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Sequence BNIP1.cAug05
CCTGCCGCTGCCCGTAGCCGGCGTCCCCAACATGGCGGCTCCCCAAGACGTCCACGTCCGGATCTGTAACCAAGAGATTGTCAAATTTGACCTGGAGGTGAAGGCGCTTATTCAGGATATCCGTGATTGTTCAGGACCCTTAAGTGCTCTTACTGAACTGAATACTAAAGTAAAAGAGAAATTTCAACAGTTGCGTCACA
GAATACAGGACCTGGAGCAGTTGGCTAAAGAGCAAGACAAAGAATCAGAGAAACAACTTCTACTCCAGGAAGTGGAGAATCACAAAAAGCAGATGCTCAG
CAATCAGGCCTCATGGAGGAAAGCTAATCTCACCTGCAAAATTGCAATCGACAATCTAGAGAAAGCAGAACTTCTTCAGGGAGGAGATCTCTTAAGGCAA
AGGAAAACCACCAAAGAGAGCCTGGCCCAGACATCCAGTACCATCACTGAGAGCCTCATGGGGATCAGCAGGATGATGGCCCAGCAGGTCCAGCAGAGCG
AGGAGGCCATGCAGTCTCTAGTCACTTCTTCACGAACGATCCTGGATGCAAATGAAGAATTTAAGTCCATGTCGGGCACCATCCAGCTGGGCCGGAAGCT
TATCACAAAATACAATCGCCGGGAGCTGACGGACAAGCTTCTCATCTTCCTTGCGCTAGCCCTGTTTCTTGCTACGGTCCTCTATATTGTGAAAAAGCGG
CTCTTTCCATTTTTGTGAGATCCCAAAGGTGCCAGTTCTGGCCCTTTCAGCTCCTGTTTCAGGATCTGTCCTGGTTCCTGAGCTCTAGGCTGCTAAGCTG
AGCCACACACCCCTCCGTTTGCACCAGTTGCCTGCAGGTTGGATGGAACACAGTGCCCCACTTTTCTGCAAGTAGCTGGCTTGTAAAGGGTGAACAGAGC
CATGGGAGGAAGGTCTGGCATTGGGATGCCGCCCTGGGGACATACGAACCGCCTCCTTCCACCATTGTGCACTATGGGAGGCCGCTGCTGCGTGGAGCAC
TTAAAGTCCAGCCTCCAGGACCGGATGCCCCTCCTGTCTCCCGCTCCCATCGTGCCCTTAAATGCCAGATCTGGTGGAGGGAAGAGAGAAGAGGTAGGAA
GAAAGGTGATGAAAACTCCTGGTCATTCCTTGAATAAACTTGATTTTATTTAATAGAATAAAATGTATTTGATTTTGTAAGATA
- BNIP1-5 (forward primer)
- BNIP1-6 (reverse primer)
- Single exon skipping
Frame 0
PAAARSRRPQHGGSPRRPRPDL*PRDCQI*PGGEGAYSGYP*LFRTLKCSY*TEY*SKREISTVASQ
NTGPGAVG*RARQRIRETTSTPGSGESQKADAQ
QSGLMEES*SHLQNCNRQSRESRTSSGRRSLKA
KENHQREPGPDIQYHH*EPHGDQQDDGPAGPAER
GGHAVSSHFFTNDPGCK*RI*VHVGHHPAGPEA
YHKIQSPGADGQASHLPCASPVSCYGPLYCEKA
ALSIFVRSQRCQFWPFQLLFQDLSWFLSSRLLS*
ATHPSVCTSCLQVGWNTVPHFSASSWLVKGEQS
HGRKVWHWDAALGTYEPPPSTIVHYGRPLLRGA
LKVQPPGPDAPPVSRSHRALKCQIWWREERRGRK
KGDENSWSFLE*T*FYLIE*NVFDFVR
Frame 1
LPLPVAGVPNMAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRH
RIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLS
NQASWRKANLTCKIAIDNLEKAELLQGGDLLRQ
RKTTKESLAQTSSTITESLMGISRMMAQQVQQS
EEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKL
ITKYNRRELTDKLLIFLALALFLATVLYIVKKR
LFPFL*DPKGASSGPFSSCFRICPGS*ALGC*A
EPHTPPFAPVACRLDGTQCPTFLQVAGL*RVNRA
MGGRSGIGMPPWGHTNRLLPPLCTMGGRCCVEH
LKSSLQDRMPLLSPAPIVPLNARSGGGKREEVG
RKVMKTPGHSLNKLDFI**NKMYLIL*D
Frame 2
CRCP*PASPTWRLPKTSTSGSVTKRLSNLTWR*RRLFRISVIVQDP*VLLLN*ILK*KRNFNSCVT
EYRTWSSWLKSKTKNQRNNFYSRKWRITKSRCS
AIRPHGGKLISPAKLQSTI*RKQNFFREEIS*GK
GKPPKRAWPRHPVPSLRASWGSAG*WPSRSSRA
RRPCSL*SLLHERSWMQMKNLSPCRAPSSWAGS
LSQNTIAGS*RTSFSSSLR*PCFLLRSSIL*KSG
SFHFCEIPKVPVLALSAPVSGSVLVPEL*AAKL
SHTPLRLHQLPAGWMEHSAPLFCK*LACKG*TE
PWEEGLALGCRPGDIRTASFHHCALWEAAAAWST
*SPASRTGCPSCLPLPSCP*MPDLVEGREKR*E
ER**KLLVIP*INLILFNRIKCI*FCKI
Sequence BNIP1.aAug05
CCTGCCGCTGCCCGTAGCCGGCGTCCCCAACATGGCGGCTCCCCAAGACGTCCACGTCCGGATCTGTAACCAAGAGATTGTCAAATTTGACCTGGAGGTGAAGGCGCTTATTCAGGATATCCGTGATTGTTCAGGACCCTTAAGTGCTCTTACTGAACTGAATACTAAAGTAAAAGAGAAATTTCAACAGTTGCGTCACA
GAATACAGCCAGTTCTCTATCAAAGGGCATTTATTTGGACTGCTTCCACATTTTTTTTTAAGCTAACTTATTCCCTGACAGACTTTTCTTCAACTCAGCA
TGACTTCAACTCTCCAACTACACCTGTTACCTTCAGTGACCTGGAGCAGTTGGCTAAAGAGCAAGACAAAGAATCAGAGAAACAACTTCTACTCCAGGAA
GTGGAGAATCACAAAAAGCAGATGCTCAGCAATCAGGCCTCATGGAGGAAAGCTAATCTCACCTGCAAAATTGCAATCGACAATCTAGAGAAAGCAGAAC
TTCTTCAGGGAGGAGATCTCTTAAGGCAAAGGAAAACCACCAAAGAGAGCCTGGCCCAGACATCCAGTACCATCACTGAGAGCCTCATGGGGATCAGCAG
GATGATGGCCCAGCAGGTCCAGCAGAGCGAGGAGGCCATGCAGTCTCTAGTCACTTCTTCACGAACGATCCTGGATGCAAATGAAGAATTTAAGTCCATG
TCGGGCACCATCCAGCTGGGCCGGAAGCTTATCACAAAATACAATCGCCGGGAGCTGACGGACAAGCTTCTCATCTTCCTTGCGCTAGCCCTGTTTCTTG
CTACGGTCCTCTATATTGTGAAAAAGCGGCTCTTTCCATTTTTGTGAGATCCCAAAGGTGCCAGTTCTGGCCCTTTCAGCTCCTGTTTCAGGATCTGTCC
TGGTTCCTGAGCTCTAGGCTGCTAAGCTGAGCCACACACCCCTCCGTTTGCACCAGTTGCCTGCAGGTTGGATGGAACACAGTGCCCCACTTTTCTGCAA
GTAGCTGGCTTGTAAAGGGTGAACAGAGCCATGGGAGGAAGGTCTGGCATTGGGATGCCGCCCTGGGGACATACGAACCGCCTCCTTCCACCATTGTGCA
CTATGGGAGGCCGCTGCTGCGTGGAGCACTTAAAGTCCAGCCTCCAGGACCGGATGCCCCTCCTGTCTCCCGCTCCCATCGTGCCCTTAAATGCCAGATC
TGGTGGAGGGAAGAGAGAAGAGGTAGGAAGAAAGGTGATGAAAACTCCTGGTCATTCCTTGAATAAACTTGATTTTATTTAATAGAATAAAATGTATTTG
ATTTTGTAAGATA
- BNIP1-5 (forward primer)
- BNIP1-6 (reverse primer)
- Single exon skipping
Frame 0
PAAARSRRPQHGGSPRRPRPDL*PRDCQI*PGGEGAYSGYP*LFRTLKCSY*TEY*SKREISTVASQ
NTASSLSKGIYLDCFHIFF*ANLFPDRLFFNSA
*LQLSNYTCYLQ*PGAVG*RARQRIRETTSTPG
SGESQKADAQQSGLMEES*SHLQNCNRQSRESRT
SSGRRSLKAKENHQREPGPDIQYHH*EPHGDQQ
DDGPAGPAERGGHAVSSHFFTNDPGCK*RI*VH
VGHHPAGPEAYHKIQSPGADGQASHLPCASPVSC
YGPLYCEKAALSIFVRSQRCQFWPFQLLFQDLS
WFLSSRLLS*ATHPSVCTSCLQVGWNTVPHFSA
SSWLVKGEQSHGRKVWHWDAALGTYEPPPSTIVH
YGRPLLRGALKVQPPGPDAPPVSRSHRALKCQI
WWREERRGRKKGDENSWSFLE*T*FYLIE*NVF
DFVR
Frame 1
LPLPVAGVPNMAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRH
RIQPVLYQRAFIWTASTFFFKLTYSLTDFSSTQH
DFNSPTTPVTFSDLEQLAKEQDKESEKQLLLQE
VENHKKQMLSNQASWRKANLTCKIAIDNLEKAE
LLQGGDLLRQRKTTKESLAQTSSTITESLMGISR
MMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM
SGTIQLGRKLITKYNRRELTDKLLIFLALALFL
ATVLYIVKKRLFPFL*DPKGASSGPFSSCFRICP
GS*ALGC*AEPHTPPFAPVACRLDGTQCPTFLQ
VAGL*RVNRAMGGRSGIGMPPWGHTNRLLPPLC
TMGGRCCVEHLKSSLQDRMPLLSPAPIVPLNARS
GGGKREEVGRKVMKTPGHSLNKLDFI**NKMYL
IL*D
Frame 2
CRCP*PASPTWRLPKTSTSGSVTKRLSNLTWR*RRLFRISVIVQDP*VLLLN*ILK*KRNFNSCVT
EYSQFSIKGHLFGLLPHFFLS*LIP*QTFLQLS
MTSTLQLHLLPSVTWSSWLKSKTKNQRNNFYSRK
WRITKSRCSAIRPHGGKLISPAKLQSTI*RKQN
FFREEIS*GKGKPPKRAWPRHPVPSLRASWGSA
G*WPSRSSRARRPCSL*SLLHERSWMQMKNLSPC
RAPSSWAGSLSQNTIAGS*RTSFSSSLR*PCFL
LRSSIL*KSGSFHFCEIPKVPVLALSAPVSGSV
LVPEL*AAKLSHTPLRLHQLPAGWMEHSAPLFCK
*LACKG*TEPWEEGLALGCRPGDIRTASFHHCA
LWEAAAAWST*SPASRTGCPSCLPLPSCP*MPD
LVEGREKR*EER**KLLVIP*INLILFNRIKCI*
FCKI
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