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Supplementary data
RBFOX2 enforces the mesenchymal splicing signature in normal and cancer tissues
7. 26 switch-like targets from epithelium and mesenchyme (fetal colon) in RBFOX2, MBNL1, PTBP and ESRP knockdowns
Transcript map
: MINK1 Control (MDA-MB-231)
Exon
Length: 253
Transcript: NM_001024937
Length: 253
Transcript: NM_001024937
Exon
Length: 11
Transcript: NM_001024937
Length: 11
Transcript: NM_001024937
Exon
Length: 12
Transcript: NM_001024937
Length: 12
Transcript: NM_001024937
Exon
Length: 111
Transcript: NM_001024937
Length: 111
Transcript: NM_001024937
Exon
Length: 91
Transcript: NM_001024937
Length: 91
Transcript: NM_001024937
Exon
Length: 131
Transcript: NM_001024937
Length: 131
Transcript: NM_001024937
Exon
Length: 55
Transcript: NM_001024937
Length: 55
Transcript: NM_001024937
Exon
Length: 79
Transcript: NM_001024937
Length: 79
Transcript: NM_001024937
Exon
Length: 176
Transcript: NM_001024937
Length: 176
Transcript: NM_001024937
Exon
Length: 70
Transcript: NM_001024937
Length: 70
Transcript: NM_001024937
Exon
Length: 211
Transcript: NM_001024937
Length: 211
Transcript: NM_001024937
Exon
Length: 117
Transcript: NM_001024937
Length: 117
Transcript: NM_001024937
Exon
Length: 219
Transcript: NM_001024937
Length: 219
Transcript: NM_001024937
Exon
Length: 174
Transcript: NM_001024937
Length: 174
Transcript: NM_001024937
Exon
Length: 201
Transcript: NM_001024937
Length: 201
Transcript: NM_001024937
Exon
Length: 86
Transcript: NM_001024937
Length: 86
Transcript: NM_001024937
Exon
Length: 111
Transcript: NM_001024937
Length: 111
Transcript: NM_001024937
Exon
Length: 113
Transcript: NM_001024937
Length: 113
Transcript: NM_001024937
Exon
Length: 89
Transcript: NM_001024937
Length: 89
Transcript: NM_001024937
Exon
Length: 164
Transcript: NM_001024937
Length: 164
Transcript: NM_001024937
Exon
Length: 106
Transcript: NM_001024937
Length: 106
Transcript: NM_001024937
Exon
Length: 138
Transcript: NM_001024937
Length: 138
Transcript: NM_001024937
Exon
Length: 109
Transcript: NM_001024937
Length: 109
Transcript: NM_001024937
Exon
Length: 168
Transcript: NM_001024937
Length: 168
Transcript: NM_001024937
Exon
Length: 144
Transcript: NM_001024937
Length: 144
Transcript: NM_001024937
Exon
Length: 135
Transcript: NM_001024937
Length: 135
Transcript: NM_001024937
Exon
Length: 101
Transcript: NM_001024937
Length: 101
Transcript: NM_001024937
Exon
Length: 150
Transcript: NM_001024937
Length: 150
Transcript: NM_001024937
Exon
Length: 160
Transcript: NM_001024937
Length: 160
Transcript: NM_001024937
Exon
Length: 140
Transcript: NM_001024937
Length: 140
Transcript: NM_001024937
Exon
Length: 861
Transcript: NM_001024937
Length: 861
Transcript: NM_001024937
Intron
Length: 20643
Transcript: NM_001024937
Length: 20643
Transcript: NM_001024937
Intron
Length: 5980
Transcript: NM_001024937
Length: 5980
Transcript: NM_001024937
Intron
Length: 18191
Transcript: NM_001024937
Length: 18191
Transcript: NM_001024937
Intron
Length: 438
Transcript: NM_001024937
Length: 438
Transcript: NM_001024937
Intron
Length: 480
Transcript: NM_001024937
Length: 480
Transcript: NM_001024937
Intron
Length: 297
Transcript: NM_001024937
Length: 297
Transcript: NM_001024937
Intron
Length: 154
Transcript: NM_001024937
Length: 154
Transcript: NM_001024937
Intron
Length: 252
Transcript: NM_001024937
Length: 252
Transcript: NM_001024937
Intron
Length: 483
Transcript: NM_001024937
Length: 483
Transcript: NM_001024937
Intron
Length: 400
Transcript: NM_001024937
Length: 400
Transcript: NM_001024937
Intron
Length: 1855
Transcript: NM_001024937
Length: 1855
Transcript: NM_001024937
Intron
Length: 753
Transcript: NM_001024937
Length: 753
Transcript: NM_001024937
Intron
Length: 215
Transcript: NM_001024937
Length: 215
Transcript: NM_001024937
Intron
Length: 385
Transcript: NM_001024937
Length: 385
Transcript: NM_001024937
Intron
Length: 432
Transcript: NM_001024937
Length: 432
Transcript: NM_001024937
Intron
Length: 167
Transcript: NM_001024937
Length: 167
Transcript: NM_001024937
Intron
Length: 143
Transcript: NM_001024937
Length: 143
Transcript: NM_001024937
Intron
Length: 210
Transcript: NM_001024937
Length: 210
Transcript: NM_001024937
Intron
Length: 366
Transcript: NM_001024937
Length: 366
Transcript: NM_001024937
Intron
Length: 390
Transcript: NM_001024937
Length: 390
Transcript: NM_001024937
Intron
Length: 80
Transcript: NM_001024937
Length: 80
Transcript: NM_001024937
Intron
Length: 213
Transcript: NM_001024937
Length: 213
Transcript: NM_001024937
Intron
Length: 441
Transcript: NM_001024937
Length: 441
Transcript: NM_001024937
Intron
Length: 107
Transcript: NM_001024937
Length: 107
Transcript: NM_001024937
Intron
Length: 204
Transcript: NM_001024937
Length: 204
Transcript: NM_001024937
Intron
Length: 170
Transcript: NM_001024937
Length: 170
Transcript: NM_001024937
Intron
Length: 89
Transcript: NM_001024937
Length: 89
Transcript: NM_001024937
Intron
Length: 86
Transcript: NM_001024937
Length: 86
Transcript: NM_001024937
Intron
Length: 85
Transcript: NM_001024937
Length: 85
Transcript: NM_001024937
Intron
Length: 390
Transcript: NM_001024937
Length: 390
Transcript: NM_001024937
Reaction
Expected peak: 247
35M
refseq_MINK1.F3
refseq_MINK1.R3
Expected peak: 247
35M
refseq_MINK1.F3
refseq_MINK1.R3
Exon
Length: 253
Transcript: NM_015716
Length: 253
Transcript: NM_015716
Exon
Length: 11
Transcript: NM_015716
Length: 11
Transcript: NM_015716
Exon
Length: 12
Transcript: NM_015716
Length: 12
Transcript: NM_015716
Exon
Length: 111
Transcript: NM_015716
Length: 111
Transcript: NM_015716
Exon
Length: 91
Transcript: NM_015716
Length: 91
Transcript: NM_015716
Exon
Length: 131
Transcript: NM_015716
Length: 131
Transcript: NM_015716
Exon
Length: 55
Transcript: NM_015716
Length: 55
Transcript: NM_015716
Exon
Length: 79
Transcript: NM_015716
Length: 79
Transcript: NM_015716
Exon
Length: 176
Transcript: NM_015716
Length: 176
Transcript: NM_015716
Exon
Length: 70
Transcript: NM_015716
Length: 70
Transcript: NM_015716
Exon
Length: 211
Transcript: NM_015716
Length: 211
Transcript: NM_015716
Exon
Length: 117
Transcript: NM_015716
Length: 117
Transcript: NM_015716
Exon
Length: 219
Transcript: NM_015716
Length: 219
Transcript: NM_015716
Exon
Length: 174
Transcript: NM_015716
Length: 174
Transcript: NM_015716
Exon
Length: 261
Transcript: NM_015716
Length: 261
Transcript: NM_015716
Exon
Length: 86
Transcript: NM_015716
Length: 86
Transcript: NM_015716
Exon
Length: 113
Transcript: NM_015716
Length: 113
Transcript: NM_015716
Exon
Length: 89
Transcript: NM_015716
Length: 89
Transcript: NM_015716
Exon
Length: 164
Transcript: NM_015716
Length: 164
Transcript: NM_015716
Exon
Length: 106
Transcript: NM_015716
Length: 106
Transcript: NM_015716
Exon
Length: 138
Transcript: NM_015716
Length: 138
Transcript: NM_015716
Exon
Length: 109
Transcript: NM_015716
Length: 109
Transcript: NM_015716
Exon
Length: 168
Transcript: NM_015716
Length: 168
Transcript: NM_015716
Exon
Length: 144
Transcript: NM_015716
Length: 144
Transcript: NM_015716
Exon
Length: 135
Transcript: NM_015716
Length: 135
Transcript: NM_015716
Exon
Length: 101
Transcript: NM_015716
Length: 101
Transcript: NM_015716
Exon
Length: 150
Transcript: NM_015716
Length: 150
Transcript: NM_015716
Exon
Length: 160
Transcript: NM_015716
Length: 160
Transcript: NM_015716
Exon
Length: 140
Transcript: NM_015716
Length: 140
Transcript: NM_015716
Exon
Length: 861
Transcript: NM_015716
Length: 861
Transcript: NM_015716
Intron
Length: 20643
Transcript: NM_015716
Length: 20643
Transcript: NM_015716
Intron
Length: 5980
Transcript: NM_015716
Length: 5980
Transcript: NM_015716
Intron
Length: 18191
Transcript: NM_015716
Length: 18191
Transcript: NM_015716
Intron
Length: 438
Transcript: NM_015716
Length: 438
Transcript: NM_015716
Intron
Length: 480
Transcript: NM_015716
Length: 480
Transcript: NM_015716
Intron
Length: 297
Transcript: NM_015716
Length: 297
Transcript: NM_015716
Intron
Length: 154
Transcript: NM_015716
Length: 154
Transcript: NM_015716
Intron
Length: 252
Transcript: NM_015716
Length: 252
Transcript: NM_015716
Intron
Length: 483
Transcript: NM_015716
Length: 483
Transcript: NM_015716
Intron
Length: 400
Transcript: NM_015716
Length: 400
Transcript: NM_015716
Intron
Length: 1855
Transcript: NM_015716
Length: 1855
Transcript: NM_015716
Intron
Length: 753
Transcript: NM_015716
Length: 753
Transcript: NM_015716
Intron
Length: 215
Transcript: NM_015716
Length: 215
Transcript: NM_015716
Intron
Length: 325
Transcript: NM_015716
Length: 325
Transcript: NM_015716
Intron
Length: 432
Transcript: NM_015716
Length: 432
Transcript: NM_015716
Intron
Length: 421
Transcript: NM_015716
Length: 421
Transcript: NM_015716
Intron
Length: 210
Transcript: NM_015716
Length: 210
Transcript: NM_015716
Intron
Length: 366
Transcript: NM_015716
Length: 366
Transcript: NM_015716
Intron
Length: 390
Transcript: NM_015716
Length: 390
Transcript: NM_015716
Intron
Length: 80
Transcript: NM_015716
Length: 80
Transcript: NM_015716
Intron
Length: 213
Transcript: NM_015716
Length: 213
Transcript: NM_015716
Intron
Length: 441
Transcript: NM_015716
Length: 441
Transcript: NM_015716
Intron
Length: 107
Transcript: NM_015716
Length: 107
Transcript: NM_015716
Intron
Length: 204
Transcript: NM_015716
Length: 204
Transcript: NM_015716
Intron
Length: 170
Transcript: NM_015716
Length: 170
Transcript: NM_015716
Intron
Length: 89
Transcript: NM_015716
Length: 89
Transcript: NM_015716
Intron
Length: 86
Transcript: NM_015716
Length: 86
Transcript: NM_015716
Intron
Length: 85
Transcript: NM_015716
Length: 85
Transcript: NM_015716
Intron
Length: 390
Transcript: NM_015716
Length: 390
Transcript: NM_015716
Reaction
Expected peak: 136
5M
refseq_MINK1.F3
refseq_MINK1.R3
Expected peak: 136
5M
refseq_MINK1.F3
refseq_MINK1.R3
Exon
Length: 253
Transcript: NM_153827
Length: 253
Transcript: NM_153827
Exon
Length: 11
Transcript: NM_153827
Length: 11
Transcript: NM_153827
Exon
Length: 12
Transcript: NM_153827
Length: 12
Transcript: NM_153827
Exon
Length: 111
Transcript: NM_153827
Length: 111
Transcript: NM_153827
Exon
Length: 91
Transcript: NM_153827
Length: 91
Transcript: NM_153827
Exon
Length: 131
Transcript: NM_153827
Length: 131
Transcript: NM_153827
Exon
Length: 55
Transcript: NM_153827
Length: 55
Transcript: NM_153827
Exon
Length: 79
Transcript: NM_153827
Length: 79
Transcript: NM_153827
Exon
Length: 176
Transcript: NM_153827
Length: 176
Transcript: NM_153827
Exon
Length: 70
Transcript: NM_153827
Length: 70
Transcript: NM_153827
Exon
Length: 211
Transcript: NM_153827
Length: 211
Transcript: NM_153827
Exon
Length: 117
Transcript: NM_153827
Length: 117
Transcript: NM_153827
Exon
Length: 219
Transcript: NM_153827
Length: 219
Transcript: NM_153827
Exon
Length: 174
Transcript: NM_153827
Length: 174
Transcript: NM_153827
Exon
Length: 261
Transcript: NM_153827
Length: 261
Transcript: NM_153827
Exon
Length: 86
Transcript: NM_153827
Length: 86
Transcript: NM_153827
Exon
Length: 111
Transcript: NM_153827
Length: 111
Transcript: NM_153827
Exon
Length: 113
Transcript: NM_153827
Length: 113
Transcript: NM_153827
Exon
Length: 89
Transcript: NM_153827
Length: 89
Transcript: NM_153827
Exon
Length: 164
Transcript: NM_153827
Length: 164
Transcript: NM_153827
Exon
Length: 106
Transcript: NM_153827
Length: 106
Transcript: NM_153827
Exon
Length: 138
Transcript: NM_153827
Length: 138
Transcript: NM_153827
Exon
Length: 109
Transcript: NM_153827
Length: 109
Transcript: NM_153827
Exon
Length: 168
Transcript: NM_153827
Length: 168
Transcript: NM_153827
Exon
Length: 144
Transcript: NM_153827
Length: 144
Transcript: NM_153827
Exon
Length: 135
Transcript: NM_153827
Length: 135
Transcript: NM_153827
Exon
Length: 101
Transcript: NM_153827
Length: 101
Transcript: NM_153827
Exon
Length: 150
Transcript: NM_153827
Length: 150
Transcript: NM_153827
Exon
Length: 160
Transcript: NM_153827
Length: 160
Transcript: NM_153827
Exon
Length: 140
Transcript: NM_153827
Length: 140
Transcript: NM_153827
Exon
Length: 861
Transcript: NM_153827
Length: 861
Transcript: NM_153827
Intron
Length: 20643
Transcript: NM_153827
Length: 20643
Transcript: NM_153827
Intron
Length: 5980
Transcript: NM_153827
Length: 5980
Transcript: NM_153827
Intron
Length: 18191
Transcript: NM_153827
Length: 18191
Transcript: NM_153827
Intron
Length: 438
Transcript: NM_153827
Length: 438
Transcript: NM_153827
Intron
Length: 480
Transcript: NM_153827
Length: 480
Transcript: NM_153827
Intron
Length: 297
Transcript: NM_153827
Length: 297
Transcript: NM_153827
Intron
Length: 154
Transcript: NM_153827
Length: 154
Transcript: NM_153827
Intron
Length: 252
Transcript: NM_153827
Length: 252
Transcript: NM_153827
Intron
Length: 483
Transcript: NM_153827
Length: 483
Transcript: NM_153827
Intron
Length: 400
Transcript: NM_153827
Length: 400
Transcript: NM_153827
Intron
Length: 1855
Transcript: NM_153827
Length: 1855
Transcript: NM_153827
Intron
Length: 753
Transcript: NM_153827
Length: 753
Transcript: NM_153827
Intron
Length: 215
Transcript: NM_153827
Length: 215
Transcript: NM_153827
Intron
Length: 325
Transcript: NM_153827
Length: 325
Transcript: NM_153827
Intron
Length: 432
Transcript: NM_153827
Length: 432
Transcript: NM_153827
Intron
Length: 167
Transcript: NM_153827
Length: 167
Transcript: NM_153827
Intron
Length: 143
Transcript: NM_153827
Length: 143
Transcript: NM_153827
Intron
Length: 210
Transcript: NM_153827
Length: 210
Transcript: NM_153827
Intron
Length: 366
Transcript: NM_153827
Length: 366
Transcript: NM_153827
Intron
Length: 390
Transcript: NM_153827
Length: 390
Transcript: NM_153827
Intron
Length: 80
Transcript: NM_153827
Length: 80
Transcript: NM_153827
Intron
Length: 213
Transcript: NM_153827
Length: 213
Transcript: NM_153827
Intron
Length: 441
Transcript: NM_153827
Length: 441
Transcript: NM_153827
Intron
Length: 107
Transcript: NM_153827
Length: 107
Transcript: NM_153827
Intron
Length: 204
Transcript: NM_153827
Length: 204
Transcript: NM_153827
Intron
Length: 170
Transcript: NM_153827
Length: 170
Transcript: NM_153827
Intron
Length: 89
Transcript: NM_153827
Length: 89
Transcript: NM_153827
Intron
Length: 86
Transcript: NM_153827
Length: 86
Transcript: NM_153827
Intron
Length: 85
Transcript: NM_153827
Length: 85
Transcript: NM_153827
Intron
Length: 390
Transcript: NM_153827
Length: 390
Transcript: NM_153827
Reaction
Expected peak: 247
35M
refseq_MINK1.F3
refseq_MINK1.R3
Expected peak: 247
35M
refseq_MINK1.F3
refseq_MINK1.R3
Exon
Length: 253
Transcript: NM_170663
Length: 253
Transcript: NM_170663
Exon
Length: 11
Transcript: NM_170663
Length: 11
Transcript: NM_170663
Exon
Length: 12
Transcript: NM_170663
Length: 12
Transcript: NM_170663
Exon
Length: 111
Transcript: NM_170663
Length: 111
Transcript: NM_170663
Exon
Length: 91
Transcript: NM_170663
Length: 91
Transcript: NM_170663
Exon
Length: 131
Transcript: NM_170663
Length: 131
Transcript: NM_170663
Exon
Length: 55
Transcript: NM_170663
Length: 55
Transcript: NM_170663
Exon
Length: 79
Transcript: NM_170663
Length: 79
Transcript: NM_170663
Exon
Length: 176
Transcript: NM_170663
Length: 176
Transcript: NM_170663
Exon
Length: 70
Transcript: NM_170663
Length: 70
Transcript: NM_170663
Exon
Length: 211
Transcript: NM_170663
Length: 211
Transcript: NM_170663
Exon
Length: 117
Transcript: NM_170663
Length: 117
Transcript: NM_170663
Exon
Length: 219
Transcript: NM_170663
Length: 219
Transcript: NM_170663
Exon
Length: 174
Transcript: NM_170663
Length: 174
Transcript: NM_170663
Exon
Length: 261
Transcript: NM_170663
Length: 261
Transcript: NM_170663
Exon
Length: 86
Transcript: NM_170663
Length: 86
Transcript: NM_170663
Exon
Length: 113
Transcript: NM_170663
Length: 113
Transcript: NM_170663
Exon
Length: 89
Transcript: NM_170663
Length: 89
Transcript: NM_170663
Exon
Length: 24
Transcript: NM_170663
Length: 24
Transcript: NM_170663
Exon
Length: 164
Transcript: NM_170663
Length: 164
Transcript: NM_170663
Exon
Length: 106
Transcript: NM_170663
Length: 106
Transcript: NM_170663
Exon
Length: 138
Transcript: NM_170663
Length: 138
Transcript: NM_170663
Exon
Length: 109
Transcript: NM_170663
Length: 109
Transcript: NM_170663
Exon
Length: 168
Transcript: NM_170663
Length: 168
Transcript: NM_170663
Exon
Length: 144
Transcript: NM_170663
Length: 144
Transcript: NM_170663
Exon
Length: 135
Transcript: NM_170663
Length: 135
Transcript: NM_170663
Exon
Length: 101
Transcript: NM_170663
Length: 101
Transcript: NM_170663
Exon
Length: 150
Transcript: NM_170663
Length: 150
Transcript: NM_170663
Exon
Length: 160
Transcript: NM_170663
Length: 160
Transcript: NM_170663
Exon
Length: 140
Transcript: NM_170663
Length: 140
Transcript: NM_170663
Exon
Length: 861
Transcript: NM_170663
Length: 861
Transcript: NM_170663
Intron
Length: 20643
Transcript: NM_170663
Length: 20643
Transcript: NM_170663
Intron
Length: 5980
Transcript: NM_170663
Length: 5980
Transcript: NM_170663
Intron
Length: 18191
Transcript: NM_170663
Length: 18191
Transcript: NM_170663
Intron
Length: 438
Transcript: NM_170663
Length: 438
Transcript: NM_170663
Intron
Length: 480
Transcript: NM_170663
Length: 480
Transcript: NM_170663
Intron
Length: 297
Transcript: NM_170663
Length: 297
Transcript: NM_170663
Intron
Length: 154
Transcript: NM_170663
Length: 154
Transcript: NM_170663
Intron
Length: 252
Transcript: NM_170663
Length: 252
Transcript: NM_170663
Intron
Length: 483
Transcript: NM_170663
Length: 483
Transcript: NM_170663
Intron
Length: 400
Transcript: NM_170663
Length: 400
Transcript: NM_170663
Intron
Length: 1855
Transcript: NM_170663
Length: 1855
Transcript: NM_170663
Intron
Length: 753
Transcript: NM_170663
Length: 753
Transcript: NM_170663
Intron
Length: 215
Transcript: NM_170663
Length: 215
Transcript: NM_170663
Intron
Length: 325
Transcript: NM_170663
Length: 325
Transcript: NM_170663
Intron
Length: 432
Transcript: NM_170663
Length: 432
Transcript: NM_170663
Intron
Length: 421
Transcript: NM_170663
Length: 421
Transcript: NM_170663
Intron
Length: 210
Transcript: NM_170663
Length: 210
Transcript: NM_170663
Intron
Length: 218
Transcript: NM_170663
Length: 218
Transcript: NM_170663
Intron
Length: 124
Transcript: NM_170663
Length: 124
Transcript: NM_170663
Intron
Length: 390
Transcript: NM_170663
Length: 390
Transcript: NM_170663
Intron
Length: 80
Transcript: NM_170663
Length: 80
Transcript: NM_170663
Intron
Length: 213
Transcript: NM_170663
Length: 213
Transcript: NM_170663
Intron
Length: 441
Transcript: NM_170663
Length: 441
Transcript: NM_170663
Intron
Length: 107
Transcript: NM_170663
Length: 107
Transcript: NM_170663
Intron
Length: 204
Transcript: NM_170663
Length: 204
Transcript: NM_170663
Intron
Length: 170
Transcript: NM_170663
Length: 170
Transcript: NM_170663
Intron
Length: 89
Transcript: NM_170663
Length: 89
Transcript: NM_170663
Intron
Length: 86
Transcript: NM_170663
Length: 86
Transcript: NM_170663
Intron
Length: 85
Transcript: NM_170663
Length: 85
Transcript: NM_170663
Intron
Length: 390
Transcript: NM_170663
Length: 390
Transcript: NM_170663
Reaction
Expected peak: 136
5M
refseq_MINK1.F3
refseq_MINK1.R3
Expected peak: 136
5M
refseq_MINK1.F3
refseq_MINK1.R3
refseq_MINK1.R3
AGGCTGGAAGGACGCTGTC
AGGCTGGAAGGACGCTGTC
refseq_MINK1.F3
ACCTCATCTATCGCCACTGC
ACCTCATCTATCGCCACTGC