL
IKEGLSL*RFKRKCLKAKASKGTPR*TCSFPLM
SLSPGVFQQTPGTHPHWACWPPSAPAQCPSWPSP
ACKEPVAWQICLLYAIFLDLGTSRQDEGGGRAI
*HKS*DFFLLRKG*NSWQIQKTVAFIILNGRNL
RCDFREKQTCKKKKSQAMLG*PSKGQ**FPPAHP
LIFPQPNHSLKQDSE*VLGQCTQEEIEAYGWG*
LP*DPMGQGCGKAWMRWGTSAQEFEHFPLPRKS
PEPTPPPPGGLPTPPHLQGELSLS*AEENIINAL
*VFTTGALTS*MWALFGEDARK**EAQEISPPV
FMA*IASGCILAALQHCILSGVKNLGQPGVLGP
LEGHSRPLFVGMEGDSLLLVLALSVGVACKGTNR
PYAGDSNM*AH*ILPAF*RRVCDCHHLLMRKLR
LLGEKSLAHSSTASE*MNQDLNRFFLTTETIFF
HHCISHFSQEVTHNRRD*SGTDTSVDKAQSKQQ*
A*NSFIVSCFTFTIHAKFAFHFLI*PCWF*YDS
MNISKKNVLCSSCCSVLFTPL*RTLGQLVFSLT
LELTLGAVTLLPPRASYRLKIKTN*PSPRQLLWC
VGALTSLFMRGPQLRHLPVGCWKEPINSH*NDE
DLLIWRGEG*AHKTLKGKEKLDTAVLSRFLNAR
LESGACCPSGVTWLLMWASLRTHFMSSWGLEGSS
LYPSHT*LLGAYST*HLGGGTIRKSRLLWHN*F
LGKAWGCGGQSSVFSLNENIHT*KTYMKKGPSS
TLEGVDLEHFRQENRNARPGNWNPVNTQNRGCR*
LI*QNGHFCDIAGERMGNSLPEPLGTRANLSVW
GKR*CISL*PIMFIHPPLPIATLALAVSPHQDL
HFLVAGGNPLEYIEVSVQ*DCSTQQK*GPGSSSQ
ALILLPLQE*LPNPDPETLKEMIIPWYLTALGQ
NEESHPSLGCSLPLLGWVNRSSAPSSTRSNTLE
DMGEPKRKHEQDAVPKSCQQVVLGQDPQGKKWST
QLEGRLEEKKHKRG*SCHLKSLTWLPHYLTV*A
PS*PVTSFKSQPSKTRK*EK*IQLEETS*DSDL
FTPPMQSFPVGGFPCIHV*K**NARPWLCLAGIC
L*GHRLNSRERG*WWSVGGAVLAPVSSDTFFRI
MDLILRSTAEISKPYLCT*ADSSSFLVTRDGLL
HGTDYRDVL*RSSQSFASHLPTSRRDGKRSSKGI
HQLKSTHEC*VSKRRHQHSQW*PPNLASHLSKS
SGVVHWGRYKGSARAQDERKSIGKSFRGLIIMG
LPSISENCSGW*DVDSDP*LECSENECLVALKCW
TEKYQYKSLELRVINVVHGSLVSRTLGCGGERV
IGSKPPKLQN*VSVQLLQCLWAYEYKSVGLLYD
GPTNSQCPPCPCISHGR*IMSGVLWVKGPRAVWR
LRGQSGVIPCKVRLLRGQAEYGVHIFHSSADSW
MKSSTVC*TQVTPLSITRTHE*NLIAVRKNLLS
AREDKLPISAAV*KKAGVSLKGREALVKWISGHF
HSRWVRSCGAGIMFELIHTCRARIQVDCVWSVQ
AEAPCSPTQVPPLSRPTCCCGHIYWADPGWLSP
NSKP*GTAALP*TQYPCRSLMRAAITQTH*PTGP
*VTARTSEGPSRTQSRAFLTIHIISRGYFYPTP
YSRPVGAHCKSKSTVTQFTHDYNHFQCTHFITR
WILS*PM*IRVNPYW*SYSKALFTLHSTSQSKTK
SCGLYHCLGFWTPSQAIPRFPLNSREADIFTST
GHIILHETKVSTLFAASSMNPNGLHLYSLGV**
IKHV*EEKTK*INFLKKPALCCQCFFFLFNSSSE
KQKVNNVRSMNIRYIF*LYITVKCNLFTPASPS
YLFL*MFPDNVCNMAVLKNLYNKAVTLRFMFS*
D

Frame 1

LPPQFAPRLGLERRSAGSGSPSGASRAHSQRPR
RRCGATPRPPQSRPRPPREGAELPAAARMASLA
ALALSLLLRLQLPPLPGARAQSAAGGCSFDEHYS
NCGYSVALGTNGFTWEQINTWEKPMLDQAVPTG
SFMMVNSSGRASGQKAHLLLPTLKENDTHCIDF
HYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVS
GVVTEGWVKAELAISTFWPHFYQVIFESVSLKG
HPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNV
GQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMV
TRVVNHRRFSATVSVADTAQRSVSKYRCVIRSD
GGSGVSNYAELIVKEPPTPIAPPELLAVGATYL
WIKPNANSIIGDGPIILKEVEYRTTTGTWAETHI
VDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGP
PGPPLTTRTKCADPVHGPQNVEIVDIRARQLTL
QWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEE
VIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRME
SEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQ
WKPPNETNGVITLYEINYKAVGSLDPSADLSSQR
GKVFKLRNETHHLFVGLYPGTTYSFTIKASTAK
GFGPPVTTRIATKISAPSMPEYDTDTPLNETDT
TITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRA
ADIIECFSVPVSYRNASSLDSLHYFAAELKPAN
LPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYF
QALSKANGETKINCVRLATKAPMGSAQVTPGTPL
CLLTT
GASTQNSNTVEPEKQVDNTVKMAGVIAG
LLMFIIILLGVMLTIKRRRNAYSYSYYLSQRKL
AKKQKETQSGAQREMGPVASADKPTTKLSASRND
EGFSSSSQDVNGFTDGSRGELSQPTLTIQTHPY
RTCDPVEMSYPRDQFQPAIRVADLLQHITQMKR
GQGYGFKEEYEALPEGQTASWDTAKEDENRNKNR
YGNIISYDHSRVRLLVLDGDPHSDYINANYIDG
YHRPRHYIATQGPMQETVKDFWRMIWQENSASI
VMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIE
TEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSW
PDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVH
CSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVR
ELRAQRVNLVQTEEQYVFVHDAILEACLCGNTA
IPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLN
IVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRC
LPFLISVDGESSNYINAALMDSHKQPAAFVVTQ
HPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQF
CMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIF
RICNMARPQDGYRIVQHLQYIGWPAYRDTPPSK
RSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGG
RSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNK
SNMVETLEQYKFVYEVALEYLSSF*LNGMGNLP
ESRGCCDQAPFCVNGSNWAQEL*GGTLPDSKEK
TGGPVFHGGLCTF*GVSCCRGRCCSKRPRLPFQP
NQPQPRAQAEVHPQARPWISGSQTTCFCSEFVD
LLASQLCRCWGVGGSPALLLLRSGGDVCSAPLR
HGKD*GSWGSLLCCPLQPPSGASGTRHLQSGPV*
PYDVP*ATREAPHPHT*PAWGFAHNHSVPLPQP
GP*PSSIHWPASCVHSSF**RCSLLFCVVSGRG
WNCRELLCSSLSL*KGTTSLGQGLG*PVGCNPCV
SLVVAFFGRDKQDKI*LFSKVYVKRNFLLEGVK
S*SLMSKRRGRGSLSMYL*DKSLGPFIFSWQCP
*KLPPWDSMPLSKERWVSLKMVPLVSGANRAPAL
CIIWMSKFELLPKETQQPP*KRPLWSPLYFDLK
*AKRIRPGDLGSCPKCE*VNEREPTFAKSLLYA
RDHAWHFP*DISHSP*NPQERATDLLSSPFDHLL
Q*GNPRTFLSNEILGSKGAGNGNETSPCCFLHL
L*AKQLFYGGKIRPETSEQITPQMEI*YFLPDA
SSSGKRRISDIF**HIPSSPGKPVSSNFLVSKNN
SLFLQAMNGPARETLDLDL*PVLRPNI*QPQVG
WDLGSSILKAGLAPDRA*GAENSRRYSFGPQEP
TVCWGNGTMVQ*CGVDECSMSLGARKSLRPRASW
RRGRPFLLGLNKHKKEKKETQAKGSICAMAKKC
EKALGEAVWGRPAQCGHSTTRGAARDEPGSRRQ
MPIASTDFVLLATRSPWSFREMHSASCWPRLLLG
QWGCLFSFHQTL*KHSLKRALFNITSICLSAHC
FVAGTKYAMDHETQIL*ETQGLCFTTEQGHQPR
SPGP*GWNMKGADKSCFHWHGLWSCPEVQGHQT*
SRKGCHFRGSKGSASKQRQAKEPHDELALFL**
ASPQVYFSRPRGPTPTGPAGLPRLQPNAPAGLP
QPARSL*HGKSACCMLFS*ILVHPDRMRVEGELF
NTNPKIFFCSGRGEIAGRYKRQWLLSF*MVGI*
GVTSGRNKLAKKKNLRPCWGNPARASDDFPQLI
PLFSHNPTIL*SRTVNRS*ASAHRKKLRLMDGDD
FPKIPWDKDVARLG*DGAPVPRNLNIFLYPGNL
RSQHHHPQGVSPPHPIYRVSSACHEQRKILLML
SESLQQELLPHRCGLCLGKMQGSNEKPRKFLHLC
LWPK*LQDVS*LHSNIASFLG*RIWANQGSLGL
*KATVGLSLWEWKGTVCF*CWPSLWVWPAKEPT
DPMLGTLTCELIKFFQHSKGGFVIVTIY**GN*G
S*GRNHLPTVPQLVSE*TRI*TGFFSLQRQYFS
TIVSHIFPRRLPITEETRVEQIRQWIKLKANNS
KLKIPS*SHVLRSQFMQNLHSTF*FSLVGFNMTL
*IFQKKMCSVPHVVLFCSPRYDGP*VSWSSA*P
*N*L*EQ*PCCLPEPVIGSRSRPTDLLLGSSFG
VWVL*PHCS*GDLN*GIFQLGAGRNPLTHTRMMR
ICSSGVEKDEPTKP*REKRSWTQLYSADS*MLG
WKVVPVVQVESHGC*CGQV*GHTS*AAGVWKAP
HFTLATHNYWVPTAPSTLEGALLGNRDYYGTINS
WVRHGVVVDRAQSLV*TKTYIHEKHT*KKDPHQ
H*KG*IWSTLGRKTGTQGQETGTQ*ILRTEDAD
DLFSKMVTSVT*LEKGWVTACQSHLEQGQISVSG
AKDDAFPSDPSCLFILHSPLPH*LLL*VLTRIY
ISSSLVGTP*ST*RYQSSKTALHNRSEAQGVAA
RPLSCYLCRSDCPTQIQRH*RK**FLGTSLPWDK
MKKATLP*AAACHSWAG*TGHQHQAQPGVTLWK
TWVSPRGSMNRTLFLSHVNRLCWARIPREKNGQ
PNWRVG*KKKNINVDSHVISNP*LGFPIT*QSEL
LLSL*PASNHSQVKQGNRKSKSN*KRQAEIQIC
LLLPCKVSLLEVFHVYMSRSDRMQGLGFVLQGS
AFEVID*TAGREVSGGVWGELF*LQFLLTHFSGS
WI*SSEAQQRYLSHICAHEQTLLVF**PGMGFC
MALTIEMSCRDQASLLHPTCPPPEEMGKGHQRA
FTN*NPLMNVRSLKGGINTHNGSLQT*HPTYLRA
QGWSTGADTREVQGLRMKENLLGRVLGA*SLWG
FLLYLRTALGGEMWTLILNWNVRRMSVWWP*SV
GQKSISIKAWSSG*LM*FMVP**AGLLDVEEKGS
*EVNHQNYKIESLYNYFSAFGLMNTNQWAFSMM
VQQTLSVHPVPVSPMEDE*CQVFFGSKAPGQSG
GLEGRVVSFHVKLGF*GVRQNMVSISSIALQILG
*SQAQFARPRSLL*V*LGPMSET**L*GRTCCL
PERISCPSQQLSKRRQVSL*REEKHW*NGFQVT
SIPDG*DLVELGSCLNSFIPVEHESK*IVFGLYR
LKPPALPPKCPH*AGQHAVVATYTGLIQAGYHQ
TANHREQLLCHRPNTHVDLS*EQP*LRPTDQQG
HE*QPEPVKVQVGHRAGLFLPYTLSPEVISTPLP
IQGLLEHTAKAKAQ*LNLHMIIIISSAHISSPG
GS*ASPCKSGLTHIGNHTQKHFSPYILLANQRQ
RVVASTIALASGHPHKLSQGSRSTPGRLTSSHPL
GI*YCMRPKSPHSLQPPP*IPMACTCTVWVFDR
*STYEKRKQNKSTF*KSQHCAVNVFFFFSILAQ
KSRR*IMSGQ*ISDIFFDCTLQ*SVIFLHLQVHL
IYSCKCSLTMFVTWLC*KIYTIKL*P*DSCFPK
I

Frame 2

SRLSSRRASAWNAGAPAPGARAEPAARTASGRA
GDAGPPRARPSPGPGPRGKGLSCPPPPGWRASP
RSPSACS*GCSCRHCPAPGLRAPQVAVPLMSTT
ATVVIVWL*GPMGSPGSRLTHGRNQCWTRQCPQD
LS*W*TALGEPLARRPTFSCQP*RRMTPTASTS
ITTSPAVTGPAQGP*TST*R*MVAPKGTLCGMC
PGSSLRAG*RQSSPSALSGHISIR*YLNPSH*RV
ILATSPWTRSGSLLIHAEKHLIFCDSKTWR*MW
GRMPHFSALLVGSGLSMTSFGSSNGMAGTRP*W
SPVWSTTGASQPQSVWQTLPSGASASTAV*SALM
VGLVCPTTRS*S*KSLPRPLLPQSCWLWGPHTC
GSSQMPTPSSGMAPSS*RKWNIAPPQARGQRPT
*STLPTISCGIWTPMLSMRSECSSHDQVRGVRDR
QGLPSPPGPSVQIRYMAHRTWKS*TSEPGS*PC
SGSPSATR*PAAIATTSPCSTSMCSTSSSTRPR
RSSRPPPTTPCEACAPS*PSGCDSCCLTPRAEWR
ARSWWCRLRKTFQELFL*NPSKGGPLRRRSTSS
GNLPMRPMGSSRSTRSTTRLSARWTQVLTSRAR
GGKCSSSGMKPTTSLWVCTQGPPIPSPSRPAQQR
ALGPLSPLGLPPKFQLHPCLSTTQTPH*MRQTR
PSQ*C*NPLSPGELLSVFISWLSRRSDFRSHGG
QLTLLSAFRCP*AIGMPPASILYTTLLLS*SLPT
CLSPSHLQWVTIRHTMATGTLLSLP*KATASTS
RHSAKPMERPKSTVFVWLQKHQWAAPR*PRGLH
SASSPQ
VPPPRILTLWSQRSRWTTP*RWLA*SLA
SSCSSSFSWA*CSPSKGEEMLIPTPITCPKGSW
PRSRRRPRVEPRGRWGLWPLPTNPPPSSAPAAM
MKASLLVLRTSTDSQMAAAGSFPSPPSRSRLIPT
APVTLWR*ATPGTSSNPPSGWLTCCSTSRR*RE
ARATGSRRNTRPYQRGRQLRGTQPRRMKTAIRI
DMGTSYPTTIPG*GCWCWMETRTLTTSMPTTLTD
TIDLGTTLRLKVRCRRL*RTFGE*SGRRTPPAS
SWSQTWWKWAG*NVCDTGQMTRRSTETLKSP*L
KQSPWQNTSYAPSQSRRKATMRSGSSASSTSPAG
LTTAFPAMPLAFWASSARSSSSTPRKLGP*WST
AVLGLGGLAASLPLTPCLTWPRMKGWWTSSTAC
VSSGPKGSTWYRQRSNMCLCTMPSWKRASVATLP
SLCVSSVLSTTISAGWTPRQTPAKSKMNFRPST
L*HPVCGPRTAALGSCPGTMIRIEVWTCCLWTA
ACPSLSQWTENPAITSTQH*WIATSSLPPSWSPS
TLYPTPWQTSGGWCSITTAPLW*C*MRWTLPSS
VCSTGLRRPPGAMGPSRWSSSPQTSTRTSSTEY
SASVTWPGHRMVIV*SSTSSTLAGLPTGTRPPPS
ALCSKWSDDWRSGRSSMTGGRDVLWSTA*MGEA
VVEPSVPSAVCVR*SSSKTSLTCSTS*KHCVTT
NPTWWRPWNSINLYTRWHWNI*APFSSMGWGTCR
SPEAAVTKPPFV*MAVTGLRSSEVAPCLTPRRR
LVALCSTGGSAPSEGSPVAVGDAAPKGPGFLFN
LTSHSQGPKQKYTHKQGLGFLAPRPPAFVLSLWI
SWQANCAGAGEWEAPLPSFSLGVEEMCVLLLYV
MEKIEALGGHCSAAPCNLLQGPLAPDICSLDQC
DLTMFPRPQERPPILTPNLHGASPTTILYPFPSL
GLDRPAFTGRPAVSTAVFDKGVLCFFVWSVGGG
GTAGNFSAPPCLCKKGPPPWGRAWADL*DVTPV
FLWW*LSLEETNKIRFDYFPKCM*KETFFWRV*N
LSLLCQKEGGGGV*VCTSKTNLSGLLFFPGNVL
KSSHPGTACH*ARRDG*A*RWSLWFLGQIEHQL
CA*FGCPNLNSFLKKPSSHLEKGHCGAHYTLI*N
RPRESGLEI*GLVQSVSESMRGNQHLLSLYCMP
GIMLGTFHRTFHTVLRTPRRELLTCYHLHLIIS
SNEETHAPSLVMKSWVPKGQVMAMRLLRAVFFIF
SKPSNYFMEGK*GQKLLSR*LHKWKFSTFFLMP
VLLGSAEFQIYFSNTFPAPQESQSHLIS*SVKT
IPCSFRL*MDQPGKLSTLISSQCLGPISDSLRWA
GT*EAPS*RLV*PQTGHEGQRIQEGTALALKSP
LYAGEMEPWCSSVEWMSVP*A*EQESLFGLGLP
GEGDVHSCWVLTSIKRKKRKLRQRDPYVQWQRNV
KRHWEKQSGGGQPSAGTAQHGEQQEMSQGPGDR
CPSRVQTLSYWQQGVHGALERCTQLRVGQDSFW
ANGAASFPFIRHCENIPLSVHFLISHLFVCLLIV
LLLELNMQWIMRLRFYEKPRVSALPRSRVTNPD
LQAHEDGT*KEPTKVASIGMGSGAVQKSRDTRL
DQGRAVTLEVQKEVPQSKGKQRNPTMNLLFSFDE
PLPRCISADPGDPPPLGLLASLGSSPMPQLAFP
SLQGACSMANLPAVCYFLRSWYIQTG*GWRESY
LTQILRFFSAQEGVK*LADTKDSGFYHFKW*EFK
V*LQGETNLQKKKISGHVGVTQQGPVMISPSSS
PYFPTTQPFSKAGQ*IGLRPVHTGRN*GLWMGM
TSLRSHGTRMWQGLDEMGHQCPGI*TFSFTQEIS
GANTTTPRGSPHPTPFTG*AQPVMSRGKYY*CS
LSLYNRSSYLIDVGSVWGRCKEVMRSPGNFSTC
VYGLNSFRMYLSCTPTLHPFWGEESGPTRGPWAS
RRPQ*ASLCGNGRGQFAFSAGPLCGCGLQRNQQ
TLCWGL*HVSSLNSSSILKEGL*LSPFTDEETK
APRGEITCPQFHS**VNEPGFKPVFSHYRDNIFP
PLYLTFFPGGYP*QKRLEWNRYVSG*SSKQTTV
SLKFLHSLMFYVHNSCKICIPLSDLALLVLI*L
YEYFKKKCALFLMLFCSVHPAMTDPRSAGLQLDP
RIDSRSSDPAASQSQL*AQDQDQLTFS*AAPLV
CGCSDLTVHEGTSTKASSSWVLEGTH*LTLE**
GFAHLAWRRMSPQNPKGKREAGHSCTQQIPEC*A
GKWCLLSKWSHMVANVGKSEDTLHEQLGSGRLL
TLP*PHIITGCLQHLAPWRGHY*EIEITMAQLI
PG*GMGLWWTELSL*FERKHTYMKNIHEKRTLIN
IRRGRFGAL*AGKQERKARKLEPSEYSEPRMQM
TYLAKWSLL*HSWRKDG*QLARATWNKGKSQCL
GQKMMHFPLTHHVYSSSTPHCHTSSCCKSSPGST
FPRRWWEPLRVHRGISPVRLLYTTEVRPRE*QP
GPYPVTSAGVTAQPRSRDIEGNDNSLVPHCLGT
K*RKPPFLRLQLATPGLGKQVISTKLNQE*HSGR
HG*AQEEA*TGRCS*VMSTGCAGPGSPGKKMVN
PTGG*VRRKKT*TWIVMSSQIPDLASPLLNSLS
SFLACDQLQITAK*NKEIGKVNPTRRDKLRFRFV
YSSHAKFPCWRFSMYTCLEVIECKALALSCRDL
PLRS*TEQQGERLVVECGGSCSSSSFF*HIFQD
HGSDPPKHSRDI*AIFVHMSRLF*FFSNQGWAFA
WH*L*RCLVEIKPVFCIPPAHLQKRWEKVIKGH
SPTEIHS*MLGL*KEASTLTMVASKPSIPPI*E
LRGGPLGQIQGKCKGSG*KKIYWEEF*GLDHYGA
SFYI*ELLWVVRCGL*SLIGMFGE*VSGGLEVL
DRKVSV*KPGAQGN*CSSWFLSEQDSWMWRRKG
HRK*TTKITKLSLCTITSVPLGL*IQISGPSL*W
SNKLSVSTLSLYLPWKMNNVRCSLGQRPQGSLE
A*RAEWCHSM*S*ASEGSGRIWCPYLP*LCRFL
DEVKHSLLDPGHSSEYN*DP*VKLNSCKEEPAVC
QRG*AAHLSSCLKEGRCLFKGKRSIGEMDFRSL
PFQMGEILWSWDHV*THSYL*STNPSRLCLVCT
G*SPLLSHPSAPTEQANMLLWPHILG*SRLVITK
QQTIGNSCFAIDPIPM*ISHESSHNSDPLTNRA
MSDSQNQ*RSK*DTEQGFSYHTHYLQRLFLPHS
LFKACWSTLQKQKHSNSIYT*L*SFPVHTFHHQV
DPELAHVNPG*PILVIILKSTFHPTFY*PIKDK
ELWPLPLPWLLDTLTSYPKVPAQLQGG*HLHIH
WAYNIA*DQSLHTLCSLLHESQWPALVQFGCLID
KARMRRENKINQLFKKASTVLSMFFFSFQF*LR
KAEGK*CQVNEYQIYFLTVHYSEV*SFYTCKSI
LFILVNVP*QCL*HGCVKKSIQ*SCDPEIHVFLR

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