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Sequences

Sequence BIRC5.dAug05

CGCCTCTACTCCCAGAAGGCCGCGGGGGGTGGACCGCCTAAGAGGGCGTGCGCTCCCGACATGCCCCGCGGCGCGCCATTAACCGCCAGATTTGAATCGC
GGGACCCGTTGGCAGAGGTGGCGGCGGCGGCATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTTCTCAAGGACCACCGCATCTCTACATTCAAG
AACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGAGGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGT
GTTTCTTCTGCTTCAAGGAGCTGGAAGGCTGGGAGCCAGATGACGACCCCATGCAAAGGAAACCAACAATAAGAAGAAAGAATTTGAGGAAACTGCGGAG
AAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGAGGCCTCTGGCCGGAGCTGCCTGGTCCCAGAGTGGCTGCACCACTTCCAGGGTTTATTC
CCTGGTGCCACCAGCCTTCCTGTGGGCCCCTTAGCAATGTCTTAGGAAAGGAGATCAACATTTTCAAATTAGATGTTTCAACTGTGCTCTTGTTTTGTCT
TGAAAGTGGCACCAGAGGTGCTTCTGCCTGTGCAGCGGGTGCTGCTGGTAACAGTGGCTGCTTCTCTCTCTCTCTCTCTTTTTTGGGGGCTCATTTTTGC
TGTTTTGATTCCCGGGCTTACCAGGTGAGAAGTGAGGGAGGAAGAAGGCAGTGTCCCTTTTGCTAGAGCTGACAGCTTTGTTCGCGTGGGCAGAGCCTTC
CACAGTGAATGTGTCTGGACCTCATGTTGTTGAGGCTGTCACAGTCCTGAGTGTGGACTTGGCAGGTGCCTGTTGAATCTGAGCTGCAGGTTCCTTATCT
GTCACACCTGTGCCTCCTCAGAGGACAGTTTTTTTGTTGTTGTGTTTTTTTGTTTTTTTTTTTTTGGTAGATGCATGACTTGTGTGTGATGAGAGAATGG
AGACAGAGTCCCTGGCTCCTCTACTGTTTAACAACATGGCTTTCTTATTTTGTTTGAATTGTTAATTCACAGAATAGCACAAACTACAATTAAAACTAAG
CACAAAGCCATTCTAAGTCATTGGGGAAACGGGGTGAACTTCAGGTGGATGAGGAGACAGAATAGAGTGATAGGAAGCGTCTGGCAGATACTCCTTTTGC
CACTGCTGTGTGATTAGACAGGCCCAGTGAGCCGCGGGGCACATGCTGGCCGCTCCTCCCTCAGAAAAAGGCAGTGGCCTAAATCCTTTTTAAATGACTT
GGCTCGATGCTGTGGGGGACTGGCTGGGCTGCTGCAGGCCGTGTGTCTGTCAGCCCAACCTTCACATCTGTCACGTTCTCCACACGGGGGAGAGACGCAG
TCCGCCCAGGTCCCCGCTTTCTTTGGAGGCAGCAGCTCCCGCAGGGCTGAAGTCTGGCGTAAGATGATGGATTTGATTCGCCCTCCTCCCTGTCATAGAG
CTGCAGGGTGGATTGTTACAGCTTCGCTGGAAACCTCTGGAGGTCATCTCGGCTGTTCCTGAGAAATAAAAAGCCTGTCATTTCAAACACTGCTGTGGAC
CCTACTGGGTTTTTAAAATATTGTCAGTTTTTCATCGTCGTCCCTAGCCTGCCAACAGCCATCTGCCCAGACAGCCGCAGTGAGGATGAGCGTCCTGGCA
GAGACGCAGTTGTCTCTGGGCGCTTGCCAGAGCCACGAACCCCAGACCTGTTTGTATCATCCGGGCTCCTTCCGGGCAGAAACAACTGAAAATGCACTTC
AGACCCACTTATTTCTGCCACATCTGAGTCGGCCTGAGATAGACTTTTCCCTCTAAACTGGGAGAATATCACAGTGGTTTTTGTTAGCAGAAAATGCACT
CCAGCCTCTGTACTCATCTAAGCTGCTTATTTTTGATATTTGTGTCAGTCTGTAAATGGATACTTCACTTTAATAACTGTTGCTTAGTAATTGGCTTTGT
AGAGAAGCTGGAAAAAAATGGTTTTGTCTTCAACTCCTTTGCATGCCAGGCGGTGATGTGGATCTCGGCTTCTGTGAGCCTGTGCTGTGGGCAGGGCTGA
GCTGGAGCCGCCCCTCTCAGCCCGCCTGCCACGGCCTTTCCTTAAAGGCCATCCTTAAAACCAGACCCTCATGGCTACCAGCACCTGAAAGCTTCCTCGA
CATCTGTTAATAAAGCCGTAGGCCCTTGTCTAAGTGCAACCGCCTAGACTTTCTTTCAGATACATGTCCACATGTCCATTTTTCAGGTTCTCTAAGTTGG
AGTGGAGTCTGGGAAGGGTTGTGAATGAGGCTTCTGGGCTATGGGTGAGGTTCCAATGGCAGGTTAGAGCCCCTCGGGCCAACTGCCATCCTGGAAAGTA
GAGACAGCAGTGCCCGCTGCCCAGAAGAGACCAGCAAGCCAAACTGGAGCCCCCATTGCAGGCTGTCGCCATGTGGAAAGAGTAACTCACAATTGCCAAT
AAAGTCTCATGTGGTTTTATCT
  • primer-1293 (forward primer)
  • primer-1294 (reverse primer)
  • Single exon skipping

Frame 0

RLYSQKAAGGGPPKRACAPDMPRGAPLTARFES
RDPLAEVAAAAWVPRRCPLPGSPFSRTTASLHSR
TGPSWRAAPAPRSGWPRLASSTAPLRTSQTWPS
VSSASRSWKAGSQMTTPCKGNQQ*EERI*GNCG
ESAPCHRAAGCHGLRPLAGAAWSQSGCTTSRVYS
LVPPAFLWAP*QCLRKGDQHFQIRCFNCALVLS
*KWHQRCFCLCSGCCW*QWLLLSLSLFFGGSFL
LF*FPGLPGEK*GRKKAVSLLLELTALFAWAEPS
TVNVSGPHVVEAVTVLSVDLAGAC*I*AAGSLS
VTPVPPQRTVFLLLCFFVFFFLVDA*LVCDERM
ETESLAPLLFNNMAFLFCLNC*FTE*HKLQLKLS
TKPF*VIGETG*TSGG*GDRIE**EASGRYSFC
HCCVIRQAQ*AAGHMLAAPPSEKGSGLNPF*MT
WLDAVGDWLGCCRPCVCQPNLHICHVLHTGERRS
PPRSPLSLEAAAPAGLKSGVR*WI*FALLPVIE
LQGGLLQLRWKPLEVISAVPEK*KACHFKHCCG
PYWVFKILSVFHRRP*PANSHLPRQPQ*G*ASWQ
RRSCLWALARATNPRPVCIIRAPSGQKQLKMHF
RPTYFCHI*VGLR*TFPSKLGEYHSGFC*QKMH
SSLCTHLSCLFLIFVSVCKWILHFNNCCLVIGFV
EKLEKNGFVFNSFACQAVMWISASVSLCCGQG*
AGAAPLSPPATAFP*RPSLKPDPHGYQHLKASS
TSVNKAVGPCLSATA*TFFQIHVHMSIFQVL*VG
VESGKGCE*GFWAMGEVPMAG*SPSGQLPSWKV
ETAVPAAQKRPASQTGAPIAGCRHVERVTHNCQ
*SLMWFY

Frame 1

ASTPRRPRGVDRLRGRALPTCPAARH*PPDLNR
GTRWQRWRRRHGCPDVAPCLAALSQGPPHLYIQ
ELALLGGLRLHPGADGRGWLHPLPH*ERARLGPV
FLLLQGAGRLGAR*RPHAKETNNKKKEFEETAE
KVRRAIEQLAAMD*GLWPELPGPRVAAPLPGFI
PWCHQPSCGPLSNVLGKEINIFKLDVSTVLLFCL
ESGTRGASACAAGAAGNSGCFSLSLSFLGAHFC
CFDSRAYQVRSEGGRRQCPFC*S*QLCSRGQSL
PQ*MCLDLMLLRLSQS*VWTWQVPVESELQVPYL
SHLCLLRGQFFCCCVFLFFFFW*MHDLCVMREW
RQSPWLLYCLTTWLSYFV*IVNSQNSTNYN*N*
AQSHSKSLGKRGELQVDEETE*SDRKRLADTPFA
TAV*LDRPSEPRGTCWPLLPQKKAVA*ILFK*L
GSMLWGTGWAAAGRVSVSPTFTSVTFSTRGRDA
VRPGPRFLWRQQLPQG*SLA*DDGFDSPSSLS*S
CRVDCYSFAGNLWRSSRLFLRNKKPVISNTAVD
PTGFLKYCQFFIVVPSLPTAICPDSRSEDERPG
RDAVVSGRLPEPRTPDLFVSSGLLPGRNN*KCTS
DPLISATSESA*DRLFPLNWENITVVFVSRKCT
PASVLI*AAYF*YLCQSVNGYFTLITVA**LAL
*RSWKKMVLSSTPLHARR*CGSRLL*ACAVGRAE
LEPPLSARLPRPFLKGHP*NQTLMATST*KLPR
HLLIKP*ALV*VQPPRLSFRYMSTCPFFRFSKL
EWSLGRVVNEASGLWVRFQWQVRAPRANCHPGK*
RQQCPLPRRDQQAKLEPPLQAVAMWKE*LTIAN
KVSCGFI

Frame 2

PLLPEGRGGWTA*EGVRSRHAPRRAINRQI*IA
GPVGRGGGGGMGAPTLPPAWQPFLKDHRISTFK
NWPFLEGCACTPERMAEAGFIHCPTENEPDLAQ
CFFCFKELEGWEPDDDPMQRKPTIRRKNLRKLRR
KCAVPSSSWLPWIEASGRSCLVPEWLHHFQGLF
PGATSLPVGPLAMS*ERRSTFSN*MFQLCSCFV
LKVAPEVLLPVQRVLLVTVAASLSLSLFWGLIFA
VLIPGLTR*EVREEEGSVPFARADSFVRVGRAF
HSECVWTSCC*GCHSPECGLGRCLLNLSCRFLI
CHTCASSEDSFFVVVFFCFFFFGRCMTCV**ENG
DRVPGSSTV*QHGFLILFELLIHRIAQTTIKTK
HKAILSHWGNGVNFRWMRRQNRVIGSVWQILLL
PLLCD*TGPVSRGAHAGRSSLRKRQWPKSFLNDL
ARCCGGLAGLLQAVCLSAQPSHLSRSPHGGETQ
SAQVPAFFGGSSSRRAEVWRKMMDLIRPPPCHR
AAGWIVTASLETSGGHLGCS*EIKSLSFQTLLWT
LLGF*NIVSFSSSSLACQQPSAQTAAVRMSVLA
ETQLSLGACQSHEPQTCLYHPGSFRAETTENAL
QTHLFLPHLSRPEIDFSL*TGRISQWFLLAENAL
QPLYSSKLLIFDICVSL*MDTSL**LLLSNWLC
REAGKKWFCLQLLCMPGGDVDLGFCEPVLWAGL
SWSRPSQPACHGLSLKAILKTRPSWLPAPESFLD
IC**SRRPLSKCNRLDFLSDTCPHVHFSGSLSW
SGVWEGL*MRLLGYG*GSNGRLEPLGPTAILES
RDSSARCPEETSKPNWSPHCRLSPCGKSNSQLPI
KSHVVLS

Sequence BIRC5.cAug05

CGCCTCTACTCCCAGAAGGCCGCGGGGGGTGGACCGCCTAAGAGGGCGTGCGCTCCCGACATGCCCCGCGGCGCGCCATTAACCGCCAGATTTGAATCGC
GGGACCCGTTGGCAGAGGTGGCGGCGGCGGCATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTTCTCAAGGACCACCGCATCTCTACATTCAAG
AACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGAGGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGT
GTTTCTTCTGCTTCAAGGAGCTGGAAGGCTGGGAGCCAGATGACGACCCCATAGAGGAACATAAAAAGCATTCGTCCGGTTGCGCTTTCCTTTCTGTCAA
GAAGCAGTTTGAAGAATTAACCCTTGGTGAATTTTTGAAACTGGACAGAGAAAGAGCCAAGAACAAAATTGCAAAGGAAACCAACAATAAGAAGAAAGAA
TTTGAGGAAACTGCGGAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGAGGCCTCTGGCCGGAGCTGCCTGGTCCCAGAGTGGCTGCAC
CACTTCCAGGGTTTATTCCCTGGTGCCACCAGCCTTCCTGTGGGCCCCTTAGCAATGTCTTAGGAAAGGAGATCAACATTTTCAAATTAGATGTTTCAAC
TGTGCTCTTGTTTTGTCTTGAAAGTGGCACCAGAGGTGCTTCTGCCTGTGCAGCGGGTGCTGCTGGTAACAGTGGCTGCTTCTCTCTCTCTCTCTCTTTT
TTGGGGGCTCATTTTTGCTGTTTTGATTCCCGGGCTTACCAGGTGAGAAGTGAGGGAGGAAGAAGGCAGTGTCCCTTTTGCTAGAGCTGACAGCTTTGTT
CGCGTGGGCAGAGCCTTCCACAGTGAATGTGTCTGGACCTCATGTTGTTGAGGCTGTCACAGTCCTGAGTGTGGACTTGGCAGGTGCTGGCTGGGCTGCT
GCAGGCCGTGTGTCTGTCAGCCCAACCTTCACATCTGTCACGTTCTCCACACGGGGGAGAGACGCAGTCCGCCCAGGTCCCCGCTTTCTTTGGAGGCAGC
AGCTCCCGCAGGGCTGAAGTCTGGCGTAAGATGATGGATTTGATTCGCCCTCCTCCCTGTCATAGAGCTGCAGGGTGGATTGTTACAGCTTCGCTGGAAA
CCTCTGGAGGTCATCTCGGCTGTTCCTGAGAAATAAAAAGCCTGTCATTTCAAACACTGCTGTGGACCCTACTGGGTTTTTAAAATATTGTCAGTTTTTC
ATCGTCGTCCCTAGCCTGCCAACAGCCATCTGCCCAGACAGCCGCAGTGAGGATGAGCGTCCTGGCAGAGACGCAGTTGTCTCTGGGCGCTTGCCAGAGC
CACGAACCCCAGACCTGTTTGTATCATCCGGGCTCCTTCCGGGCAGAAACAACTGAAAATGCACTTCAGACCCACTTATTTCTGCCACATCTGAGTCGGC
CTGAGATAGACTTTTCCCTCTAAACTGGGAGAATATCACAGTGGTTTTTGTTAGCAGAAAATGCACTCCAGCCTCTGTACTCATCTAAGCTGCTTATTTT
TGATATTTGTGTCAGTCTGTAAATGGATACTTCACTTTAATAACTGTTGCTTAGTAATTGGCTTTGTAGAGAAGCTGGAAAAAAATGGTTTTGTCTTCAA
CTCCTTTGCATGCCAGGCGGTGATGTGGATCTCGGCTTCTGTGAGCCTGTGCTGTGGGCAGGGCTGAGCTGGAGCCGCCCCTCTCAGCCCGCCTGCCACG
GCCTTTCCTTAAAGGCCATCCTTAAAACCAGACCCTCATGGCTACCAGCACCTGAAAGCTTCCTCGACATCTGTTAATAAAGCCGTAGGCCCTTGTCTAA
GTGCAACCGCCTAGACTTTCTTTCAGATACATGTCCACATGTCCATTTTTCAGGTTCTCTAAGTTGGAGTGGAGTCTGGGAAGGGTTGTGAATGAGGCTT
CTGGGCTATGGGTGAGGTTCCAATGGCAGGTTAGAGCCCCTCGGGCCAACTGCCATCCTGGAAAGTAGAGACAGCAGTGCCCGCTGCCCAGAAGAGACCA
GCAAGCCAAACTGGAGCCCCCATTGCAGGCTGTCGCCATGTGGAAAGAGTAACTCACAATTGCCAATAAAGTCTCATGTGGTTTTATCT
  • primer-1293 (forward primer)
  • primer-1294 (reverse primer)
  • Single exon skipping

Frame 0

RLYSQKAAGGGPPKRACAPDMPRGAPLTARFES
RDPLAEVAAAAWVPRRCPLPGSPFSRTTASLHSR
TGPSWRAAPAPRSGWPRLASSTAPLRTSQTWPS
VSSASRSWKAGSQMTTP*RNIKSIRPVALSFLS
RSSLKN*PLVNF*NWTEKEPRTKLQRKPTIRRKN
LRKLRRKCAVPSSSWLPWIEASGRSCLVPEWLH
HFQGLFPGATSLPVGPLAMS*ERRSTFSN*MFQ
LCSCFVLKVAPEVLLPVQRVLLVTVAASLSLSLF
WGLIFAVLIPGLTR*EVREEEGSVPFARADSFV
RVGRAFHSECVWTSCC*GCHSPECGLGRCWLGC
CRPCVCQPNLHICHVLHTGERRSPPRSPLSLEAA
APAGLKSGVR*WI*FALLPVIELQGGLLQLRWK
PLEVISAVPEK*KACHFKHCCGPYWVFKILSVF
HRRP*PANSHLPRQPQ*G*ASWQRRSCLWALARA
TNPRPVCIIRAPSGQKQLKMHFRPTYFCHI*VG
LR*TFPSKLGEYHSGFC*QKMHSSLCTHLSCLF
LIFVSVCKWILHFNNCCLVIGFVEKLEKNGFVFN
SFACQAVMWISASVSLCCGQG*AGAAPLSPPAT
AFP*RPSLKPDPHGYQHLKASSTSVNKAVGPCL
SATA*TFFQIHVHMSIFQVL*VGVESGKGCE*GF
WAMGEVPMAG*SPSGQLPSWKVETAVPAAQKRP
ASQTGAPIAGCRHVERVTHNCQ*SLMWFY

Frame 1

ASTPRRPRGVDRLRGRALPTCPAARH*PPDLNR
GTRWQRWRRRHGCPDVAPCLAALSQGPPHLYIQ
ELALLGGLRLHPGADGRGWLHPLPH*ERARLGPV
FLLLQGAGRLGAR*RPHRGT*KAFVRLRFPFCQ
EAV*RINPW*IFETGQRKSQEQNCKGNQQ*EER
I*GNCGESAPCHRAAGCHGLRPLAGAAWSQSGCT
TSRVYSLVPPAFLWAP*QCLRKGDQHFQIRCFN
CALVLS*KWHQRCFCLCSGCCW*QWLLLSLSLF
FGGSFLLF*FPGLPGEK*GRKKAVSLLLELTALF
AWAEPSTVNVSGPHVVEAVTVLSVDLAGAGWAA
AGRVSVSPTFTSVTFSTRGRDAVRPGPRFLWRQ
QLPQG*SLA*DDGFDSPSSLS*SCRVDCYSFAGN
LWRSSRLFLRNKKPVISNTAVDPTGFLKYCQFF
IVVPSLPTAICPDSRSEDERPGRDAVVSGRLPE
PRTPDLFVSSGLLPGRNN*KCTSDPLISATSESA
*DRLFPLNWENITVVFVSRKCTPASVLI*AAYF
*YLCQSVNGYFTLITVA**LAL*RSWKKMVLSS
TPLHARR*CGSRLL*ACAVGRAELEPPLSARLPR
PFLKGHP*NQTLMATST*KLPRHLLIKP*ALV*
VQPPRLSFRYMSTCPFFRFSKLEWSLGRVVNEA
SGLWVRFQWQVRAPRANCHPGK*RQQCPLPRRDQ
QAKLEPPLQAVAMWKE*LTIANKVSCGFI

Frame 2

PLLPEGRGGWTA*EGVRSRHAPRRAINRQI*IA
GPVGRGGGGGMGAPTLPPAWQPFLKDHRISTFK
NWPFLEGCACTPERMAEAGFIHCPTENEPDLAQ
CFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVK
KQFEELTLGEFLKLDRERAKNKIAKETNNKKKE
FEETAEKVRRAIEQLAAMD*GLWPELPGPRVAA
PLPGFIPWCHQPSCGPLSNVLGKEINIFKLDVST
VLLFCLESGTRGASACAAGAAGNSGCFSLSLSF
LGAHFCCFDSRAYQVRSEGGRRQCPFC*S*QLC
SRGQSLPQ*MCLDLMLLRLSQS*VWTWQVLAGLL
QAVCLSAQPSHLSRSPHGGETQSAQVPAFFGGS
SSRRAEVWRKMMDLIRPPPCHRAAGWIVTASLE
TSGGHLGCS*EIKSLSFQTLLWTLLGF*NIVSFS
SSSLACQQPSAQTAAVRMSVLAETQLSLGACQS
HEPQTCLYHPGSFRAETTENALQTHLFLPHLSR
PEIDFSL*TGRISQWFLLAENALQPLYSSKLLIF
DICVSL*MDTSL**LLLSNWLCREAGKKWFCLQ
LLCMPGGDVDLGFCEPVLWAGLSWSRPSQPACH
GLSLKAILKTRPSWLPAPESFLDIC**SRRPLSK
CNRLDFLSDTCPHVHFSGSLSWSGVWEGL*MRL
LGYG*GSNGRLEPLGPTAILESRDSSARCPEET
SKPNWSPHCRLSPCGKSNSQLPIKSHVVLS

Sequence BIRC5.bAug05

CGCCTCTACTCCCAGAAGGCCGCGGGGGGTGGACCGCCTAAGAGGGCGTGCGCTCCCGACATGCCCCGCGGCGCGCCATTAACCGCCAGATTTGAATCGC
GGGACCCGTTGGCAGAGGTGGCGGCGGCGGCATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTTCTCAAGGACCACCGCATCTCTACATTCAAG
AACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGAGGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGT
GTTTCTTCTGCTTCAAGGAGCTGGAAGGCTGGGAGCCAGATGACGACCCCATAGAGGAACATAAAAAGCATTCGTCCGGTTGCGCTTTCCTTTCTGTCAA
GAAGCAGTTTGAAGAATTAACCCTTGGTGAATTTTTGAAACTGGACAGAGAAAGAGCCAAGAACAAAATTGCAAAGGAAACCAACAATAAGAAGAAAGAA
TTTGAGGAAACTGCGGAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGAGGCCTCTGGCCGGAGCTGCCTGGTCCCAGAGTGGCTGCAC
CACTTCCAGGGTTTATTCCCTGGTGCCACCAGCCTTCCTGTGGGCCCCTTAGCAATGTCTTAGGAAAGGAGATCAACATTTTCAAATTAGATGTTTCAAC
TGTGCTCTTGTTTTGTCTTGAAAGTGGCACCAGAGGTGCTTCTGCCTGTGCAGCGGGTGCTGCTGGTAACAGTGGCTGCTTCTCTCTCTCTCTCTCTTTT
TTGGGGGCTCATTTTTGCTGTTTTGATTCCCGGGCTTACCAGGTGAGAAGTGAGGGAGGAAGAAGGCAGTGTCCCTTTTGCTAGAGCTGACAGCTTTGTT
CGCGTGGGCAGAGCCTTCCACAGTGAATGTGTCTGGACCTCATGTTGTTGAGGCTGTCACAGTCCTGAGTGTGGACTTGGCAGGTGCCTGTTGAATCTGA
GCTGCAGGTTCCTTATCTGTCACACCTGTGCCTCCTCAGAGGACAGTTTTTTTGTTGTTGTGTTTTTTTGTTTTTTTTTTTTTGGTAGATGCATGACTTG
TGTGTGATGAGAGAATGGAGACAGAGTCCCTGGCTCCTCTACTGTTTAACAACATGGCTTTCTTATTTTGTTTGAATTGTTAATTCACAGAATAGCACAA
ACTACAATTAAAACTAAGCACAAAGCCATTCTAAGTCATTGGGGAAACGGGGTGAACTTCAGGTGGATGAGGAGACAGAATAGAGTGATAGGAAGCGTCT
GGCAGATACTCCTTTTGCCACTGCTGTGTGATTAGACAGGCCCAGTGAGCCGCGGGGCACATGCTGGCCGCTCCTCCCTCAGAAAAAGGCAGTGGCCTAA
ATCCTTTTTAAATGACTTGGCTCGATGCTGTGGGGGACTGGCTGGGCTGCTGCAGGCCGTGTGTCTGTCAGCCCAACCTTCACATCTGTCACGTTCTCCA
CACGGGGGAGAGACGCAGTCCGCCCAGGTCCCCGCTTTCTTTGGAGGCAGCAGCTCCCGCAGGGCTGAAGTCTGGCGTAAGATGATGGATTTGATTCGCC
CTCCTCCCTGTCATAGAGCTGCAGGGTGGATTGTTACAGCTTCGCTGGAAACCTCTGGAGGTCATCTCGGCTGTTCCTGAGAAATAAAAAGCCTGTCATT
TCAAACACTGCTGTGGACCCTACTGGGTTTTTAAAATATTGTCAGTTTTTCATCGTCGTCCCTAGCCTGCCAACAGCCATCTGCCCAGACAGCCGCAGTG
AGGATGAGCGTCCTGGCAGAGACGCAGTTGTCTCTGGGCGCTTGCCAGAGCCACGAACCCCAGACCTGTTTGTATCATCCGGGCTCCTTCCGGGCAGAAA
CAACTGAAAATGCACTTCAGACCCACTTATTTCTGCCACATCTGAGTCGGCCTGAGATAGACTTTTCCCTCTAAACTGGGAGAATATCACAGTGGTTTTT
GTTAGCAGAAAATGCACTCCAGCCTCTGTACTCATCTAAGCTGCTTATTTTTGATATTTGTGTCAGTCTGTAAATGGATACTTCACTTTAATAACTGTTG
CTTAGTAATTGGCTTTGTAGAGAAGCTGGAAAAAAATGGTTTTGTCTTCAACTCCTTTGCATGCCAGGCGGTGATGTGGATCTCGGCTTCTGTGAGCCTG
TGCTGTGGGCAGGGCTGAGCTGGAGCCGCCCCTCTCAGCCCGCCTGCCACGGCCTTTCCTTAAAGGCCATCCTTAAAACCAGACCCTCATGGCTACCAGC
ACCTGAAAGCTTCCTCGACATCTGTTAATAAAGCCGTAGGCCCTTGTCTAAGTGCAACCGCCTAGACTTTCTTTCAGATACATGTCCACATGTCCATTTT
TCAGGTTCTCTAAGTTGGAGTGGAGTCTGGGAAGGGTTGTGAATGAGGCTTCTGGGCTATGGGTGAGGTTCCAATGGCAGGTTAGAGCCCCTCGGGCCAA
CTGCCATCCTGGAAAGTAGAGACAGCAGTGCCCGCTGCCCAGAAGAGACCAGCAAGCCAAACTGGAGCCCCCATTGCAGGCTGTCGCCATGTGGAAAGAG
TAACTCACAATTGCCAATAAAGTCTCATGTGGTTTTATCT
  • primer-1293 (forward primer)
  • primer-1294 (reverse primer)
  • Single exon skipping

Frame 0

RLYSQKAAGGGPPKRACAPDMPRGAPLTARFES
RDPLAEVAAAAWVPRRCPLPGSPFSRTTASLHSR
TGPSWRAAPAPRSGWPRLASSTAPLRTSQTWPS
VSSASRSWKAGSQMTTP*RNIKSIRPVALSFLS
RSSLKN*PLVNF*NWTEKEPRTKLQRKPTIRRKN
LRKLRRKCAVPSSSWLPWIEASGRSCLVPEWLH
HFQGLFPGATSLPVGPLAMS*ERRSTFSN*MFQ
LCSCFVLKVAPEVLLPVQRVLLVTVAASLSLSLF
WGLIFAVLIPGLTR*EVREEEGSVPFARADSFV
RVGRAFHSECVWTSCC*GCHSPECGLGRCLLNL
SCRFLICHTCASSEDSFFVVVFFCFFFFGRCMTC
V**ENGDRVPGSSTV*QHGFLILFELLIHRIAQ
TTIKTKHKAILSHWGNGVNFRWMRRQNRVIGSV
WQILLLPLLCD*TGPVSRGAHAGRSSLRKRQWPK
SFLNDLARCCGGLAGLLQAVCLSAQPSHLSRSP
HGGETQSAQVPAFFGGSSSRRAEVWRKMMDLIR
PPPCHRAAGWIVTASLETSGGHLGCS*EIKSLSF
QTLLWTLLGF*NIVSFSSSSLACQQPSAQTAAV
RMSVLAETQLSLGACQSHEPQTCLYHPGSFRAE
TTENALQTHLFLPHLSRPEIDFSL*TGRISQWFL
LAENALQPLYSSKLLIFDICVSL*MDTSL**LL
LSNWLCREAGKKWFCLQLLCMPGGDVDLGFCEP
VLWAGLSWSRPSQPACHGLSLKAILKTRPSWLPA
PESFLDIC**SRRPLSKCNRLDFLSDTCPHVHF
SGSLSWSGVWEGL*MRLLGYG*GSNGRLEPLGP
TAILESRDSSARCPEETSKPNWSPHCRLSPCGKS
NSQLPIKSHVVLS

Frame 1

ASTPRRPRGVDRLRGRALPTCPAARH*PPDLNR
GTRWQRWRRRHGCPDVAPCLAALSQGPPHLYIQ
ELALLGGLRLHPGADGRGWLHPLPH*ERARLGPV
FLLLQGAGRLGAR*RPHRGT*KAFVRLRFPFCQ
EAV*RINPW*IFETGQRKSQEQNCKGNQQ*EER
I*GNCGESAPCHRAAGCHGLRPLAGAAWSQSGCT
TSRVYSLVPPAFLWAP*QCLRKGDQHFQIRCFN
CALVLS*KWHQRCFCLCSGCCW*QWLLLSLSLF
FGGSFLLF*FPGLPGEK*GRKKAVSLLLELTALF
AWAEPSTVNVSGPHVVEAVTVLSVDLAGAC*I*
AAGSLSVTPVPPQRTVFLLLCFFVFFFLVDA*L
VCDERMETESLAPLLFNNMAFLFCLNC*FTE*HK
LQLKLSTKPF*VIGETG*TSGG*GDRIE**EAS
GRYSFCHCCVIRQAQ*AAGHMLAAPPSEKGSGL
NPF*MTWLDAVGDWLGCCRPCVCQPNLHICHVLH
TGERRSPPRSPLSLEAAAPAGLKSGVR*WI*FA
LLPVIELQGGLLQLRWKPLEVISAVPEK*KACH
FKHCCGPYWVFKILSVFHRRP*PANSHLPRQPQ*
G*ASWQRRSCLWALARATNPRPVCIIRAPSGQK
QLKMHFRPTYFCHI*VGLR*TFPSKLGEYHSGF
C*QKMHSSLCTHLSCLFLIFVSVCKWILHFNNCC
LVIGFVEKLEKNGFVFNSFACQAVMWISASVSL
CCGQG*AGAAPLSPPATAFP*RPSLKPDPHGYQ
HLKASSTSVNKAVGPCLSATA*TFFQIHVHMSIF
QVL*VGVESGKGCE*GFWAMGEVPMAG*SPSGQ
LPSWKVETAVPAAQKRPASQTGAPIAGCRHVER
VTHNCQ*SLMWFY

Frame 2

PLLPEGRGGWTA*EGVRSRHAPRRAINRQI*IA
GPVGRGGGGGMGAPTLPPAWQPFLKDHRISTFK
NWPFLEGCACTPERMAEAGFIHCPTENEPDLAQ
CFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVK
KQFEELTLGEFLKLDRERAKNKIAKETNNKKKE
FEETAEKVRRAIEQLAAMD*GLWPELPGPRVAA
PLPGFIPWCHQPSCGPLSNVLGKEINIFKLDVST
VLLFCLESGTRGASACAAGAAGNSGCFSLSLSF
LGAHFCCFDSRAYQVRSEGGRRQCPFC*S*QLC
SRGQSLPQ*MCLDLMLLRLSQS*VWTWQVPVESE
LQVPYLSHLCLLRGQFFCCCVFLFFFFW*MHDL
CVMREWRQSPWLLYCLTTWLSYFV*IVNSQNST
NYN*N*AQSHSKSLGKRGELQVDEETE*SDRKRL
ADTPFATAV*LDRPSEPRGTCWPLLPQKKAVA*
ILFK*LGSMLWGTGWAAAGRVSVSPTFTSVTFS
TRGRDAVRPGPRFLWRQQLPQG*SLA*DDGFDSP
SSLS*SCRVDCYSFAGNLWRSSRLFLRNKKPVI
SNTAVDPTGFLKYCQFFIVVPSLPTAICPDSRS
EDERPGRDAVVSGRLPEPRTPDLFVSSGLLPGRN
N*KCTSDPLISATSESA*DRLFPLNWENITVVF
VSRKCTPASVLI*AAYF*YLCQSVNGYFTLITV
A**LAL*RSWKKMVLSSTPLHARR*CGSRLL*AC
AVGRAELEPPLSARLPRPFLKGHP*NQTLMATS
T*KLPRHLLIKP*ALV*VQPPRLSFRYMSTCPF
FRFSKLEWSLGRVVNEASGLWVRFQWQVRAPRAN
CHPGK*RQQCPLPRRDQQAKLEPPLQAVAMWKE
*LTIANKVSCGFI

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