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Supplementary data
RBFOX2 enforces the mesenchymal splicing signature in normal and cancer tissues
7. 26 switch-like targets from epithelium and mesenchyme (fetal colon) in RBFOX2, MBNL1, PTBP and ESRP knockdowns
Transcript map
: M-RIP Control (MDA-MB-231)
Exon
Length: 179
Transcript: NM_015134
Length: 179
Transcript: NM_015134
Exon
Length: 78
Transcript: NM_015134
Length: 78
Transcript: NM_015134
Exon
Length: 66
Transcript: NM_015134
Length: 66
Transcript: NM_015134
Exon
Length: 152
Transcript: NM_015134
Length: 152
Transcript: NM_015134
Exon
Length: 85
Transcript: NM_015134
Length: 85
Transcript: NM_015134
Exon
Length: 232
Transcript: NM_015134
Length: 232
Transcript: NM_015134
Exon
Length: 160
Transcript: NM_015134
Length: 160
Transcript: NM_015134
Exon
Length: 139
Transcript: NM_015134
Length: 139
Transcript: NM_015134
Exon
Length: 114
Transcript: NM_015134
Length: 114
Transcript: NM_015134
Exon
Length: 57
Transcript: NM_015134
Length: 57
Transcript: NM_015134
Exon
Length: 69
Transcript: NM_015134
Length: 69
Transcript: NM_015134
Exon
Length: 90
Transcript: NM_015134
Length: 90
Transcript: NM_015134
Exon
Length: 110
Transcript: NM_015134
Length: 110
Transcript: NM_015134
Exon
Length: 571
Transcript: NM_015134
Length: 571
Transcript: NM_015134
Exon
Length: 117
Transcript: NM_015134
Length: 117
Transcript: NM_015134
Exon
Length: 148
Transcript: NM_015134
Length: 148
Transcript: NM_015134
Exon
Length: 118
Transcript: NM_015134
Length: 118
Transcript: NM_015134
Exon
Length: 160
Transcript: NM_015134
Length: 160
Transcript: NM_015134
Exon
Length: 120
Transcript: NM_015134
Length: 120
Transcript: NM_015134
Exon
Length: 87
Transcript: NM_015134
Length: 87
Transcript: NM_015134
Exon
Length: 163
Transcript: NM_015134
Length: 163
Transcript: NM_015134
Exon
Length: 86
Transcript: NM_015134
Length: 86
Transcript: NM_015134
Exon
Length: 738
Transcript: NM_015134
Length: 738
Transcript: NM_015134
Intron
Length: 32738
Transcript: NM_015134
Length: 32738
Transcript: NM_015134
Intron
Length: 2223
Transcript: NM_015134
Length: 2223
Transcript: NM_015134
Intron
Length: 48625
Transcript: NM_015134
Length: 48625
Transcript: NM_015134
Intron
Length: 4763
Transcript: NM_015134
Length: 4763
Transcript: NM_015134
Intron
Length: 4517
Transcript: NM_015134
Length: 4517
Transcript: NM_015134
Intron
Length: 1465
Transcript: NM_015134
Length: 1465
Transcript: NM_015134
Intron
Length: 4551
Transcript: NM_015134
Length: 4551
Transcript: NM_015134
Intron
Length: 790
Transcript: NM_015134
Length: 790
Transcript: NM_015134
Intron
Length: 2366
Transcript: NM_015134
Length: 2366
Transcript: NM_015134
Intron
Length: 1226
Transcript: NM_015134
Length: 1226
Transcript: NM_015134
Intron
Length: 2756
Transcript: NM_015134
Length: 2756
Transcript: NM_015134
Intron
Length: 4072
Transcript: NM_015134
Length: 4072
Transcript: NM_015134
Intron
Length: 4016
Transcript: NM_015134
Length: 4016
Transcript: NM_015134
Intron
Length: 2237
Transcript: NM_015134
Length: 2237
Transcript: NM_015134
Intron
Length: 10361
Transcript: NM_015134
Length: 10361
Transcript: NM_015134
Intron
Length: 832
Transcript: NM_015134
Length: 832
Transcript: NM_015134
Intron
Length: 1100
Transcript: NM_015134
Length: 1100
Transcript: NM_015134
Intron
Length: 1217
Transcript: NM_015134
Length: 1217
Transcript: NM_015134
Intron
Length: 1013
Transcript: NM_015134
Length: 1013
Transcript: NM_015134
Intron
Length: 737
Transcript: NM_015134
Length: 737
Transcript: NM_015134
Intron
Length: 2590
Transcript: NM_015134
Length: 2590
Transcript: NM_015134
Intron
Length: 4734
Transcript: NM_015134
Length: 4734
Transcript: NM_015134
Reaction
Expected peak: 114
41.7M
refseq_M-RIP.F1
refseq_M-RIP.R1
Expected peak: 114
41.7M
refseq_M-RIP.F1
refseq_M-RIP.R1
Exon
Length: 179
Transcript: NM_201274
Length: 179
Transcript: NM_201274
Exon
Length: 78
Transcript: NM_201274
Length: 78
Transcript: NM_201274
Exon
Length: 66
Transcript: NM_201274
Length: 66
Transcript: NM_201274
Exon
Length: 152
Transcript: NM_201274
Length: 152
Transcript: NM_201274
Exon
Length: 85
Transcript: NM_201274
Length: 85
Transcript: NM_201274
Exon
Length: 232
Transcript: NM_201274
Length: 232
Transcript: NM_201274
Exon
Length: 160
Transcript: NM_201274
Length: 160
Transcript: NM_201274
Exon
Length: 139
Transcript: NM_201274
Length: 139
Transcript: NM_201274
Exon
Length: 114
Transcript: NM_201274
Length: 114
Transcript: NM_201274
Exon
Length: 57
Transcript: NM_201274
Length: 57
Transcript: NM_201274
Exon
Length: 69
Transcript: NM_201274
Length: 69
Transcript: NM_201274
Exon
Length: 90
Transcript: NM_201274
Length: 90
Transcript: NM_201274
Exon
Length: 110
Transcript: NM_201274
Length: 110
Transcript: NM_201274
Exon
Length: 571
Transcript: NM_201274
Length: 571
Transcript: NM_201274
Exon
Length: 117
Transcript: NM_201274
Length: 117
Transcript: NM_201274
Exon
Length: 148
Transcript: NM_201274
Length: 148
Transcript: NM_201274
Exon
Length: 118
Transcript: NM_201274
Length: 118
Transcript: NM_201274
Exon
Length: 160
Transcript: NM_201274
Length: 160
Transcript: NM_201274
Exon
Length: 120
Transcript: NM_201274
Length: 120
Transcript: NM_201274
Exon
Length: 87
Transcript: NM_201274
Length: 87
Transcript: NM_201274
Exon
Length: 163
Transcript: NM_201274
Length: 163
Transcript: NM_201274
Exon
Length: 86
Transcript: NM_201274
Length: 86
Transcript: NM_201274
Exon
Length: 63
Transcript: NM_201274
Length: 63
Transcript: NM_201274
Exon
Length: 737
Transcript: NM_201274
Length: 737
Transcript: NM_201274
Intron
Length: 32738
Transcript: NM_201274
Length: 32738
Transcript: NM_201274
Intron
Length: 2223
Transcript: NM_201274
Length: 2223
Transcript: NM_201274
Intron
Length: 48625
Transcript: NM_201274
Length: 48625
Transcript: NM_201274
Intron
Length: 4763
Transcript: NM_201274
Length: 4763
Transcript: NM_201274
Intron
Length: 4517
Transcript: NM_201274
Length: 4517
Transcript: NM_201274
Intron
Length: 1465
Transcript: NM_201274
Length: 1465
Transcript: NM_201274
Intron
Length: 4551
Transcript: NM_201274
Length: 4551
Transcript: NM_201274
Intron
Length: 790
Transcript: NM_201274
Length: 790
Transcript: NM_201274
Intron
Length: 2366
Transcript: NM_201274
Length: 2366
Transcript: NM_201274
Intron
Length: 1226
Transcript: NM_201274
Length: 1226
Transcript: NM_201274
Intron
Length: 2756
Transcript: NM_201274
Length: 2756
Transcript: NM_201274
Intron
Length: 4072
Transcript: NM_201274
Length: 4072
Transcript: NM_201274
Intron
Length: 4016
Transcript: NM_201274
Length: 4016
Transcript: NM_201274
Intron
Length: 2237
Transcript: NM_201274
Length: 2237
Transcript: NM_201274
Intron
Length: 10361
Transcript: NM_201274
Length: 10361
Transcript: NM_201274
Intron
Length: 832
Transcript: NM_201274
Length: 832
Transcript: NM_201274
Intron
Length: 1100
Transcript: NM_201274
Length: 1100
Transcript: NM_201274
Intron
Length: 1217
Transcript: NM_201274
Length: 1217
Transcript: NM_201274
Intron
Length: 1013
Transcript: NM_201274
Length: 1013
Transcript: NM_201274
Intron
Length: 737
Transcript: NM_201274
Length: 737
Transcript: NM_201274
Intron
Length: 2590
Transcript: NM_201274
Length: 2590
Transcript: NM_201274
Intron
Length: 518
Transcript: NM_201274
Length: 518
Transcript: NM_201274
Intron
Length: 4153
Transcript: NM_201274
Length: 4153
Transcript: NM_201274
Reaction
Expected peak: 177
41.6M
refseq_M-RIP.F1
refseq_M-RIP.R1
Expected peak: 177
41.6M
refseq_M-RIP.F1
refseq_M-RIP.R1
refseq_M-RIP.F1
AAAGCAACCCTGACTTCTTGAA
AAAGCAACCCTGACTTCTTGAA
refseq_M-RIP.R1
AGAGCTTCAACCGTTCTTGC
AGAGCTTCAACCGTTCTTGC