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Supplementary data
RBFOX2 enforces the mesenchymal splicing signature in normal and cancer tissues
1. Initial RefSeq screen / epithelium and mesenchyme (fetal colon)
Transcript map
: ADAR epithelium
Exon
Length: 107
Transcript: NM_001025107
Length: 107
Transcript: NM_001025107
Exon
Length: 1586
Transcript: NM_001025107
Length: 1586
Transcript: NM_001025107
Exon
Length: 184
Transcript: NM_001025107
Length: 184
Transcript: NM_001025107
Exon
Length: 149
Transcript: NM_001025107
Length: 149
Transcript: NM_001025107
Exon
Length: 145
Transcript: NM_001025107
Length: 145
Transcript: NM_001025107
Exon
Length: 191
Transcript: NM_001025107
Length: 191
Transcript: NM_001025107
Exon
Length: 226
Transcript: NM_001025107
Length: 226
Transcript: NM_001025107
Exon
Length: 172
Transcript: NM_001025107
Length: 172
Transcript: NM_001025107
Exon
Length: 94
Transcript: NM_001025107
Length: 94
Transcript: NM_001025107
Exon
Length: 123
Transcript: NM_001025107
Length: 123
Transcript: NM_001025107
Exon
Length: 134
Transcript: NM_001025107
Length: 134
Transcript: NM_001025107
Exon
Length: 183
Transcript: NM_001025107
Length: 183
Transcript: NM_001025107
Exon
Length: 113
Transcript: NM_001025107
Length: 113
Transcript: NM_001025107
Exon
Length: 128
Transcript: NM_001025107
Length: 128
Transcript: NM_001025107
Exon
Length: 2987
Transcript: NM_001025107
Length: 2987
Transcript: NM_001025107
Intron
Length: 25228
Transcript: NM_001025107
Length: 25228
Transcript: NM_001025107
Intron
Length: 2455
Transcript: NM_001025107
Length: 2455
Transcript: NM_001025107
Intron
Length: 425
Transcript: NM_001025107
Length: 425
Transcript: NM_001025107
Intron
Length: 560
Transcript: NM_001025107
Length: 560
Transcript: NM_001025107
Intron
Length: 127
Transcript: NM_001025107
Length: 127
Transcript: NM_001025107
Intron
Length: 6395
Transcript: NM_001025107
Length: 6395
Transcript: NM_001025107
Intron
Length: 255
Transcript: NM_001025107
Length: 255
Transcript: NM_001025107
Intron
Length: 294
Transcript: NM_001025107
Length: 294
Transcript: NM_001025107
Intron
Length: 695
Transcript: NM_001025107
Length: 695
Transcript: NM_001025107
Intron
Length: 292
Transcript: NM_001025107
Length: 292
Transcript: NM_001025107
Intron
Length: 1761
Transcript: NM_001025107
Length: 1761
Transcript: NM_001025107
Intron
Length: 315
Transcript: NM_001025107
Length: 315
Transcript: NM_001025107
Intron
Length: 408
Transcript: NM_001025107
Length: 408
Transcript: NM_001025107
Intron
Length: 173
Transcript: NM_001025107
Length: 173
Transcript: NM_001025107
Reaction
Expected peak: 221
32.1M
refseq_ADAR.F3
refseq_ADAR.R3
Expected peak: 221
32.1M
refseq_ADAR.F3
refseq_ADAR.R3
Exon
Length: 215
Transcript: NM_001111
Length: 215
Transcript: NM_001111
Exon
Length: 1586
Transcript: NM_001111
Length: 1586
Transcript: NM_001111
Exon
Length: 184
Transcript: NM_001111
Length: 184
Transcript: NM_001111
Exon
Length: 149
Transcript: NM_001111
Length: 149
Transcript: NM_001111
Exon
Length: 145
Transcript: NM_001111
Length: 145
Transcript: NM_001111
Exon
Length: 191
Transcript: NM_001111
Length: 191
Transcript: NM_001111
Exon
Length: 226
Transcript: NM_001111
Length: 226
Transcript: NM_001111
Exon
Length: 172
Transcript: NM_001111
Length: 172
Transcript: NM_001111
Exon
Length: 94
Transcript: NM_001111
Length: 94
Transcript: NM_001111
Exon
Length: 123
Transcript: NM_001111
Length: 123
Transcript: NM_001111
Exon
Length: 134
Transcript: NM_001111
Length: 134
Transcript: NM_001111
Exon
Length: 183
Transcript: NM_001111
Length: 183
Transcript: NM_001111
Exon
Length: 113
Transcript: NM_001111
Length: 113
Transcript: NM_001111
Exon
Length: 128
Transcript: NM_001111
Length: 128
Transcript: NM_001111
Exon
Length: 2987
Transcript: NM_001111
Length: 2987
Transcript: NM_001111
Intron
Length: 5365
Transcript: NM_001111
Length: 5365
Transcript: NM_001111
Intron
Length: 2455
Transcript: NM_001111
Length: 2455
Transcript: NM_001111
Intron
Length: 425
Transcript: NM_001111
Length: 425
Transcript: NM_001111
Intron
Length: 560
Transcript: NM_001111
Length: 560
Transcript: NM_001111
Intron
Length: 127
Transcript: NM_001111
Length: 127
Transcript: NM_001111
Intron
Length: 6395
Transcript: NM_001111
Length: 6395
Transcript: NM_001111
Intron
Length: 255
Transcript: NM_001111
Length: 255
Transcript: NM_001111
Intron
Length: 294
Transcript: NM_001111
Length: 294
Transcript: NM_001111
Intron
Length: 695
Transcript: NM_001111
Length: 695
Transcript: NM_001111
Intron
Length: 292
Transcript: NM_001111
Length: 292
Transcript: NM_001111
Intron
Length: 1761
Transcript: NM_001111
Length: 1761
Transcript: NM_001111
Intron
Length: 315
Transcript: NM_001111
Length: 315
Transcript: NM_001111
Intron
Length: 408
Transcript: NM_001111
Length: 408
Transcript: NM_001111
Intron
Length: 173
Transcript: NM_001111
Length: 173
Transcript: NM_001111
Reaction
Expected peak: 221
32.1M
refseq_ADAR.F3
refseq_ADAR.R3
Expected peak: 221
32.1M
refseq_ADAR.F3
refseq_ADAR.R3
Exon
Length: 215
Transcript: NM_015840
Length: 215
Transcript: NM_015840
Exon
Length: 1586
Transcript: NM_015840
Length: 1586
Transcript: NM_015840
Exon
Length: 184
Transcript: NM_015840
Length: 184
Transcript: NM_015840
Exon
Length: 149
Transcript: NM_015840
Length: 149
Transcript: NM_015840
Exon
Length: 145
Transcript: NM_015840
Length: 145
Transcript: NM_015840
Exon
Length: 191
Transcript: NM_015840
Length: 191
Transcript: NM_015840
Exon
Length: 148
Transcript: NM_015840
Length: 148
Transcript: NM_015840
Exon
Length: 172
Transcript: NM_015840
Length: 172
Transcript: NM_015840
Exon
Length: 94
Transcript: NM_015840
Length: 94
Transcript: NM_015840
Exon
Length: 123
Transcript: NM_015840
Length: 123
Transcript: NM_015840
Exon
Length: 134
Transcript: NM_015840
Length: 134
Transcript: NM_015840
Exon
Length: 183
Transcript: NM_015840
Length: 183
Transcript: NM_015840
Exon
Length: 113
Transcript: NM_015840
Length: 113
Transcript: NM_015840
Exon
Length: 128
Transcript: NM_015840
Length: 128
Transcript: NM_015840
Exon
Length: 2987
Transcript: NM_015840
Length: 2987
Transcript: NM_015840
Intron
Length: 5365
Transcript: NM_015840
Length: 5365
Transcript: NM_015840
Intron
Length: 2455
Transcript: NM_015840
Length: 2455
Transcript: NM_015840
Intron
Length: 425
Transcript: NM_015840
Length: 425
Transcript: NM_015840
Intron
Length: 560
Transcript: NM_015840
Length: 560
Transcript: NM_015840
Intron
Length: 127
Transcript: NM_015840
Length: 127
Transcript: NM_015840
Intron
Length: 6395
Transcript: NM_015840
Length: 6395
Transcript: NM_015840
Intron
Length: 333
Transcript: NM_015840
Length: 333
Transcript: NM_015840
Intron
Length: 294
Transcript: NM_015840
Length: 294
Transcript: NM_015840
Intron
Length: 695
Transcript: NM_015840
Length: 695
Transcript: NM_015840
Intron
Length: 292
Transcript: NM_015840
Length: 292
Transcript: NM_015840
Intron
Length: 1761
Transcript: NM_015840
Length: 1761
Transcript: NM_015840
Intron
Length: 315
Transcript: NM_015840
Length: 315
Transcript: NM_015840
Intron
Length: 408
Transcript: NM_015840
Length: 408
Transcript: NM_015840
Intron
Length: 173
Transcript: NM_015840
Length: 173
Transcript: NM_015840
Reaction
Expected peak: 143
22.4M
refseq_ADAR.F3
refseq_ADAR.R3
Expected peak: 143
22.4M
refseq_ADAR.F3
refseq_ADAR.R3
Exon
Length: 215
Transcript: NM_015841
Length: 215
Transcript: NM_015841
Exon
Length: 1586
Transcript: NM_015841
Length: 1586
Transcript: NM_015841
Exon
Length: 184
Transcript: NM_015841
Length: 184
Transcript: NM_015841
Exon
Length: 149
Transcript: NM_015841
Length: 149
Transcript: NM_015841
Exon
Length: 145
Transcript: NM_015841
Length: 145
Transcript: NM_015841
Exon
Length: 134
Transcript: NM_015841
Length: 134
Transcript: NM_015841
Exon
Length: 148
Transcript: NM_015841
Length: 148
Transcript: NM_015841
Exon
Length: 172
Transcript: NM_015841
Length: 172
Transcript: NM_015841
Exon
Length: 94
Transcript: NM_015841
Length: 94
Transcript: NM_015841
Exon
Length: 123
Transcript: NM_015841
Length: 123
Transcript: NM_015841
Exon
Length: 134
Transcript: NM_015841
Length: 134
Transcript: NM_015841
Exon
Length: 183
Transcript: NM_015841
Length: 183
Transcript: NM_015841
Exon
Length: 113
Transcript: NM_015841
Length: 113
Transcript: NM_015841
Exon
Length: 128
Transcript: NM_015841
Length: 128
Transcript: NM_015841
Exon
Length: 2987
Transcript: NM_015841
Length: 2987
Transcript: NM_015841
Intron
Length: 5365
Transcript: NM_015841
Length: 5365
Transcript: NM_015841
Intron
Length: 2455
Transcript: NM_015841
Length: 2455
Transcript: NM_015841
Intron
Length: 425
Transcript: NM_015841
Length: 425
Transcript: NM_015841
Intron
Length: 560
Transcript: NM_015841
Length: 560
Transcript: NM_015841
Intron
Length: 184
Transcript: NM_015841
Length: 184
Transcript: NM_015841
Intron
Length: 6395
Transcript: NM_015841
Length: 6395
Transcript: NM_015841
Intron
Length: 333
Transcript: NM_015841
Length: 333
Transcript: NM_015841
Intron
Length: 294
Transcript: NM_015841
Length: 294
Transcript: NM_015841
Intron
Length: 695
Transcript: NM_015841
Length: 695
Transcript: NM_015841
Intron
Length: 292
Transcript: NM_015841
Length: 292
Transcript: NM_015841
Intron
Length: 1761
Transcript: NM_015841
Length: 1761
Transcript: NM_015841
Intron
Length: 315
Transcript: NM_015841
Length: 315
Transcript: NM_015841
Intron
Length: 408
Transcript: NM_015841
Length: 408
Transcript: NM_015841
Intron
Length: 173
Transcript: NM_015841
Length: 173
Transcript: NM_015841
Reaction
Expected peak: 143
22.4M
refseq_ADAR.F3
refseq_ADAR.R3
Expected peak: 143
22.4M
refseq_ADAR.F3
refseq_ADAR.R3
refseq_ADAR.F3
CTCTCCGTGTCTTGATTGGG
CTCTCCGTGTCTTGATTGGG
refseq_ADAR.R3
GGGCTGGAAGCTGTTAGTCA
GGGCTGGAAGCTGTTAGTCA