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Supplementary data
RBFOX2 enforces the mesenchymal splicing signature in normal and cancer tissues
7. 26 switch-like targets from epithelium and mesenchyme (fetal colon) in RBFOX2, MBNL1, PTBP and ESRP knockdowns
Transcript map
: PB1 Control (MDA-MB-231)
Exon
Length: 141
Transcript: NM_018165
Length: 141
Transcript: NM_018165
Exon
Length: 98
Transcript: NM_018165
Length: 98
Transcript: NM_018165
Exon
Length: 148
Transcript: NM_018165
Length: 148
Transcript: NM_018165
Exon
Length: 144
Transcript: NM_018165
Length: 144
Transcript: NM_018165
Exon
Length: 117
Transcript: NM_018165
Length: 117
Transcript: NM_018165
Exon
Length: 69
Transcript: NM_018165
Length: 69
Transcript: NM_018165
Exon
Length: 99
Transcript: NM_018165
Length: 99
Transcript: NM_018165
Exon
Length: 86
Transcript: NM_018165
Length: 86
Transcript: NM_018165
Exon
Length: 92
Transcript: NM_018165
Length: 92
Transcript: NM_018165
Exon
Length: 214
Transcript: NM_018165
Length: 214
Transcript: NM_018165
Exon
Length: 142
Transcript: NM_018165
Length: 142
Transcript: NM_018165
Exon
Length: 98
Transcript: NM_018165
Length: 98
Transcript: NM_018165
Exon
Length: 277
Transcript: NM_018165
Length: 277
Transcript: NM_018165
Exon
Length: 106
Transcript: NM_018165
Length: 106
Transcript: NM_018165
Exon
Length: 643
Transcript: NM_018165
Length: 643
Transcript: NM_018165
Exon
Length: 212
Transcript: NM_018165
Length: 212
Transcript: NM_018165
Exon
Length: 186
Transcript: NM_018165
Length: 186
Transcript: NM_018165
Exon
Length: 158
Transcript: NM_018165
Length: 158
Transcript: NM_018165
Exon
Length: 264
Transcript: NM_018165
Length: 264
Transcript: NM_018165
Exon
Length: 146
Transcript: NM_018165
Length: 146
Transcript: NM_018165
Exon
Length: 158
Transcript: NM_018165
Length: 158
Transcript: NM_018165
Exon
Length: 184
Transcript: NM_018165
Length: 184
Transcript: NM_018165
Exon
Length: 211
Transcript: NM_018165
Length: 211
Transcript: NM_018165
Exon
Length: 202
Transcript: NM_018165
Length: 202
Transcript: NM_018165
Exon
Length: 156
Transcript: NM_018165
Length: 156
Transcript: NM_018165
Exon
Length: 71
Transcript: NM_018165
Length: 71
Transcript: NM_018165
Exon
Length: 217
Transcript: NM_018165
Length: 217
Transcript: NM_018165
Exon
Length: 2869
Transcript: NM_018165
Length: 2869
Transcript: NM_018165
Intron
Length: 976
Transcript: NM_018165
Length: 976
Transcript: NM_018165
Intron
Length: 9854
Transcript: NM_018165
Length: 9854
Transcript: NM_018165
Intron
Length: 6221
Transcript: NM_018165
Length: 6221
Transcript: NM_018165
Intron
Length: 3817
Transcript: NM_018165
Length: 3817
Transcript: NM_018165
Intron
Length: 6388
Transcript: NM_018165
Length: 6388
Transcript: NM_018165
Intron
Length: 3299
Transcript: NM_018165
Length: 3299
Transcript: NM_018165
Intron
Length: 3554
Transcript: NM_018165
Length: 3554
Transcript: NM_018165
Intron
Length: 2658
Transcript: NM_018165
Length: 2658
Transcript: NM_018165
Intron
Length: 7138
Transcript: NM_018165
Length: 7138
Transcript: NM_018165
Intron
Length: 5566
Transcript: NM_018165
Length: 5566
Transcript: NM_018165
Intron
Length: 1523
Transcript: NM_018165
Length: 1523
Transcript: NM_018165
Intron
Length: 9734
Transcript: NM_018165
Length: 9734
Transcript: NM_018165
Intron
Length: 1805
Transcript: NM_018165
Length: 1805
Transcript: NM_018165
Intron
Length: 5395
Transcript: NM_018165
Length: 5395
Transcript: NM_018165
Intron
Length: 5580
Transcript: NM_018165
Length: 5580
Transcript: NM_018165
Intron
Length: 14265
Transcript: NM_018165
Length: 14265
Transcript: NM_018165
Intron
Length: 1559
Transcript: NM_018165
Length: 1559
Transcript: NM_018165
Intron
Length: 664
Transcript: NM_018165
Length: 664
Transcript: NM_018165
Intron
Length: 7225
Transcript: NM_018165
Length: 7225
Transcript: NM_018165
Intron
Length: 2355
Transcript: NM_018165
Length: 2355
Transcript: NM_018165
Intron
Length: 12307
Transcript: NM_018165
Length: 12307
Transcript: NM_018165
Intron
Length: 556
Transcript: NM_018165
Length: 556
Transcript: NM_018165
Intron
Length: 1314
Transcript: NM_018165
Length: 1314
Transcript: NM_018165
Intron
Length: 6887
Transcript: NM_018165
Length: 6887
Transcript: NM_018165
Intron
Length: 3906
Transcript: NM_018165
Length: 3906
Transcript: NM_018165
Intron
Length: 109
Transcript: NM_018165
Length: 109
Transcript: NM_018165
Intron
Length: 2185
Transcript: NM_018165
Length: 2185
Transcript: NM_018165
Reaction
Expected peak: 314
21.2M
refseq_PB1.F3
refseq_PB1.R3
Expected peak: 314
21.2M
refseq_PB1.F3
refseq_PB1.R3
Exon
Length: 88
Transcript: NM_018313
Length: 88
Transcript: NM_018313
Exon
Length: 150
Transcript: NM_018313
Length: 150
Transcript: NM_018313
Exon
Length: 98
Transcript: NM_018313
Length: 98
Transcript: NM_018313
Exon
Length: 148
Transcript: NM_018313
Length: 148
Transcript: NM_018313
Exon
Length: 144
Transcript: NM_018313
Length: 144
Transcript: NM_018313
Exon
Length: 117
Transcript: NM_018313
Length: 117
Transcript: NM_018313
Exon
Length: 69
Transcript: NM_018313
Length: 69
Transcript: NM_018313
Exon
Length: 99
Transcript: NM_018313
Length: 99
Transcript: NM_018313
Exon
Length: 86
Transcript: NM_018313
Length: 86
Transcript: NM_018313
Exon
Length: 96
Transcript: NM_018313
Length: 96
Transcript: NM_018313
Exon
Length: 92
Transcript: NM_018313
Length: 92
Transcript: NM_018313
Exon
Length: 214
Transcript: NM_018313
Length: 214
Transcript: NM_018313
Exon
Length: 142
Transcript: NM_018313
Length: 142
Transcript: NM_018313
Exon
Length: 98
Transcript: NM_018313
Length: 98
Transcript: NM_018313
Exon
Length: 277
Transcript: NM_018313
Length: 277
Transcript: NM_018313
Exon
Length: 106
Transcript: NM_018313
Length: 106
Transcript: NM_018313
Exon
Length: 643
Transcript: NM_018313
Length: 643
Transcript: NM_018313
Exon
Length: 212
Transcript: NM_018313
Length: 212
Transcript: NM_018313
Exon
Length: 186
Transcript: NM_018313
Length: 186
Transcript: NM_018313
Exon
Length: 83
Transcript: NM_018313
Length: 83
Transcript: NM_018313
Exon
Length: 264
Transcript: NM_018313
Length: 264
Transcript: NM_018313
Exon
Length: 146
Transcript: NM_018313
Length: 146
Transcript: NM_018313
Exon
Length: 158
Transcript: NM_018313
Length: 158
Transcript: NM_018313
Exon
Length: 184
Transcript: NM_018313
Length: 184
Transcript: NM_018313
Exon
Length: 130
Transcript: NM_018313
Length: 130
Transcript: NM_018313
Exon
Length: 202
Transcript: NM_018313
Length: 202
Transcript: NM_018313
Exon
Length: 156
Transcript: NM_018313
Length: 156
Transcript: NM_018313
Exon
Length: 71
Transcript: NM_018313
Length: 71
Transcript: NM_018313
Exon
Length: 217
Transcript: NM_018313
Length: 217
Transcript: NM_018313
Exon
Length: 2869
Transcript: NM_018313
Length: 2869
Transcript: NM_018313
Intron
Length: 6025
Transcript: NM_018313
Length: 6025
Transcript: NM_018313
Intron
Length: 976
Transcript: NM_018313
Length: 976
Transcript: NM_018313
Intron
Length: 9854
Transcript: NM_018313
Length: 9854
Transcript: NM_018313
Intron
Length: 6221
Transcript: NM_018313
Length: 6221
Transcript: NM_018313
Intron
Length: 3817
Transcript: NM_018313
Length: 3817
Transcript: NM_018313
Intron
Length: 6388
Transcript: NM_018313
Length: 6388
Transcript: NM_018313
Intron
Length: 3299
Transcript: NM_018313
Length: 3299
Transcript: NM_018313
Intron
Length: 3554
Transcript: NM_018313
Length: 3554
Transcript: NM_018313
Intron
Length: 1360
Transcript: NM_018313
Length: 1360
Transcript: NM_018313
Intron
Length: 1202
Transcript: NM_018313
Length: 1202
Transcript: NM_018313
Intron
Length: 7138
Transcript: NM_018313
Length: 7138
Transcript: NM_018313
Intron
Length: 5566
Transcript: NM_018313
Length: 5566
Transcript: NM_018313
Intron
Length: 1523
Transcript: NM_018313
Length: 1523
Transcript: NM_018313
Intron
Length: 9734
Transcript: NM_018313
Length: 9734
Transcript: NM_018313
Intron
Length: 1805
Transcript: NM_018313
Length: 1805
Transcript: NM_018313
Intron
Length: 5395
Transcript: NM_018313
Length: 5395
Transcript: NM_018313
Intron
Length: 5580
Transcript: NM_018313
Length: 5580
Transcript: NM_018313
Intron
Length: 14265
Transcript: NM_018313
Length: 14265
Transcript: NM_018313
Intron
Length: 1634
Transcript: NM_018313
Length: 1634
Transcript: NM_018313
Intron
Length: 664
Transcript: NM_018313
Length: 664
Transcript: NM_018313
Intron
Length: 7225
Transcript: NM_018313
Length: 7225
Transcript: NM_018313
Intron
Length: 2355
Transcript: NM_018313
Length: 2355
Transcript: NM_018313
Intron
Length: 12307
Transcript: NM_018313
Length: 12307
Transcript: NM_018313
Intron
Length: 556
Transcript: NM_018313
Length: 556
Transcript: NM_018313
Intron
Length: 1395
Transcript: NM_018313
Length: 1395
Transcript: NM_018313
Intron
Length: 6887
Transcript: NM_018313
Length: 6887
Transcript: NM_018313
Intron
Length: 3906
Transcript: NM_018313
Length: 3906
Transcript: NM_018313
Intron
Length: 109
Transcript: NM_018313
Length: 109
Transcript: NM_018313
Intron
Length: 2185
Transcript: NM_018313
Length: 2185
Transcript: NM_018313
Reaction
Expected peak: 314
21.2M
refseq_PB1.F3
refseq_PB1.R3
Expected peak: 314
21.2M
refseq_PB1.F3
refseq_PB1.R3
Exon
Length: 141
Transcript: NM_181042
Length: 141
Transcript: NM_181042
Exon
Length: 98
Transcript: NM_181042
Length: 98
Transcript: NM_181042
Exon
Length: 148
Transcript: NM_181042
Length: 148
Transcript: NM_181042
Exon
Length: 144
Transcript: NM_181042
Length: 144
Transcript: NM_181042
Exon
Length: 117
Transcript: NM_181042
Length: 117
Transcript: NM_181042
Exon
Length: 69
Transcript: NM_181042
Length: 69
Transcript: NM_181042
Exon
Length: 99
Transcript: NM_181042
Length: 99
Transcript: NM_181042
Exon
Length: 86
Transcript: NM_181042
Length: 86
Transcript: NM_181042
Exon
Length: 96
Transcript: NM_181042
Length: 96
Transcript: NM_181042
Exon
Length: 92
Transcript: NM_181042
Length: 92
Transcript: NM_181042
Exon
Length: 214
Transcript: NM_181042
Length: 214
Transcript: NM_181042
Exon
Length: 142
Transcript: NM_181042
Length: 142
Transcript: NM_181042
Exon
Length: 98
Transcript: NM_181042
Length: 98
Transcript: NM_181042
Exon
Length: 277
Transcript: NM_181042
Length: 277
Transcript: NM_181042
Exon
Length: 106
Transcript: NM_181042
Length: 106
Transcript: NM_181042
Exon
Length: 643
Transcript: NM_181042
Length: 643
Transcript: NM_181042
Exon
Length: 212
Transcript: NM_181042
Length: 212
Transcript: NM_181042
Exon
Length: 186
Transcript: NM_181042
Length: 186
Transcript: NM_181042
Exon
Length: 158
Transcript: NM_181042
Length: 158
Transcript: NM_181042
Exon
Length: 264
Transcript: NM_181042
Length: 264
Transcript: NM_181042
Exon
Length: 146
Transcript: NM_181042
Length: 146
Transcript: NM_181042
Exon
Length: 158
Transcript: NM_181042
Length: 158
Transcript: NM_181042
Exon
Length: 184
Transcript: NM_181042
Length: 184
Transcript: NM_181042
Exon
Length: 211
Transcript: NM_181042
Length: 211
Transcript: NM_181042
Exon
Length: 202
Transcript: NM_181042
Length: 202
Transcript: NM_181042
Exon
Length: 71
Transcript: NM_181042
Length: 71
Transcript: NM_181042
Exon
Length: 217
Transcript: NM_181042
Length: 217
Transcript: NM_181042
Exon
Length: 2869
Transcript: NM_181042
Length: 2869
Transcript: NM_181042
Intron
Length: 976
Transcript: NM_181042
Length: 976
Transcript: NM_181042
Intron
Length: 9854
Transcript: NM_181042
Length: 9854
Transcript: NM_181042
Intron
Length: 6221
Transcript: NM_181042
Length: 6221
Transcript: NM_181042
Intron
Length: 3817
Transcript: NM_181042
Length: 3817
Transcript: NM_181042
Intron
Length: 6388
Transcript: NM_181042
Length: 6388
Transcript: NM_181042
Intron
Length: 3299
Transcript: NM_181042
Length: 3299
Transcript: NM_181042
Intron
Length: 3554
Transcript: NM_181042
Length: 3554
Transcript: NM_181042
Intron
Length: 1360
Transcript: NM_181042
Length: 1360
Transcript: NM_181042
Intron
Length: 1202
Transcript: NM_181042
Length: 1202
Transcript: NM_181042
Intron
Length: 7138
Transcript: NM_181042
Length: 7138
Transcript: NM_181042
Intron
Length: 5566
Transcript: NM_181042
Length: 5566
Transcript: NM_181042
Intron
Length: 1523
Transcript: NM_181042
Length: 1523
Transcript: NM_181042
Intron
Length: 9734
Transcript: NM_181042
Length: 9734
Transcript: NM_181042
Intron
Length: 1805
Transcript: NM_181042
Length: 1805
Transcript: NM_181042
Intron
Length: 5395
Transcript: NM_181042
Length: 5395
Transcript: NM_181042
Intron
Length: 5580
Transcript: NM_181042
Length: 5580
Transcript: NM_181042
Intron
Length: 14265
Transcript: NM_181042
Length: 14265
Transcript: NM_181042
Intron
Length: 1559
Transcript: NM_181042
Length: 1559
Transcript: NM_181042
Intron
Length: 664
Transcript: NM_181042
Length: 664
Transcript: NM_181042
Intron
Length: 7225
Transcript: NM_181042
Length: 7225
Transcript: NM_181042
Intron
Length: 2355
Transcript: NM_181042
Length: 2355
Transcript: NM_181042
Intron
Length: 12307
Transcript: NM_181042
Length: 12307
Transcript: NM_181042
Intron
Length: 556
Transcript: NM_181042
Length: 556
Transcript: NM_181042
Intron
Length: 1314
Transcript: NM_181042
Length: 1314
Transcript: NM_181042
Intron
Length: 10949
Transcript: NM_181042
Length: 10949
Transcript: NM_181042
Intron
Length: 109
Transcript: NM_181042
Length: 109
Transcript: NM_181042
Intron
Length: 2185
Transcript: NM_181042
Length: 2185
Transcript: NM_181042
Reaction
Expected peak: 158
41M
refseq_PB1.F3
refseq_PB1.R3
Expected peak: 158
41M
refseq_PB1.F3
refseq_PB1.R3
refseq_PB1.R3
CCACTCCTTGGTTCATCACAC
CCACTCCTTGGTTCATCACAC
refseq_PB1.F3
TGGCTACATCCTGTTCAGCA
TGGCTACATCCTGTTCAGCA